Brock's Syndrome

Atelectasis of the right middle pulmonary lobe, with chronic pneumonitis. (Dorland, 27th ed)

Synonym
Middle Lobe Syndrome
Brock's Syndrome

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	5 (33.33)	23.3326
1990's	2 (13.33)	12.5806
2000's	4 (26.67)	18.1394
2010's	3 (20.00)	28.8240
2020's	1 (6.67)	9.53

Drug	Relationship Strength	Studies
methanol	low	1
albendazole	low	1
theophylline	low	1
guaifenesin	low	1
phenobarbital	low	1
prednisolone	low	2
prednisone	low	2
chloramphenicol	low	1
edetic acid	low	1
methacholine chloride	low	1
phencyclidine	low	1
ephedrine	low	1
streptomycin	low	1
cephalosporin c	low	1
cefminox	low	1
clindamycin	low	1
phenylephrine hydrochloride	low	1

Protein Targets (306)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Beta-lactamase	1	0	0	1
Luciferase	1	0	0	1
glp-1 receptor, partial	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
RAR-related orphan receptor gamma	6	0	0	6
ATAD5 protein, partial	1	0	0	1
Fumarate hydratase	1	0	0	1
TDP1 protein	7	0	0	7
GLI family zinc finger 3	6	0	0	6
AR protein	8	0	0	8
caspase 7, apoptosis-related cysteine protease	1	0	0	1
nuclear receptor subfamily 1, group I, member 3	4	0	0	4
progesterone receptor	4	0	0	4
glucocorticoid receptor [Homo sapiens]	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
retinoid X nuclear receptor alpha	2	0	0	2
estrogen-related nuclear receptor alpha	7	0	0	7
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	5	0	0	5
estrogen nuclear receptor alpha	7	0	0	7
polyprotein	1	0	0	1
67.9K protein	2	0	0	2
peroxisome proliferator activated receptor gamma	3	0	0	3
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
caspase-3	1	0	0	1
IDH1	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	7	0	0	7
aryl hydrocarbon receptor	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Histone H2A.x	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
chromobox protein homolog 1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	5	0	0	5
histone deacetylase 9 isoform 3	1	0	0	1
heat shock protein beta-1	2	0	0	2
mitogen-activated protein kinase 1	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
geminin	6	0	0	6
Vif	0	0	0	1
peripheral myelin protein 22	3	0	0	3
survival motor neuron protein isoform d	2	0	0	2
muscleblind-like protein 1 isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
lamin isoform A-delta10	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
ATP-binding cassette sub-family C member 3	0	4	0	4
Multidrug resistance-associated protein 4	0	4	0	4
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Bile salt export pump	0	8	0	8
Interferon beta	3	0	0	3
Cellular tumor antigen p53	6	0	0	6
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Canalicular multispecific organic anion transporter 1	0	3	0	3
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
interleukin 8	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
EWS/FLI fusion protein	2	0	0	2
G	1	0	0	1
cytochrome P450 2D6	2	0	0	2
activating transcription factor 6	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	2	0	0	2
streptokinase A precursor	0	0	1	1
lethal factor (plasmid)	2	0	0	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
HLA class I histocompatibility antigen, B alpha chain	1	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Cytochrome P450 3A4	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Inositol hexakisphosphate kinase 1	1	0	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	1	0	0	1
Protein-arginine deiminase type-4	0	3	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Histamine H2 receptor	1	0	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
flap endonuclease 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
GALC protein	2	0	0	2
Microtubule-associated protein tau	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
Bloom syndrome protein isoform 1	2	0	0	2
galanin receptor type 3	0	1	0	1
thyroid stimulating hormone receptor	2	0	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	3
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Muscarinic acetylcholine receptor M5	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
thioredoxin reductase	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Spike glycoprotein	1	0	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	2	11
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Cytochrome P450 2C9	0	1	0	1
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Histamine H1 receptor	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	1	0	1
Estrogen receptor beta	0	2	0	2
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
pregnane X receptor	1	0	0	1
thioredoxin glutathione reductase	1	0	0	1
estrogen receptor 2 (ER beta)	1	0	0	1
vitamin D3 receptor isoform VDRA	2	0	0	2
nuclear receptor ROR-gamma isoform 1	1	0	0	1
Nuclear receptor ROR-gamma	2	0	0	2
cytochrome P450 2D6 isoform 1	1	0	0	1
histone acetyltransferase KAT2A isoform 1	1	0	0	1
muscarinic acetylcholine receptor M1	1	0	0	1
Bile salt export pump	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
phosphopantetheinyl transferase	1	0	0	1
USP1 protein, partial	1	0	0	1
GLS protein	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
arylsulfatase A	1	0	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Potassium channel subfamily K member 2	0	0	1	1
Renin	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Adenosine receptor A3	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Adenosine receptor A1	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	2	5
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A1	0	2	1	5
Adenosine receptor A2a	0	1	0	3
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
TAR DNA-binding protein 43	1	0	0	1
Chitotriosidase-1	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
ATP-dependent phosphofructokinase	1	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research

Studies (15)

Protein Targets (306)

Brock's Syndrome

Synonyms(2)

Research

Studies (15)

Drugs Studied (18)

Protein Targets (306)