Roles > hydrogen donor
Page last updated: 2024-08-05 15:30:25

hydrogen donor

A molecular entity that can undergo oxidation by the loss of hydrogen atom(s).

ChEBI ID: 17499

Members (1)

MemberDefinitionClass
1,2-diaminobenzeneA phenylenediamine in which the two amino groups are ortho to each other.1,2-phenylenediamine

Research

Studies (286)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199032 (11.19)18.7374
1990's38 (13.29)18.2507
2000's54 (18.88)29.6817
2010's101 (35.31)24.3611
2020's61 (21.33)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (0.34%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other297 (99.66%)84.16%

Protein Targets (69)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-lipoxygenase, partialHomo sapiens (human)Potency31.622811
acetylcholinesteraseHomo sapiens (human)Potency4.404422
activating transcription factor 6Homo sapiens (human)Potency13.800611
Alpha-synucleinHomo sapiens (human)Potency12.589311
AR proteinHomo sapiens (human)Potency27.362599
aryl hydrocarbon receptorHomo sapiens (human)Potency21.873133
Ataxin-2Homo sapiens (human)Potency2.433711
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency4.646322
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency8.634911
caspase-1 isoform alpha precursorHomo sapiens (human)Potency39.810711
caspase-3Homo sapiens (human)Potency8.634911
Caspase-7Homo sapiens (human)Potency31.622811
Cellular tumor antigen p53Homo sapiens (human)Potency27.306011
cytochrome P450 2C9, partialHomo sapiens (human)Potency31.705511
cytochrome P450 2D6Homo sapiens (human)Potency11.249611
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency19.952622
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency2.825811
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency2.433711
estrogen nuclear receptor alphaHomo sapiens (human)Potency23.995867
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency30.619622
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency9.6703910
farnesoid X nuclear receptorHomo sapiens (human)Potency27.528622
Fumarate hydrataseHomo sapiens (human)Potency28.183811
GVesicular stomatitis virusPotency31.705511
GABA theta subunitRattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency19.952611
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency19.952611
GLI family zinc finger 3Homo sapiens (human)Potency22.161622
GLS proteinHomo sapiens (human)Potency39.810711
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency38.410022
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency54.482711
heat shock protein beta-1Homo sapiens (human)Potency19.529222
histone deacetylase 9 isoform 3Homo sapiens (human)Potency23.102022
Histone H2A.xCricetulus griseus (Chinese hamster)Potency61.727222
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency31.705511
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency48.966211
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency31.705512
Interferon betaHomo sapiens (human)Potency31.705511
LuciferasePhotinus pyralis (common eastern firefly)Potency2.208522
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency11.832144
Nuclear receptor ROR-gammaHomo sapiens (human)Potency0.188311
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency31.749033
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency8.707611
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency77.606211
polyproteinZika virusPotency28.183811
pregnane X nuclear receptorHomo sapiens (human)Potency21.588622
pregnane X receptorRattus norvegicus (Norway rat)Potency39.810711
progesterone receptorHomo sapiens (human)Potency45.917422
RAR-related orphan receptor gammaMus musculus (house mouse)Potency2.559422
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency3.827533
retinoid X nuclear receptor alphaHomo sapiens (human)Potency18.433822
survival motor neuron protein isoform dHomo sapiens (human)Potency11.220211
TDP1 proteinHomo sapiens (human)Potency16.011023
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency23.270222
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency5.494122
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency54.482711