Cow Pox

A mild, eruptive skin disease of milk cows caused by COWPOX VIRUS, with lesions occurring principally on the udder and teats. Human infection may occur while milking an infected animal.

Synonym
Cowpox
Cow Pox

Excerpt	Reference
"The efficacy of cidofovir for treatment of cowpox virus infection in BALB/c mice was investigated in an effort to evaluate new therapies for virulent orthopoxvirus infections of the respiratory tract in a small animal model."	( Bray, M; Huggins, JW; Kefauver, D; Martinez, M; Smee, DF; Thompson, E, 2000)
"Intraperitoneal treatment of cowpox virus-challenged C57Bl/6 mice with 0."	( Altmann, SE; Blaney, JE; Dodd, LE; Dyall, J; Jahrling, PB; Johnson, RF; Paragas, J; Smith, AL, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	3 (7.50)	23.3326
1990's	6 (15.00)	12.5806
2000's	22 (55.00)	18.1394
2010's	6 (15.00)	28.8240
2020's	3 (7.50)	9.53

Drug	Relationship Strength	Studies
adenine	low	2
cytosine	low	16
thymine	low	1
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1
mitoxantrone	low	1
thymidine	low	1
idoxuridine	low	1
colchicine	low	1
cycloheximide	low	1
cytarabine	low	1
streptomycin	low	1
etoposide	low	1
ribavirin	low	1
piperacillin	low	1
octenidine	low	1
adefovir	low	1
cidofovir anhydrous	low	19
adenosine	low	1
9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine	low	1
4'-thiothymidine	low	1
foxes	low	2
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine	low	1
organophosphonates	low	17
demecolcine	low	1
arachidonic acid	low	1
(north)-methanocarbathymidine	low	1
mycophenolic acid	low	1
cmx 001	low	1
methisazone	low	1
phenylephrine hydrochloride	low	1
amoxicillin-potassium clavulanate combination	low	1
aceclidine	low	1
2'-deoxy-4'-thiocytidine	low	1
st-246	low	2
interleukin-8	low	1
acyclovir	low	1
eye	low	2

Protein Targets (570)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, THYMIDINE KINASE	0	1	0	1
Chain A, THYMIDINE KINASE	0	1	0	1
Thymidine kinase, cytosolic	0	5	0	8
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
Chain A, Cruzipain	2	0	0	2
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	5	0	0	5
15-lipoxygenase, partial	3	0	0	3
ATAD5 protein, partial	4	0	0	4
NFKB1 protein, partial	2	0	0	2
TDP1 protein	15	0	0	15
Thrombopoietin	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
thyroid stimulating hormone receptor	4	0	0	4
regulator of G-protein signaling 4	3	0	0	3
EWS/FLI fusion protein	6	0	0	6
67.9K protein	9	0	0	9
Parkin	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	10	0	0	10
cytochrome P450 2D6 isoform 1	3	0	0	3
cellular tumor antigen p53 isoform a	5	0	0	5
cytochrome P450 2C19 precursor	2	0	0	2
cytochrome P450 2C9 precursor	2	0	0	2
chromobox protein homolog 1	8	0	0	8
flap endonuclease 1	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
survival motor neuron protein isoform d	6	0	0	6
cytochrome P450 3A4 isoform 1	7	0	0	7
M-phase phosphoprotein 8	2	0	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	7	0	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Bromodomain-containing protein 4	0	1	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Integrin beta-3	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Integrin alpha-IIb	2	0	0	2
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Serine/threonine-protein kinase pim-1	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit delta	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	7	0	0	7
Casein kinase II subunit alpha'	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	7	0	0	7
Proteinase-activated receptor 1	0	0	0	1
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	7	0	0	7
Sodium-dependent serotonin transporter	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	3
Serine/threonine-protein kinase mTOR	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	4	0	0	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Serine/threonine-protein kinase PLK1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit beta-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit beta-2	7	0	0	7
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	0	1
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	7	0	0	7
Gamma-aminobutyric acid receptor subunit epsilon	7	0	0	7
Serine/threonine-protein kinase PLK3	0	2	0	2
Serine/threonine-protein kinase PLK2	0	1	0	1
ATP-dependent phosphofructokinase	4	0	0	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	3	0	0	3
Thymidine kinase	0	4	0	5
phosphopantetheinyl transferase	4	0	0	4
GLS protein	2	0	0	2
Smad3	4	0	0	4
arylsulfatase A	4	0	0	4
activating transcription factor 6	5	0	0	5
Histone H2A.x	7	0	0	7
Bloom syndrome protein isoform 1	4	0	0	4
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lamin isoform A-delta10	9	0	0	9
Solute carrier family 22 member 1	0	1	0	2
ATP-binding cassette sub-family C member 3	0	6	0	6
Multidrug resistance-associated protein 4	0	6	0	6
Solute carrier family 22 member 6	0	0	0	3
Bile salt export pump	0	2	0	2
Bile salt export pump	0	9	0	9
Purine nucleoside phosphorylase	0	2	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	2	0	2
Cytochrome P450 2J2	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	3	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Canalicular multispecific organic anion transporter 1	0	7	0	8
Thymidine kinase	0	2	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
thyroid hormone receptor beta isoform 2	9	0	0	9
Phosphoribosyl pyrophosphate synthase-associated protein 2	0	1	0	2
Adenylate kinase isoenzyme 1	0	0	0	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Adenosine deaminase	0	1	0	3
Capsid protein	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	9	0	0	9
AR protein	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
glucocorticoid receptor [Homo sapiens]	11	0	0	11
estrogen-related nuclear receptor alpha	9	0	0	9
pregnane X nuclear receptor	6	0	0	6
estrogen nuclear receptor alpha	13	0	0	13
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
heat shock protein beta-1	2	0	0	2
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	8	1	0	9
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	4	1	0	5
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	10	0	0	10
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
retinoid X nuclear receptor alpha	5	0	0	5
NPYLR7B	0	0	1	1
IDH1	6	0	0	6
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
mitogen-activated protein kinase 1	2	0	0	2
nuclear receptor ROR-gamma isoform 1	4	0	0	4
peripheral myelin protein 22	7	0	0	7
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
Epidermal growth factor receptor	0	2	0	2
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	3	2	6
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	3	0	3
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	3
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	3
Adenosine receptor A1	0	1	1	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	2	5
Adenosine receptor A2b	0	0	1	2
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	2	6
Adenosine receptor A2a	0	1	1	2
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Beta-lactamase	2	0	0	2
USP1 protein, partial	5	0	0	5
Microtubule-associated protein tau	1	0	0	1
thioredoxin glutathione reductase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
vitamin D3 receptor isoform VDRA	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA polymerase kappa isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	0	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Aromatase	0	1	0	1
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Prostaglandin G/H synthase 2	0	0	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Calmodulin	0	0	0	1
Prostaglandin G/H synthase 2	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	6
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	3
Luciferase	1	0	0	1
interleukin 8	3	0	0	3
endonuclease IV	2	0	0	2
PAX8	0	0	0	2
pregnane X receptor	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
Fumarate hydratase	4	0	0	4
PPM1D protein	4	0	0	4
GLI family zinc finger 3	5	0	0	5
estrogen receptor 2 (ER beta)	3	0	0	3
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
farnesoid X nuclear receptor	4	0	0	4
polyprotein	4	0	0	4
glucocerebrosidase	1	0	0	1
peroxisome proliferator-activated receptor delta	4	0	0	4
peroxisome proliferator activated receptor gamma	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
aryl hydrocarbon receptor	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
nuclear receptor subfamily 0 group B member 1	0	2	0	2
thyroid hormone receptor beta isoform a	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	2	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	6	0	0	6
geminin	10	0	0	10
muscleblind-like protein 1 isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	3	0	0	3
lethal factor (plasmid)	3	0	0	3
neuropeptide S receptor isoform A	1	0	0	1
Solute carrier family 22 member 3	0	2	0	2
Interferon beta	6	0	0	6
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
Cellular tumor antigen p53	9	0	0	9
ATP-dependent translocase ABCB1	0	2	0	2
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	4	0	6
Cytochrome P450 3A4	0	3	0	3
Tubulin alpha-3C chain	0	2	2	5
ATP-dependent translocase ABCB1	0	2	0	2
Nuclear receptor ROR-gamma	3	0	0	3
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	4	0	4
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
glp-1 receptor, partial	6	0	0	6
progesterone receptor	4	0	0	4
P53	1	0	0	1
RPL19A	0	0	1	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	2	2
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	2	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Alpha-synuclein	2	0	0	2
Spike glycoprotein	1	0	2	3
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
G	2	0	0	2
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase iota isoform a (long)	4	0	0	4
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	0	0	2
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Inositol hexakisphosphate kinase 1	2	0	0	2
Deoxynucleoside kinase	0	1	0	1
cytochrome P450 2C9, partial	2	0	0	2
Deoxycytidine kinase	0	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
caspase 7, apoptosis-related cysteine protease	1	0	0	1
caspase-3	1	0	0	1
thyroid stimulating hormone receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	2	1	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	9
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Integrase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Vpr	3	0	0	3
Thymidine phosphorylase	0	0	0	2
cytochrome P450 2D6	1	0	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
dopamine D1 receptor	1	0	0	1
WRN	1	0	0	1
apical membrane antigen 1, AMA1	1	0	0	1
DNA polymerase III, partial	1	0	0	1
hypothetical protein, conserved	1	0	0	1
nonstructural protein 1	0	1	0	1
LANA	0	0	0	1
pyruvate kinase	1	0	0	1
phospholipase A2, group III	0	1	0	1
interferon gamma precursor	0	0	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
huntingtin isoform 2	1	0	0	1
protein AF-9 isoform a	0	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Amyloid-beta precursor protein	1	0	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Proto-oncogene tyrosine-protein kinase ROS	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Cytochrome P450 2D6	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Tyrosine-protein kinase BTK	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Multidrug and toxin extrusion protein 2	0	1	0	1
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
phosphoglycerate kinase	1	0	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
acetylcholinesterase	1	0	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
GALC protein	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-7	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
NS5	0	0	1	1
alpha-galactosidase	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Envelope phospholipase F13	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
Thymidine phosphorylase	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine phosphorylase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (40)

Protein Targets (570)

Cow Pox

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (40)

Drugs Studied (43)

Protein Targets (570)