Lipomatosis

A disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling LIPOMA.

Synonym
Lipomatosis

Excerpt	Reference
"Pelvic lipomatosis is a rare, relatively self-limiting disease characterized by the overgrowth of unencapsulated lipomatous tissue within the pelvis."	( Crawford, ED; Dumbadze, I; Katz, DL; Vester, JW, 1978)
"Macrodactylia fibrolipomatosis is a form of macrodactyly noticed soon after birth."	( Alizadeh, A; McKowne, F; Yaghmai, I, 1976)
"Epidural lipomatosis is a condition in which excess adipose tissue is deposited circumferentially about the spinal cord in the epidural space."	( Brown, FD; Erickson, RK; Fessler, RG; Johnson, DL; Kranzler, L; Reid, SA, 1992)
"Epidural lipomatosis is a rare disease, most often associated with chronic administration of exogenous steroids."	( Carpentier, AF; Delattre, JY; Jalladeau, E; Napolitano, M, 2000)
"Orbital lipomatosis is a potential complication of retrobulbar steroid injections."	( Boynton, JR; Gupta, OP; Markowitch, W; Quatela, VC; Sabini, P, 2003)
"Pelvic lipomatosis is diagnosed radiologically."	( Berdou, R; Osterhage, HR, 2003)
"Epidural lipomatosis is a rare but severe complication of long-term corticoid treatment."	( Burkhardt, N; Hamann, GF, 2006)
"Spinal epidural lipomatosis is the excessive deposition of unencapsulated fat in the epidural space."	( Gupta, R; Gupta, V; Kumar, AN; Madhavan, SM; Sharma, SK, 2007)
"Spinal epidural lipomatosis is a rare side effect of chronic steroid therapy that may occur with relatively short-term, low-dose regimens."	( Gupta, R; Gupta, V; Kumar, AN; Madhavan, SM; Sharma, SK, 2007)
"Spinal epidural lipomatosis is a rare disorder that can manifest with progressive neurological deficits."	( Gangi, A; Kaur, S; Tok, CH, 2011)
"Finally, lipomatosis is currently classified as a painful form (adiposis dolorosa or Dercum's disease) or benign symmetric multiple form, also known as Launois-Bensaude syndrome or Madelung's disease, which are sometimes related to mitochondrial DNA mutations, but are usually promoted by alcohol."	( Balavoine, AS; Bertrand-Escouflaire, N; Bourdelle-Hego, MF; Cortet, C; Defrance, F; Devemy, F; Dieudonne, L; Douillard, C; Duvivier, E; Evrard, A; Gheerbrand, D; Girardot, C; Gumuche, S; Hober, C; Karrouz, W; Lacroix, D; Lamblin, B; Lemaire, C; Merlen, E; Mouton, F; Mycinski, B; Ryndak, A; Topolinski, H; Vantyghem, MC; Weill, J; Wémeau, JL, 2012)
"Spinal epidural lipomatosis is a rare condition of adipose tissue hypertrophy in the epidural space."	( Billings, F; Hoyt, MR, 2012)
"Spinal epidural lipomatosis is a complex disorder caused by hypertrophy of adipose tissue located in the spinal epidural space."	( Clerici, J; MacLaran, S, 2014)
"Small bowel lipomatosis is an occasional finding in patients with advanced renal cancer on pazopanib and is not seen with other TKIs."	( Alam, S; Ghosh-Ray, S; Gogbashian, A; Lakhani, A; Nathan, P; Padhani, A; Sharma, A, 2023)

Excerpt	Reference
"Mediastinal lipomatosis has been described in adults and is a well recognized cause of mediastinal enlargement."	( Katz, JA; Shukla, LW; Wagner, ML, 1988)
"Multiple symmetric lipomatosis has been proposed to be associated with impaired catecholamine-responsiveness of hypertrophic adipose tissue at the level of beta-adrenergic receptors or adenylate cyclase respectively."	( Kather, H; Simon, B, 1981)
"Spinal epidural lipomatosis has been reported frequently in association with chronic systemic corticosteroid therapy, but thus far only one case has been attributed to local epidural corticosteroid injections."	( Lavyne, MH; Sandberg, DI, 1999)
"Epidural lipomatosis has been implicated as a cause or contributor of symptomatic lumbar spinal stenosis."	( Botwin, KP; Sakalkale, DP, 2004)
"The presence of lipomatosis has no relation with the response to treatment to pazopanib and this is a unique finding seen only in patients on pazopanib."	( Alam, S; Ghosh-Ray, S; Gogbashian, A; Lakhani, A; Nathan, P; Padhani, A; Sharma, A, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	97 (36.06)	23.3326
1990's	34 (12.64)	12.5806
2000's	64 (23.79)	18.1394
2010's	66 (24.54)	28.8240
2020's	8 (2.97)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	1
adenine	low	1
chlorine	low	1
salicylic acid	low	12
glycine	low	1
glycerol	low	3
hydrogen	low	1
4-aminobenzoic acid	low	1
pyridoxine	low	1
uric acid	low	3
1-anilino-8-naphthalenesulfonate	low	9
albuterol	low	1
diatrizoic acid	low	2
theophylline	low	2
amlodipine	low	1
azathioprine	low	2
baclofen	low	1
diazepam	low	1
diclofenac	low	1
pentetic acid	low	2
fentanyl	low	1
gabapentin	low	1
lidocaine	low	1
isoniazid	low	1
2-propanol	low	1
isoproterenol	low	1
mechlorethamine	low	1
procarbazine	low	1
thalidomide	low	1
tolbutamide	low	1
prednisolone	low	16
phentolamine	low	1
thyroxine	low	1
penicillamine	low	1
prednisone	low	28
methylprednisolone acetate	low	1
lysine	low	1
tyrosine	low	1
leucine	low	2
asparagine	low	1
alizarin	low	1
triamcinolone acetonide	low	4
dehydrocholic acid	low	1
methylprednisolone	low	10
pyridostigmine bromide	low	1
indazoles	low	1
thiazoles	low	1
cyproterone acetate	low	1
ethambutol	low	1
d-alpha tocopherol	low	1
stavudine	low	1
streptomycin	low	1
platinum	low	1
gadolinium	low	4
barium sulfate	low	15
ozone	low	1
trolamine salicylate	low	2
tetradecanoylphorbol acetate	low	1
fluorides	low	1
triamcinolone	low	4
fludrocortisone	low	1
propiconazole	low	3
nitrosobis(2-oxopropyl)amine	low	2
finasteride	low	1
lamivudine	low	1
trazodone hydrochloride	low	1
fluorodeoxyglucose f18	low	4
zoledronic acid	low	1
rosiglitazone	low	1
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone	low	2
peptide elongation factor 2	low	1
technetium tc 99m pentetate	low	1
lenalidomide	low	1
deoxycholic acid	low	2
cortisone	low	4
ritonavir	low	2
glycogen	low	1
inositol 3-phosphate	low	2
retinol	low	2
dipyrone	low	1
capsaicin	low	1
alpha-chymotrypsin	low	2
bilirubin	low	1
phenylephrine hydrochloride	low	1
sirolimus	low	2
fluticasone	low	1
su 11248	low	1
barium	low	1
indinavir sulfate	low	3
selenium	low	1
everolimus	low	1
gadolinium dtpa	low	4
bentiromide	low	1
pazopanib	low	1
oxadiazoles	low	1
ptc 124	low	1
trametinib	low	1
jaw	low	1
cholecystokinin	low	1
glucagon	low	3
phosphatidylcholines	low	1
bucladesine	low	1
sodium pertechnetate tc 99m	low	1
oxytetracycline, anhydrous	low	1
byl719	low	1
transforming growth factor beta	low	1
bassianolide	low	1
hyaluronoglucosaminidase	low	1
cyclosporine	low	2
guanosine triphosphate	low	3
guanine	low	1
rifampin	low	1
alcian blue	low	1
eye	low	3
trypsinogen	low	1
leptin	low	2
pyrimidinones	low	1

Protein Targets (1,424)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	19	0	0	19
USP1 protein, partial	20	0	0	20
TDP1 protein	35	0	0	35
vitamin D3 receptor isoform VDRA	12	0	0	12
importin subunit beta-1 isoform 1	6	0	0	6
flap endonuclease 1	8	0	0	8
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	33	0	0	33
DNA polymerase kappa isoform 1	8	0	0	8
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	2	3
Beta-lactamase	0	1	0	1
Transthyretin	0	2	2	7
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	2	0	2
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	3	7	10
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	2	3
Guanine nucleotide-binding protein G	4	0	0	4
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	5	6
Mitogen-activated protein kinase 14	0	1	6	7
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
RAR-related orphan receptor gamma	25	0	0	25
GLI family zinc finger 3	28	0	0	28
AR protein	41	0	0	41
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
retinoic acid nuclear receptor alpha variant 1	19	0	0	19
retinoid X nuclear receptor alpha	21	0	0	21
estrogen nuclear receptor alpha	44	0	0	44
peroxisome proliferator-activated receptor delta	17	0	0	17
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
activating transcription factor 6	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	9	0	0	9
Histone H2A.x	7	0	0	7
thyroid hormone receptor beta isoform a	8	0	0	8
heat shock protein beta-1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
lamin isoform A-delta10	28	0	0	28
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Glutamate receptor 2	11	0	0	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Genome polyprotein	0	0	1	1
thyroid stimulating hormone receptor	8	0	0	8
glucocorticoid receptor [Homo sapiens]	31	0	0	31
chromobox protein homolog 1	16	0	0	16
transcriptional regulator ERG isoform 3	4	0	0	4
Polyphenol oxidase 2	0	3	0	5
Cellular tumor antigen p53	24	1	0	25
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
Chain A, Toluene-4-monooxygenase system protein A	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
estrogen-related nuclear receptor alpha	26	0	0	26
pregnane X nuclear receptor	26	0	0	26
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	12
tumor susceptibility gene 101 protein	2	0	0	2
Bile salt export pump	0	43	0	43
Cyclin-dependent kinase 1	0	2	6	8
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	8	0	0	8
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	3	2	5
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	16	0	0	16
glp-1 receptor, partial	7	0	0	7
GLS protein	12	0	0	12
regulator of G-protein signaling 4	8	0	0	8
NPYLR7B	0	0	2	2
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	27	0	0	27
thyroid stimulating hormone receptor	8	0	0	8
peripheral myelin protein 22	13	0	0	13
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	26
Beta-2 adrenergic receptor	0	6	5	12
Beta-1 adrenergic receptor	0	4	4	8
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Beta-3 adrenergic receptor	0	3	3	6
Delta-type opioid receptor	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
Beta-2 adrenergic receptor	0	1	2	5
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Beta-2 adrenergic receptor	0	2	5	8
Canalicular multispecific organic anion transporter 1	0	23	0	23
ATP-dependent phosphofructokinase	10	0	0	10
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Luciferase	7	0	0	7
endonuclease IV	5	0	0	5
15-lipoxygenase, partial	7	0	0	7
WRN	2	0	0	2
Microtubule-associated protein tau	16	0	0	16
estrogen receptor 2 (ER beta)	11	0	0	11
G	14	0	0	14
cytochrome P450 2D6	12	0	0	12
peroxisome proliferator activated receptor gamma	18	0	0	18
aryl hydrocarbon receptor	13	0	0	13
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
histone deacetylase 9 isoform 3	2	0	0	2
mitogen-activated protein kinase 1	6	0	0	6
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
Vpr	2	0	0	2
survival motor neuron protein isoform d	6	0	0	6
cytochrome P450 3A4 isoform 1	11	0	0	11
histone acetyltransferase KAT2A isoform 1	10	0	0	10
kelch-like ECH-associated protein 1	0	0	0	2
Gamma-aminobutyric acid receptor subunit pi	11	5	2	18
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Interferon beta	19	0	0	19
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Gag-Pol polyprotein	0	3	0	3
Apoptosis regulator Bcl-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	11	5	2	18
Gamma-aminobutyric acid receptor subunit delta	11	5	2	18
Gamma-aminobutyric acid receptor subunit gamma-2	11	5	4	20
D(3) dopamine receptor	0	3	0	3
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	11	5	2	18
Gamma-aminobutyric acid receptor subunit alpha-3	11	5	2	18
Amine oxidase [flavin-containing] A	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	11	5	2	18
Gamma-aminobutyric acid receptor subunit alpha-2	11	5	2	18
Amine oxidase [flavin-containing] B	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	11	5	2	18
Gamma-aminobutyric acid receptor subunit gamma-3	11	5	2	18
Gamma-aminobutyric acid receptor subunit alpha-6	11	5	2	18
Histamine H2 receptor	5	0	1	6
Gamma-aminobutyric acid receptor subunit alpha-1	11	5	4	20
Gamma-aminobutyric acid receptor subunit beta-3	11	5	2	18
Gamma-aminobutyric acid receptor subunit beta-2	11	5	4	20
Inositol monophosphatase 1	4	0	0	4
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
RmtA	0	1	0	1
Reverse transcriptase/RNaseH	0	2	2	5
GABA theta subunit	11	5	2	18
Inositol hexakisphosphate kinase 1	14	0	0	14
Protein arginine N-methyltransferase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	11	5	2	18
cytochrome P450 2C9, partial	14	0	0	14
phosphoglycerate kinase	2	0	0	2
Chain A, Ferritin light chain	6	0	0	6
Smad3	5	0	0	5
IDH1	8	0	0	8
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	16	0	0	16
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Potassium channel subfamily K member 2	0	2	3	5
ATP-dependent translocase ABCB1	0	7	1	9
Alpha-2A adrenergic receptor	0	5	3	10
Alpha-2C adrenergic receptor	0	5	3	10
Alpha-2B adrenergic receptor	0	5	3	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Alpha-2C adrenergic receptor	0	5	3	8
Alpha-2A adrenergic receptor	0	5	3	8
Alpha-1D adrenergic receptor	0	3	3	7
Alpha-1A adrenergic receptor	0	4	4	9
Alpha-1B adrenergic receptor	0	3	3	7
5-hydroxytryptamine receptor 6	0	4	1	5
Spike glycoprotein	10	0	0	10
Sodium-dependent dopamine transporter	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Potassium channel subfamily K member 2	0	1	0	1
Carbonic anhydrase 1	0	6	0	8
Carbonic anhydrase 2	0	7	0	9
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
interleukin 8	4	0	0	4
acetylcholinesterase	8	0	0	8
phosphopantetheinyl transferase	14	0	0	14
SMAD family member 2	10	0	0	10
ATAD5 protein, partial	10	0	0	10
Fumarate hydratase	6	0	0	6
SMAD family member 3	10	0	0	10
thioredoxin glutathione reductase	5	0	0	5
EWS/FLI fusion protein	18	0	0	18
farnesoid X nuclear receptor	7	0	0	7
polyprotein	6	0	0	6
P53	1	0	0	1
Bloom syndrome protein isoform 1	9	0	0	9
peripheral myelin protein 22 isoform 1	4	0	0	4
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
thyroid hormone receptor beta isoform 2	21	0	0	21
M-phase phosphoprotein 8	4	0	0	4
muscleblind-like protein 1 isoform 1	5	0	0	5
muscarinic acetylcholine receptor M1	6	0	0	6
Bile salt export pump	0	12	0	12
Nuclear receptor ROR-gamma	7	0	0	7
Protein-arginine deiminase type-4	0	3	0	3
NFKB1 protein, partial	2	0	0	2
67.9K protein	7	0	0	7
D(1A) dopamine receptor	5	0	0	5
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, Cruzipain	5	0	0	5
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	10
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
neuropeptide S receptor isoform A	3	0	0	3
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
PPM1D protein	5	0	0	5
Bone morphogenetic protein receptor type-1B	0	0	6	6
Membrane-associated progesterone receptor component 1	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	2	4
Serine/threonine-protein kinase PLK4	0	1	6	7
ATP-dependent RNA helicase DDX3X	0	0	6	6
Pyridoxal kinase	0	0	6	7
Citron Rho-interacting kinase	0	0	6	6
Serine/threonine-protein kinase Chk1	0	1	6	7
Aurora kinase A	0	1	6	7
Cyclin-G-associated kinase	0	0	6	6
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 2	0	0	6	6
Dynamin-like 120 kDa protein, mitochondrial	0	0	6	6
Eukaryotic translation initiation factor 5B	0	0	5	5
Rho-associated protein kinase 2	0	0	6	6
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	0	6	6
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	6	6
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	0	7	7
Structural maintenance of chromosomes protein 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	2	6	8
Tyrosine-protein kinase ABL1	0	2	7	10
Epidermal growth factor receptor	0	1	6	7
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	5	5
ADP/ATP translocase 2	0	0	6	6
Protein kinase C beta type	0	1	7	8
Insulin receptor	0	1	6	7
Tyrosine-protein kinase Lck	0	1	6	7
Tyrosine-protein kinase Fyn	0	0	6	6
Glycogen phosphorylase, liver form	0	0	6	6
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Adenine phosphoribosyltransferase	0	0	5	5
Tyrosine-protein kinase Yes	0	0	6	6
Tyrosine-protein kinase Lyn	0	0	6	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	6	7
Insulin-like growth factor 1 receptor	0	0	6	6
Signal recognition particle receptor subunit alpha	0	0	6	6
Cytochrome c1, heme protein, mitochondrial	0	0	6	6
Hepatocyte growth factor receptor	0	1	6	7
Tyrosine-protein kinase HCK	0	1	6	7
Cytochrome P450 3A4	0	11	1	14
Platelet-derived growth factor receptor beta	0	4	6	10
Serine/threonine-protein kinase A-Raf	0	0	6	6
Glycogen phosphorylase, brain form	0	0	6	6
Breakpoint cluster region protein	0	0	7	8
Serine/threonine-protein kinase pim-1	0	0	6	6
Fibroblast growth factor receptor 1	0	2	6	8
DNA topoisomerase 2-alpha	0	0	6	6
Cyclin-dependent kinase 4	0	0	6	6
ADP/ATP translocase 3	0	0	6	6
Inosine-5'-monophosphate dehydrogenase 2	0	0	6	6
Proto-oncogene tyrosine-protein kinase Src	0	1	6	7
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Serine/threonine-protein kinase B-raf	0	0	6	6
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	6	6
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	1	7	8
cAMP-dependent protein kinase catalytic subunit alpha	0	0	6	6
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	6	6
Casein kinase II subunit alpha'	0	0	6	6
Ras-related protein Rab-6A	0	0	5	5
Ephrin type-A receptor 1	0	0	6	6
Multifunctional protein ADE2	0	0	6	6
cAMP-dependent protein kinase catalytic subunit gamma	0	0	5	5
cAMP-dependent protein kinase catalytic subunit beta	0	0	6	6
Ferrochelatase, mitochondrial	0	0	6	6
Ribosomal protein S6 kinase beta-1	0	0	6	6
Tyrosine-protein kinase JAK1	0	0	6	6
Beta-adrenergic receptor kinase 1	0	0	7	7
Probable ATP-dependent RNA helicase DDX6	0	0	6	6
Mitogen-activated protein kinase 3	0	0	6	6
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Deoxycytidine kinase	0	0	6	6
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Mitogen-activated protein kinase 1	0	0	6	6
Ephrin type-A receptor 2	0	0	6	6
Ephrin type-B receptor 2	0	0	6	6
Non-receptor tyrosine-protein kinase TYK2	0	0	6	6
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	6	6
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	6	6
S-adenosylmethionine synthase isoform type-2	0	0	6	6
DnaJ homolog subfamily A member 1	0	0	6	6
RAC-alpha serine/threonine-protein kinase	0	2	6	8
RAC-beta serine/threonine-protein kinase	0	0	6	6
Delta-type opioid receptor	0	3	0	3
DNA replication licensing factor MCM4	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 2	0	1	6	7
Receptor-type tyrosine-protein kinase FLT3	0	1	6	8
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	5	5
Tyrosine-protein kinase CSK	0	0	6	6
Glycine--tRNA ligase	0	0	6	6
Protein kinase C iota type	0	0	7	7
Exosome RNA helicase MTR4	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	2	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	2	4
Serine/threonine-protein kinase mTOR	0	4	4	8
Tyrosine-protein kinase Tec	0	0	6	6
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
Tyrosine-protein kinase SYK	0	0	6	6
26S proteasome regulatory subunit 6B	0	0	6	6
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Casein kinase I isoform alpha	0	1	6	7
Casein kinase I isoform delta	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	2	5
MAP kinase-activated protein kinase 2	0	0	6	6
Elongation factor Tu, mitochondrial	0	0	6	6
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	6	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	6	6
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	6	6
Glycogen synthase kinase-3 alpha	0	0	6	6
Glycogen synthase kinase-3 beta	0	0	6	6
Cyclin-dependent kinase 7	0	0	6	6
Cyclin-dependent kinase 9	0	0	6	6
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Ribosomal protein S6 kinase alpha-3	0	1	6	7
Serine/threonine-protein kinase Nek2	0	1	6	7
Serine/threonine-protein kinase Nek3	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 6	0	0	6	6
LIM domain kinase 1	0	0	6	6
LIM domain kinase 2	0	0	6	6
Mitogen-activated protein kinase 10	0	0	6	6
Tyrosine--tRNA ligase, cytoplasmic	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	1	6	7
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	6	6
Adenosine kinase	0	0	6	6
Ras-related protein Rab-10	0	0	6	6
Actin-related protein 3	0	0	6	6
Actin-related protein 2	0	0	6	6
GTP-binding nuclear protein Ran	0	0	6	6
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Cyclin-dependent kinase 3	0	0	5	5
Cyclin-dependent kinase 6	0	0	6	6
Cyclin-dependent-like kinase 5	0	0	6	6
Cyclin-dependent kinase 16	0	0	6	6
ATP-dependent 6-phosphofructokinase, platelet type	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 1	0	1	6	7
DNA topoisomerase 2-beta	0	0	6	6
Protein kinase C theta type	0	0	7	7
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	0	6	6
Focal adhesion kinase 1	0	1	6	7
Protein kinase C delta type	0	1	7	8
Tyrosine-protein kinase BTK	0	0	6	6
Activated CDC42 kinase 1	0	0	6	6
Epithelial discoidin domain-containing receptor 1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	6	8
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
Serine-protein kinase ATM	0	1	0	1
Rho-associated protein kinase 1	0	0	6	6
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Serine/threonine-protein kinase ATR	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	0	6	6
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	0	6	6
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	6	6
Ephrin type-A receptor 7	0	0	5	5
Delta(24)-sterol reductase	0	0	6	6
Ribosomal protein S6 kinase alpha-1	0	1	6	7
Dual specificity testis-specific protein kinase 1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	0	6	6
Serine/threonine-protein kinase STK11	0	0	6	6
Serine/threonine-protein kinase N1	0	0	6	6
Serine/threonine-protein kinase N2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
Discoidin domain-containing receptor 2	0	1	6	7
AP2-associated protein kinase 1	0	1	6	7
Myosin light chain kinase 3	0	0	6	6
Putative heat shock protein HSP 90-beta 2	0	0	6	6
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	5	5
Serine/threonine-protein kinase ULK3	0	0	6	6
Uncharacterized protein FLJ45252	0	0	6	6
Acyl-CoA dehydrogenase family member 11	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	6	6
Serine/threonine-protein kinase MARK2	0	0	6	6
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	6	6
Myosin-14	0	0	6	6
AarF domain-containing protein kinase 1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
MAP kinase-activated protein kinase 5	0	0	5	5
Misshapen-like kinase 1	0	0	5	5
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	0	1
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
ATP-dependent RNA helicase DDX1	0	0	6	6
Aurora kinase B	0	1	6	7
Serine/threonine-protein kinase Nek1	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	6	6
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Nucleolar GTP-binding protein 1	0	0	6	6
Serine/threonine-protein kinase D2	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	5	5
RNA cytidine acetyltransferase	0	0	6	6
Serine/threonine-protein kinase SIK2	0	0	6	6
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
dCTP pyrophosphatase 1	0	0	6	6
Dual specificity protein kinase CLK4	0	0	6	6
Casein kinase I isoform gamma-1	0	0	6	6
Phenylalanine--tRNA ligase beta subunit	0	0	6	6
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	6	6
Midasin	0	0	6	6
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Mitogen-activated protein kinase kinase kinase 20	0	0	6	6
Cyclin-dependent kinase 12	0	0	6	6
Serine/threonine-protein kinase 26	0	0	6	6
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	7
Serine/threonine-protein kinase TBK1	0	1	6	7
Septin-9	0	0	6	6
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO2	0	0	6	6
Serine/threonine-protein kinase ICK	0	0	5	5
RAC-gamma serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase SIK3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	0	6	6
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
progesterone receptor	15	0	0	15
glucocerebrosidase	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cytochrome P450 1A2	0	4	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Acetylcholinesterase	0	5	0	5
Prostaglandin G/H synthase 1	0	3	0	3
Cannabinoid receptor 2	0	1	0	1
D(2) dopamine receptor	0	0	1	1
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
Lactoperoxidase	0	1	0	1
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 15	0	3	0	4
dopamine D1 receptor	1	0	0	1
pregnane X receptor	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Glucocorticoid receptor	0	14	2	21
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	14	0	14
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Multidrug and toxin extrusion protein 1	0	5	0	5
Chain A, Beta-lactamase	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Progesterone receptor	0	3	0	4
Androgen receptor	0	4	0	4
Androgen receptor	0	6	0	6
Adenosine receptor A1	0	4	0	6
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A2a	0	2	1	6
Mu-type opioid receptor	0	7	2	9
ORF73	0	0	1	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Ileal sodium/bile acid cotransporter	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile acid receptor	0	1	1	2
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Fatty acid-binding protein, liver	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	3	7	15
Albumin	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Translocator protein	0	2	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
5-hydroxytryptamine receptor 1A	0	4	2	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	2	5
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	3	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	9	1	11
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	5	0	5
UDP-glucuronosyltransferase 1A4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	3	2	5
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Cytochrome P450 2J2	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	4	0	5
Solute carrier family 22 member 6	0	2	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
Pantothenate synthetase	0	2	0	2
Cell division cycle 7-related protein kinase	0	0	4	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	5	5
High affinity nerve growth factor receptor	0	0	5	5
Tyrosine-protein kinase Fgr	0	0	5	5
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Dual specificity protein kinase TTK	0	0	5	5
Myosin-10	0	0	4	4
TGF-beta receptor type-2	0	0	5	5
G protein-coupled receptor kinase 6	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
Choline-phosphate cytidylyltransferase A	0	0	4	4
Dual specificity protein kinase CLK3	0	0	5	5
Ras-related protein Rab-27A	0	0	5	5
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Serine/threonine-protein kinase PLK1	0	2	5	7
Casein kinase I isoform gamma-2	0	0	5	5
Cyclin-dependent kinase 17	0	0	5	5
Potassium voltage-gated channel subfamily H member 2	0	8	0	8
Integrin-linked protein kinase	0	0	5	5
Activin receptor type-2B	0	0	5	5
Sodium channel protein type 5 subunit alpha	0	4	0	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	5	5
Serine/threonine-protein kinase N3	0	0	5	5
ATP-dependent RNA helicase DHX30	0	0	5	5
ATP-dependent RNA helicase DDX42	0	0	4	4
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Regulatory-associated protein of mTOR	0	2	0	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	5	5
Serine/threonine-protein kinase Nek7	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	5	5
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
PAS domain-containing serine/threonine-protein kinase	0	0	4	4
Dual specificity testis-specific protein kinase 2	0	0	3	3
Target of rapamycin complex subunit LST8	0	2	0	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase NLK	0	0	5	5
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
Solute carrier family 22 member 1	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
D(2) dopamine receptor	0	3	1	4
D(4) dopamine receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	3	1	4
Kappa-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	5	1	6
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	1	0	1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Cytochrome P450 2C19	0	5	0	5
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	1	0	1
GALC protein	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	3	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	3	0	4
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	2	3	6
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	2	5
Glutamate receptor ionotropic, NMDA 2B	0	2	2	5
Glutamate receptor ionotropic, NMDA 2C	0	2	2	5
Large neutral amino acids transporter small subunit 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	2	2	5
Glutamate receptor ionotropic, NMDA 3B	0	2	2	5
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	2	2	5
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
2-dehydropantoate 2-reductase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Heat shock protein HSP 90-alpha	0	0	1	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	0	1	1
Nitric oxide synthase, brain	0	1	0	1
Cyclin-A1	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 3	0	2	0	2
Gag-Pol polyprotein	0	3	0	3
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Replicase polyprotein 1ab	0	2	0	2
Replicase polyprotein 1ab	0	3	0	3
Cytochrome P450 2D6	0	5	0	5
Gag-Pol polyprotein	0	3	0	3
Alpha-1B adrenergic receptor	0	7	3	10
Substance-K receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	7	3	11
Thromboxane-A synthase	0	3	0	3
Gag-Pol polyprotein	0	2	0	2
Alpha-1A adrenergic receptor	0	7	3	10
Thromboxane-A synthase	0	0	0	2
Genome polyprotein	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Protease	0	3	2	9
Multidrug and toxin extrusion protein 2	0	2	0	2
Protease	0	4	2	6
Protease	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Beta-1 adrenergic receptor	0	1	2	5
beta-2 adrenergic receptor	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Beta-2 adrenergic receptor	0	4	1	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Beta-1 adrenergic receptor	0	5	2	9
Beta-2 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	0	2	1	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
D(1A) dopamine receptor	1	0	0	1
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Capsid protein	0	1	1	2
Cereblon isoform 4	0	3	0	3
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Protein cereblon	0	4	2	9
Zinc finger protein Aiolos	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
Phospholipase A-2-activating protein	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
nonstructural protein 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Valosin-containing protein	0	1	0	1
apical membrane antigen 1, AMA1	2	0	0	2
lysosomal alpha-glucosidase preproprotein	2	0	0	2
microphthalmia-associated transcription factor isoform 9	0	1	0	1
DNA polymerase beta	2	0	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Leukotriene C4 synthase	0	0	2	2
tyrosine-protein kinase Yes	2	0	0	2
Serine/threonine-protein kinase 25	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
NUAK family SNF1-like kinase 1	0	1	2	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	4	4
Serine/threonine-protein kinase 17B	0	0	2	2
Cyclin-dependent kinase 14	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	2	2
Serine/threonine-protein kinase Chk2	0	1	2	3
RAF proto-oncogene serine/threonine-protein kinase	0	1	2	3
Receptor tyrosine-protein kinase erbB-2	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	2	2	4
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Mast/stem cell growth factor receptor Kit	0	4	2	6
Myosin light chain kinase, smooth muscle	0	0	2	2
Insulin receptor-related protein	0	0	2	2
Platelet-derived growth factor receptor alpha	0	3	2	5
Vascular endothelial growth factor receptor 1	0	3	2	5
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Fibroblast growth factor receptor 2	0	1	2	3
Receptor tyrosine-protein kinase erbB-3	0	0	2	2
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
Protein kinase C eta type	0	0	3	3
Activin receptor type-2A	0	0	2	2
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Leukocyte tyrosine kinase receptor	0	0	2	2
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
G protein-coupled receptor kinase 4	0	0	2	2
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	3	2	5
Vascular endothelial growth factor receptor 2	0	4	2	6
Serine/threonine-protein kinase receptor R3	0	0	4	4
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase TXK	0	0	2	2
Tyrosine-protein kinase ZAP-70	0	0	2	2
Cyclin-dependent kinase 8	0	0	2	2
Tyrosine-protein kinase Blk	0	0	2	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	0	2	2
Death-associated protein kinase 1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	2	4
Ephrin type-B receptor 1	0	0	2	2
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Cell division control protein 2 homolog	0	0	2	2
Calcium-dependent protein kinase 1	0	0	2	2
Tubulin alpha-1A chain	0	0	2	2
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Protein kinase C epsilon type	0	1	3	4
Angiopoietin-1 receptor	0	1	2	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	4	4
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	0	3	3
Serine/threonine-protein kinase PAK 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Serine/threonine-protein kinase D1	0	0	3	3
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	0	2	2
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Receptor protein-tyrosine kinase	0	1	0	1
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Rab-like protein 3	0	0	3	3
Serine/threonine-protein kinase Nek5	0	0	2	2
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Cyclin-dependent kinase 15	0	0	2	2
SRSF protein kinase 1	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	1	2	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
Serine/threonine-protein kinase PAK 6	0	1	3	4
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	2	2
Serine/threonine-protein kinase PLK2	0	1	2	3
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	1	2	3
eIF-2-alpha kinase GCN2	0	0	2	2
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
ALK tyrosine kinase receptor	0	1	2	3
SRSF protein kinase 3	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Serine/threonine-protein kinase 24	0	0	4	4
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
cytochrome P450 2C19 precursor	2	0	0	2
ClpP	1	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
Alpha-1A adrenergic receptor	0	0	1	1
5-hydroxytryptamine receptor 4	0	4	0	4
Angiotensin-converting enzyme	0	2	0	2
Alpha-2B adrenergic receptor	0	2	2	6
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 2C	0	4	1	5
5-hydroxytryptamine receptor 2B	0	4	1	5
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Nischarin	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Adenosine receptor A3	0	2	1	3
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	1	1	2
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	3	3	7
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Vasopressin V1a receptor	0	3	1	4
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Flavin reductase (NADPH)	0	0	1	1
alpha-galactosidase	2	0	0	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
Alpha-synuclein	1	2	0	3
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Solute carrier organic anion transporter family member 2B1	0	4	0	4
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Cytochrome P450 3A5	0	1	1	2
ATP-dependent translocase ABCB1	0	1	0	1
Plasmepsin V	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Free fatty acid receptor 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	4	7
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	2	1	3
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	2	0	3
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	2
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Carbonic anhydrase 6	0	1	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Carbonic anhydrase 7	0	1	0	2
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
Carbonic anhydrase 14	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	0	4	4
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Thymidine kinase 2	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Thymidine kinase, cytosolic	0	1	0	1
huntingtin isoform 2	1	0	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Aromatase	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Protein delta homolog 1	0	1	1	2
Cyclin-dependent kinase 10	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
lethal factor (plasmid)	2	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Renin	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A1	0	2	1	5
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
MAP kinase-activated protein kinase 3	0	0	1	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
Carbonic anhydrase	0	0	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
72 kDa type IV collagenase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (269)

Protein Targets (1,424)

Lipomatosis

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (269)

Drugs Studied (145)

Protein Targets (1,424)