Page last updated: 2024-09-28

Tuberculosis, Oral

Tuberculosis of the mouth, tongue, and salivary glands.

Synonyms(1)

Synonym
Tuberculosis, Oral

Research

Studies (51)

TimeframeStudies, This Condition (%)All Conditions %
pre-199017 (33.33)23.3326
1990's9 (17.65)12.5806
2000's9 (17.65)18.1394
2010's13 (25.49)28.8240
2020's3 (5.88)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
pyrazinamide0low120
pyridoxine0low20
clofazimine0low10
isoniazid0low190
ofloxacin0low10
aminosalicylic acid0low10
thalidomide0low10
prednisolone0low10
ethambutol0low100
streptomycin0low70
technetium0low10
methotrexate0low40
inositol 3-phosphate0low30
amphotericin b0low10
opc-676830low10
mocetinostat0low10
jaw0low20
sodium pertechnetate tc 99m0low20
technetium tc 99m medronate0low10
exudates0low10
rifampin0low180

Protein Targets (350)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, 2-oxoglutarate Oxygenase6006
Microtubule-associated protein tau3003
thioredoxin glutathione reductase3003
Smad32002
euchromatic histone-lysine N-methyltransferase 29009
microphthalmia-associated transcription factor isoform 90101
Carbonic anhydrase 10202
Carbonic anhydrase 20213
Tyrosine-protein phosphatase non-receptor type 10011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, Cruzipain2002
interleukin 82002
phosphopantetheinyl transferase4004
GLS protein2002
glucocorticoid receptor [Homo sapiens]7007
farnesoid X nuclear receptor4004
peroxisome proliferator-activated receptor delta5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA4004
nuclear factor erythroid 2-related factor 2 isoform 15005
peripheral myelin protein 223003
lamin isoform A-delta103003
Cytochrome P450 1A20303
Cytochrome P450 3A40404
Cytochrome P450 2D60303
Cytochrome P450 2C9 0303
Cytochrome P450 2C190404
Nuclear receptor ROR-gamma1001
Potassium voltage-gated channel subfamily H member 20404
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
GLI family zinc finger 36006
AR protein8008
nuclear receptor subfamily 1, group I, member 34004
retinoid X nuclear receptor alpha5005
pregnane X nuclear receptor4004
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0101
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40809
5-hydroxytryptamine receptor 40202
Bile salt export pump011011
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M10215
Muscarinic acetylcholine receptor M30215
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M10216
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30215
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor1002
5-hydroxytryptamine receptor 70101
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
Canalicular multispecific organic anion transporter 10808
Chain A, JmjC domain-containing histone demethylation protein 3A2002
USP1 protein, partial3003
TDP1 protein6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
cytochrome P450 family 3 subfamily A polypeptide 46006
estrogen nuclear receptor alpha8008
G2002
cytochrome P450 2D63003
67.9K protein4004
cytochrome P450 2D6 isoform 12002
chromobox protein homolog 13003
potassium voltage-gated channel subfamily H member 2 isoform d2002
transcriptional regulator ERG isoform 32002
thyroid hormone receptor beta isoform 24004
importin subunit beta-1 isoform 12002
mitogen-activated protein kinase 11001
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
eyes absent homolog 2 isoform a1001
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
geminin5005
streptokinase A precursor0022
mitogen-activated protein kinase kinase kinase 3 isoform 10011
Interferon beta3003
HLA class I histocompatibility antigen, B alpha chain 2002
Estrogen receptor0011
ATP-dependent translocase ABCB10101
Spike glycoprotein0011
5-hydroxytryptamine receptor 1A0011
Cruzipain0101
Spike glycoprotein2002
C-terminal-binding protein 11001
Estrogen receptor beta0011
Inositol hexakisphosphate kinase 12002
cytochrome P450 2C9, partial2002
Chain A, Beta-lactamase1001
acetylcholinesterase1001
glp-1 receptor, partial1001
thioredoxin reductase4004
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma5005
SMAD family member 21001
ATAD5 protein, partial4004
SMAD family member 31001
apical membrane antigen 1, AMA11001
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)3003
progesterone receptor3003
retinoic acid nuclear receptor alpha variant 13003
estrogen-related nuclear receptor alpha4004
peroxisome proliferator activated receptor gamma3003
caspase-31001
IDH12002
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
thyroid stimulating hormone receptor1001
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x2002
thyroid hormone receptor beta isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 24004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
heat shock protein beta-11001
DNA polymerase iota isoform a (long)2002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Vpr1001
Voltage-dependent calcium channel gamma-2 subunit3003
Rap guanine nucleotide exchange factor 31001
Cellular tumor antigen p533003
Glutamate receptor 23003
Glutathione S-transferase omega-10202
TAR DNA-binding protein 432002
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Enoyl-[acyl-carrier-protein] reductase [NADH]0206
Pantothenate synthetase0202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Luciferase1001
EWS/FLI fusion protein5005
bromodomain adjacent to zinc finger domain 2B1001
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
nuclear receptor ROR-gamma isoform 11001
cytochrome P450 3A4 isoform 11001
histone acetyltransferase KAT2A isoform 13003
Gamma-aminobutyric acid receptor subunit pi1102
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20101
Bile salt export pump0606
Myeloperoxidase0101
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0203
DNA gyrase subunit B0203
Cytochrome P450 2C80202
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Gamma-aminobutyric acid receptor subunit beta-11102
Gamma-aminobutyric acid receptor subunit delta1102
Gamma-aminobutyric acid receptor subunit gamma-21102
Gamma-aminobutyric acid receptor subunit alpha-51102
Gamma-aminobutyric acid receptor subunit alpha-31102
Gamma-aminobutyric acid receptor subunit gamma-11102
Gamma-aminobutyric acid receptor subunit alpha-21102
Gamma-aminobutyric acid receptor subunit alpha-41102
Gamma-aminobutyric acid receptor subunit gamma-31102
Gamma-aminobutyric acid receptor subunit alpha-61102
Gamma-aminobutyric acid receptor subunit alpha-11102
Gamma-aminobutyric acid receptor subunit beta-31102
Gamma-aminobutyric acid receptor subunit beta-21102
Endonuclease III-like protein 10101
DNA gyrase subunit B0304
DNA gyrase subunit A0304
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
GABA theta subunit1102
Endonuclease 8-like 10101
Gamma-aminobutyric acid receptor subunit epsilon1102
Chymotrypsinogen A0101
ATP-dependent phosphofructokinase2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, Ferritin light chain2002
acid sphingomyelinase1001
dopamine D1 receptor2002
ClpP1001
15-lipoxygenase, partial2002
aldehyde dehydrogenase 1 family, member A16006
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 12002
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
flap endonuclease 12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA polymerase kappa isoform 11001
survival motor neuron protein isoform d1001
M-phase phosphoprotein 81001
muscleblind-like protein 1 isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Integrin beta-31001
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30204
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40303
PPM1D protein1001
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Histone deacetylase 40101
Histone deacetylase 10202
Histone deacetylase 70101
Histone deacetylase 20202
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
arylsulfatase A3003
STE240001
CAAX prenyl protease0001
Trypsin0001
Albumin0022
Cytochrome P450 2B60112
luciferase0001
nuclear receptor subfamily 1, group I, member 21001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
thyroid stimulating hormone receptor2002
NAD-dependent protein deacetylase sirtuin-60101
Pyridoxal kinase0001
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Solute carrier organic anion transporter family member 1A40101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
60 kDa heat shock protein, mitochondrial0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
10 kDa heat shock protein, mitochondrial0101
DNA-directed RNA polymerase subunit beta0101
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Solute carrier organic anion transporter family member 1B10203
Cereblon isoform 40202
Prostaglandin G/H synthase 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]