Reflex Sympathetic Dystrophy

A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)

Synonym
Reflex Sympathetic Dystrophy

Excerpt	Reference
"Reflex sympathetic dystrophy is a syndrome of burning pain, hyperesthesia, swelling, hyperhidrosis, and trophic changes in the skin and bone of the affected extremity."	( McLellan, TL; Schwartzman, RJ, 1987)
"Reflex sympathetic dystrophy is an automatic dysfunction that occasionally complicates healing after trauma or surgery."	( Piepgrass, W; Rohrich, RJ; Stevenson, TR, 1987)
"The diagnosis of reflex sympathetic dystrophy is based on clinical presentation and often the presence of a positive three-phase technetium bone scan result."	( Koman, LA; Poehling, GG; Pollock, FE; Smith, BP, 1993)
"Reflex sympathetic dystrophy is known since the XVIIIth century."	( Boralevi, F; Jouary, T; Léauté-Labrèze, C; Pillet, P; Taieb, A, 2002)
"Reflex sympathetic dystrophy is a complex disease, however its physiopathology is now understood."	( Boralevi, F; Jouary, T; Léauté-Labrèze, C; Pillet, P; Taieb, A, 2002)
"Reflex sympathetic dystrophy is a major complication following surgical treatment of fractures of the distal radius."	( Cazeneuve, JF; Hassan, Y; Kermad, K; Leborgne, JM, 2002)
"Reflex sympathetic dystrophy is a disease clinically characterized severe pain, allodynia (severe pain caused by a touch) and over-reaction of pain sensation after a minor injury."	( Hayashi, Y, 2008)

Excerpt	Reference
"Patients with reflex sympathetic dystrophy have posttraumatic pain disproportionate to the injury and spreading beyond the distribution of any single peripheral nerve."	( Goldstein, DS; Li, ST; Tack, C, 2000)

Excerpt	Reference
"These results confirm the efficacy of treating reflex sympathetic dystrophy with calcitonin and calcium and the superiority of this treatment as compared with nonsteroidal anti-inflammatory drugs."	( Diaz, P; Espinos, D; Gomez-Castresana, F; Merono, E; Rico, H; Torrubiano, J, 1987)
"A case of longstanding, previously untreated reflex sympathetic dystrophy secondary to a minor injury is presented."	( Piepgrass, W; Rohrich, RJ; Stevenson, TR, 1987)
"A comparative study of three treatments of reflex sympathetic dystrophy (selected at random) was carried out on 55 cases : 20 patients were treated with calcitonin, 19 with beta-blocking agents, and 16 with griseofulvin."	( Breuillard, P; Friez, L; Meignan, S; Pere, G, 1982)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	467 (44.56)	23.3326
1990's	273 (26.05)	12.5806
2000's	194 (18.51)	18.1394
2010's	99 (9.45)	28.8240
2020's	15 (1.43)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	25	5
adenine	low	1	0
ammonium hydroxide	low	1	0
creatine	low	1	0
lactic acid	low	2	0
dimethyl sulfoxide	medium	12	5
histamine	low	1	0
iodine	medium	3	1
dihydroxyphenylalanine	low	1	0
thioctic acid	low	1	0
inositol	low	1	0
niacinamide	low	1	0
niacin	low	1	0
phenol	medium	2	1
pyrazinamide	low	1	0
pyridoxine	medium	4	1
taurine	low	1	0
thiamine	medium	5	1
uric acid	low	5	0
1,3-dipropyl-8-cyclopentylxanthine	low	1	0
phenytoin	low	2	0
acetaminophen	medium	6	2
alendronate	medium	3	2
theophylline	low	1	0
amitriptyline	medium	10	1
amobarbital	medium	1	1
antipyrine	low	2	0
aspirin	medium	8	1
azepexole	low	1	0
baclofen	medium	7	1
bamethan	low	2	0
bretylium	medium	6	1
buflomedil	medium	1	1
bupivacaine	medium	33	4
butalbital	low	1	0
caffeine	low	4	0
carbamazepine	low	3	0
celecoxib	low	1	0
chlormezanone	low	1	0
chlorpromazine	low	7	0
chlorpyrifos	low	1	0
chlorthalidone	low	1	0
clomipramine	medium	2	1
clonidine	medium	11	1
desipramine	low	1	0
diazepam	low	5	0
diclofenac	medium	3	1
pentetic acid	low	2	0
dimethoate	low	1	0
diphenhydramine	low	1	0
droperidol	medium	1	1
9-(2-hydroxy-3-nonyl)adenine	low	1	0
etidronate	low	5	0
fentanyl	low	4	0
fluorouracil	low	1	0
fluoxetine	low	1	0
gabapentin	medium	23	5
glafenine	medium	1	1
guanethidine	medium	64	11
lidocaine	medium	45	10
indomethacin	low	6	0
iproniazid	low	1	0
isoniazid	low	12	0
2-propanol	low	2	0
ketamine	medium	23	5
ketanserin	medium	2	2
ketorolac	low	3	0
labetalol	low	1	0
memantine	medium	1	1
meperidine	low	2	0
mephenesin	low	1	0
mepivacaine	medium	1	1
meprobamate	low	1	0
methadone	low	2	0
metoprolol	low	1	0
nafronyl	medium	2	1
nifedipine	low	5	0
nimesulide	low	1	0
nitroglycerin	low	4	0
orphenadrine	low	2	0
oxyphenbutazone	medium	5	1
pamidronate	medium	17	6
pentoxifylline	low	1	0
phenindione	low	1	0
phenobarbital	medium	23	1
phenoxybenzamine	low	7	0
phenylbutazone	low	7	0
pindolol	medium	1	1
piracetam	low	1	0
prilocaine	medium	5	3
procaine	low	15	0
promethazine	low	5	0
propofol	low	1	0
propranolol	medium	5	1
sarpogrelate	medium	1	1
thalidomide	medium	3	1
tizanidine	low	1	0
tolmetin	medium	3	1
trazodone	low	1	0
xylazine	low	1	0
prednisolone	medium	12	3
reserpine	medium	12	2
phentolamine	medium	9	2
hydroxyproline	low	5	0
thyroxine	low	1	0
dextroamphetamine	low	1	0
aldosterone	low	1	0
prednisone	medium	17	1
methylprednisolone acetate	low	1	0
aspartic acid	medium	2	1
lysine	low	1	0
apomorphine	low	1	0
aminopyrine	low	2	0
methyltestosterone	low	1	0
carbostyril	low	1	0
phenylephrine	low	1	0
bretylium tosylate	low	2	0
methionine	low	1	0
cycloserine	low	3	0
mannitol	medium	9	3
tert-butylhydroperoxide	low	1	0
triamcinolone acetonide	low	1	0
methylprednisolone	medium	17	3
isosorbide dinitrate	low	1	0
phenothiazine	low	1	0
ergotamine	low	3	0
meglumine	low	1	0
citronellol	low	1	0
isoxazoles	low	1	0
thiazoles	low	1	0
benactyzine	low	1	0
betamethasone	low	4	0
nandrolone	low	1	0
ninhydrin	medium	1	1
dihydroergotamine	low	2	0
methoxyhydroxyphenylglycol	low	1	0
pentamethonium	medium	1	1
malondialdehyde	low	1	0
trimecaine	low	1	0
acetylcysteine	medium	6	2
ethambutol	low	1	0
durapatite	low	1	0
vancomycin	low	1	0
methylprednisolone hemisuccinate	low	1	0
streptomycin	low	1	0
n-methylaspartate	low	1	0
trimethaphan	low	1	0
technetium	low	30	0
gadolinium	low	3	0
magnesium sulfate	medium	2	1
calcium sulfate	low	1	0
trolamine salicylate	medium	67	2
clodronic acid	medium	4	1
phenyl acetate	medium	13	1
triamcinolone	low	4	0
tramadol	low	3	0
oxcarbazepine	low	1	0
substance p	low	7	0
fomesafen	medium	44	2
aripiprazole	low	1	0
duloxetine hydrochloride	low	1	0
ibandronic acid	medium	1	1
3-iodobenzylguanidine	low	1	0
adenosine	low	2	0
n-acetylaspartic acid	low	1	0
cephalosporin c	low	1	0
triazoles	low	2	0
delphinidin	medium	1	1
fluorodeoxyglucose f18	low	1	0
6-amino-1-hydroxyhexane-1,1-diphosphonate	medium	1	1
voriconazole	low	1	0
fibrinogen	low	1	0
3,4-dihydroxyphenylglycol	low	1	0
homocysteine	low	1	0
acetylsalicylic acid lysinate	low	1	0
n-hydroxysuccinimide suberic acid ester	medium	1	1
pyridinoline	low	1	0
deoxypyridinoline	low	1	0
parecoxib	low	1	0
imatinib mesylate	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	7	0
technetium tc 99m etidronate	low	3	0
3-(2,2,2-trimethylhydrazine)propionate	low	1	0
4-iodoamphetamine	medium	1	1
ganglerone	low	1	0
levofloxacin	low	1	0
naproxen	low	3	0
clorazepate dipotassium	medium	1	1
angiotensin ii	low	1	0
atropine	low	4	0
ropivacaine	low	4	0
zm 241385	low	1	0
lenalidomide	medium	1	1
cortisone	low	11	0
benzofurans	low	1	0
bradykinin	low	2	0
strychnine	low	1	0
griseofulvin	medium	14	3
pentazocine	low	1	0
bq 123	low	2	0
betadex	low	1	0
tacrolimus	low	2	0
dipyrone	medium	1	1
pyrophosphate	low	7	0
chlorprothixene	medium	1	1
capsaicin	medium	4	2
ethionamide	low	6	0
alpha-chymotrypsin	low	1	0
dinoprost	low	1	0
calcitriol	low	2	0
rutin	low	4	0
anandamide	low	1	0
8-epi-prostaglandin f2alpha	low	1	0
4-hydroxy-2-nonenal	low	1	0
codeine	low	2	0
phenylephrine hydrochloride	low	1	0
hydrocodone	low	1	0
hydromorphone	low	2	0
naloxone	low	3	0
oxycodone	low	1	0
sirolimus	low	4	0
morphine	medium	21	3
clobetasol	low	1	0
iloprost	low	1	0
tin	low	1	0
arsenic	low	1	0
morphine-6-glucuronide	medium	1	1
gallium	low	1	0
butorphanol	low	1	0
phosphorus	low	4	0
strontium radioisotopes	low	2	0
pregabalin	low	2	0
ammonium sulfate	low	1	0
dihydroergotoxine	low	2	0
echinacin	low	1	0
everolimus	low	2	0
technetium tc 99m pyrophosphate	low	2	0
beta-escin	low	1	0
gadolinium dtpa	low	2	0
phosphocreatine	low	1	0
technetium tc 99m diphosphonate	low	4	0
mocetinostat	low	2	0
psd 502	medium	2	1
perampanel	low	1	0
technetium tc 99m exametazime	low	3	0
scopolamine hydrobromide	low	1	0
ent-dextilidine	low	1	0
acid phosphatase	low	2	0
calcitonin	medium	5	1
(4-24)-ply(a)	medium	1	1
neuropeptide y	low	2	0
irl 1620	low	1	0
ziconotide	low	2	0
endothelin-1	low	5	0
technetium tc 99m sestamibi	low	1	0
ro13-9904	low	1	0
sodium pertechnetate tc 99m	low	1	0
cardiovascular agents	low	3	0
piperidines	medium	6	1
vasoactive intestinal peptide	low	3	0
ascorbic acid	medium	12	5
salicylates	low	2	0
mobic	low	1	0
warfarin	low	2	0
hyaluronoglucosaminidase	low	1	0
vitamin b 12	low	3	0
cyclosporine	low	5	0
technetium tc 99m medronate	medium	57	2
deoxyguanosine	low	1	0
rifampin	low	1	0
pralidoxime	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
eye	low	2	0
ego	low	1	0

Protein Targets (1,724)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	17	0	0	17
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	48	0	0	48
USP1 protein, partial	40	0	0	40
TDP1 protein	69	0	0	69
vitamin D3 receptor isoform VDRA	24	0	0	24
importin subunit beta-1 isoform 1	8	0	0	8
flap endonuclease 1	12	0	0	12
serine/threonine-protein kinase PLK1	5	0	0	5
snurportin-1	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	25	0	0	25
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
geminin	69	0	0	69
DNA polymerase kappa isoform 1	19	0	0	19
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	1	2	6
Fatty acid-binding protein, intestinal	0	3	2	5
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	2	2	4
Cyclin-dependent kinase 2	0	1	3	4
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	9	0	0	9
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	2	3
Mitogen-activated protein kinase 14	0	3	2	5
ATAD5 protein, partial	24	0	0	24
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	18	0	0	18
thyroid stimulating hormone receptor	36	0	0	36
estrogen-related nuclear receptor alpha	65	0	0	65
67.9K protein	14	0	0	14
euchromatic histone-lysine N-methyltransferase 2	78	0	0	78
peripheral myelin protein 22 isoform 1	12	0	0	12
chromobox protein homolog 1	45	0	0	45
nuclear factor erythroid 2-related factor 2 isoform 2	25	0	0	25
nuclear receptor ROR-gamma isoform 1	24	0	0	24
muscarinic acetylcholine receptor M1	28	0	0	28
lamin isoform A-delta10	63	0	0	63
5-hydroxytryptamine receptor 1A	0	10	5	15
Adenosine receptor A3	0	13	3	17
Adenosine receptor A1	0	12	2	20
Adenosine receptor A1	0	3	0	3
Adenosine receptor A3	0	6	0	7
Adenosine receptor A2a	0	11	9	25
Adenosine receptor A2b	0	7	2	14
Adenosine receptor A2b	0	5	2	11
Adenosine receptor A1	0	11	7	23
Adenosine receptor A2a	0	11	4	24
Vasopressin V2 receptor	0	0	0	3
Mu-type opioid receptor	0	29	13	46
Adenosine receptor A1	0	3	1	4
Adenylate cyclase type 5	0	2	0	3
Adenylate cyclase type 1	0	0	0	3
Sigma non-opioid intracellular receptor 1	0	8	1	9
hypoxia-inducible factor 1 alpha subunit	16	0	0	16
RAR-related orphan receptor gamma	64	0	0	64
GLI family zinc finger 3	65	0	0	65
AR protein	85	0	0	85
aldehyde dehydrogenase 1 family, member A1	44	0	0	44
retinoic acid nuclear receptor alpha variant 1	60	0	0	60
retinoid X nuclear receptor alpha	42	0	0	42
estrogen nuclear receptor alpha	93	0	0	93
peroxisome proliferator-activated receptor delta	39	0	0	39
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
activating transcription factor 6	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	33	0	0	33
Histone H2A.x	24	0	0	24
thyroid hormone receptor beta isoform a	25	0	0	25
heat shock protein beta-1	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 1	60	0	0	60
Voltage-dependent calcium channel gamma-2 subunit	32	0	0	32
Glutamate receptor 2	35	1	1	37
Gamma-butyrobetaine dioxygenase	0	2	0	2
dopamine D1 receptor	9	0	0	9
GLS protein	33	0	0	33
Thrombopoietin	10	0	0	10
cytochrome P450 2D6 isoform 1	20	0	0	20
cytochrome P450 2C19 precursor	10	0	0	10
ras-related protein Rab-9A	9	0	0	9
histone acetyltransferase KAT2A isoform 1	24	0	0	24
lethal factor (plasmid)	14	0	0	14
POU domain, class 2, transcription factor 1	0	0	0	2
Spike glycoprotein	35	2	3	40
ATP-dependent phosphofructokinase	31	0	0	31
Microtubule-associated protein tau	29	0	0	29
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Geranylgeranyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	8	0	8
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Adenosine deaminase	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	6	0	6
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
Smad3	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	38	0	0	38
progesterone receptor	39	0	0	39
EWS/FLI fusion protein	32	0	0	32
peroxisome proliferator activated receptor gamma	38	0	0	38
aryl hydrocarbon receptor	25	0	0	25
thyroid hormone receptor beta isoform 2	49	0	0	49
peripheral myelin protein 22	38	0	0	38
cytochrome P450 3A4 isoform 1	34	0	0	34
Gamma-aminobutyric acid receptor subunit pi	34	7	4	45
ATP-binding cassette sub-family C member 3	0	59	0	59
Multidrug resistance-associated protein 4	0	59	0	59
Solute carrier family 22 member 6	0	6	0	6
Carbonic anhydrase 12	0	5	0	8
UDP-glucuronosyltransferase 1A9	0	1	0	4
Bile salt export pump	0	14	0	14
Bile salt export pump	0	93	0	93
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	15	0	19
Carbonic anhydrase 2	0	16	0	21
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	5	1	8
Prostaglandin G/H synthase 1	0	11	0	12
Carbonic anhydrase 3	0	5	0	7
Cytochrome P450 3A4	0	19	1	22
Cytochrome P450 2D6	0	16	1	18
Cytochrome P450 2C9	0	23	1	26
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Gamma-aminobutyric acid receptor subunit beta-1	34	7	4	45
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	34	7	4	45
Gamma-aminobutyric acid receptor subunit gamma-2	34	7	6	47
UDP-glucuronosyltransferase 1-6	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	34	7	4	45
Gamma-aminobutyric acid receptor subunit alpha-3	34	7	4	45
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	5
Carbonic anhydrase 4	0	6	0	9
Prostaglandin G/H synthase 1	0	16	0	17
Carbonic anhydrase 6	0	7	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	34	7	4	45
Gamma-aminobutyric acid receptor subunit alpha-2	34	7	4	45
Gamma-aminobutyric acid receptor subunit alpha-4	34	7	4	45
Gamma-aminobutyric acid receptor subunit gamma-3	34	7	4	45
Gamma-aminobutyric acid receptor subunit alpha-6	34	7	4	45
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
Prostaglandin G/H synthase 2	0	16	2	20
Carbonic anhydrase 7	0	6	0	9
Nuclear receptor ROR-gamma	15	0	0	15
Cytochrome P450 2J2	0	15	0	15
Gamma-aminobutyric acid receptor subunit alpha-1	34	9	6	49
Gamma-aminobutyric acid receptor subunit beta-3	34	7	4	45
Gamma-aminobutyric acid receptor subunit beta-2	34	7	6	47
Carbonic anhydrase 9	0	8	0	11
GABA theta subunit	34	7	4	45
Canalicular multispecific organic anion transporter 1	0	56	0	56
Carbonic anhydrase 15	0	3	0	5
Carbonic anhydrase 13	0	3	0	6
Gamma-aminobutyric acid receptor subunit epsilon	34	7	4	45
Carbonic anhydrase 14	0	5	0	8
Carbonic anhydrase 5B, mitochondrial	0	5	0	8
toxin B	0	0	0	1
Chain A, 2-oxoglutarate Oxygenase	25	0	0	25
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
acetylcholinesterase	24	0	0	24
15-lipoxygenase, partial	13	0	0	13
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	27	0	0	27
NFKB1 protein, partial	10	0	0	10
regulator of G-protein signaling 4	26	0	0	26
glucocorticoid receptor [Homo sapiens]	69	0	0	69
farnesoid X nuclear receptor	29	0	0	29
vitamin D (1,25- dihydroxyvitamin D3) receptor	39	0	0	39
arylsulfatase A	28	0	0	28
Bloom syndrome protein isoform 1	26	0	0	26
D(1A) dopamine receptor	19	0	0	19
survival motor neuron protein isoform d	17	0	0	17
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	6	0	6
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Ataxin-2	34	0	0	34
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	38	0	0	38
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	50	0	0	50
pregnane X nuclear receptor	51	0	0	51
tumor susceptibility gene 101 protein	1	0	0	1
Cyclin-dependent kinase 1	0	1	2	3
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	5	0	5
TAR DNA-binding protein 43	14	0	0	14
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	22	0	0	22
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	1	1
IDH1	24	0	0	24
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
mitogen-activated protein kinase 1	26	0	0	26
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	8	2	10
Phosphoglycerate kinase 1	0	1	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	2	3
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	2	3
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	2	3
Inosine-5'-monophosphate dehydrogenase 2	0	1	2	3
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine kinase	0	0	2	3
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	0	3	3	6
Androgen receptor	0	8	0	8
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	3
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Acetylcholinesterase	0	9	0	9
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
interleukin 8	9	0	0	9
estrogen receptor 2 (ER beta)	33	0	0	33
transcriptional regulator ERG isoform 3	7	0	0	7
Polyphenol oxidase 2	0	6	0	9
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	46	0	0	46
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	3
Chain A, Ferritin light chain	10	0	0	10
Luciferase	26	0	0	26
G	24	0	0	24
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	22	0	0	22
histone deacetylase 9 isoform 3	5	0	0	5
Interferon beta	31	0	0	31
HLA class I histocompatibility antigen, B alpha chain	24	0	0	24
Nicotinate phosphoribosyltransferase	0	6	0	6
Inositol hexakisphosphate kinase 1	24	0	0	24
cytochrome P450 2C9, partial	24	0	0	24
ORF73	0	0	3	3
Chain A, HADH2 protein	25	0	0	25
Chain B, HADH2 protein	25	0	0	25
cytochrome P450 2D6	39	0	0	39
atrial natriuretic peptide receptor 2 precursor	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	11	0	0	11
Solute carrier family 22 member 1	0	29	0	35
Polyunsaturated fatty acid lipoxygenase ALOX15B	13	0	0	13
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
5-hydroxytryptamine receptor 4	0	34	1	35
Albumin	0	0	7	7
High affinity nerve growth factor receptor	0	1	4	5
Aldo-keto reductase family 1 member B1	0	23	0	23
Muscarinic acetylcholine receptor M2	0	16	2	22
Muscarinic acetylcholine receptor M4	0	18	1	22
Muscarinic acetylcholine receptor M1	0	8	2	12
Muscarinic acetylcholine receptor M3	0	7	2	11
Muscarinic acetylcholine receptor M4	0	7	2	11
5-hydroxytryptamine receptor 2C	0	12	2	14
Muscarinic acetylcholine receptor M5	0	7	2	11
Muscarinic acetylcholine receptor M5	0	19	1	23
Alpha-2A adrenergic receptor	0	29	8	40
Muscarinic acetylcholine receptor M2	0	8	3	14
Muscarinic acetylcholine receptor M1	0	19	2	25
Angiotensin-converting enzyme	0	14	0	14
D(2) dopamine receptor	0	24	5	32
5-hydroxytryptamine receptor 2A	0	15	2	17
Alpha-2B adrenergic receptor	0	28	4	35
Alpha-2C adrenergic receptor	0	26	7	36
5-hydroxytryptamine receptor 1A	0	33	4	38
Muscarinic acetylcholine receptor M3	0	19	2	24
D(1A) dopamine receptor	0	21	3	27
D(1B) dopamine receptor	0	6	0	8
UDP-glucuronosyltransferase 1A4	0	1	0	4
Sodium-dependent noradrenaline transporter	0	29	3	32
Histamine H2 receptor	0	11	2	13
Alpha-1D adrenergic receptor	0	26	5	33
5-hydroxytryptamine receptor 2A	0	33	2	37
5-hydroxytryptamine receptor 2C	0	39	1	41
5-hydroxytryptamine receptor 1B	0	27	1	28
5-hydroxytryptamine receptor 1D	0	6	1	7
5-hydroxytryptamine receptor 1F	0	6	1	7
5-hydroxytryptamine receptor 2B	0	11	2	13
5-hydroxytryptamine receptor 6	0	4	1	5
Histamine H1 receptor	0	5	1	6
Sodium-dependent serotonin transporter	0	24	3	27
5-hydroxytryptamine receptor 7	0	9	1	10
5-hydroxytryptamine receptor 5A	0	4	1	5
5-hydroxytryptamine receptor 5B	0	4	1	5
Histamine H1 receptor	0	25	2	27
D(3) dopamine receptor	0	22	2	26
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	7	0	9
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 3A	0	4	1	5
5-hydroxytryptamine receptor 2B	0	31	1	33
Alpha-1A adrenergic receptor	0	28	6	34
Histamine H2 receptor	23	3	1	32
D(1A) dopamine receptor	6	0	0	6
5-hydroxytryptamine receptor 6	0	21	1	22
5-hydroxytryptamine receptor 7	0	16	0	16
Voltage-dependent N-type calcium channel subunit alpha-1B	0	5	0	5
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Sodium-dependent dopamine transporter	0	20	2	22
Potassium voltage-gated channel subfamily H member 2	0	36	0	36
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	11
Sodium channel protein type 5 subunit alpha	0	9	0	9
Sodium channel protein type 9 subunit alpha	0	7	0	7
5-hydroxytryptamine receptor 4	0	4	1	5
Nuclear receptor subfamily 3 group C member 3	0	14	0	14
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	28	1	29
5-hydroxytryptamine receptor 3B	0	4	1	5
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	7	2	9
Sodium channel protein type 10 subunit alpha	0	3	0	3
Fatty-acid amide hydrolase 1	0	3	0	3
Fatty-acid amide hydrolase 1	0	0	0	1
Potassium channel subfamily K member 3	0	5	0	5
Fatty acid-binding protein, liver	0	1	0	1
Glutamate receptor 1	4	1	1	6
Glutamate receptor 3	4	1	1	6
Glutamate receptor 4	4	1	1	6
Cannabinoid receptor 1	0	4	0	5
Cannabinoid receptor 2	0	2	0	3
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
Fatty-acid amide hydrolase 1	0	5	0	6
Corticotropin-releasing factor receptor 2	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	0	3
Potassium channel subfamily K member 2	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	3	2	8
Cannabinoid receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
glucocerebrosidase	8	0	0	8
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
Chain A, Putative fructose-1,6-bisphosphate aldolase	12	0	0	12
thyroid stimulating hormone receptor	21	0	0	21
cellular tumor antigen p53 isoform a	9	0	0	9
cytochrome P450 2C9 precursor	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	27	0	0	27
Integrin beta-3	5	1	0	6
Integrin alpha-IIb	5	1	0	6
Tryptophan 5-hydroxylase 1	0	2	0	2
Alpha-1B adrenergic receptor	0	24	5	29
D	0	8	0	8
D(3) dopamine receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	12	6	18
D(2) dopamine receptor	0	3	0	3
D(4) dopamine receptor	0	8	1	11
Alpha-2C adrenergic receptor	0	12	6	18
Alpha-2A adrenergic receptor	0	12	6	18
Alpha-1D adrenergic receptor	0	17	5	23
D(1B) dopamine receptor	0	5	0	5
D(4) dopamine receptor	0	6	1	7
D(2) dopamine receptor	0	12	4	17
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	1	0	1
D	0	3	0	3
5-hydroxytryptamine receptor 3E	0	2	0	2
SMAD family member 2	19	0	0	19
Fumarate hydratase	7	0	0	7
PPM1D protein	8	0	0	8
SMAD family member 3	19	0	0	19
polyprotein	7	0	0	7
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
lysosomal alpha-glucosidase preproprotein	5	0	0	5
mu-type opioid receptor isoform MOR-1	0	0	3	3
5-hydroxytryptamine receptor 2A	0	0	3	3
neuropeptide S receptor isoform A	5	0	0	5
Solute carrier family 22 member 2	0	5	0	8
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 3B	0	2	0	2
ATP-dependent translocase ABCB1	0	18	0	23
Neuronal acetylcholine receptor subunit alpha-4	3	3	0	6
Neuronal acetylcholine receptor subunit beta-2	3	3	0	6
Histamine H1 receptor	0	4	3	8
5-hydroxytryptamine receptor 7	0	4	1	5
Alpha-1A adrenergic receptor	0	7	7	16
Alpha-1B adrenergic receptor	0	5	6	13
5-hydroxytryptamine receptor 3A	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Inositol monophosphatase 1	10	0	0	10
5-hydroxytryptamine receptor 3D	0	2	0	2
Multidrug and toxin extrusion protein 2	0	3	0	3
5-hydroxytryptamine receptor 3C	0	2	0	2
Multidrug and toxin extrusion protein 1	0	10	0	10
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	6	0	0	6
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	4
Glutamate receptor ionotropic, NMDA 1	0	9	2	14
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	9	2	14
Glutamate receptor ionotropic, NMDA 2B	0	9	2	14
Glutamate receptor ionotropic, NMDA 2C	0	9	2	14
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	9	2	14
Glutamate receptor ionotropic, NMDA 3B	0	9	2	14
Carbonic anhydrase 4	0	3	0	5
Glutamate receptor ionotropic, NMDA 3A	0	9	2	14
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	4	0	0	4
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	6	0	7
Prostaglandin G/H synthase 2	0	4	0	5
Fatty acid-binding protein, liver	0	6	1	7
Myeloperoxidase	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	9	0	9
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	2	5
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	9	0	0	9
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	16	2	23
Glycine receptor subunit alpha-1	0	17	0	17
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Multidrug resistance-associated protein 6	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Endothelin receptor type B	0	1	0	1
Endothelin-1 receptor	0	3	1	5
Endothelin-1 receptor	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Angiotensin-converting enzyme	0	1	0	2
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
M-phase phosphoprotein 8	16	0	0	16
C-8 sterol isomerase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	3	4	7
Potassium channel subfamily K member 9	0	1	0	1
Delta-type opioid receptor	0	19	7	30
Kappa-type opioid receptor	0	21	9	35
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Cholinesterase	0	4	0	4
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	5	3	8
Replicase polyprotein 1ab	0	6	3	9
Amine oxidase [flavin-containing] A	0	6	0	6
Amine oxidase [flavin-containing] B	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
Serine/threonine-protein kinase mTOR	0	4	2	6
Adenosine receptor A2a	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	4	1	5
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	7
Guanine deaminase	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	18	0	0	18
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	3	1	4
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Cytochrome P450 2C19	0	7	0	7
Kappa-type opioid receptor	0	10	2	13
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	2	0	2
Vitamin D3 receptor A	0	0	2	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Vpr	4	0	0	4
Major prion protein	0	0	3	3
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	6
Cytochrome P450 2B6	0	2	2	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	3	0	4
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	7	0	0	7
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
glp-1 receptor, partial	16	0	0	16
caspase 7, apoptosis-related cysteine protease	11	0	0	11
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
caspase-3	11	0	0	11
thyrotropin-releasing hormone receptor	2	0	0	2
Caspase-7	7	0	0	7
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	2
caspase-3	7	0	0	7
Prostaglandin E synthase	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	3	0	3
Procathepsin L	0	5	3	8
Quinolone resistance protein NorA	0	2	0	3
Beta-3 adrenergic receptor	0	6	5	11
Calpain-2 catalytic subunit	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Sodium-dependent serotonin transporter	0	8	2	10
Delta-type opioid receptor	0	14	3	21
Delta-type opioid receptor	0	12	4	17
Mu-type opioid receptor	0	13	5	21
Bifunctional epoxide hydrolase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	6	0	7
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	15	2	18
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	4	0	5
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	5	0	5
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	7
Carbonic anhydrase	0	1	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	2	0	2
Rap guanine nucleotide exchange factor 4	3	0	0	3
P2Y purinoceptor 12	0	3	0	3
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	4
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	3	3	6
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	2	3	5
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Albumin	0	5	9	15
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	3	2	5
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Sphingomyelin phosphodiesterase	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	4	0	4
Adenylate cyclase type 3	0	2	0	2
Sodium-dependent dopamine transporter	0	11	1	12
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	6	0	6
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	4	0	8
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	2	3
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	6	0	6
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	6	0	6
Glutamate receptor ionotropic, NMDA 2B	0	6	0	6
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	2	3	5
PINK1	1	0	0	1
Parkin	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	15	0	0	15
serine-protein kinase ATM isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Transient receptor potential cation channel subfamily M member 8	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	2	0	2
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Macrophage metalloelastase	0	1	0	1
GALC protein	6	0	0	6
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Trypanothione reductase	0	1	0	1
Envelope glycoprotein	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Beta-1 adrenergic receptor	0	1	4	6
Alpha-1B adrenergic receptor	0	0	4	4
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 3	0	5	0	7
Alpha-1A adrenergic receptor	0	2	4	6
Alpha-2B adrenergic receptor	0	0	0	2
Alpha-2C adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	7	0	8
Nischarin	0	3	0	3
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Kappa-type opioid receptor	0	8	3	13
Mu-type opioid receptor	0	9	3	16
Cytochrome P450 2D4	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	6	6
endonuclease IV	8	0	0	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	5	0	5
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	3	4	0	7
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	2	3
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
huntingtin isoform 2	6	0	0	6
Solute carrier family 22 member 3	0	1	0	1
Histamine H3 receptor	0	1	0	1
Solute carrier family 22 member 2	0	4	0	5
Solute carrier family 22 member 4	0	1	0	1
Transporter	0	5	0	5
Phenylethanolamine N-methyltransferase	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Hsf1 protein	0	0	4	5
Gamma-aminobutyric acid	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	5	11
Translocator protein	0	1	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	5	2	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	4	10
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	6	3	9
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	4	9
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	3	8
Gamma-aminobutyric acid receptor subunit beta-2	0	5	4	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	2	7
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Interleukin-8	0	3	0	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Solute carrier family 22 member 6	0	3	0	5
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
ATP-dependent translocase ABCB1	0	4	0	4
fatty acid synthase	0	1	0	1
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Caspase-7	2	0	0	2
polyadenylate-binding protein 1	0	2	0	2
Cereblon isoform 4	0	5	0	5
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	6	2	11
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	2	3
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	3	1	4
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Prostaglandin D2 receptor	0	1	1	2
Solute carrier family 22 member 7	0	0	0	2
Solute carrier family 22 member 8	0	3	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	2	2	4
N-acetyltransferase Eis	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	1	3	0	4
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Opioid receptor, delta 1b	0	2	0	2
Opioid receptor homologue	0	2	0	2
Proenkephalin-B	0	0	1	1
Kappa-type opioid receptor	0	9	4	14
Mu-type opioid receptor	0	2	0	2
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	2	4
Beta-2 adrenergic receptor	0	10	5	15
Beta-1 adrenergic receptor	0	10	5	15
Thromboxane-A synthase	0	3	0	3
5-hydroxytryptamine receptor 1B	0	5	1	6
5-hydroxytryptamine receptor 5A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	9	0	0	9
apical membrane antigen 1, AMA1	6	0	0	6
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	3
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	3	5
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	3	4
Serine/threonine-protein kinase pim-1	0	0	2	2
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Mitogen-activated protein kinase 1	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	1	2	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	9	0	0	9
hemoglobin subunit beta	2	0	0	2
muscleblind-like protein 1 isoform 1	10	0	0	10
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	1	0	1
Aromatase	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
Cytochrome P450 2C8	0	3	0	4
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
Cytochrome P450 1B1	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Beta-2 adrenergic receptor	0	4	3	9
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	3
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	2
Macrophage migration inhibitory factor	0	3	0	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Prostacyclin receptor	0	1	1	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	2	0	3
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Phospholipase A2, major isoenzyme	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	6
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-1	0	3	0	4
Nitric oxide synthase, inducible	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Aldo-keto reductase family 1 member C3	0	3	0	3
C-X-C chemokine receptor type 3	0	2	0	2
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Aldo-keto reductase family 1 member C1	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	6	0	8
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	3	0	3
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Acetylcholinesterase	0	4	0	4
Cholinesterase	0	2	0	2
Synaptic vesicular amine transporter	0	4	1	5
Vesicular acetylcholine transporter	0	1	0	1
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Heparanase	0	0	1	1
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Zinc finger protein Aiolos	0	0	1	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	2	0	0	2
CAAX prenyl protease 2 isoform 2	0	0	0	1
streptokinase A precursor	0	0	1	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	5
Cationic amino acid transporter 3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Aldehyde oxidase 1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Beta-1 adrenergic receptor	0	4	2	8
Beta-1 adrenergic receptor	0	2	0	2
alpha-galactosidase	4	0	0	4
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	3	3
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	3
Nociceptin receptor	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
tumor necrosis factor	1	0	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
eyes absent homolog 2 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Leukotriene B4 receptor 1	0	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Interstitial collagenase	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Beta-secretase 1	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	2	2	4
bcl-2-related protein A1	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
caspase recruitment domain family, member 15	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
Beta lactamase (plasmid)	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Glutamate receptor 1	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Endolysin	0	0	1	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
rac GTPase-activating protein 1 isoform a	0	1	0	1
ClpP	1	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	2	0	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	4
Angiotensin-converting enzyme	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	2	0	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Genome polyprotein	0	1	0	1
Neuraminidase	0	2	0	2
L-lactate dehydrogenase A chain	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Dipeptidyl peptidase 4	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Protein kinase C zeta type	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Protein-arginine deiminase type-4	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 10	0	0	1	2
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Chain A, Human Adenosine A2A receptor/T4 lysozyme chimera	0	0	1	1
Chain A, Adenosine receptor A2a	0	0	1	1
Chain A, Adenosine receptor A2a	0	0	1	1
Hexokinase-4	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Reflex Sympathetic Dystrophy

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,048)

Protein Targets (1,724)

Reflex Sympathetic Dystrophy

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,048)

Drugs Studied (306)

Protein Targets (1,724)