Page last updated: 2024-09-28

Cattle Plague

A viral disease of cloven-hoofed animals caused by MORBILLIVIRUS. It may be acute, subacute, or chronic with the major lesions characterized by inflammation and ulceration of the entire digestive tract. The disease was declared successfully eradicated worldwide in 2010.

Synonyms(2)

Synonym
Cattle Plague
Rinderpest

Research Excerpts

Overview

ExcerptReference
"Rinderpest, or cattle plague, is caused by Rinderpest virus (RPV), which is related most closely to human Measles virus (MV), both being members of the genus Morbillivirus, a group of viruses known to have strong immunosuppressive effects in vitro and in vivo."( Barrett, T; Cosby, SL; Heaney, J, 2005)

Research

Studies (47)

TimeframeStudies, This Condition (%)All Conditions %
pre-199030 (63.83)23.3326
1990's7 (14.89)12.5806
2000's7 (14.89)18.1394
2010's3 (6.38)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
methane0low10
chlorine0low10
formaldehyde0low10
iodine0low10
phenol0low10
aspirin0low10
diminazene0low10
propiolactone0low10
mefenamic acid0low10
sulfamethazine0low10
sulfapyridine0low10
chloramphenicol0low10
sabinene0low10
streptomycin0low10
magnesium sulfate0low10
cetylpyridinium chloride anhydrous0low10
biotin0low10
glycogen0low10
dienestrol0low10
mtt formazan0low10
bilirubin0low10
phenylephrine hydrochloride0low10
diminazene aceturate0low10
formazans0low10
chlortetracycline0low10
oxytetracycline, anhydrous0low10
agar0low20
eye0low20
concanavalin a0medium11

Protein Targets (395)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase5005
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 83003
thioredoxin reductase3003
GLS protein4004
AR protein120012
aldehyde dehydrogenase 1 family, member A17007
thyroid stimulating hormone receptor3003
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 46006
EWS/FLI fusion protein2002
glucocorticoid receptor [Homo sapiens]4004
retinoic acid nuclear receptor alpha variant 17007
estrogen-related nuclear receptor alpha7007
estrogen nuclear receptor alpha110011
cytochrome P450 2D66006
glucocerebrosidase1001
peroxisome proliferator-activated receptor delta6006
Rac1 protein0011
IDH12002
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
euchromatic histone-lysine N-methyltransferase 27007
Bloom syndrome protein isoform 12002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
DNA polymerase iota isoform a (long)3003
DNA polymerase kappa isoform 13003
muscarinic acetylcholine receptor M11001
lethal factor (plasmid)2002
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump0606
Epidermal growth factor receptor0101
Carbonic anhydrase 10707
Carbonic anhydrase 20707
Fatty acid-binding protein, liver0101
Integrin beta-33104
Myeloperoxidase0202
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb3104
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10202
Adenosine receptor A2a0202
Substance-P receptor0101
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3003
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-14105
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Canalicular multispecific organic anion transporter 10202
Sigma non-opioid intracellular receptor 10011
Sigma non-opioid intracellular receptor 10011
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, Cruzipain2002
phosphopantetheinyl transferase3003
USP1 protein, partial4004
Microtubule-associated protein tau4004
vitamin D3 receptor isoform VDRA6006
caspase-1 isoform alpha precursor1001
lamin isoform A-delta105005
Caspase-71001
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10203
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A2002
RAR-related orphan receptor gamma9009
apical membrane antigen 1, AMA12002
nonstructural protein 10101
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
Chain A, Ferritin light chain3003
acetylcholinesterase3003
hypoxia-inducible factor 1 alpha subunit4004
SMAD family member 22002
SMAD family member 32002
TDP1 protein6006
GLI family zinc finger 35005
caspase 7, apoptosis-related cysteine protease3003
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 35005
progesterone receptor3003
retinoid X nuclear receptor alpha7007
farnesoid X nuclear receptor4004
67.9K protein1001
peroxisome proliferator activated receptor gamma7007
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-33003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
activating transcription factor 64004
thyrotropin-releasing hormone receptor1001
v-jun sarcoma virus 17 oncogene homolog (avian)3003
thyroid hormone receptor beta isoform 27007
heat shock protein beta-13003
mitogen-activated protein kinase 11001
nuclear factor erythroid 2-related factor 2 isoform 1110011
nuclear receptor ROR-gamma isoform 12002
survival motor neuron protein isoform d4004
Voltage-dependent calcium channel gamma-2 subunit3003
Cellular tumor antigen p534004
Glutamate receptor 23003
Caspase-20011
ATPase family AAA domain-containing protein 52002
Ataxin-22002
pregnane X nuclear receptor6006
G4004
aryl hydrocarbon receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
geminin6006
streptokinase A precursor0011
Dihydroxyacetone phosphate acyltransferase0001
Interferon beta4004
HLA class I histocompatibility antigen, B alpha chain 4004
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cytochrome P450 3A40101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Inositol hexakisphosphate kinase 14004
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial4004
Carbonic anhydrase 40202
Carbonic anhydrase0101
Carbonic anhydrase 150202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40505
Chain A, Beta-lactamase3003
Luciferase4004
glp-1 receptor, partial2002
15-lipoxygenase, partial1001
Estrogen receptor 10011
Smad31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
bromodomain adjacent to zinc finger domain 2B3003
TPA: protein transporter TIM100101
beta-2 adrenergic receptor2002
lysosomal alpha-glucosidase preproprotein3003
cellular tumor antigen p53 isoform a3003
polyunsaturated fatty acid lipoxygenase ALOX121001
potassium voltage-gated channel subfamily H member 2 isoform d1001
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
cytochrome P450 3A4 isoform 14004
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
Gamma-aminobutyric acid receptor subunit pi4004
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Neuronal acetylcholine receptor subunit alpha-43003
Neuronal acetylcholine receptor subunit beta-23003
Gamma-aminobutyric acid receptor subunit beta-14004
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Alpha-synuclein1001
Histamine H2 receptor2002
Spike glycoprotein4004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
Rap guanine nucleotide exchange factor 41001
GABA theta subunit4004
Gamma-aminobutyric acid receptor subunit epsilon4004
Cathepsin B0101
Furin0101
Amiloride-sensitive amine oxidase [copper-containing]0101
Diamine acetyltransferase 10101
Acid-sensing ion channel 10101
Acid-sensing ion channel 20101
histone deacetylase 9 isoform 32002
nonstructural protein 12002
Histone H2A.x2002
cytochrome P450 2C9 precursor1001
chromobox protein homolog 13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
glycogen synthase kinase-3 beta isoform 10011
Aldo-keto reductase family 1 member B100101
Transient receptor potential cation channel subfamily A member 10011
Transient receptor potential cation channel subfamily M member 20101
Dihydrofolate reductase0101
Beta-lactamase0101
Myc proto-oncogene protein0101
Cytochrome P450 2C9 0202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Malate dehydrogenase, cytoplasmic0101
Aldo-keto reductase family 1 member C30202
Cytochrome P450 2J20101
Aldo-keto reductase family 1 member C2 0202
Aldo-keto reductase family 1 member C10202
Peroxisome proliferator-activated receptor alpha1001
NACHT, LRR and PYD domains-containing protein 3 0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
WRN1001
Valosin-containing protein0101
thioredoxin glutathione reductase2002
regulator of G-protein signaling 41001
thyroid stimulating hormone receptor2002
thyroid hormone receptor beta isoform a2002
transcriptional regulator ERG isoform 31001
microphthalmia-associated transcription factor isoform 90101
DNA polymerase beta1001
flap endonuclease 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
eukaryotic translation initiation factor 4E isoform 10101
muscleblind-like protein 1 isoform 11001
histone acetyltransferase KAT2A isoform 11001
Rap guanine nucleotide exchange factor 31001
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
alpha-galactosidase1001
Polyphenol oxidase 20001
Carbonic anhydrase 120101
Endolysin0011
Carbonic anhydrase 30101
Gamma-aminobutyric acid receptor subunit alpha-10011
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit gamma-20011
Cannabinoid receptor 10101
Carbonic anhydrase 60404
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit beta-20011
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 90101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Carbonic anhydrase 30303
Carbonic anhydrase0101
Carbonic anhydrase 130101
Carbonic anhydrase 130101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
GALC protein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
peripheral myelin protein 222002
5-hydroxytryptamine receptor 2A0011
Bile salt export pump0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Fumarate hydratase1001
polyprotein1001
Cystine/glutamate transporter0101
Chain A, Methionine aminopeptidase0101
BRCA11001
pregnane X receptor1001
ATAD5 protein, partial1001
P531001
pyruvate kinase1001
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
cytochrome P450 2C19 precursor1001
ras-related protein Rab-9A1001
Cytochrome P450 1A20101
Methionine aminopeptidase0101
Endothelin receptor type B1001
Endothelin-1 receptor1001
Methionine aminopeptidase 20101
Methionine aminopeptidase 10112
Peptidyl-prolyl cis-trans isomerase FKBP1A0011
Fatty-acid amide hydrolase 10101
Reverse transcriptase/RNaseH 0101
Multidrug and toxin extrusion protein 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]