| Member | Definition | Class |
|---|
| acequinocyl | An acetate ester consisting of 1,4-naphthoquinone bearing acetoxy and dodecyl substituents at positions 2 and 3 respectively. | acequinocyl |
| ametoctradin | A member of the class of triazolopyrimidines that is [1,2,4]triazolo[1,5-a]pyrimidin-7-amine carrying additional ethyl and octyl substituents at positions 5 and 6 respectively. A fungicide for the control of late blight and downey mildew on potatoes and other crops including vines. | ametoctradin |
| azoxystrobin | An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture. | azoxystrobin |
| cyazofamid | A member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms. | cyazofamid |
| fenamidone | A member of the class of imidazolones that is 3,5-dihydroimidazol-4-one substituted at position 2 by a methylthiogroup, at position 3 by an anilino group and at position 5 by phenyl and methyl groups (the S-enantiomer). A fungicide effective against Oomycete diseases such as downy mildew and certain leaf spot diseases. | fenamidone |
| fluacrypyrim | | fluacrypyrim |
| fluoxastrobin | An oxime O-ether that is the O-methyl oxime of (2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone. A fungicide used for disease control of potatoes and a wide range of vegetables. | fluoxastrobin |
| kresoxim-methyl | A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. | kresoxim-methyl |
| picoxystrobin | An enoate ester that is the methyl ester of (2E)-3-methoxy-2-[2-({[6-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]prop-2-enoic acid. A cereal fungicide used to control a wide range of diseases including brown rust, tan spot, powdery mildew and net blotch. | picoxystrobin |
| pyrachlostrobin | A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres. | pyraclostrobin |
| strobilurin b | An enoate ester that is the methyl ester of (2E,3Z,5E)-6-(4-chloro-3-methoxyphenyl)-2-(methoxymethylene)-3-methylhexa-3,5-dienoic acid. | strobilurin B |
| trifloxystrobin | The methyl ester of (2E)-(methoxyimino)[2-({[(E)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetic acid. A foliar applied fungicide for cereals which is particularly active against Ascomycetes, Deuteromycetes and Oomycetes | trifloxystrobin |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 89.3584 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 1.0962 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 13.6017 | 10 | 61 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 28.7104 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 12.1847 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 12.1847 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 23.3598 | 3 | 17 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 1.2622 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 31.7055 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 20.0048 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 48.4256 | 1 | 7 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 17.4781 | 12 | 67 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 27.1175 | 2 | 11 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 8.0059 | 9 | 44 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 28.0689 | 3 | 14 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 1.2622 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 6.9539 | 3 | 15 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 13.7301 | 4 | 12 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 11.3854 | 1 | 6 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 23.7689 | 2 | 4 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 31.6180 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 15.9623 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 1.2622 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 43.0700 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 1.2622 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 14.1454 | 2 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 37.7446 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 10.0777 | 4 | 19 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 35.7322 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 19.2556 | 3 | 16 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 23.4255 | 5 | 23 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 26.1039 | 4 | 21 |
| polyprotein | Zika virus | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 26.4080 | 2 | 11 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 12.0914 | 1 | 5 |
| progesterone receptor | Homo sapiens (human) | Potency | 39.7170 | 2 | 8 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.2295 | 2 | 14 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 16.2986 | 3 | 16 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 25.9862 | 4 | 15 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 33.8902 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 33.8902 | 2 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 0.2302 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 3.7261 | 3 | 15 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 20.1035 | 2 | 7 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 42.9433 | 4 | 8 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 47.8358 | 2 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 31.2698 | 3 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 11.3854 | 1 | 6 |