Pericarditis, Tuberculous

INFLAMMATION of the sac surrounding the heart (PERICARDIUM) due to MYCOBACTERIUM TUBERCULOSIS infection. Pericarditis can lead to swelling (PERICARDIAL EFFUSION), compression of the heart (CARDIAC TAMPONADE), and preventing normal beating of the heart.

Synonym
Pericarditis, Tuberculous
Tuberculous Pericarditis

Excerpt	Reference
"Tuberculous pericarditis is common in Transkei (Eastern Cape)."	( Casbard, A; Gibson, DG; Girling, DJ; Johnson, DA; Nunn, AJ; Strang, JI, 2004)
"Tuberculous pericarditis is associated with high morbidity and mortality even if antituberculosis therapy is administered."	( Aje, A; Ansa, V; Awotedu, AA; Barasa, AF; Bosch, J; Brown, B; Chitsa Banda, A; Damasceno, A; Danbauchi, S; Essop, MR; Francis, V; Gumedze, F; Hakim, J; Joldersma, L; Jung, H; Kirenga, B; Magula, NP; Manga, P; Matenga, J; Mayosi, BM; Mntla, P; Mondo, C; Naidoo, DP; Ntsekhe, M; Ogah, O; Ojji, D; Olunuga, T; Pandie, S; Peters, F; Pogue, J; Russell, JB; Sani, MU; Smieja, M; Thabane, L; Thomas, B; Thomas, KM; Tsitsi, JM; Yusuf, S, 2014)
"Tuberculous pericarditis is common in immunocompromised patients or in immunocompetent patients in endemic areas."	( Chang, SA, 2017)
"Tuberculous pericarditis is a less common but more lethal form of tuberculosis and has a similar inflammatory process in the pericardium."	( Raubenheimer, P; Ross, I; Shenje, JT; Wiesner, L, 2023)

Excerpt	Reference
"Tuberculous pericarditis has been proved by the following examinations: pericardium puncture (21 cases), pericardium and pleural biopsy (respectively 11 and 13 cases), ganglionic biopsy and search of alcohol-acid-fast bacilli in sputum: 1 case."	( Auregan, G; Chanteau, S; Lesbordes, JL; Pecarrere, JL; Rakotoniaina, D; Ramanampisoa, C; Rasoamahenina, B; Razafindramboa, H, 1995)
"Tuberculous pericarditis has decreased in incidence, but early diagnosis and treatment are critical because constrictive pericarditis is a serious complication of this condition."	( Hayashi, H; Kawamata, H; Kumazaki, T; Machida, M, 1998)

Excerpt	Reference
"Here, we describe an unusual case of tuberculous pericarditis that shows marked increased FDG uptake on initial scan, with decreasing metabolic activity on follow-up scan indicating response to antituberculosis therapy."	( Gokcek, A; Koksal, D; Ozcan, A; Ozmen, O; Tatci, E, 2014)
"The diagnosis of tuberculous pericarditis usually requires a multidisciplinary approach, and presumptive treatment should be started for people with suspected infections living in endemic areas."	( Chang, SA, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	44 (41.90)	23.3326
1990's	14 (13.33)	12.5806
2000's	12 (11.43)	18.1394
2010's	31 (29.52)	28.8240
2020's	4 (3.81)	9.53

Drug	Relationship Strength	Studies	Trials
niacin	low	2	0
pyrazinamide	low	5	0
aspirin	low	2	0
fluconazole	low	1	0
isoniazid	medium	15	1
aminosalicylic acid	low	5	0
procaine	low	1	0
sulfasalazine	low	1	0
prednisolone	medium	30	6
prednisone	low	7	0
colchicine	low	2	0
methylprednisolone	low	1	0
ethambutol	low	6	0
streptomycin	low	21	0
technetium	low	2	0
trolamine salicylate	low	1	0
cephapirin	low	1	0
goralatide	low	2	0
fluorodeoxyglucose f18	low	5	0
voriconazole	low	1	0
cortisone	low	3	0
digoxin	low	1	0
technetium tc 99m pyrophosphate	low	1	0
gadolinium dtpa	low	1	0
mocetinostat	low	1	0
clove	low	2	0
sodium pertechnetate tc 99m	low	1	0
cardiovascular agents	low	2	0
muramidase	low	1	0
rifampin	low	10	0
allopurinol	low	1	0
trifazid	low	1	0

Protein Targets (399)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
interleukin 8	5	0	0	5
TDP1 protein	6	0	0	6
AR protein	13	0	0	13
thyroid stimulating hormone receptor	7	0	0	7
estrogen receptor 2 (ER beta)	5	0	0	5
progesterone receptor	7	0	0	7
glucocorticoid receptor [Homo sapiens]	12	0	0	12
estrogen-related nuclear receptor alpha	10	0	0	10
estrogen nuclear receptor alpha	15	0	0	15
IDH1	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
Bloom syndrome protein isoform 1	2	0	0	2
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	5	0	0	5
ras-related protein Rab-9A	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
geminin	8	0	0	8
survival motor neuron protein isoform d	2	0	0	2
lamin isoform A-delta10	6	0	0	6
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
Polyphenol oxidase 2	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Bile salt export pump	0	16	0	16
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	7	0	0	7
Glutamate receptor 2	4	0	0	4
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	4	0	0	4
Canalicular multispecific organic anion transporter 1	0	11	0	11
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Microtubule-associated protein tau	3	0	0	3
thioredoxin glutathione reductase	4	0	0	4
Smad3	3	0	0	3
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Carbonic anhydrase 1	0	6	0	6
Carbonic anhydrase 2	0	6	0	6
Tyrosine-protein phosphatase non-receptor type 1	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	6	0	0	6
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thioredoxin reductase	5	0	0	5
GLS protein	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
EWS/FLI fusion protein	4	0	0	4
retinoic acid nuclear receptor alpha variant 1	11	0	0	11
cytochrome P450 2D6	4	0	0	4
glucocerebrosidase	2	0	0	2
peroxisome proliferator-activated receptor delta	7	0	0	7
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	2	0	0	2
DNA polymerase kappa isoform 1	1	0	0	1
muscarinic acetylcholine receptor M1	4	0	0	4
lethal factor (plasmid)	3	0	0	3
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	1	1	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	1	1	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	4	1	1	6
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	4	1	0	5
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Chain A, Beta-lactamase	3	0	0	3
Chain A, Ferritin light chain	1	0	0	1
Luciferase	3	0	0	3
endonuclease IV	2	0	0	2
PAX8	0	0	0	2
pregnane X receptor	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
RAR-related orphan receptor gamma	9	0	0	9
ATAD5 protein, partial	5	0	0	5
Fumarate hydratase	1	0	0	1
USP1 protein, partial	3	0	0	3
PPM1D protein	4	0	0	4
GLI family zinc finger 3	10	0	0	10
Thrombopoietin	1	0	0	1
nuclear receptor subfamily 1, group I, member 3	5	0	0	5
retinoid X nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	9	0	0	9
polyprotein	1	0	0	1
67.9K protein	3	0	0	3
peroxisome proliferator activated receptor gamma	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
aryl hydrocarbon receptor	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
activating transcription factor 6	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
cytochrome P450 2D6 isoform 1	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	2	0	0	2
chromobox protein homolog 1	5	0	0	5
thyroid hormone receptor beta isoform a	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
flap endonuclease 1	2	0	0	2
steroidogenic factor 1	0	1	0	1
peripheral myelin protein 22	1	0	0	1
cytochrome P450 3A4 isoform 1	4	0	0	4
muscleblind-like protein 1 isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Solute carrier family 22 member 3	0	1	0	1
Interferon beta	8	0	0	8
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	1	6
Cytochrome P450 3A4	0	6	0	6
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
ATP-dependent translocase ABCB1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Histamine H2 receptor	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
GABA theta subunit	4	0	0	4
CREB-binding protein	1	0	0	1
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
Tubulin beta-1 chain	0	2	2	5
ATP-dependent phosphofructokinase	3	0	0	3
dopamine D1 receptor	2	0	0	2
regulator of G-protein signaling 4	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
peripheral myelin protein 22 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
heat shock protein beta-1	2	0	0	2
M-phase phosphoprotein 8	1	0	0	1
Glucocorticoid receptor	0	10	2	17
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	10	0	10
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Cruzipain	2	0	0	2
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
STAT3, partial	0	1	0	1
alpha-galactosidase	1	0	0	1
thyroid stimulating hormone receptor	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Solute carrier organic anion transporter family member 1B1	0	5	0	6
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
acetylcholinesterase	3	0	0	3
apical membrane antigen 1, AMA1	1	0	0	1
G	5	0	0	5
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	3	0	3
Rap guanine nucleotide exchange factor 3	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	2	3
Aromatase	0	1	0	1
Cytochrome P450 2C9	0	5	1	6
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	2	0	2
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	3	0	3
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	2	0	2
Inositol hexakisphosphate kinase 1	5	0	0	5
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
14-alpha sterol demethylase	0	0	2	2
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
cytochrome P450 2C9, partial	5	0	0	5
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
phosphopantetheinyl transferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
N-glycosylase/DNA lyase	0	1	0	1
Bile salt export pump	0	4	0	4
Cytochrome P450 1A2	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Cytochrome P450 2C19	0	3	0	3
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
nonstructural protein 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Androgen receptor	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Integrin alpha-4	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Nuclear receptor corepressor 2	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
glp-1 receptor, partial	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	2	0	2
Estrogen receptor beta	0	2	0	2
vitamin D3 receptor isoform VDRA	2	0	0	2
arylsulfatase A	1	0	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
15-lipoxygenase, partial	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Albumin	0	0	1	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	2	0	2
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Protein-arginine deiminase type-4	0	2	0	2
Chain A, Glutathione S-transferase	0	1	0	1
Histone H2A.x	1	0	0	1
Replicase polyprotein 1ab	0	0	1	1
histone deacetylase 9 isoform 3	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Thromboxane-A synthase	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Sodium/bile acid cotransporter	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
mitogen-activated protein kinase 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (105)

Protein Targets (399)

Pericarditis, Tuberculous

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (105)

Drugs Studied (38)

Protein Targets (399)