Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group.
ChEBI ID: 35496
Member | Definition | Role |
---|---|---|
hexafluorobenzene | A member of the class of fluorobenzenes that is benzene in which all six hydrogen atom have been replaced by fluorine. | hexafluorobenzene |
pentafluorobenzyl bromide | A member of the class benzyl bromides that is benzyl bromide in which the hydrogens at positions 2, 3, 4, 5 and 6 of the phenyl ring are replaced by fluoro groups. It is a versatile derivatization agent in chromatography and mass spectrometry. | pentafluorobenzyl bromide |
ravuconazole | A member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14alpha demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4) | ravuconazole |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 16 (6.35) | 18.7374 |
1990's | 49 (19.44) | 18.2507 |
2000's | 100 (39.68) | 29.6817 |
2010's | 63 (25.00) | 24.3611 |
2020's | 24 (9.52) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 7 (2.68%) | 5.53% |
Reviews | 18 (6.90%) | 6.00% |
Case Studies | 5 (1.92%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 231 (88.51%) | 84.16% |