Hyperkyphosis

Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.

Synonym
Hyperkyphosis
Kyphosis

Excerpt	Reference
"Kyphosis is commonly associated with ageing and osteoporosis of the spine."	( Chow, RK; Harrison, JE, 1987)
"Severe kyphosis is a frequent complication of multiple laminectomies for the treatment of intraspinal tumors in growing children."	( Dormans, JP; Drummond, DS; Torpey, BM, 1995)
"Kyphosis is not only associated with relatively altered vertebral body shape (anterior wedging), but also with reduced bone density and fitness, as well as decreased muscle strength, and is associated with reduced survival."	( Cutler, WB; Friedmann, E; Genovese-Stone, E, 1993)
"Thoracic kyphosis is a risk factor for vertebral fractures over three years and influences physical capacity changes in postmenopausal women with osteoporosis."	( Benhamou, CL; Briot, K; Fechtenbaum, J; Kolta, S; Roux, C; Said-Nahal, R, 2010)
"Congenital cervical kyphosis is a rare clinical condition."	( Dricot, F; Hachimi-Idrissi, S; van Berlaer, G; Van Gorp, V; Van Rompaey, K, 2009)
"Such kyphosis is severely disabling with significant risk of neurological deficit and respiratory compromise."	( Rajasekaran, S; Rishi Mugesh Kanna, P; Shetty, AP, 2011)
"Kyphosis is an idiopathic disease characterized by abnormal, outward spinal curvature."	( Crenshaw, TD; Rortvedt, LA, 2012)
"lordosis or kyphosis) are of importance in the development of spinal disorders."	( Brismée, JM; Coomans, Y; Dugailly, PM; Klein, P; Salem, W; Sobczak, S, 2015)
"Non-syndromic kyphosis is a common disorder that is associated with significant morbidity and has a strong genetic involvement; however, the causative genes remain to be identified, as such studies are hampered by genetic heterogeneity, small families and various modes of inheritance."	( Brown, MA; Brown, SD; Cox, RD; Croucher, PI; Esapa, CT; Loh, NY; Nesbit, MA; Piret, SE; Thakker, RV; Thomas, G, 2016)

Excerpt	Reference
"The kyphosis has been observed to be influenced by weight and spinal length."	( Sidhu, LS; Singal, P, 1983)

Excerpt	Reference
"The role of kyphosis in the development of lung function during therapy is being discussed."	( Kummer, F; Meznik, F; Pflüger, G, 1975)
"Severe kyphosis is a frequent complication of multiple laminectomies for the treatment of intraspinal tumors in growing children."	( Dormans, JP; Drummond, DS; Torpey, BM, 1995)
"If predictive, the impact of kyphosis on physical function should be considered in osteoporosis prevention and treatment counseling."	( Fried, LP; Ryan, SD, 1997)
"A 32-year-old man with congenital kyphosis treated with prednisolone daily for 5 months for interstitial lung disease developed compressive myelopathy."	( Gupta, R; Gupta, V; Kumar, AN; Madhavan, SM; Sharma, SK, 2007)
"Degrees of kyphosis and scoliosis before, during, and after treatment were measured, and levels of instrumentation, thoracic dimensions, and complications were recorded."	( Patil, V; Reinker, K; Simmons, JW; Stinson, Z, 2011)
"Progression of kyphosis can be minimized during VEPTR(®) treatment by early extension of the construct to the second ribs bilaterally, distal extension of hybrid constructs to the pelvis, use of bilateral hybrid VEPTR(®) implants, and use of redesigned VEPTR(®) constructs that enhance fixation at the upper end."	( Patil, V; Reinker, K; Simmons, JW; Stinson, Z, 2011)
"The value of the kyphosis index in AB-treated mice reached 94% of the value in C57BL/10 mice."	( Benoit, E; Boerio, D; Bouyon, S; de la Porte, S; Fromes, Y; Herbin, M; Roulot, M; Sebrié, C; Vianello, S, 2014)
"A 66-year-old man with kyphosis who had been treated with nocturnal noninvasive positive-pressure ventilation developed PH with a mean pulmonary arterial pressure (PAP) of 32 mmHg and a pulmonary vascular resistance (PVR) of 5."	( Okada, S; Sugawara, A; Takeuchi, S; Watanuki, Z; Yamagata, S, 2018)
"Pain scores, kyphosis angle of fractured vertebra (VKA), and spinopelvic alignment, including pelvic incidence minus lumbar lordosis (PI-LL), were assessed periodically during treatment."	( Hashimoto, T; Iwasaki, N; Iwata, A; Kanayama, M; Oha, F; Shimamura, Y; Takahata, M, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	150 (34.64)	23.3326
1990's	32 (7.39)	12.5806
2000's	93 (21.48)	18.1394
2010's	97 (22.40)	28.8240
2020's	61 (14.09)	9.53

Drug	Relationship Strength	Studies	Trials
methane	low	2	0
creatine	low	1	0
lactic acid	low	1	0
glycerol	low	1	0
hydrogen carbonate	low	1	0
homogentisic acid	low	1	0
dihydroxyphenylalanine	low	2	0
kynurenine	low	1	0
melatonin	low	1	0
nickel	low	1	0
nitrous oxide	low	4	0
parathion	low	1	0
pyrazinamide	low	5	0
pyridoxine	low	1	0
uric acid	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
aminopropionitrile	low	6	0
phenytoin	low	1	0
acetaminophen	low	1	0
alendronate	low	1	0
amantadine	low	1	0
diatrizoic acid	low	1	0
theophylline	low	2	0
amlodipine	low	1	0
baclofen	low	1	0
benzo(a)pyrene	low	1	0
bupivacaine	low	6	0
buspirone	low	1	0
caffeine	low	1	0
celecoxib	low	1	0
cetylpyridinium	low	1	0
ciprofloxacin	low	1	0
clonidine	low	1	0
diazepam	low	1	0
dimefline	low	1	0
erythrosine	low	1	0
etidronate	medium	2	1
fentanyl	low	3	0
fluoxetine	low	1	0
furosemide	low	1	0
gabapentin	medium	1	1
gentamicin	low	1	0
glyphosate	low	1	0
guaifenesin	low	1	0
haloperidol	low	2	0
halothane	low	2	0
lidocaine	low	1	0
isoflurane	low	1	0
isoniazid	medium	18	4
2-propanol	low	1	0
ketamine	low	3	0
khellin	low	1	0
kynurenic acid	low	1	0
losartan	low	1	0
mepivacaine	low	1	0
metoclopramide	low	1	0
midazolam	low	1	0
apnea	low	2	0
nifedipine	low	1	0
aminosalicylic acid	medium	5	1
pamidronate	low	2	0
pentoxifylline	low	1	0
phenobarbital	low	1	0
phenolphthalein	low	2	0
phenoxybenzamine	low	1	0
pindolol	low	1	0
propofol	medium	3	1
riluzole	low	1	0
sevoflurane	low	4	0
risedronic acid	medium	1	1
succinylcholine	low	1	0
sulfasalazine	medium	1	1
tetracaine	low	1	0
thalidomide	low	3	0
theobromine	low	1	0
tranexamic acid	low	3	0
zolpidem	low	1	0
prednisolone	low	2	0
hydroxyproline	low	2	0
prednisone	low	2	0
carbon tetrachloride	low	1	0
lysine	low	3	0
cyanides	low	3	0
tubocurarine	low	1	0
galactose	low	1	0
levodopa	low	1	0
methionine	low	1	0
tryptophan	low	1	0
arginine	low	4	0
methylmethacrylate	low	2	0
methylprednisolone	low	5	0
4-phenylenediamine	low	1	0
pyrroles	low	1	0
thiophenes	low	1	0
betamethasone	low	1	0
homocystine	low	1	0
reticulin	low	1	0
medroxyprogesterone	low	1	0
lithium carbonate	low	1	0
docusate	low	3	0
clopamide	low	1	0
ethylnitrosourea	low	2	0
ethambutol	low	4	0
3,3',4',5-tetrachlorosalicylanilide	low	1	0
durapatite	medium	5	1
vancomycin	low	1	0
d-alpha tocopherol	low	1	0
streptomycin	medium	11	3
carbenicillin	low	1	0
manganese	low	1	0
niobium	medium	1	1
osmium	low	1	0
protactinium	low	1	0
technetium	low	2	0
thorium	low	1	0
titanium	medium	47	5
chromium	low	2	0
xenon	low	4	0
barium sulfate	low	2	0
calcium phosphate, dibasic, anhydrous	low	2	0
calcium phosphate, monobasic, anhydrous	low	2	0
tricalcium phosphate	medium	14	3
calcium sulfate	low	6	0
fluorine	low	2	0
chlorine	low	1	0
trolamine salicylate	low	11	0
fluorides	low	3	0
1-deoxynojirimycin	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
4-methoxyamphetamine	low	2	0
etoposide	low	1	0
methyldopa	low	1	0
desflurane	low	1	0
propiconazole	low	1	0
fomesafen	low	5	0
miglustat	low	1	0
itraconazole	low	1	0
remifentanil	medium	2	1
ibandronic acid	low	1	0
fluorexon	low	1	0
cephalosporin c	low	1	0
clarithromycin	low	1	0
fibrinogen	low	1	0
homocysteine	low	2	0
foxes	low	1	0
cobalt	medium	4	1
pyridinoline	low	2	0
tadalafil	low	1	0
pentosidine	low	2	0
mk 0663	low	1	0
methotrexate	low	1	0
1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane	medium	1	1
calcium pyrophosphate	low	2	0
technetium tc 99m pentetate	medium	1	1
aminopterin	low	1	0
esketamine	low	1	0
cortisone	low	2	0
povidone-iodine	low	1	0
glycogen	low	2	0
elastin	low	1	0
inositol 3-phosphate	low	1	0
rocuronium	low	1	0
metrizamide	low	1	0
tretinoin	low	1	0
retinol	low	1	0
cocaine	low	1	0
keratan sulfate	low	1	0
dactinomycin	low	1	0
melphalan	low	1	0
bromochloroacetic acid	low	1	0
mercaptopurine	low	1	0
tamoxifen	low	2	0
thiopental	low	2	0
ranitidine	low	1	0
lithium	low	1	0
dermatan sulfate	low	1	0
citramalate	low	1	0
osteoprotegerin	low	1	0
calcitriol	low	1	0
cholecalciferol	low	2	0
phenylephrine hydrochloride	low	2	0
oxycodone	medium	2	1
sirolimus	low	1	0
morphine	medium	5	2
iloprost	low	1	0
aluminum	medium	1	1
enalapril	low	1	0
silicon	low	1	0
phosphorus	low	6	0
selenium	low	1	0
everolimus	low	1	0
leucyl-leucine-methyl ester	low	1	0
losartan potassium	low	1	0
dihydrotachysterol	low	2	0
acid phosphatase	low	2	0
jaw	medium	2	1
vonoprazan	low	1	0
natriuretic peptide, c-type	low	1	0
vendex	low	7	0
arginine butyrate	low	1	0
ro13-9904	low	1	0
sodium ethylxanthate	low	1	0
piperidines	medium	3	1
chondroitin	low	1	0
ascorbic acid	low	1	0
acenocoumarol	low	1	0
epidermal growth factor	low	1	0
kaolinite	low	1	0
transforming growth factor beta	low	4	0
bgp 15	low	1	0
epoetin alfa	low	1	0
technetium tc 99m medronate	low	1	0
acyclovir	low	1	0
cyclic gmp	low	1	0
folic acid	low	4	0
rifampin	medium	8	1
olanzapine	low	1	0
alcian blue	low	1	0

Protein Targets (1,623)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	6	0	0	6
thioredoxin reductase	28	0	0	28
USP1 protein, partial	31	0	0	31
TDP1 protein	46	0	0	46
vitamin D3 receptor isoform VDRA	19	0	0	19
importin subunit beta-1 isoform 1	12	0	0	12
flap endonuclease 1	13	0	0	13
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	7	0	0	7
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	15	0	0	15
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
geminin	45	0	0	45
DNA polymerase kappa isoform 1	13	0	0	13
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	2	0	2
Beta-lactamase	0	1	0	1
Transthyretin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	1	4	5
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	2	0	2
Guanine nucleotide-binding protein G	4	0	0	4
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	2	2	4
Mitogen-activated protein kinase 14	0	5	2	7
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	25	0	0	25
glucocerebrosidase	5	0	0	5
Alpha-mannosidase	0	1	0	1
alpha-galactosidase	6	0	0	6
Trehalase	0	2	0	2
lysosomal alpha-glucosidase preproprotein	7	0	0	7
Trehalase	0	1	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Trehalase	0	2	0	2
Lysosomal acid glucosylceramidase	0	4	1	5
Alpha-galactosidase A	0	1	0	1
Alpha-glucosidase MAL62	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Lysosomal alpha-glucosidase	0	4	0	4
Beta-glucosidase A	0	1	0	1
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1B adrenergic receptor	0	20	1	21
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1D adrenergic receptor	0	13	1	14
Beta-glucosidase	0	1	0	1
Protein-lysine 6-oxidase	0	5	0	5
Alpha-mannosidase 2	0	2	0	2
Glycogen debranching enzyme	0	2	0	2
Glycogen debranching enzyme	0	1	0	1
Alpha-glucosidase MAL32	0	1	0	1
Alpha-1A adrenergic receptor	0	21	2	23
Oligo-1,6-glucosidase IMA1	0	1	0	1
Alpha-glucosidase MAL12	0	2	0	2
Oxysterols receptor LXR-beta	0	1	0	1
Spike glycoprotein	26	0	1	27
Alpha-amylase	0	1	0	1
Trehalose synthase/amylase TreS	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Oxysterols receptor LXR-alpha	0	1	0	1
Neutral alpha-glucosidase AB	0	2	0	2
Ceramide glucosyltransferase	0	2	0	2
Lysosomal acid glucosylceramidase	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Beta-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Cytosolic beta-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	2	0	2
Putative alpha-glucosidase	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	19	0	0	19
RAR-related orphan receptor gamma	51	0	0	51
GLI family zinc finger 3	55	0	0	55
AR protein	64	0	0	64
aldehyde dehydrogenase 1 family, member A1	38	0	0	38
retinoic acid nuclear receptor alpha variant 1	50	0	0	50
retinoid X nuclear receptor alpha	40	0	0	40
estrogen nuclear receptor alpha	68	0	0	68
peroxisome proliferator-activated receptor delta	28	0	0	28
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	32	0	0	32
activating transcription factor 6	21	0	0	21
v-jun sarcoma virus 17 oncogene homolog (avian)	24	0	0	24
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform a	15	0	0	15
heat shock protein beta-1	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 1	46	0	0	46
lamin isoform A-delta10	41	0	0	41
Voltage-dependent calcium channel gamma-2 subunit	30	0	0	30
Glutamate receptor 2	31	1	0	33
Luciferase	19	0	0	19
acetylcholinesterase	24	0	0	24
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
estrogen receptor 2 (ER beta)	22	0	0	22
nuclear receptor subfamily 1, group I, member 3	43	0	0	43
progesterone receptor	33	0	0	33
glucocorticoid receptor [Homo sapiens]	44	0	0	44
estrogen-related nuclear receptor alpha	49	0	0	49
farnesoid X nuclear receptor	30	0	0	30
pregnane X nuclear receptor	43	0	0	43
peroxisome proliferator activated receptor gamma	33	0	0	33
vitamin D (1,25- dihydroxyvitamin D3) receptor	40	0	0	40
aryl hydrocarbon receptor	28	0	0	28
thyrotropin-releasing hormone receptor	7	0	0	7
thyroid hormone receptor beta isoform 2	39	0	0	39
histone deacetylase 9 isoform 3	5	0	0	5
Cellular tumor antigen p53	38	0	0	38
Sporulation initiation phosphotransferase F	0	1	0	1
Sporulation kinase A	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	9
Thromboxane-A synthase	0	4	0	4
Mitogen-activated protein kinase 1	0	3	2	5
Prostaglandin G/H synthase 2	0	6	1	9
5-hydroxytryptamine receptor 2C	0	15	1	18
5-hydroxytryptamine receptor 2A	0	17	1	18
5-hydroxytryptamine receptor 1A	0	20	2	22
5-hydroxytryptamine receptor 1B	0	12	1	13
5-hydroxytryptamine receptor 1D	0	6	1	7
5-hydroxytryptamine receptor 1F	0	6	1	7
5-hydroxytryptamine receptor 2B	0	14	1	15
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	12	3	15
Sodium-dependent serotonin transporter	0	10	1	12
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 4	0	2	1	4
5-hydroxytryptamine receptor 3B	0	3	1	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
Microtubule-associated protein tau	23	0	0	23
cytochrome P450 family 3 subfamily A polypeptide 4	39	0	0	39
G	23	0	0	23
cytochrome P450 2D6	24	0	0	24
euchromatic histone-lysine N-methyltransferase 2	55	0	0	55
thyroid stimulating hormone receptor	19	0	0	19
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
peripheral myelin protein 22	29	0	0	29
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	23	0	0	23
Inositol hexakisphosphate kinase 1	23	0	0	23
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	21	0	0	21
cytochrome P450 2C9, partial	23	0	0	23
chromobox protein homolog 1	34	0	0	34
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
muscleblind-like protein 1 isoform 1	7	0	0	7
ATAD5 protein, partial	14	0	0	14
GLS protein	22	0	0	22
Smad3	12	0	0	12
thyroid stimulating hormone receptor	20	0	0	20
EWS/FLI fusion protein	21	0	0	21
cytochrome P450 3A4 isoform 1	26	0	0	26
Gamma-aminobutyric acid receptor subunit pi	26	10	2	38
ATP-binding cassette sub-family C member 3	0	44	0	44
Multidrug resistance-associated protein 4	0	44	0	47
Solute carrier family 22 member 6	0	4	0	5
Carbonic anhydrase 12	0	5	1	11
UDP-glucuronosyltransferase 1A9	0	1	0	4
Bile salt export pump	0	12	0	12
Bile salt export pump	0	64	0	64
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	16	1	24
Carbonic anhydrase 2	0	16	2	24
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	3	1	5
Cytochrome P450 1A2	0	9	1	12
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 3	0	5	1	10
Cytochrome P450 3A4	0	20	2	25
Cytochrome P450 2D6	0	11	1	12
Cytochrome P450 2C9	0	18	1	20
Polyunsaturated fatty acid lipoxygenase ALOX15	0	8	0	8
Gamma-aminobutyric acid receptor subunit beta-1	26	10	2	38
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	26	10	2	38
Gamma-aminobutyric acid receptor subunit gamma-2	26	10	3	39
UDP-glucuronosyltransferase 1-6	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	26	10	2	38
Gamma-aminobutyric acid receptor subunit alpha-3	26	10	2	38
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	4
Carbonic anhydrase 4	0	8	1	13
Carbonic anhydrase 6	0	5	1	10
Gamma-aminobutyric acid receptor subunit gamma-1	26	10	2	38
Gamma-aminobutyric acid receptor subunit alpha-2	26	10	2	38
Gamma-aminobutyric acid receptor subunit alpha-4	26	10	2	38
Gamma-aminobutyric acid receptor subunit gamma-3	26	10	2	38
Gamma-aminobutyric acid receptor subunit alpha-6	26	10	2	38
Carbonic anhydrase 5A, mitochondrial	0	5	1	11
Carbonic anhydrase 7	0	5	1	10
Nuclear receptor ROR-gamma	12	1	1	14
Cytochrome P450 2J2	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	26	11	3	40
Gamma-aminobutyric acid receptor subunit beta-3	26	10	2	38
Gamma-aminobutyric acid receptor subunit beta-2	26	10	3	39
Carbonic anhydrase 9	0	6	1	12
GABA theta subunit	26	10	2	38
Canalicular multispecific organic anion transporter 1	0	42	0	43
Carbonic anhydrase 15	0	6	0	9
Carbonic anhydrase 13	0	4	0	8
Gamma-aminobutyric acid receptor subunit epsilon	26	10	2	38
Carbonic anhydrase 14	0	5	1	11
Carbonic anhydrase 5B, mitochondrial	0	5	1	11
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	14	0	0	14
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
GALC protein	5	0	0	5
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	20	0	0	20
Carbonic anhydrase	0	2	0	2
Bloom syndrome protein isoform 1	20	0	0	20
survival motor neuron protein isoform d	16	0	0	16
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	4	0	4
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2A6	0	2	0	2
Androgen receptor	0	10	0	10
Translocator protein	0	4	2	7
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	9	0	12
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	7	1	13
Delta-type opioid receptor	0	6	0	7
Cytochrome P450 2C19	0	9	1	10
Delta-type opioid receptor	0	9	1	11
Mu-type opioid receptor	0	11	2	16
Carbonic anhydrase	0	5	0	7
Kappa-type opioid receptor	0	7	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	4	2	0	6
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	2	0	4
D(2) dopamine receptor	0	14	0	14
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	8	0	8
Fatty-acid amide hydrolase 1	0	3	0	3
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	8	0	12
Squalene synthase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	3	0	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	4	0	4
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	8	0	8
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	5
Carbonic anhydrase 4	0	4	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	22	0	0	22
Chain B, HADH2 protein	22	0	0	22
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Chain A, Ferritin light chain	14	0	0	14
Thymidine kinase	0	1	0	1
phosphopantetheinyl transferase	22	0	0	22
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	10	0	0	10
Solute carrier family 22 member 1	0	9	0	13
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	0	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
Thymidine kinase	0	1	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	5	0	5
Farnesyl pyrophosphate synthase	0	8	0	8
Acetylcholinesterase	0	7	0	7
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	2	0	2
NFKB1 protein, partial	9	0	0	9
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	19	0	0	19
putative alpha-glucosidase	1	0	0	1
histone acetyltransferase KAT2A isoform 1	19	0	0	19
Solute carrier family 22 member 2	0	4	0	5
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 1	0	8	0	12
Glutamate receptor ionotropic, NMDA 2A	0	7	0	11
Glutamate receptor ionotropic, NMDA 2C	0	7	0	11
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	7	0	11
Solute carrier family 22 member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	7	0	11
Multidrug and toxin extrusion protein 1	0	9	0	9
Solute carrier family 22 member 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	7	0	11
ATP-dependent phosphofructokinase	23	0	0	23
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	13	0	0	13
Dihydrofolate reductase	0	7	0	8
Dihydrofolate reductase	0	4	0	6
Dihydrofolate reductase	0	3	0	5
Dihydrofolate reductase	0	3	3	6
Folylpolyglutamate synthase, mitochondrial	0	2	0	6
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	6
Chain A, 2-oxoglutarate Oxygenase	18	0	0	18
thioredoxin glutathione reductase	12	0	0	12
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	0	1	1
IDH1	17	0	0	17
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	20	0	0	20
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Potassium channel subfamily K member 2	0	4	6	10
ATP-dependent translocase ABCB1	0	14	2	22
Alpha-2A adrenergic receptor	0	14	2	17
Alpha-2C adrenergic receptor	0	8	1	10
Alpha-2B adrenergic receptor	0	10	1	11
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Alpha-2C adrenergic receptor	0	10	1	11
Alpha-2A adrenergic receptor	0	10	1	11
Alpha-1D adrenergic receptor	0	11	1	13
Alpha-1A adrenergic receptor	0	4	1	6
Alpha-1B adrenergic receptor	0	4	1	6
5-hydroxytryptamine receptor 6	0	10	0	10
Sodium-dependent dopamine transporter	0	10	1	11
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	9
Potassium channel subfamily K member 2	0	2	0	2
D(1A) dopamine receptor	10	0	0	10
neuropeptide S receptor isoform A	1	0	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
cytochrome P450 2C19 precursor	6	0	0	6
muscarinic acetylcholine receptor M1	20	0	0	20
lethal factor (plasmid)	11	0	0	11
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	2	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	12	2	15
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
67.9K protein	11	0	0	11
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
glp-1 receptor, partial	10	0	0	10
apical membrane antigen 1, AMA1	6	0	0	6
caspase 7, apoptosis-related cysteine protease	11	0	0	11
caspase-3	11	0	0	11
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Tyrosine-protein kinase Fyn	0	4	2	6
Amine oxidase [flavin-containing] A	0	5	0	5
Aryl hydrocarbon receptor	0	0	2	2
pregnane X receptor	11	0	0	11
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	12	2	19
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	4	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
cytochrome P450 2D6 isoform 1	9	0	0	9
cytochrome P450 2C9 precursor	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
5-hydroxytryptamine receptor 1A	0	8	5	13
Beta-2 adrenergic receptor	0	3	0	4
Angiotensin-converting enzyme	0	3	0	3
D(2) dopamine receptor	0	11	1	14
Beta-1 adrenergic receptor	0	2	0	3
D	0	8	0	8
D(3) dopamine receptor	0	8	0	8
D(2) dopamine receptor	0	4	0	4
D(1B) dopamine receptor	0	6	0	6
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	14	0	14
5-hydroxytryptamine receptor 2C	0	18	0	18
D(4) dopamine receptor	0	7	0	7
5-hydroxytryptamine receptor 7	0	3	0	3
D(3) dopamine receptor	0	11	1	14
5-hydroxytryptamine receptor 2B	0	14	0	14
5-hydroxytryptamine receptor 3A	0	2	1	3
Histamine H2 receptor	11	0	0	12
Potassium voltage-gated channel subfamily H member 2	0	24	0	25
Alpha-2A adrenergic receptor	0	2	0	2
D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
D	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	16	0	16
Lysosomal alpha-glucosidase	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
DNA polymerase beta	4	0	0	4
Cholinesterase	0	3	0	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Adenosine receptor A3	0	10	0	10
Replicase polyprotein 1ab	0	2	1	3
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	9	0	9
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	7	3	12
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A2b	0	4	1	7
Adenosine receptor A1	0	7	2	13
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	3	2	5
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	3	5
Endochitinase B1	0	4	1	5
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	8
Guanine deaminase	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
PPM1D protein	4	0	0	4
mitogen-activated protein kinase 1	15	0	0	15
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	3	0	3
Vitamin D3 receptor	0	2	3	8
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	3	5
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	4	0	4
Vitamin D3 receptor A	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Cytochrome P450 2E1	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	10	0	0	10
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Caspase-7	7	0	0	7
interferon gamma precursor	0	0	0	3
prostaglandin E2 receptor EP2 subtype	0	0	0	1
caspase-3	7	0	0	7
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	4	1	5
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Procathepsin L	0	1	1	2
Aldo-keto reductase family 1 member B1	0	12	0	12
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	2	0	4
Quinolone resistance protein NorA	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	2	0	4
Beta-3 adrenergic receptor	0	6	1	7
Calpain-2 catalytic subunit	0	1	0	1
D(1A) dopamine receptor	0	8	0	9
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	15	1	16
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Urotensin-2 receptor	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Histone deacetylase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Alpha-synuclein	5	3	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
Caspase-2	0	0	1	1
Inositol monophosphatase 1	7	0	0	7
interleukin 8	6	0	0	6
15-lipoxygenase, partial	13	0	0	13
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	15	0	0	15
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	4	0	4
Glycine receptor subunit alpha-1	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	4	0	4
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	2	3	13
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
streptokinase A precursor	0	0	2	2
Solute carrier organic anion transporter family member 1B3	0	9	0	11
Solute carrier organic anion transporter family member 1B1	0	8	0	9
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	3	0	3
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	0	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Nischarin	0	2	0	2
Nischarin	0	1	0	1
TAR DNA-binding protein 43	8	0	0	8
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Amyloid-beta precursor protein	0	3	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	8	4	12
Gamma-aminobutyric acid receptor subunit beta-1	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	3	10
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	5	1	6
Gamma-aminobutyric acid receptor subunit beta-3	0	8	2	10
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	3	10
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit beta-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	1	8
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	8	0	8
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	1	8
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Leukotriene B4 receptor 2	0	1	0	2
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
Transporter	0	5	0	5
endonuclease IV	7	0	0	7
dopamine D1 receptor	5	0	0	5
peripheral myelin protein 22 isoform 1	10	0	0	10
M-phase phosphoprotein 8	10	0	0	10
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Phosphodiesterase	0	4	0	4
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	5	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	6	0	6
Deoxycytidine kinase	0	0	0	1
Rap guanine nucleotide exchange factor 3	4	0	0	4
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
huntingtin isoform 2	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
caspase-1 isoform alpha precursor	2	0	0	2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	3	0	0	3
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	3	0	3
Discoidin domain-containing receptor 2	0	1	2	3
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Gamma-aminobutyric acid	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	4	7
Albumin	0	0	4	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Epidermal growth factor receptor	0	4	2	6
Glutamate receptor 1	1	1	0	3
Glutamate receptor 3	1	1	0	3
Glutamate receptor 4	1	1	0	3
Angiotensin-converting enzyme	0	7	0	7
Type-2 angiotensin II receptor	0	4	0	4
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Angiotensin-converting enzyme 2	0	1	1	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Fumarate hydratase	8	0	0	8
hypothetical protein, conserved	3	0	0	3
polyprotein	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
eyes absent homolog 2 isoform a	2	0	0	2
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	3	0	3
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	3	10
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	3
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	1	2	3
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	0	3	3
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	0	2	2
Tyrosine-protein kinase Lck	0	2	2	4
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	2	4
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	1	2	3
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
Protein kinase C theta type	0	1	2	3
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	7	0	7
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(4) dopamine receptor	0	7	1	10
Kappa-type opioid receptor	0	6	1	8
Histamine H1 receptor	0	5	1	6
Mu-type opioid receptor	0	9	4	14
Delta-type opioid receptor	0	6	2	9
Kappa-type opioid receptor	0	6	2	9
Mu-type opioid receptor	0	3	2	7
Sigma non-opioid intracellular receptor 1	0	4	0	4
Multidrug resistance-associated protein 1	0	0	0	2
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	16	0	16
Sodium channel protein type 1 subunit alpha	0	2	0	2
Muscarinic acetylcholine receptor M5	0	8	0	9
Muscarinic acetylcholine receptor M1	0	7	1	9
Dipeptidyl peptidase 4	0	1	0	1
Muscarinic acetylcholine receptor M3	0	7	0	8
Acetylcholinesterase	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	5	0	5
Beta-2 adrenergic receptor	0	2	0	3
Histamine H3 receptor	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	5	0	5
Thymidylate synthase	0	3	0	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Multidrug resistance associated protein	0	1	0	3
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	3	0	3
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Sodium/bile acid cotransporter	0	2	0	2
G-protein coupled receptor 35	0	3	2	5
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Thrombopoietin	2	0	0	2
nonstructural protein 1	7	0	0	7
Adenylate cyclase type 1	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Major prion protein	0	0	1	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Muscarinic acetylcholine receptor M2	0	4	0	5
Muscarinic acetylcholine receptor M4	0	5	0	6
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Muscarinic acetylcholine receptor M2	0	3	0	3
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	3
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	4
5-hydroxytryptamine receptor 3A	0	2	0	2
Histamine H2 receptor	0	4	0	4
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	5	0	6
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	1	4
Sodium channel protein type 9 subunit alpha	0	6	0	6
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Adenylyl cyclase 7	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	5	0	5
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	3	0	3
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	0	1	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	0	1	1
Prostacyclin receptor	0	2	1	3
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	1	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	4	0	4
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Chymotrypsinogen A	0	1	0	1
Acetylcholinesterase	0	3	0	3
Parkin	6	0	0	6
Glutamate receptor ionotropic, kainate 1	0	1	0	2
Glutamate receptor ionotropic, kainate 2	0	1	0	2
Glutamate receptor ionotropic, kainate 3	0	1	0	2
Glutamate receptor ionotropic, kainate 4	0	1	0	2
G protein-coupled receptor GPR35	0	0	1	1
Glutamate receptor ionotropic, kainate 5	0	1	0	2
Vesicular glutamate transporter 3	0	1	0	1
Histamine H3 receptor	0	0	1	1
cellular tumor antigen p53 isoform a	8	0	0	8
Integrin beta-3	7	0	0	7
Integrin alpha-IIb	7	0	0	7
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	3	0	0	3
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Plasma kallikrein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	3	0	3
SLC16A10 protein	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
phosphoglycerate kinase	2	0	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Neprilysin	0	1	0	1
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Type-1A angiotensin II receptor	0	3	1	4
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	2	1	5
Type-1 angiotensin II receptor	0	1	1	2
Type-2 angiotensin II receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	5	0	5
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	4
PINK1	1	0	0	1
ClpP	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Aromatase	0	1	0	1
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Carboxylic ester hydrolase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Reduced folate transporter	0	2	0	2
Pteridine reductase 1	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	3	0	3
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
5-hydroxytryptamine receptor 3E	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	1	2
5-hydroxytryptamine receptor 3C	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sucrase-isomaltase	0	1	0	1
Ceramide glucosyltransferase	0	1	0	1
Beta-galactosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	2	5
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
tumor necrosis factor	1	0	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Histamine H1 receptor	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
Tumor necrosis factor	0	1	1	2
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
G-protein coupled receptor 55	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Thymidylate synthase	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	2	2
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	2	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	4	1	5
5-hydroxytryptamine receptor 1B	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	4	1	6
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Histamine H4 receptor	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	2	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	2
Butyrophilin subfamily 3 member A1	0	0	1	1
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	1	0	1
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	1	1	2
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
Replicase polyprotein 1ab	0	0	2	2
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	1	2
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Synaptic vesicular amine transporter	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	1	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
Spike glycoprotein	0	0	1	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Substance-K receptor	0	2	0	2
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
cGMP-gated cation channel alpha-1	0	0	1	1
Cereblon isoform 4	0	2	0	2
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Phospholipase A-2-activating protein	0	2	0	2
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Stromelysin-1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (433)

Protein Targets (1,623)

Hyperkyphosis

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (433)

Drugs Studied (253)

Protein Targets (1,623)