Page last updated: 2024-09-27

Atrophic Muscular Disorders

Disorders characterized by an abnormal reduction in muscle volume due to a decrease in the size or number of muscle fibers. Atrophy may result from diseases intrinsic to muscle tissue (e.g., MUSCULAR DYSTROPHY) or secondary to PERIPHERAL NERVOUS SYSTEM DISEASES that impair innervation to muscle tissue (e.g., MUSCULAR ATROPHY, SPINAL).

Synonyms(5)

Synonym
Atrophy, Spinopontine
Atrophic Muscular Disorders
Atrophy, Disuse
Spinopontine Atrophy
Muscular Disorders, Atrophic

Research Excerpts

Overview

ExcerptReference
"Muscle disuse atrophy is observed in patients recovering from trauma and there is an increased risk and severity of injury in patients abusing alcohol (EtOH)."( Lang, CH; Vargas, R, 2008)

Research

Studies (114)

TimeframeStudies, This Condition (%)All Conditions %
pre-19903 (2.63)23.3326
1990's0 (0.00)12.5806
2000's43 (37.72)18.1394
2010's62 (54.39)28.8240
2020's6 (5.26)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetylcarnitine0low10
carnitine0low30
chlorine0low10
creatine0low10
dimethyl sulfoxide0low10
hydrogen0low10
thioctic acid0low10
trimethyloxamine0low10
alendronate0low10
caffeine0low10
clenbuterol0low10
diclofenac0low10
carbonyl cyanide p-trifluoromethoxyphenylhydrazone0low10
flutamide0low10
losartan0low10
naratriptan0low20
patulin0low10
pentobarbital0low10
pioglitazone0low10
glutamine0low20
lysine0low10
phenylethyl alcohol0low10
leucine0low10
valine0low10
tryptophan0low10
isoleucine0low10
isosorbide dinitrate0low10
thiazoles0low10
pyrazines0low20
chlormadinone acetate0medium11
monocrotaline0low10
dihydrotestosterone0low40
malondialdehyde0low10
tetramethylpyrazine0low20
streptomycin0low10
gadolinium0low10
glutamic acid0low10
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid0low10
lovastatin0low10
simvastatin0low10
duloxetine hydrochloride0low10
glucose, (beta-d)-isomer0low10
zoledronic acid0low10
beta-hydroxyisovaleric acid0low20
3,4-dihydroxyphenylethanol0low10
nicotine0low10
indo-10low10
valerates0low20
glucitollysine0low10
angiotensin ii, des-phe(8)-0low30
angiotensin ii0low10
n-(3-pyridylmethyl)adriamycin0low10
arimoclomol0low10
leupeptins0low10
glycogen0low10
ouabain0low10
digitoxin0low10
rocuronium0low10
neriifolin0low10
lignans0low10
resveratrol0low10
eicosapentaenoic acid0low10
thapsigargin0low10
benzyloxycarbonylleucyl-leucyl-leucine aldehyde0low10
8-prenylnaringenin0low10
leuprolide0medium111
curcumin0low10
thiourea0low10
osteoprotegerin0low10
furylfuramide0low10
genistein0low10
coenzyme q100low10
pregabalin0low10
salubrinal0low10
tetrodotoxin0low20
mkt 0770low10
tanespimycin0low30
beta-escin0low10
suloctidil0low10
staurosporine0low10
phosphocreatine0low10
pd 1506060low10
mocetinostat0low10
cannogenin thevetoside0low10
acid phosphatase0low10
nad0low10
sauvagine0low20
oligonucleotides0low10
vendex0medium41
ubiquinone0low10
calpain0medium21
ro13-99040low10
piperidines0low20
heme0low10
transforming growth factor beta0medium52
calpastatin0low10
angiotensin i0low30
peoniflorin0low10
deoxyguanosine0low20
allopurinol0low20
8-hydroxy-2'-deoxyguanosine0low20
eye0low20

Protein Targets (948)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Polyunsaturated fatty acid 5-lipoxygenase0404
Chain A, Beta-lactamase100010
GLS protein110011
euchromatic histone-lysine N-methyltransferase 2220022
geminin190019
Polyphenol oxidase 20303
Acetylcholinesterase0606
Prostaglandin G/H synthase 10404
Sodium-dependent dopamine transporter0101
Prostaglandin G/H synthase 20606
Xanthine dehydrogenase/oxidase0404
Dehydrogenase/reductase SDR family member 90101
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Voltage-dependent T-type calcium channel subunit alpha-1G0101
Voltage-dependent T-type calcium channel subunit alpha-1H0101
Estrogen receptor0426
Amine oxidase [flavin-containing] A0707
Amine oxidase [flavin-containing] B0909
NAD(P)H dehydrogenase [quinone] 10003
Estrogen receptor beta0325
Broad substrate specificity ATP-binding cassette transporter ABCG20505
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0304
Farnesyl pyrophosphate synthase0404
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0303
Farnesyl pyrophosphate synthase 0202
interleukin 85005
TDP1 protein210021
AR protein210021
thyroid stimulating hormone receptor100010
estrogen receptor 2 (ER beta)110011
progesterone receptor130013
glucocorticoid receptor [Homo sapiens]170017
estrogen-related nuclear receptor alpha190019
estrogen nuclear receptor alpha240024
IDH17007
Bloom syndrome protein isoform 17007
transcriptional regulator ERG isoform 34004
thyroid hormone receptor beta isoform 2150015
ras-related protein Rab-9A6006
nuclear factor erythroid 2-related factor 2 isoform 1170017
survival motor neuron protein isoform d110011
lamin isoform A-delta10140014
ATP-binding cassette sub-family C member 3011011
Multidrug resistance-associated protein 4011011
Voltage-dependent calcium channel gamma-2 subunit110011
Bile salt export pump017017
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p53150015
Glutamate receptor 2122115
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0427
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0315
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 435005
Canalicular multispecific organic anion transporter 1010010
Shiga toxin subunit A0101
Histamine H3 receptor0101
glucocerebrosidase3003
DNA polymerase kappa isoform 1120012
histone acetyltransferase KAT2A isoform 15005
Atrial natriuretic peptide receptor 30202
Type-1A angiotensin II receptor 0426
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0404
Type-1 angiotensin II receptor0439
Type-2 angiotensin II receptor0404
Type-2 angiotensin II receptor0303
Proteasome subunit beta type-110101
Fumarate hydratase4004
PPM1D protein6006
aldehyde dehydrogenase 1 family, member A1140014
EWS/FLI fusion protein100011
polyprotein4004
vitamin D3 receptor isoform VDRA120012
Calpain-90101
Proteasome subunit alpha type-70101
Interferon beta130013
Cathepsin B0101
Replicase polyprotein 1ab0314
Replicase polyprotein 1ab0516
Aromatase0607
Indoleamine 2,3-dioxygenase 10203
Calpain-2 catalytic subunit0101
Proteasome subunit beta type-10202
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
NF-kappa-B inhibitor alpha0011
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50404
Proteasome subunit beta type-100101
Cathepsin K0101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20202
Proteasome subunit alpha type-60101
Proteasome subunit alpha-type 80101
Proteasome subunit beta type-70101
Gamma-secretase subunit PEN-20101
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase9009
RAR-related orphan receptor gamma160016
GLI family zinc finger 3180018
nuclear receptor subfamily 1, group I, member 3110011
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha160016
farnesoid X nuclear receptor120012
pregnane X nuclear receptor140014
thyroid stimulating hormone receptor9009
v-jun sarcoma virus 17 oncogene homolog (avian)100010
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 16006
thyroid hormone receptor beta isoform a9009
DNA polymerase beta5005
nuclear receptor ROR-gamma isoform 1110011
muscarinic acetylcholine receptor M12002
lethal factor (plasmid)4004
Potassium channel subfamily K member 20011
Glycogen phosphorylase, muscle form0202
Renin0101
Carbonic anhydrase 10508
Carbonic anhydrase 20609
Cholinesterase0404
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Adenosine receptor A30101
Adenosine receptor A10203
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10518
Adenosine receptor A2a0406
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0202
Serine/threonine-protein kinase ATR0202
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0102
Phosphodiesterase 0101
Guanine deaminase0101
ATP-dependent phosphofructokinase6006
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, Ferritin light chain7007
Chain A, Cruzipain7007
15-lipoxygenase, partial6006
Microtubule-associated protein tau110011
cellular tumor antigen p53 isoform a6006
cytochrome P450 3A4 isoform 1100010
Gamma-aminobutyric acid receptor subunit pi100111
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Integrin beta-36017
Integrin alpha-IIb6017
Gamma-aminobutyric acid receptor subunit beta-1100111
Gamma-aminobutyric acid receptor subunit delta100111
Gamma-aminobutyric acid receptor subunit gamma-2100111
Gamma-aminobutyric acid receptor subunit alpha-5100111
Gamma-aminobutyric acid receptor subunit alpha-3100111
Gamma-aminobutyric acid receptor subunit gamma-1100111
Gamma-aminobutyric acid receptor subunit alpha-2100111
Gamma-aminobutyric acid receptor subunit alpha-4100111
Gamma-aminobutyric acid receptor subunit gamma-3100111
Gamma-aminobutyric acid receptor subunit alpha-6100111
Histamine H2 receptor6006
Gamma-aminobutyric acid receptor subunit alpha-1100111
Gamma-aminobutyric acid receptor subunit beta-3100111
Gamma-aminobutyric acid receptor subunit beta-2100111
Inositol monophosphatase 13003
Hypoxia-inducible factor 1-alpha0101
GABA theta subunit100111
Endothelial PAS domain-containing protein 10101
Gamma-aminobutyric acid receptor subunit epsilon100111
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Carbonic anhydrase 40203
Carbonic anhydrase0102
Carbonic anhydrase 150203
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
acetylcholinesterase5005
SMAD family member 29009
ATAD5 protein, partial8008
SMAD family member 39009
thioredoxin glutathione reductase4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
cytochrome P450 family 3 subfamily A polypeptide 4100010
G7007
bromodomain adjacent to zinc finger domain 2B5005
peroxisome proliferator-activated receptor delta130013
peroxisome proliferator activated receptor gamma140014
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
activating transcription factor 66006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
nuclear receptor subfamily 1, group I, member 24004
nuclear factor erythroid 2-related factor 2 isoform 26006
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
importin subunit beta-1 isoform 13003
mitogen-activated protein kinase 15005
snurportin-13003
peripheral myelin protein 229009
neuropeptide S receptor isoform A2002
HLA class I histocompatibility antigen, B alpha chain 7007
Glucocorticoid receptor0305
Glycine receptor subunit alpha-10202
Androgen receptor09110
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Cytochrome P450 2C190303
Spike glycoprotein7007
Inositol hexakisphosphate kinase 17007
cytochrome P450 2C9, partial7007
regulator of G-protein signaling 47007
cytochrome P450 2D69009
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0202
5-hydroxytryptamine receptor 1A0405
5-hydroxytryptamine receptor 1B0202
Delta-type opioid receptor0112
Beta-2 adrenergic receptor 0013
Beta-2 adrenergic receptor0011
ATPase family AAA domain-containing protein 59009
Ataxin-2100010
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10304
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, 2-oxoglutarate Oxygenase5005
Luciferase3003
Nrf21001
thioredoxin reductase9009
pregnane X receptor3003
hypoxia-inducible factor 1 alpha subunit4004
USP1 protein, partial7007
alkaline phosphatase, intestinal0101
Smad36006
apical membrane antigen 1, AMA11001
caspase 7, apoptosis-related cysteine protease4004
PINK13003
Parkin6006
toll-like receptor 90101
caspase-34004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)6006
TPA: protein transporter TIM100101
aryl hydrocarbon receptor110011
thyrotropin-releasing hormone receptor3003
Histone H2A.x6006
lysosomal alpha-glucosidase preproprotein2002
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0101
hemoglobin subunit beta1001
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
perilipin-50101
intestinal alkaline phosphatase precursor0101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d7007
heat shock protein beta-15005
huntingtin isoform 23003
pyruvate kinase PKM isoform a1001
nuclear factor NF-kappa-B p105 subunit isoform 11012
flap endonuclease 14004
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase iota isoform a (long)4004
urokinase-type plasminogen activator precursor6006
plasminogen precursor6006
urokinase plasminogen activator surface receptor precursor6006
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
muscleblind-like protein 1 isoform 13003
DNA dC->dU-editing enzyme APOBEC-3G isoform 12204
alkaline phosphatase, germ cell type preproprotein0101
caspase-1 isoform alpha precursor1001
hypothetical protein SA14220101
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Prostaglandin E synthase0101
Histone deacetylase 30404
Acetylcholinesterase0202
Lysine-specific histone demethylase 1A0202
D-amino-acid oxidase0101
Phospholipase A20101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10314
Amyloid-beta precursor protein0214
Neuronal proto-oncogene tyrosine-protein kinase Src 0101
Prostaglandin G/H synthase 10314
Heme oxygenase 1 0101
Glutathione S-transferase P0101
60 kDa chaperonin0101
Microtubule-associated protein tau0102
60 kDa heat shock protein, mitochondrial0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Tissue factor0202
Tyrosinase0202
Aminopeptidase N0101
Aminopeptidase N0101
Alpha-1B adrenergic receptor0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20202
Glycogen synthase kinase-3 beta0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Heme oxygenase 20101
Alpha-1D adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
17-beta-hydroxysteroid dehydrogenase type 20202
Alpha-synuclein3115
Alpha-1A adrenergic receptor0101
Glycogen synthase kinase-3 beta0101
Nuclear receptor ROR-gamma8008
Caspase-71001
Histone deacetylase 40303
Beta-secretase 10101
10 kDa heat shock protein, mitochondrial0101
Guanine nucleotide-binding protein G1001
Cholinesterase0202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
Serine/threonine-protein kinase PAK 10202
Histone deacetylase 10606
5-hydroxytryptamine receptor 40011
Sodium/bile acid cotransporter0011
Nuclear factor erythroid 2-related factor 20023
Thiosulfate sulfurtransferase0101
Thioredoxin reductase 1, cytoplasmic0202
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Thioredoxin reductase 30202
Sortase A0101
Histone deacetylase 70303
Histone deacetylase 20606
CREB-binding protein0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30202
Cysteine protease 0101
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0303
NACHT, LRR and PYD domains-containing protein 3 0101
Histone deacetylase 80404
Thioredoxin reductase 2, mitochondrial0202
CDGSH iron-sulfur domain-containing protein 10404
Histone deacetylase 60404
Histone deacetylase 90202
Histone deacetylase 50303
Lymphocyte antigen 960011
Beta lactamase (plasmid)0101
67.9K protein6006
Thymidine kinase, cytosolic0102
Deoxycytidine kinase0001
AAA family ATPase 0001
Sterol O-acyltransferase 10101
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90102
Prostaglandin G/H synthase 1 0202
Transient receptor potential cation channel subfamily A member 10134
Dihydrofolate reductase0303
Cytochrome c oxidase subunit 20101
Fatty acid-binding protein, liver0101
Transthyretin0125
Albumin0112
Cytochrome P450 3A40505
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Cytochrome P450 2C9 0304
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10303
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 1A40101
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 2 0101
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0101
Cytochrome P450 2J20101
Prostaglandin G/H synthase 20303
Prostaglandin G/H synthase 20101
Carbonic anhydrase 90304
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Carbonic anhydrase 40101
Multidrug and toxin extrusion protein 10202
P2Y purinoceptor 120101
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
STAT3, partial0202
NPC intracellular cholesterol transporter 1 precursor5005
signal transducer and activator of transcription 1-alpha/beta isoform alpha0202
Sodium/potassium-transporting ATPase subunit alpha-1 0304
Sodium/potassium-transporting ATPase subunit beta-10304
Sodium/potassium-transporting ATPase subunit alpha-30203
Sodium/potassium-transporting ATPase subunit beta-20203
Sodium/potassium-transporting ATPase subunit alpha-20304
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30203
Sodium/potassium-transporting ATPase subunit gamma0203
Sodium/potassium-transporting ATPase subunit alpha-40203
Solute carrier organic anion transporter family member 4C10102
Chain A, Sex Hormone-Binding Globulin0011
glp-1 receptor, partial5005
Plasma kallikrein0102
Sex hormone-binding globulin0123
Progesterone receptor0101
Progesterone receptor0112
Glucocorticoid receptor0101
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0101
Sex hormone-binding globulin0101
Androgen receptor05210
Androgen receptor0112
Mineralocorticoid receptor0101
Testosterone 17-beta-dehydrogenase 30202
Angiotensin-converting enzyme0011
Cannabinoid receptor 20101
G-protein coupled bile acid receptor 10011
Neuropeptide FF receptor 20001
ALK tyrosine kinase receptor0101
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
Trypsin0101
Cytochrome P450 1A20303
Coagulation factor VII0101
Retinoic acid receptor RXR-alpha0101
Peroxisome proliferator-activated receptor gamma0236
Oxoeicosanoid receptor 10101
endonuclease IV1001
nonstructural protein 11001
alpha-galactosidase1001
peripheral myelin protein 22 isoform 16006
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor3003
D(1A) dopamine receptor3003
M-phase phosphoprotein 84004
Cocaine esterase0102
Bile salt export pump0303
Arylacetamide deacetylase0001
5-hydroxytryptamine receptor 60202
Arylacetamide deacetylase0001
Arylacetamide deacetylase0001
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
acid sphingomyelinase1001
BRCA12002
Thrombopoietin1001
Neuraminidase 0101
P532002
Alpha-mannosidase0101
pyruvate kinase2002
hexokinase-4 isoform 12002
histone deacetylase 9 isoform 32002
glucokinase regulatory protein2002
glycogen synthase kinase-3 beta isoform 10011
tyrosine-protein kinase Yes2002
pyruvate kinase PKM isoform b1001
Maltase-glucoamylase, intestinal0202
5-hydroxytryptamine receptor 40202
Steroid hormone receptor ERR20101
Tyrosine-protein kinase ABL10304
Epidermal growth factor receptor0101
Pancreatic triacylglycerol lipase0101
Triosephosphate isomerase0101
Tyrosine-protein kinase Fyn0101
Cyclin-dependent kinase 10101
ATP-dependent translocase ABCB10316
Ornithine decarboxylase1001
Sialidase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Tyrosinase0303
Steroid hormone receptor ERR10101
Cyclin-dependent kinase 40101
Ornithine decarboxylase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Proto-oncogene tyrosine-protein kinase Src0101
Cystic fibrosis transmembrane conductance regulator0011
17-beta-hydroxysteroid dehydrogenase type 10101
Solute carrier family 2, facilitated glucose transporter member 40101
G2/mitotic-specific cyclin-B10101
Dipeptidyl peptidase 40101
Protein kinase C alpha type0112
cAMP-dependent protein kinase catalytic subunit alpha0101
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0101
G1/S-specific cyclin-D10101
Thromboxane-A synthase 0101
Cruzipain0101
DNA (cytosine-5)-methyltransferase 10101
Dipeptidyl peptidase 40202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Substance-P receptor0202
Sodium-dependent serotonin transporter0101
RAC-alpha serine/threonine-protein kinase0101
Cystic fibrosis transmembrane conductance regulator0011
Acetylcholinesterase0101
Alpha-glucosidase MAL320101
Signal transducer and activator of transcription 30101
Tyrosine-protein kinase CSK0101
Tyrosine-protein kinase ABL20101
Tyrosine-protein kinase SYK0101
Dual specificity mitogen-activated protein kinase kinase 40101
Quinone oxidoreductase0001
Cytoplasmic tyrosine-protein kinase BMX0101
Death-associated protein kinase 10101
Mitogen-activated protein kinase 100101
Oxysterols receptor LXR-beta0101
Amine oxidase [flavin-containing] B0101
MO15-related protein kinase Pfmrk 0101
Sodium-dependent dopamine transporter 0404
Aldehyde oxidase0101
Oxysterols receptor LXR-alpha0101
Mitogen-activated protein kinase 140101
Tissue alpha-L-fucosidase0101
Substance-K receptor0101
Integrase 0101
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0101
Prenyltransferase homolog0002
Carboxylic ester hydrolase 0101
Solute carrier organic anion transporter family member 1B30404
Dipeptidyl peptidase 30101
DNA (cytosine-5)-methyltransferase 3-like0101
Sialidase-20101
DNA (cytosine-5)-methyltransferase 3A0101
Solute carrier organic anion transporter family member 1B10606
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0214
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, NMDA 2A 0214
Glutamate receptor ionotropic, NMDA 2B0214
Glutamate receptor ionotropic, NMDA 2C0214
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0214
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0214
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0214
Chain A, Glutamine Binding Protein0011
arylsulfatase A5005
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Large neutral amino acids transporter small subunit 10404
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
Neprilysin0101
Angiotensin-converting enzyme 0101
Thromboxane A2 receptor 0102
Type-1 angiotensin II receptor0112
Squalene synthase0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0102
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Platelet glycoprotein VI0113
Type-1 angiotensin II receptor0112
Chain A, Antigen Cd11a (p180)0101
isocitrate dehydrogenase 1, partial2002
bcl-2-related protein A10101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0303
Integrin beta-20101
Intercellular adhesion molecule 10101
Aldo-keto reductase family 1 member B10404
Neutrophil elastase0101
Insulin receptor 0202
Integrin alpha-L0112
Substance-K receptor0202
Sodium-dependent noradrenaline transporter 0617
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
Lanosterol 14-alpha demethylase0101
Rap guanine nucleotide exchange factor 42002
Acyl-CoA:cholesterol acyltransferase 0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Cationic amino acid transporter 30101
Telomerase reverse transcriptase0101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0202
Cytochrome P450 2D60101
Integrin alpha-40101
Potassium voltage-gated channel subfamily H member 20404
Nuclear receptor corepressor 20101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 3E0101
Solute carrier family 22 member 1 0001
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Muscarinic acetylcholine receptor M10213
Muscarinic acetylcholine receptor M30112
Muscarinic acetylcholine receptor M40213
Muscarinic acetylcholine receptor M50112
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-40326
Muscarinic acetylcholine receptor M20112
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60213
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-20326
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Translocator protein0101
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-50225
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Mu-type opioid receptor0101
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-70225
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Solute carrier family 22 member 10101
5-hydroxytryptamine receptor 3D0101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Transporter0113
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)0101
Chain L, Igg2b-kappa 40-50 Fab (light Chain)0101
Chain A, Na, K-ATPase alpha subunit0011
Kruppel-like factor 50101
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1A20001
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit alpha-40101
Genome polyprotein 0101
Calpain-1 catalytic subunit0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
CDGSH iron-sulfur domain-containing protein 10101
Free fatty acid receptor 10011
Peroxisome proliferator-activated receptor gamma0101
Steryl-sulfatase0101
Tyrosine-protein phosphatase non-receptor type 10202
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Amine oxidase [flavin-containing] B0101
Peroxisome proliferator-activated receptor alpha0101
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Peroxisome proliferator-activated receptor gamma0112
Carnitine O-palmitoyltransferase 1, liver isoform0101
Peroxisome proliferator-activated receptor alpha0112
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
CDGSH iron-sulfur domain-containing protein 20101
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
ClpP1001
M18 aspartyl aminopeptidase0101
cathepsin L10101
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 13003
FAD-linked sulfhydryl oxidase ALR0001
Vif0202
transcription factor p65 isoform 10011
serine/threonine-protein kinase 33 isoform a0011
POsterior Segregation0011
Aryl hydrocarbon receptor0101
Estrogen receptor beta0011
Carbonic anhydrase 120203
Myc proto-oncogene protein0102
Cytochrome P450 1A10101
Tyrosine-protein kinase Lck0101
Cathepsin D0101
Carbonic anhydrase 30102
Luciferin 4-monooxygenase0101
DNA polymerase alpha catalytic subunit0101
Breakpoint cluster region protein0203
Ribosyldihydronicotinamide dehydrogenase [quinone]0213
Estrogen receptor0011
Nuclear factor NF-kappa-B p105 subunit0101
Endothelin receptor type B1001
Carbonic anhydrase 60102
Sucrase-isomaltase, intestinal0101
Endothelin-1 receptor1001
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Nitric oxide synthase, inducible0101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
Cannabinoid receptor 10101
D(1A) dopamine receptor2002
Alpha-glucosidase MAL120101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
Bcl-2-like protein 10101
Cytochrome P450 1B10202
N1L 0101
Tubulin beta-2B chain0101
Lysosomal alpha-glucosidase0101
Transient receptor potential cation channel subfamily A member 10101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
NAD-dependent protein deacetylase sirtuin-20011
Carbonic anhydrase 130101
NAD-dependent protein deacetylase sirtuin-10013
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Carbonic anhydrase 140203
Zinc finger protein mex-50011
Carbonic anhydrase 5B, mitochondrial0102
large T antigen0101
photoreceptor-specific nuclear receptor0101
serine/threonine-protein kinase PLK11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
Nuclear receptor subfamily 4 group A member 20011
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Sigma non-opioid intracellular receptor 10101
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Protein-arginine deiminase type-40202
cytochrome P450 2D6 isoform 11001
Corticotropin releasing hormone receptor 20101
Lysine-specific demethylase 6B0101
Lysine-specific demethylase 4B0101
ATP-dependent molecular chaperone HSP820101
Receptor tyrosine-protein kinase erbB-20101
Heat shock protein HSP 90-alpha0325
Heat shock protein HSP 90-beta0226
Cholesteryl ester transfer protein0011
ATP-dependent molecular chaperone HSC820101
Lysine-specific demethylase 5A0101
Endoplasmin0112
Heat shock protein 75 kDa, mitochondrial0101
Heat-shock protein0101
Putative heat shock protein HSP 90-alpha A40101
Lysine-specific demethylase 4C0101
Sodium channel protein type 9 subunit alpha0101
DNA polymerase III, partial1001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Ubiquitin-like modifier activating enzyme 20101
SUMO1 activating enzyme subunit 10101
hexokinase0101
SUMO-conjugating enzyme UBC90101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Tat0101
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0101
serine-protein kinase ATM isoform a1001
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Urease0203
5-hydroxytryptamine receptor 2A0101
Urease subunit alpha0101
D(3) dopamine receptor0101
Urease subunit alpha0101
Urease subunit beta0101
Urease subunit beta 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Myeloperoxidase0101
Stromelysin-10101
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 130001
Carbonic anhydrase0101
Chain A, Arginase 10101
Butyrophilin subfamily 3 member A10012
72 kDa type IV collagenase0101
Matrix metalloproteinase-90101
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]