Page last updated: 2024-09-27

Hypertrophic Pyloric Stenosis

Narrowing of the pyloric canal due to HYPERTROPHY of the surrounding circular muscle. It is usually seen in infants or young children.

Synonyms(6)

Synonym
Hypertrophic Pyloric Stenosis
Infantile Hypertrophic Pyloric Stenosis
Pyloric Stenosis, Hypertrophic
Idiopathic Hypertrophic Pyloric Stenosis
Stenosis, Hypertrophic Pyloric
Primary Hypertrophic Pyloric Stenosis

Research Excerpts

Overview

ExcerptReference
"Hypertrophic pyloric stenosis is a common surgical cause of vomiting in infants."( Hall, NJ; Jobson, M, 2016)

Context

ExcerptReference
" Infants with hypertrophic pyloric stenosis have gastric outlet obstruction, indicating a pyloromyotomy."( Gonzalez Candel, A; Keyzer-Dekker, C; Staals, L; Swenker, D; van der Knijff-van Dortmont, A, 2020)

Treatment

ExcerptReference
"Infants with hypertrophic pyloric stenosis treated by UMBP in 2008-2009 were matched with LAP-treated infants."( Aspirot, A; Beaunoyer, M; Lemoine, C; Morris, M; Paris, C; Vali, K, 2011)
"atropine has a potential role in treating infantile hypertrophic pyloric stenosis (IHPS)."( Hashimoto, H; Horiguchi, H; Matsuda, S; Takeuchi, M; Yasunaga, H, 2013)
"atropine (IA) therapy of infantile hypertrophic pyloric stenosis (IHPS) are unknown."( Inoue, M; Koike, Y; Kusunoki, M; Nakazawa, M; Tsukamoto, Y; Uchida, K, 2013)
"Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood."( Abdelhafeez, A; El-Gohary, Y; Gosain, A; Murphy, AJ; Paton, E, 2018)
"The most appropriate treatment for the infantile Hypertrophic Pyloric Stenosis (HPS) is still debated."( Beretta, F; Bleve, C; Caione, P; Casadio, G; Cheli, M; Chiarenza, SF; Conforti, A; Di Benedetto, V; Escolino, M; Esposito, C; Gambino, M; Gerocarni Nappo, S; Marzaro, M; Mendoza-Sagaon, M; Molinaro, F; Pini Prato, A; Scuderi, MG, 2020)

Research

Studies (87)

TimeframeStudies, This Condition (%)All Conditions %
pre-199017 (19.54)23.3326
1990's0 (0.00)12.5806
2000's21 (24.14)18.1394
2010's39 (44.83)28.8240
2020's10 (11.49)9.53
DrugIndicatedRelationship StrengthStudiesTrials
chlorine0low50
hydrochloric acid0low10
hydrogen carbonate0low40
nitrates0low10
nitrites0low10
acetaminophen0medium21
bupivacaine0low10
chlorpromazine0low10
cimetidine0low20
fentanyl0low10
fluoxetine0low20
ibuprofen0low10
isoflurane0medium11
metoclopramide0low10
apnea0low20
nitroglycerin0low10
promazine0low10
pilocarpine0low10
methylene blue0low10
desoxycorticosterone0low10
arginine0low20
phenothiazine0low20
erythromycin0low50
streptomycin0low10
barium sulfate0low20
ammonium chloride0low20
carbimazole0low10
tramadol0low10
ng-nitroarginine methyl ester0low20
atracurium0low10
technetium tc 99m mertiatide0low10
remifentanil0medium11
cisatracurium0low10
arginine methyl ester0low10
bosentan anhydrous0low10
atropine0medium171
zithromax0medium41
ranitidine0low10
bilirubin0low10
alprostadil0medium51
morphine0low10
barium0low10
motilin0low10
sodium ethylxanthate0low10
cardiovascular agents0low10
piperidines0medium11
folic acid0low20
sildenafil citrate0low10

Protein Targets (684)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma110011
ATAD5 protein, partial5005
GLS protein7007
Microtubule-associated protein tau8008
Smad33003
aldehyde dehydrogenase 1 family, member A18008
thyroid stimulating hormone receptor7007
nuclear receptor subfamily 1, group I, member 3100010
progesterone receptor100010
EWS/FLI fusion protein3003
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha110011
estrogen-related nuclear receptor alpha160016
estrogen nuclear receptor alpha170017
peroxisome proliferator activated receptor gamma110011
aryl hydrocarbon receptor5005
chromobox protein homolog 1100010
thyroid hormone receptor beta isoform 2120012
peripheral myelin protein 226006
cytochrome P450 3A4 isoform 17007
Gamma-aminobutyric acid receptor subunit pi7007
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012014
Solute carrier family 22 member 60404
Carbonic anhydrase 120102
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0606
Voltage-dependent calcium channel gamma-2 subunit4004
Bile salt export pump019019
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10708
Carbonic anhydrase 20708
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20113
Prostaglandin G/H synthase 10303
Carbonic anhydrase 30102
Cytochrome P450 3A40618
Cytochrome P450 2D60718
Cytochrome P450 2C9 0707
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-17007
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta7007
Gamma-aminobutyric acid receptor subunit gamma-27007
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 24004
Gamma-aminobutyric acid receptor subunit alpha-57007
Gamma-aminobutyric acid receptor subunit alpha-37007
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0001
Carbonic anhydrase 40607
Prostaglandin G/H synthase 10404
Carbonic anhydrase 60203
Gamma-aminobutyric acid receptor subunit gamma-17007
Gamma-aminobutyric acid receptor subunit alpha-27007
Gamma-aminobutyric acid receptor subunit alpha-47007
Gamma-aminobutyric acid receptor subunit gamma-37007
Gamma-aminobutyric acid receptor subunit alpha-67007
Carbonic anhydrase 5A, mitochondrial0203
Prostaglandin G/H synthase 20203
Carbonic anhydrase 70203
Nuclear receptor ROR-gamma2002
Cytochrome P450 2J20606
Gamma-aminobutyric acid receptor subunit alpha-17007
Gamma-aminobutyric acid receptor subunit beta-37007
Gamma-aminobutyric acid receptor subunit beta-27007
Carbonic anhydrase 90203
GABA theta subunit7007
Canalicular multispecific organic anion transporter 1011011
Carbonic anhydrase 150505
Carbonic anhydrase 130203
Gamma-aminobutyric acid receptor subunit epsilon7007
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0203
toxin B0001
TDP1 protein130013
AR protein160016
glucocorticoid receptor [Homo sapiens]9009
Cellular tumor antigen p539009
Thromboxane-A synthase 0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10001
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
thioredoxin reductase7007
arylsulfatase A7007
euchromatic histone-lysine N-methyltransferase 2170017
Bloom syndrome protein isoform 12002
D(1A) dopamine receptor5005
lamin isoform A-delta10140014
neuropeptide S receptor isoform A2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase7007
NFKB1 protein, partial4004
alpha-galactosidase3003
cytochrome P450 2C19 precursor5005
flap endonuclease 13003
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)5005
Nitric oxide synthase, endothelial0103
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0114
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase7007
NPYLR7B0011
Amine oxidase [flavin-containing] A 0011
Small conductance calcium-activated potassium channel protein 30112
Chain A, 2-oxoglutarate Oxygenase5005
GLI family zinc finger 3120012
pregnane X nuclear receptor110011
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta4004
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 010010
5-hydroxytryptamine receptor 4012012
Muscarinic acetylcholine receptor M207212
Muscarinic acetylcholine receptor M40619
Muscarinic acetylcholine receptor M106110
Muscarinic acetylcholine receptor M306110
Muscarinic acetylcholine receptor M406110
Muscarinic acetylcholine receptor M506110
Muscarinic acetylcholine receptor M509112
Muscarinic acetylcholine receptor M206111
Muscarinic acetylcholine receptor M109315
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M308111
Alpha-1D adrenergic receptor0606
5-hydroxytryptamine receptor 2C012012
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor3217
5-hydroxytryptamine receptor 70505
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, Cruzipain2002
USP1 protein, partial9009
vitamin D3 receptor isoform VDRA5005
DNA polymerase kappa isoform 14004
caspase-1 isoform alpha precursor1001
Caspase-71001
Inositol monophosphatase 13003
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10203
estrogen receptor 2 (ER beta)6006
cytochrome P450 family 3 subfamily A polypeptide 4120012
G7007
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)7007
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 1100010
nuclear receptor ROR-gamma isoform 13003
Nuclear receptor subfamily 1 group I member 20022
Interferon beta9009
HLA class I histocompatibility antigen, B alpha chain 7007
Endothelin receptor type B0101
Endothelin receptor type B0213
Endothelin-1 receptor0202
Endothelin-1 receptor0213
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0101
Endothelin-1 receptor0101
Inositol hexakisphosphate kinase 17007
cytochrome P450 2C9, partial7007
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20213
Potassium channel subfamily K member 90101
geminin9009
Lactoperoxidase0101
Carbonic anhydrase0505
Proteasome subunit beta type-110001
acetylcholinesterase5005
Fumarate hydratase3003
Thrombopoietin2002
caspase 7, apoptosis-related cysteine protease3003
NADPH oxidase 10202
farnesoid X nuclear receptor4004
cytochrome P450 2D67007
polyprotein3003
67.9K protein3003
peroxisome proliferator-activated receptor delta7007
Snq2p0003
caspase-33003
IDH16006
Adenylate cyclase type 1 0202
thyroid stimulating hormone receptor4004
Histone H2A.x5005
Caspase-73003
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a2002
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-33003
histone deacetylase 9 isoform 32002
mitogen-activated protein kinase 13003
atrial natriuretic peptide receptor 2 precursor3003
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 13003
survival motor neuron protein isoform d4004
M-phase phosphoprotein 82002
histone acetyltransferase KAT2A isoform 14004
Proteasome subunit alpha type-70001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Epidermal growth factor receptor0202
Albumin0134
Albumin0044
Major prion protein0022
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Integrin beta-31001
Tyrosine-protein kinase Fyn0101
Procathepsin L0112
Aldo-keto reductase family 1 member B10808
ATP-dependent translocase ABCB10809
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0404
Alpha-2A adrenergic receptor0718
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0112
Angiotensin-converting enzyme0404
D(2) dopamine receptor0708
5-hydroxytryptamine receptor 2A0404
Alpha-1B adrenergic receptor0808
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0404
D0404
D(3) dopamine receptor0404
5-hydroxytryptamine receptor 1A0505
Alpha-2B adrenergic receptor0404
D(2) dopamine receptor0303
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor0405
D(4) dopamine receptor0304
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0404
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0404
Alpha-1D adrenergic receptor0606
Sodium-dependent noradrenaline transporter 08210
Sodium-dependent dopamine transporter0404
Histamine H2 receptor0606
D(1B) dopamine receptor0404
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A0808
5-hydroxytryptamine receptor 1B0505
Trypanothione reductase0404
D(4) dopamine receptor0404
5-hydroxytryptamine receptor 2B0404
Histamine H1 receptor0112
Sodium-dependent serotonin transporter0628
Melanocortin receptor 40202
5-hydroxytryptamine receptor 7 0101
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0306
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0505
Mu-type opioid receptor07311
Glutamate receptor ionotropic, NMDA 1 0101
D(3) dopamine receptor0708
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0719
Kappa-type opioid receptor0719
5-hydroxytryptamine receptor 2B0606
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0808
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor3003
5-hydroxytryptamine receptor 60606
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein5117
Proteasome subunit alpha type-60012
D(2) dopamine receptor0607
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 0617
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0303
Potassium voltage-gated channel subfamily H member 20707
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2D0101
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0101
D0202
Sodium channel protein type 2 subunit alpha0101
Proteasome subunit beta type-70001
Ataxin-24004
Sigma non-opioid intracellular receptor 10909
Angiotensin-converting enzyme 2 0112
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0202
Sodium channel protein type 10 subunit alpha0101
interleukin 83003
Solute carrier family 22 member 10101
Solute carrier family 22 member 20304
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
ATP-dependent translocase ABCB10404
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10404
Potassium-transporting ATPase subunit beta0101
Solute carrier family 22 member 60202
Solute carrier family 22 member 10202
Multidrug and toxin extrusion protein 20202
Solute carrier family 22 member 80304
Multidrug and toxin extrusion protein 10303
Histamine H4 receptor0202
Solute carrier family 22 member 110101
Solute carrier family 22 member 20303
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
SMAD family member 22002
GALC protein1001
SMAD family member 32002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
nuclear receptor subfamily 1, group I, member 23003
nuclear factor erythroid 2-related factor 2 isoform 23003
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Solute carrier family 22 member 30101
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
TAR DNA-binding protein 434004
Chain A, Beta-lactamase1001
Motilin receptor0011
acid sphingomyelinase2002
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK11001
streptokinase A precursor0022
Motilin receptor0112
Rap guanine nucleotide exchange factor 31001
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
60 kDa heat shock protein, mitochondrial0101
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
10 kDa heat shock protein, mitochondrial0101
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Cytochrome P450 1B10202
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0101
50S ribosomal protein L36 20213
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Luciferase5005
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0304
Delta-type opioid receptor0416
Mu-type opioid receptor05210
Kappa-type opioid receptor0315
Kappa-type opioid receptor0404
Mu-type opioid receptor0316
Mu-type opioid receptor0505
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10202
regulator of G-protein signaling 44004
NPC intracellular cholesterol transporter 1 precursor1001
huntingtin isoform 22002
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Sodium-dependent noradrenaline transporter0101
Sodium channel protein type 1 subunit alpha0101
Cytochrome P450 2C80101
Dipeptidyl peptidase 40101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Acetylcholinesterase0101
Acetylcholinesterase0505
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0303
Cytochrome P450 2C190101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gastrin/cholecystokinin type B receptor 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0101
Beta-2 adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0101
Chain A, Dihydrofolate reductase0011
Chain A, Ferritin light chain2002
glp-1 receptor, partial4004
glucocerebrosidase1001
lysosomal alpha-glucosidase preproprotein2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Alpha-synuclein3205
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0101
nonstructural protein 11001
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
snurportin-11001
muscleblind-like protein 1 isoform 13003
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Dihydrofolate reductase0101
Fatty acid-binding protein, liver0101
Albumin0102
Cholinesterase0303
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0203
UDP-glucuronosyltransferase 2B70001
Prostaglandin G/H synthase 10101
Adenosine receptor A10101
Caspase-10101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin G/H synthase 2 0203
UDP-glucuronosyltransferase 1A30002
Aldo-keto reductase family 1 member C30101
Caspase-30101
Solute carrier organic anion transporter family member 1A10101
Caspase-40101
4-aminobutyrate aminotransferase, mitochondrial0101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Prostaglandin G/H synthase 20202
Fatty-acid amide hydrolase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0203
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Dehydrogenase/reductase SDR family member 90101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Chain E, Fibrin beta chain0101
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
hypoxia-inducible factor 1 alpha subunit3003
Caspase 6, apoptosis-related cysteine peptidase0001
PPM1D protein2002
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase1001
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial1001
luciferase1001
bromodomain adjacent to zinc finger domain 2B2002
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
thyroid hormone receptor beta isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
Vpr1001
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Amyloid-beta precursor protein0101
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Cruzipain0101
Guanine nucleotide-binding protein G1001
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
ATPase family AAA domain-containing protein 51001
Zinc finger protein mex-50011
phosphoglycerate kinase1001
5-hydroxytryptamine receptor 3E0011
5-hydroxytryptamine receptor 3B0011
Myeloperoxidase0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 3A0011
6-phosphogluconate dehydrogenase, decarboxylating0101
Lactoperoxidase0101
5-hydroxytryptamine receptor 4 0102
5-hydroxytryptamine receptor 3D0011
5-hydroxytryptamine receptor 3C0011
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0202
Opioid receptor, delta 1b 0101
Acetylcholinesterase0202
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Translocator protein0011
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Kappa-type opioid receptor0214
Nociceptin receptor0101
Mu-type opioid receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Cholinesterase0101
Neutrophil elastase0101
Nitric oxide synthase, endothelial0101
Collagenase 30101
Sodium/iodide cotransporter0101
15-lipoxygenase, partial2002
Solute carrier family 22 member 30101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Indoleamine 2,3-dioxygenase 10101
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Indoleamine 2,3-dioxygenase 20101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
apical membrane antigen 1, AMA11001
polyunsaturated fatty acid lipoxygenase ALOX121001
rac GTPase-activating protein 1 isoform a0101
Adenosine receptor A30202
Cannabinoid receptor 10202
cytochrome P450 2C9 precursor1001
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
dopamine D1 receptor1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Protein-arginine deiminase type-40303
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]