Gastric Volvulus

Twisting of the STOMACH that may result in gastric ISCHEMIA and GASTRIC OUTLET OBSTRUCTION. It is often associated with DIAPHRAGMATIC HERNIA.

Synonym
Volvulus, Stomach
Stomach Volvulus
Gastric Volvulus

Excerpt	Reference
"Gastric volvulus is a rare surgical emergency in infancy and childhood."	( Cameron, AE; Howard, ER, 1987)
"Gastric volvulus is an uncommon foregut condition."	( Adejuyigbe, S; Adetiloye, B; Lawal, D; Oluwole, S, 1997)
"Gastric volvulus is an uncommon condition, which can be difficult to diagnose and treat."	( Ackroyd, R; Devitt, PG; Teague, WJ; Watson, DI, 2000)
"Gastric volvulus is an infrequently encountered clinical entity characterized by abnormal rotation of the stomach."	( Horiuchi, T; Inoue, M; Shono, Y; Tabuse, K; Tsuji, T, 2007)
"Intrathoracic gastric volvulus is extremely rare in the newborn period."	( Antonuccio, P; Arena, F; Impellizzeri, P; Montalto, S; Racchiusa, S; Romeo, C, 2009)
"Gastric volvulus is a clinically significant cause of acute or recurrent abdominal pain and chronic vomiting in children."	( Morabito, G; Romano, C; Salamone, I; Trecroci, I, 2016)
"Gastric volvulus is an extremely rare disorder in the pediatric population."	( Morabito, G; Romano, C; Salamone, I; Trecroci, I, 2016)
"Gastric volvulus is an uncommon, but severe pathology requiring early diagnosis and urgent treatment."	( Somville, F; Van der Mieren, G; Van Olmen, D, 2018)

Excerpt	Reference
"Acute and chronic gastric volvulus can be treated successfully by either open or laparoscopic surgery."	( Ackroyd, R; Devitt, PG; Teague, WJ; Watson, DI, 2000)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	30 (32.61)	23.3326
1990's	16 (17.39)	12.5806
2000's	23 (25.00)	18.1394
2010's	19 (20.65)	28.8240
2020's	4 (4.35)	9.53

Drug	Relationship Strength	Studies	Trials
chlorine	low	2	0
lactic acid	low	8	0
dimethyl sulfoxide	low	1	0
hydrogen carbonate	low	2	0
1-anilino-8-naphthalenesulfonate	low	1	0
deferoxamine	low	1	0
valproic acid	low	1	0
lidocaine	medium	3	1
procainamide	low	1	0
sulfasalazine	low	1	0
sucrose	low	1	0
lactose	low	1	0
diatrizoate meglumine	low	1	0
erythromycin	low	2	0
streptomycin	low	2	0
octyl 2-cyanoacrylate	medium	1	1
technetium	low	2	0
barium sulfate	low	24	0
quinidine gluconate	low	1	0
u 74006f	low	1	0
imatinib mesylate	low	1	0
glucosamine	low	1	0
elastin	low	1	0
quinidine	low	1	0
metrizamide	low	1	0
cocaine	low	1	0
l 743,872	low	1	0
sodium bicarbonate	low	1	0
sodium acetate, anhydrous	medium	1	1
lithium	low	1	0
bilirubin	low	1	0
11-dehydro-thromboxane b2	low	1	0
thromboxane b2	low	1	0
naloxone	low	1	0
barium	low	3	0
pentagastrin	low	1	0
gastrins	low	2	0
sodium pertechnetate tc 99m	low	1	0
cardiovascular agents	low	1	0
natriuretic peptide, brain	low	1	0
ascorbic acid	low	2	0
technetium tc 99m medronate	low	1	0
folic acid	low	1	0
allopurinol	low	1	0

Protein Targets (522)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	4	0	0	4
USP1 protein, partial	4	0	0	4
TDP1 protein	9	0	0	9
vitamin D3 receptor isoform VDRA	3	0	0	3
importin subunit beta-1 isoform 1	2	0	0	2
flap endonuclease 1	3	0	0	3
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	3	0	0	3
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	9	0	0	9
DNA polymerase kappa isoform 1	2	0	0	2
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	1	2
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
aldehyde dehydrogenase 1 family, member A1	8	0	0	8
interleukin 8	1	0	0	1
AR protein	11	0	0	11
thyroid stimulating hormone receptor	5	0	0	5
estrogen receptor 2 (ER beta)	3	0	0	3
progesterone receptor	3	0	0	3
glucocorticoid receptor [Homo sapiens]	6	0	0	6
estrogen-related nuclear receptor alpha	10	0	0	10
estrogen nuclear receptor alpha	13	0	0	13
IDH1	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	5	0	0	5
Bloom syndrome protein isoform 1	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
thyroid hormone receptor beta isoform 2	7	0	0	7
ras-related protein Rab-9A	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	7	0	0	7
survival motor neuron protein isoform d	2	0	0	2
lamin isoform A-delta10	6	0	0	6
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	8
Polyphenol oxidase 2	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	2	0	0	2
Bile salt export pump	0	11	0	11
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	5	0	0	5
Glutamate receptor 2	2	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	2	0	0	2
Canalicular multispecific organic anion transporter 1	0	6	0	6
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	4	0	0	4
RAR-related orphan receptor gamma	5	0	0	5
GLI family zinc finger 3	8	0	0	8
thioredoxin glutathione reductase	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	4	0	0	4
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
chromobox protein homolog 1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	1	0	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Spike glycoprotein	4	0	0	4
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, Cruzipain	1	0	0	1
phosphopantetheinyl transferase	1	0	0	1
Microtubule-associated protein tau	3	0	0	3
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Solute carrier organic anion transporter family member 1B1	0	4	0	5
Carbonic anhydrase 1	0	6	0	6
Carbonic anhydrase 2	0	7	1	8
Carbonic anhydrase 4	0	4	0	4
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 15	0	2	0	2
Luciferase	5	0	0	5
aryl hydrocarbon receptor	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	4	0	0	4
nuclear receptor ROR-gamma isoform 1	1	0	0	1
peripheral myelin protein 22	2	0	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	3
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	2	0	2
apical membrane antigen 1, AMA1	1	0	0	1
67.9K protein	1	0	0	1
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Hsf1 protein	0	0	1	1
Cereblon isoform 4	0	2	0	2
retinoid X nuclear receptor alpha	4	0	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Chain A, Beta-lactamase	4	0	0	4
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	1	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
30S ribosomal protein S6	0	1	1	2
30S ribosomal protein S7	0	1	1	2
50S ribosomal protein L15	0	1	1	2
Albumin	0	0	1	1
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	4	1	6
Cytochrome P450 3A4	0	2	0	3
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	1	1	2
50S ribosomal protein L11	0	1	1	2
50S ribosomal protein L7/L12	0	1	1	2
50S ribosomal protein L19	0	1	1	2
50S ribosomal protein L1	0	1	1	2
50S ribosomal protein L20	0	1	1	2
50S ribosomal protein L27	0	1	1	2
50S ribosomal protein L28	0	1	1	2
50S ribosomal protein L29	0	1	1	2
50S ribosomal protein L31	0	1	1	2
50S ribosomal protein L31 type B	0	1	1	2
50S ribosomal protein L32	0	1	1	2
50S ribosomal protein L33	0	1	1	2
50S ribosomal protein L34	0	1	1	2
50S ribosomal protein L35	0	1	1	2
50S ribosomal protein L36	0	1	1	2
30S ribosomal protein S10	0	1	1	2
30S ribosomal protein S11	0	1	1	2
30S ribosomal protein S12	0	1	1	2
30S ribosomal protein S13	0	1	1	2
30S ribosomal protein S16	0	1	1	2
30S ribosomal protein S18	0	1	1	2
30S ribosomal protein S19	0	1	1	2
30S ribosomal protein S20	0	1	1	2
30S ribosomal protein S2	0	1	1	2
30S ribosomal protein S3	0	1	1	2
30S ribosomal protein S4	0	1	1	2
30S ribosomal protein S5	0	1	1	2
30S ribosomal protein S8	0	1	1	2
30S ribosomal protein S9	0	1	1	2
50S ribosomal protein L13	0	1	1	2
50S ribosomal protein L14	0	1	1	2
50S ribosomal protein L16	0	1	1	2
50S ribosomal protein L23	0	1	1	2
30S ribosomal protein S15	0	1	1	2
50S ribosomal protein L17	0	1	1	2
50S ribosomal protein L21	0	1	1	2
50S ribosomal protein L30	0	1	1	2
50S ribosomal protein L6	0	1	1	2
30S ribosomal protein S14	0	1	1	2
30S ribosomal protein S17	0	1	1	2
30S ribosomal protein S1	0	1	1	2
50S ribosomal protein L18	0	1	1	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Cytochrome P450 2C9	0	4	0	4
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 2J2	0	3	0	3
50S ribosomal protein L2	0	1	1	2
50S ribosomal protein L3	0	1	1	2
50S ribosomal protein L24	0	1	1	2
50S ribosomal protein L4	0	1	1	2
50S ribosomal protein L22	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
50S ribosomal protein L5	0	1	1	2
30S ribosomal protein S21	0	1	1	2
50S ribosomal protein L25	0	1	1	2
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
50S ribosomal protein L36 2	0	1	1	2
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Multidrug and toxin extrusion protein 1	0	3	0	3
ATAD5 protein, partial	2	0	0	2
glycogen synthase kinase-3 alpha	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
Chain A, Dihydrofolate reductase	0	0	1	1
Chain A, Ferritin light chain	1	0	0	1
glp-1 receptor, partial	3	0	0	3
glucocerebrosidase	1	0	0	1
alpha-galactosidase	1	0	0	1
activating transcription factor 6	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
DNA polymerase beta	1	0	0	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Alpha-synuclein	1	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	4	0	0	4
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	4	0	0	4
peroxisome proliferator-activated receptor delta	1	0	0	1
thyroid stimulating hormone receptor	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Cytochrome P450 2C8	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	0	0	1
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
cytochrome P450 2D6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
GLS protein	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
cytochrome P450 3A4 isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	2	0	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit delta	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	2	0	0	2
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	2	0	0	2
Sodium channel protein type 4 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-2	2	0	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	2	0	2
Potassium channel subfamily K member 18	0	1	0	1
GABA theta subunit	2	0	0	2
Gamma-aminobutyric acid receptor subunit epsilon	2	0	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Cytochrome P450 2D6	0	3	0	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Histidine decarboxylase	0	0	1	1
D(3) dopamine receptor	0	1	0	1
Adenosine receptor A1	0	1	0	1
Delta-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	2	4
Kappa-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	3	2	5
Kappa-type opioid receptor	0	1	2	3
Mu-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	2	2	5
Mu-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	0	1	1
Gastrin/cholecystokinin type B receptor	0	1	1	2
cytochrome P450 2C19 precursor	1	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	3	0	5
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Solute carrier family 22 member 1	0	4	0	5
Solute carrier family 22 member 2	0	4	0	4
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
peroxisome proliferator activated receptor gamma	3	0	0	3
Histone H2A.x	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cholinesterase	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Cholinesterase	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
Free fatty acid receptor 3	0	0	1	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Carbonic anhydrase 9	0	3	1	4
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
Bile salt export pump	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
G	1	0	0	1
Replicase polyprotein 1ab	0	0	1	1
cytochrome P450 2C9 precursor	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Tumor necrosis factor	0	0	1	1
Interferon beta	1	0	0	1
HLA class I histocompatibility antigen, B alpha chain	1	0	0	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Androgen receptor	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Caspase-1	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	1	0	1
Histamine H2 receptor	1	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Sodium/bile acid cotransporter	0	1	0	1
Inositol hexakisphosphate kinase 1	1	0	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
cytochrome P450 2C9, partial	1	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Epidermal growth factor receptor	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Histamine H2 receptor	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
pregnane X receptor	1	0	0	1
thyroid hormone receptor beta isoform a	1	0	0	1
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (92)

Protein Targets (522)

Gastric Volvulus

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (92)

Drugs Studied (59)

Protein Targets (522)