Siderosis

A form of pneumoconiosis resulting from inhalation of iron in the mining dust or welding fumes.

Synonym
Siderosis

Excerpt	Reference
"Siderosis is a process with a chronic course."	( Neubauer, H, 1979)
"Superficial siderosis is associated with chronic blood loss into the cerebrospinal fluid."	( Maurizi, CP, 1996)
"Superficial siderosis is characterized by the deposition of hemosiderin in the leptomeninges, cranial nerves and spinal cord."	( Kato, K; Mizoi, K; Sasajima, H; Takahashi, S; Tomura, N; Watarai, J, 1998)
"Superficial siderosis is a neurodegenerative disease caused by toxic accumulation of hemosiderin on the surface of the brain and spinal cord for which there is no known effective treatment."	( Levy, M; Llinas, R, 2012)
"Superficial siderosis is caused by recurrent haemorrhage in the subarachnoid space leading to haemosiderin deposition."	( Baguley, D; Crundwell, G; Cummins, G; Lennox, G, 2013)
"Siderosis is a disease characterized by the accumulation of iron in various tissues."	( Bayram, I; Bilgili, SG; Karadag, AS; Ozlu, E, 2014)
"Ocular siderosis is a rare sight-threatening complication that occurs after a penetrating ocular injury by an iron-containing foreign body."	( Acikel, C; Erdem, O; Gunal, A; Mumcuoglu, T; Ozge, G; Soykut, B, 2015)
"Ocular siderosis is a rare but severe complication of open globe trauma with intraocular retention of a metallic foreign body."	( Balouch, L; Bamou, Y; El Boukhrissi, F; Hommadi, A; Laktaoui, A, 2017)
"Ocular siderosis is induced by a retained intraocular foreign body (IOFB) containing iron and can present as siderotic glaucoma."	( Huang, Y; Li, Z; Ye, Z, 2020)
"Superficial siderosis is a rare neurodegenerative disease caused by hemosiderin deposition on the brain surface."	( Nose, Y; Sanjo, N; Sasaki, M; Tateishi, U; Uwano, I; Yokota, T, 2022)
"Superficial siderosis is a consequence of repetitive bleeding into the subarachnoid space, leading to toxic iron and hemosiderin deposits on the surface of the brain and spine."	( Armbrust, M; Foerch, C; Friedauer, L; Harter, PN; Hattingen, E; Neuhaus, E; Steidl, E; Steinbach, J; Urban, H; von Brauchitsch, S, 2023)

Excerpt	Reference
"Hepatic siderosis has a synergistic effect with hexachlorobenzene on this enzyme and may exert additional effects by promoting cytochrome P 450 turnover."	( Carstens, M; Louw, M; Neethling, AC; Percy, VA; Shanley, BC, 1977)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	366 (65.71)	23.3326
1990's	65 (11.67)	12.5806
2000's	56 (10.05)	18.1394
2010's	50 (8.98)	28.8240
2020's	20 (3.59)	9.53

Drug	Relationship Strength	Studies	Trials
acetaldehyde	low	1	0
ammonium hydroxide	low	1	0
carbon monoxide	low	1	0
choline	low	1	0
chlorine	low	1	0
dimethyl sulfoxide	low	1	0
glycerol	low	1	0
iodine	low	1	0
thioctic acid	low	2	0
nickel	low	4	0
orotic acid	low	1	0
parathion	low	1	0
pyridoxine	low	1	0
amlodipine	low	1	0
carbamazepine	low	2	0
chloroquine	low	1	0
deferiprone	medium	13	2
deferoxamine	medium	81	3
pentetic acid	low	4	0
dimercaprol	low	1	0
harmaline	low	1	0
indomethacin	low	1	0
isoniazid	medium	4	1
2-propanol	low	8	0
aminosalicylic acid	medium	1	1
pyrimethamine	low	1	0
safrole	low	1	0
sulfobromophthalein	low	1	0
ticlopidine	low	1	0
trientine	low	1	0
urethane	low	1	0
prednisolone	low	5	0
lysergic acid diethylamide	low	1	0
sorbitol	low	2	0
thyroxine	low	1	0
aldosterone	low	1	0
penicillamine	low	2	0
prednisone	low	2	0
2-acetylaminofluorene	low	1	0
carbon tetrachloride	low	3	0
chloramphenicol	low	1	0
cyanides	low	1	0
levodopa	low	1	0
edetic acid	low	5	0
p-dimethylaminoazobenzene	low	1	0
tyrosine	low	1	0
adenosine monophosphate	low	1	0
leucine	low	1	0
methionine	low	1	0
desoxycorticosterone	low	1	0
cycloheximide	low	1	0
phencyclidine	low	25	0
methylmethacrylate	low	1	0
methylprednisolone	low	2	0
diethylenetriamine	low	1	0
hexachlorobenzene	low	1	0
meglumine	low	1	0
benzoxazoles	low	1	0
thiazoles	low	1	0
limestone	low	1	0
cyanogen bromide	low	1	0
copper gluconate	low	1	0
ethambutol	low	1	0
d-alpha tocopherol	low	3	0
amiloride	low	1	0
streptomycin	medium	2	1
manganese	low	2	0
silver	low	2	0
technetium	low	1	0
titanium	low	1	0
cadmium	low	1	0
chromium	low	4	0
uranium	low	1	0
ferrous sulfate	low	4	0
chlorine	low	2	0
trolamine salicylate	low	1	0
ethionine	low	1	0
levamisole	low	2	0
fluorides	low	1	0
phenyl acetate	low	2	0
4-methoxyamphetamine	low	1	0
transferrin	low	31	0
glucaric acid	low	2	0
oxcarbazepine	low	1	0
zidovudine	low	2	0
ribavirin	medium	1	1
chlorodiphenyl (54% chlorine)	low	1	0
propiconazole	low	7	0
clopidogrel	low	1	0
triazoles	medium	3	1
glycidyl nitrate	low	1	0
cobalt	low	1	0
cyanates	low	1	0
beta-n-methylamino-l-alanine	low	1	0
hydroxyl radical	low	2	0
deferasirox	medium	3	1
cortisone	low	1	0
ibogaine	low	1	0
glycogen	low	1	0
fibrin	low	1	0
retinol	low	1	0
ferulic acid	low	1	0
diethylstilbestrol	low	1	0
ferlixit	low	1	0
thiourea	low	1	0
ferric ferrocyanide	low	1	0
nadp	low	1	0
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole	low	1	0
quinine	low	1	0
cystine	low	1	0
bilirubin	low	3	0
morphine	low	1	0
lead	low	1	0
barium	low	2	0
aluminum	low	5	0
sulfur	low	2	0
beryllium	low	2	0
cysteine	low	2	0
phosphorus	low	4	0
oxalates	medium	2	1
ferrous fumarate	low	1	0
gadolinium dtpa	low	2	0
apixaban	low	1	0
acebutolol	low	1	0
tafamidis	low	1	0
losartan potassium	low	2	0
acid phosphatase	low	1	0
nad	low	2	0
florbetapir f 18	low	1	0
natriuretic peptide, brain	medium	1	1
heme	low	8	0
ascorbic acid	medium	13	1
teferrol	low	1	0
ferric oxide, saccharated	low	2	0
lactoferrin	low	3	0
thromboplastin	low	1	0
levoleucovorin	low	1	0
folic acid	low	1	0
allopurinol	low	1	0
trypan blue	low	1	0
chromazurol b	low	1	0
eye	low	15	0
ferric carboxymaltose	low	1	0
carbidopa	low	1	0
technetium tc 99m bicisate	low	1	0

Protein Targets (942)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	4	0	0	4
thioredoxin reductase	8	0	0	8
USP1 protein, partial	14	0	0	14
TDP1 protein	31	0	0	31
vitamin D3 receptor isoform VDRA	12	0	0	12
importin subunit beta-1 isoform 1	4	0	0	4
flap endonuclease 1	7	0	0	7
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	29	0	0	29
DNA polymerase kappa isoform 1	14	0	0	14
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	2	2	5
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	2	1	3
Cyclin-dependent kinase 2	0	1	1	2
Choline O-acetyltransferase	0	2	0	2
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Amyloid-beta precursor protein	0	6	0	6
Luciferase	12	0	0	12
RAR-related orphan receptor gamma	29	0	0	29
AR protein	41	0	0	41
estrogen receptor 2 (ER beta)	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	21	0	0	21
progesterone receptor	20	0	0	20
glucocorticoid receptor [Homo sapiens]	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	33	0	0	33
estrogen-related nuclear receptor alpha	32	0	0	32
pregnane X nuclear receptor	23	0	0	23
estrogen nuclear receptor alpha	45	0	0	45
aryl hydrocarbon receptor	15	0	0	15
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
thyroid stimulating hormone receptor	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
thyroid hormone receptor beta isoform 2	30	0	0	30
histone deacetylase 9 isoform 3	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	33	0	0	33
5-hydroxytryptamine receptor 4	0	4	0	4
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Cytochrome P450 1A2	0	3	0	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Alpha-2A adrenergic receptor	0	9	1	10
Glutamate receptor 2	18	0	0	18
Amine oxidase [flavin-containing] A	0	4	0	4
Sodium-dependent noradrenaline transporter	0	4	0	4
5-hydroxytryptamine receptor 2C	0	5	0	5
Sodium-dependent serotonin transporter	0	6	1	7
5-hydroxytryptamine receptor 2B	0	5	0	5
ATPase family AAA domain-containing protein 5	12	0	0	12
Ataxin-2	14	0	0	14
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
GLI family zinc finger 3	30	0	0	30
aldehyde dehydrogenase 1 family, member A1	26	0	0	26
retinoid X nuclear receptor alpha	23	0	0	23
peroxisome proliferator-activated receptor delta	17	0	0	17
activating transcription factor 6	13	0	0	13
v-jun sarcoma virus 17 oncogene homolog (avian)	16	0	0	16
Histone H2A.x	10	0	0	10
thyroid hormone receptor beta isoform a	11	0	0	11
heat shock protein beta-1	11	0	0	11
lamin isoform A-delta10	20	0	0	20
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 2A	0	3	2	5
5-hydroxytryptamine receptor 1A	0	3	1	4
5-hydroxytryptamine receptor 1B	0	1	1	2
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
acetylcholinesterase	12	0	0	12
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
caspase 7, apoptosis-related cysteine protease	4	0	0	4
thyroid stimulating hormone receptor	15	0	0	15
farnesoid X nuclear receptor	11	0	0	11
peroxisome proliferator activated receptor gamma	22	0	0	22
vitamin D (1,25- dihydroxyvitamin D3) receptor	21	0	0	21
caspase-3	4	0	0	4
thyrotropin-releasing hormone receptor	1	0	0	1
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Cellular tumor antigen p53	26	0	0	26
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
regulator of G-protein signaling 4	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	24	0	0	24
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	2	0	2
Alcohol dehydrogenase S chain	0	2	0	2
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	4
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	5	0	5
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
5'-nucleotidase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	3	1	4
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	2	4
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
ATP-dependent phosphofructokinase	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	0	3	3	6
Androgen receptor	0	5	0	5
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	2
interleukin 8	7	0	0	7
IDH1	10	0	0	10
Bloom syndrome protein isoform 1	7	0	0	7
transcriptional regulator ERG isoform 3	1	0	0	1
ras-related protein Rab-9A	3	0	0	3
survival motor neuron protein isoform d	7	0	0	7
ATP-binding cassette sub-family C member 3	0	18	0	18
Multidrug resistance-associated protein 4	0	18	0	19
Polyphenol oxidase 2	0	4	0	6
Bile salt export pump	0	30	0	30
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	4	1	5
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Canalicular multispecific organic anion transporter 1	0	16	0	16
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	14	0	0	14
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
glucocerebrosidase	3	0	0	3
arylsulfatase A	4	0	0	4
alpha-galactosidase	4	0	0	4
cytochrome P450 2D6 isoform 1	6	0	0	6
lysosomal alpha-glucosidase preproprotein	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
huntingtin isoform 2	2	0	0	2
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	5	0	6
Prothrombin	0	2	0	2
Coagulation factor X	0	3	0	3
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	3
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	4	0	6
Solute carrier family 22 member 2	0	5	0	6
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Microtubule-associated protein tau	12	0	0	12
thioredoxin glutathione reductase	3	0	0	3
Smad3	6	0	0	6
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Carbonic anhydrase 1	0	10	0	12
Carbonic anhydrase 2	0	11	0	13
Tyrosine-protein phosphatase non-receptor type 1	0	0	1	1
Chain A, Ferritin light chain	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	19	0	0	19
G	9	0	0	9
cytochrome P450 2D6	10	0	0	10
chromobox protein homolog 1	12	0	0	12
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	13	0	0	13
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium channel subfamily K member 2	0	2	1	3
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
ATP-dependent translocase ABCB1	0	5	0	6
Alpha-2C adrenergic receptor	0	7	0	7
Alpha-2B adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 6	0	5	0	5
Spike glycoprotein	13	1	3	17
Sodium-dependent dopamine transporter	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium channel subfamily K member 2	0	1	0	1
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
EWS/FLI fusion protein	11	0	0	11
Coagulation factor X	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	7	0	0	7
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	3	0	4
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	5	1	6
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Chain A, Cruzipain	4	0	0	4
phosphopantetheinyl transferase	13	0	0	13
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Chain A, Beta-lactamase	4	0	0	4
mitogen-activated protein kinase 1	6	0	0	6
Vpr	1	0	0	1
Bile salt export pump	0	6	0	6
Albumin	0	0	1	1
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	3
Cytochrome P450 2B6	0	4	1	5
Sodium channel protein type 4 subunit alpha	0	1	0	2
Cytochrome P450 2J2	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	2	0	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
pregnane X receptor	9	0	0	9
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Cytochrome P450 2E1	0	1	0	1
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Cytochrome P450 3A4	0	6	1	7
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase 4	0	7	0	9
Carbonic anhydrase	0	3	0	5
Carbonic anhydrase 15	0	6	0	8
PPM1D protein	3	0	0	3
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	3	4
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	3	5
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	1	3	4
Muscarinic acetylcholine receptor M1	0	3	0	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	0	5
Angiotensin-converting enzyme 2	0	1	3	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
muscarinic acetylcholine receptor M1	5	0	0	5
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	1	0	3
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	7	1	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
nonstructural protein 1	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
Cytochrome P450 2C8	0	3	0	3
Liver carboxylesterase 1	0	0	0	1
Cytochrome P450 2C19	0	4	0	4
Rap guanine nucleotide exchange factor 4	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
endonuclease IV	2	0	0	2
dopamine D1 receptor	3	0	0	3
GLS protein	6	0	0	6
peripheral myelin protein 22 isoform 1	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
cytochrome P450 3A4 isoform 1	12	0	0	12
M-phase phosphoprotein 8	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	12	0	0	12
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Gamma-aminobutyric acid receptor subunit beta-1	12	0	0	12
Gamma-aminobutyric acid receptor subunit delta	12	0	0	12
Gamma-aminobutyric acid receptor subunit gamma-2	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-5	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-3	12	0	0	12
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-2	12	0	0	12
Glycine receptor subunit alpha-3	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	12	0	0	12
Gamma-aminobutyric acid receptor subunit gamma-3	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-6	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-1	12	0	0	12
Gamma-aminobutyric acid receptor subunit beta-3	12	0	0	12
Gamma-aminobutyric acid receptor subunit beta-2	12	0	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
GABA theta subunit	12	0	0	12
Multidrug and toxin extrusion protein 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	12	0	0	12
glp-1 receptor, partial	6	0	0	6
ATAD5 protein, partial	4	0	0	4
Fumarate hydratase	4	0	0	4
polyprotein	4	0	0	4
67.9K protein	8	0	0	8
P53	1	0	0	1
RPL19A	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Alpha-synuclein	3	2	0	5
Nuclear receptor ROR-gamma	10	0	0	10
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	1	5
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	2
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Lysine-specific demethylase 6B	0	1	0	1
Lysine-specific demethylase 4A	0	3	1	4
Lysine-specific demethylase 5A	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
apical membrane antigen 1, AMA1	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
cytochrome P450 2C9 precursor	2	0	0	2
Lysine-specific demethylase 6A	0	1	0	1
Lysine-specific demethylase 5C	0	1	0	1
Histamine H2 receptor	6	0	0	6
Lysine-specific demethylase 2B	0	1	0	1
Deoxyhypusine hydroxylase	0	2	0	2
Lysine-specific demethylase 2A	0	1	0	1
Methylcytosine dioxygenase TET2	0	1	0	1
GALC protein	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Solute carrier family 22 member 3	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
hypothetical protein, conserved	1	0	0	1
Carbonic anhydrase 12	0	3	0	5
Carbonic anhydrase 3	0	3	0	5
Carbonic anhydrase 6	0	3	0	5
Carbonic anhydrase 5A, mitochondrial	0	4	0	6
Carbonic anhydrase 7	0	3	0	5
Carbonic anhydrase 9	0	4	0	6
Carbonic anhydrase 13	0	3	0	4
Carbonic anhydrase 14	0	3	0	5
Carbonic anhydrase 5B, mitochondrial	0	3	0	5
15-lipoxygenase, partial	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
peripheral myelin protein 22	9	0	0	9
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
neuropeptide S receptor isoform A	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Nuclear receptor subfamily 1 group I member 2	0	1	4	5
Estrogen receptor	0	4	1	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Integrin beta-3	2	0	0	2
Tyrosine-protein kinase Fyn	0	2	0	2
Integrin alpha-IIb	2	0	0	2
Beta-1 adrenergic receptor	0	3	0	3
Adenosine receptor A3	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
D(2) dopamine receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	2	0	2
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Thromboxane-A synthase	0	2	0	2
5-hydroxytryptamine receptor 2A	0	3	1	4
Mu-type opioid receptor	0	4	1	6
D(3) dopamine receptor	0	3	0	3
Vasopressin V1a receptor	0	2	0	2
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	4	1	6
Alpha-1A adrenergic receptor	0	2	0	2
Estrogen-related receptor gamma	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Aldehyde oxidase	0	1	0	1
UDP-glucose 4-epimerase	0	1	0	1
Estrogen receptor beta	0	4	1	5
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Cysteinyl leukotriene receptor 1	0	2	0	2
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	4
Pantothenate synthetase	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
ClpP	1	0	0	1
Acetylcholinesterase	0	5	0	5
Cholinesterase	0	2	0	2
Pyruvate kinase PKM	0	1	1	2
Adenosine receptor A1	0	2	0	4
Adenosine receptor A2a	0	2	0	4
Alpha-glucosidase MAL12	0	1	0	1
Cholinesterase	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Hyaluronidase-1	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Integrase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
DNA polymerase beta	3	0	0	3
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	5
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	4
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
STE24	0	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
5-hydroxytryptamine receptor 5A	0	2	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	2
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Albumin	0	1	4	6
Prostaglandin G/H synthase 1	0	2	0	3
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	3	1	4
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 7	0	0	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Acetylcholinesterase	0	0	1	1
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	4
Proton-coupled amino acid transporter 1	0	2	0	3
Phospholipase A-2-activating protein	0	2	0	2
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	4
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	4
Glutamate receptor ionotropic, NMDA 2B	0	2	0	4
Glutamate receptor ionotropic, NMDA 2C	0	2	0	5
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	0	4
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	4
Monocarboxylate transporter 10	0	0	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	4
phosphoglycerate kinase	1	0	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	1	0	1
D	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	1	1	2
Muscarinic acetylcholine receptor M4	0	1	1	2
Muscarinic acetylcholine receptor M5	0	1	1	2
Muscarinic acetylcholine receptor M2	0	1	1	2
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	1	0	3
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	5
Mu-type opioid receptor	0	2	1	6
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	6
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	1	0	1
BRCA1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
C-terminal-binding protein 1	1	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	0	1	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Pyridoxal kinase	0	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	1	1	2
Beta-lactoglobulin	0	0	1	1
NS5	0	0	1	1
Thrombopoietin	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Hematopoietic prostaglandin D synthase	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
Urease subunit alpha	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Diamine acetyltransferase 1	0	0	0	1
Thialysine N-epsilon-acetyltransferase	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
Thymidine kinase, cytosolic	0	2	0	3
Protein kinase C beta type	0	1	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Thymidine kinase	0	1	0	2
Reverse transcriptase/RNaseH	0	1	2	6
Solute carrier family 22 member 11	0	0	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (557)

Protein Targets (942)

Siderosis

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (557)

Drugs Studied (173)

Protein Targets (942)