Anthracosis

A diffuse parenchymal lung disease caused by accumulation of inhaled CARBON or coal dust. The disease can progress from asymptomatic anthracosis to massive lung fibrosis. This lung lesion usually occurs in coal MINERS, but can be seen in urban dwellers and tobacco smokers.

Synonym
Coal Worker's Pneumoconiosis
Black Lung Disease
Coalworker's Pneumoconiosis
Pneumoconiosis, Coal Worker's
Coal Miner's Lung
Anthracosis
Black Lung

Excerpt	Reference
"Anthracosis is a kind of pneumoconiosis that may cause parenchymal and bronchiolar injury and mediastinal lymphadenopathy."	( Alpaydın, AÖ; Güler, N; Karaçam, V; Özdoğan, Ö; Tertemiz, KC; Ulukuş, Ç, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	12 (9.30)	23.3326
1990's	0 (0.00)	12.5806
2000's	12 (9.30)	18.1394
2010's	78 (60.47)	28.8240
2020's	27 (20.93)	9.53

Drug	Relationship Strength	Studies	Trials
choline	low	1	0
methanol	low	2	0
pyrazinamide	low	1	0
atrazine	low	1	0
isoniazid	low	2	0
isoproterenol	low	1	0
aminosalicylic acid	low	1	0
phencyclidine	low	82	0
limestone	low	1	0
malondialdehyde	low	1	0
ethambutol	low	1	0
streptomycin	low	1	0
gold	low	1	0
4-methoxyamphetamine	low	1	0
gallium citrate	low	1	0
captopril	low	1	0
simvastatin	medium	1	1
goralatide	low	1	0
fluorodeoxyglucose f18	low	9	0
nicotine	low	1	0
imipenem, anhydrous	low	4	0
angiotensin ii, des-phe(8)-	low	1	0
hydroxyl radical	low	1	0
angiotensin ii	low	1	0
fluorocholine	low	1	0
glycogen	low	1	0
meropenem	low	1	0
fosfomycin	low	1	0
decitabine	low	1	0
tamoxifen	low	1	0
bilirubin	low	1	0
lysophosphatidic acid	low	1	0
lead	low	1	0
gallium	low	1	0
indocyanine green	low	1	0
chitosan	low	1	0
interleukin-8	low	2	0
clay	low	1	0
transforming growth factor beta	low	3	0
angiotensin i	low	1	0
rifampin	low	1	0
eye	low	1	0
leptin	low	1	0

Protein Targets (606)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	1	1	2
5-hydroxytryptamine receptor 2A	0	1	1	2
5-hydroxytryptamine receptor 1A	0	3	1	4
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	1	1	2
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	2	1	3
Sodium-dependent serotonin transporter	0	2	0	2
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
Microtubule-associated protein tau	7	0	0	7
thioredoxin glutathione reductase	3	0	0	3
Smad3	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	12	0	0	12
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	0	1	1
glucocerebrosidase	2	0	0	2
DNA polymerase kappa isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	2	0	0	2
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
glp-1 receptor, partial	3	0	0	3
pregnane X receptor	1	0	0	1
GLS protein	4	0	0	4
GLI family zinc finger 3	9	0	0	9
AR protein	9	0	0	9
pregnane X nuclear receptor	4	0	0	4
peroxisome proliferator-activated receptor delta	7	0	0	7
aryl hydrocarbon receptor	5	0	0	5
DNA polymerase iota isoform a (long)	2	0	0	2
nuclear receptor ROR-gamma isoform 1	3	0	0	3
Nuclear receptor ROR-gamma	2	0	0	2
TAR DNA-binding protein 43	4	0	0	4
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Luciferase	2	0	0	2
acid sphingomyelinase	1	0	0	1
acetylcholinesterase	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
RAR-related orphan receptor gamma	8	0	0	8
SMAD family member 2	3	0	0	3
SMAD family member 3	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
progesterone receptor	4	0	0	4
glucocorticoid receptor [Homo sapiens]	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
retinoid X nuclear receptor alpha	5	0	0	5
estrogen-related nuclear receptor alpha	7	0	0	7
farnesoid X nuclear receptor	4	0	0	4
estrogen nuclear receptor alpha	11	0	0	11
peroxisome proliferator activated receptor gamma	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
caspase-3	2	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	3	0	0	3
activating transcription factor 6	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
chromobox protein homolog 1	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
thyroid hormone receptor beta isoform 2	7	0	0	7
heat shock protein beta-1	3	0	0	3
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	10	0	0	10
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
geminin	8	0	0	8
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Cellular tumor antigen p53	6	0	0	6
Cytochrome P450 1A2	0	3	0	3
Tyrosine-protein kinase Fyn	0	2	0	2
Glutamate receptor 2	3	0	0	3
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Aryl hydrocarbon receptor	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, Cruzipain	2	0	0	2
phosphopantetheinyl transferase	5	0	0	5
USP1 protein, partial	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	4	0	0	4
vitamin D3 receptor isoform VDRA	5	0	0	5
caspase-1 isoform alpha precursor	1	0	0	1
lamin isoform A-delta10	2	0	0	2
Caspase-7	1	0	0	1
Inositol monophosphatase 1	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	4	0	6
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	2	0	0	2
Thrombopoietin	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	6	0	0	6
Metallo-beta-lactamase type 2	0	1	2	5
peripheral myelin protein 22 isoform 1	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
ATP-binding cassette sub-family C member 3	0	10	0	10
Multidrug resistance-associated protein 4	0	10	0	10
Bile salt export pump	0	13	0	13
Prothrombin	0	1	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	3	1	4
Angiotensin-converting enzyme	0	4	0	5
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	3
Mu-type opioid receptor	0	1	1	2
Beta-lactamase	0	3	0	5
Canalicular multispecific organic anion transporter 1	0	10	0	10
Beta-lactamase	0	3	0	3
Angiotensin-converting enzyme 2	0	1	1	2
Beta-lactamase class B VIM-2	0	1	2	5
ATP-dependent phosphofructokinase	3	0	0	3
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
muscarinic acetylcholine receptor M1	1	0	0	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	0	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Solute carrier family 22 member 1	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Solute carrier family 22 member 2	0	2	0	3
Chain A, Beta-lactamase	3	0	0	3
ATAD5 protein, partial	2	0	0	2
TDP1 protein	5	0	0	5
EWS/FLI fusion protein	5	0	0	5
67.9K protein	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Spike glycoprotein	2	0	1	3
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	3	0	0	3
Histone H2A.x	4	0	0	4
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Amyloid-beta precursor protein	0	1	0	1
Histamine H2 receptor	3	0	1	4
Metallo-beta-lactamase VIM-13	0	1	0	3
Beta-lactamase VIM-1	0	1	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
arylsulfatase A	4	0	0	4
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	1
Kappa-type opioid receptor	0	1	0	2
B2 metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	1	3
Metallo-b-lactamase	0	0	0	2
Beta-lactamase IMP-1	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
cytochrome P450 3A4 isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	2	0	0	2
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	1	0	1
Bile salt export pump	0	5	0	5
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 3A4	0	4	0	4
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit delta	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	2	0	0	2
Cytochrome P450 2C19	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-2	2	0	0	2
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
GABA theta subunit	2	0	0	2
Endonuclease 8-like 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	2	0	0	2
thioredoxin reductase	3	0	0	3
regulator of G-protein signaling 4	4	0	0	4
NPYLR7B	0	0	1	1
cytochrome P450 2D6	2	0	0	2
Beta-1 adrenergic receptor	0	0	1	2
thyroid stimulating hormone receptor	2	0	0	2
beta-2 adrenergic receptor	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
peripheral myelin protein 22	1	0	0	1
Beta-2 adrenergic receptor	0	2	2	5
Beta-1 adrenergic receptor	0	4	1	5
Beta-2 adrenergic receptor	0	2	1	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Beta-3 adrenergic receptor	0	3	1	4
D(2) dopamine receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	4	0	4
Beta-1 adrenergic receptor	0	2	1	4
Beta-2 adrenergic receptor	0	0	1	1
Alpha-2B adrenergic receptor	0	2	0	2
D(1A) dopamine receptor	0	3	0	3
D(4) dopamine receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Beta-adrenergic receptor kinase 1	0	0	1	1
Alpha-1D adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
D(3) dopamine receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	4	0	4
D(1A) dopamine receptor	2	0	0	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	1	4
Beta-2 adrenergic receptor	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	2	1	3
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	0	2	2
Glutamate receptor ionotropic, NMDA 3B	0	2	1	3
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	2	1	3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Lysophosphatidic acid receptor 6	0	0	1	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 1	0	0	2	2
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 5	0	0	1	1
Lysophosphatidic acid receptor 2	0	0	1	1
Lysophosphatidic acid receptor 3	0	0	1	1
G	3	0	0	3
streptokinase A precursor	0	0	2	2
lethal factor (plasmid)	2	0	0	2
Interferon beta	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Inositol hexakisphosphate kinase 1	3	0	0	3
cytochrome P450 2C9, partial	3	0	0	3
thyroid stimulating hormone receptor	3	0	0	3
5-hydroxytryptamine receptor 3E	0	1	0	1
interleukin 8	2	0	0	2
D(1A) dopamine receptor	2	0	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	1	1	2
Muscarinic acetylcholine receptor M4	0	2	1	3
Muscarinic acetylcholine receptor M5	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Acetylcholine receptor subunit beta	0	2	1	3
Translocator protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Delta-type opioid receptor	0	1	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	3	1	4
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
dopamine D1 receptor	1	0	0	1
thyroid hormone receptor beta isoform a	1	0	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Albumin	0	0	1	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	1	1	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Chain A, Ferritin light chain	2	0	0	2
PINK1	1	0	0	1
Parkin	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
IDH1	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
ATP-dependent translocase ABCB1	0	3	1	4
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Chain A, CES1 protein	0	1	0	1
Fumarate hydratase	1	0	0	1
PPM1D protein	1	0	0	1
DNA polymerase III, partial	1	0	0	1
polyprotein	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Caspase-7	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
interferon gamma precursor	0	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
caspase-3	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
Transmembrane protease serine 2	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Serine/threonine-protein kinase D3	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Estrogen receptor	0	2	1	4
Lysosomal acid glucosylceramidase	0	0	1	1
Integrin beta-3	1	0	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Tyrosine-protein kinase Lck	0	1	0	1
Progesterone receptor	0	1	0	1
Procathepsin L	0	0	1	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Integrin alpha-IIb	1	0	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Adenosine receptor A3	0	2	0	2
Replicase polyprotein 1ab	0	0	1	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Androgen receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Substance-K receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Histamine H2 receptor	0	2	0	2
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Estrogen receptor beta	0	2	1	3
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
mitogen-activated protein kinase 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 2C9	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(7)

Research Excerpts

Overview

Research

Studies (129)

Protein Targets (606)

Anthracosis

Synonyms(7)

Research Excerpts

Overview

Research

Studies (129)

Drugs Studied (51)

Protein Targets (606)