Compounds > methyl vanillate
Page last updated: 2024-12-06

methyl vanillate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Methyl vanillate is a naturally occurring organic compound found in various plants, including vanilla beans. It is an ester formed from vanillin and methanol. Its synthesis can be achieved through esterification of vanillin with methanol. Methyl vanillate has been shown to exhibit antioxidant and anti-inflammatory properties, and it is also known to possess analgesic and antipyretic activities. It is a key component of vanilla flavor and is used in various food and beverage products. Its aroma and taste characteristics make it a popular ingredient in perfumes and cosmetics. Research on methyl vanillate is ongoing to explore its potential applications in medicine and other fields. It is of interest due to its promising biological activities and its potential as a natural alternative to synthetic compounds.'

methyl vanillate: isolated from Hovenia dulcis [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

methyl vanillate : A benzoate ester that is the methyl ester of vanillic acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID19844
CHEMBL ID486214
CHEBI ID46477
SCHEMBL ID275939

Synonyms (61)

Synonym
benzoic acid, 4-hydroxy-3-methoxy-, methyl ester
VXX ,
brn 1369113
ai3-20212
nsc 74385
einecs 223-525-9
methyl 3-methoxy-4-hydroxybenzoate
nsc74385
nsc-74385
methyl 4-hydroxy-3-methoxybenzoate ,
vanillic acid, methyl ester
methyl vanillate
3943-74-6
vanillic acid methyl ester
4-hydroxy-3-methoxybenzoic acid methyl ester
inchi=1/c9h10o4/c1-12-8-5-6(9(11)13-2)3-4-7(8)10/h3-5,10h,1-2h
methyl vanillate, >=98%, fg
methyl vanillate, 99%
methyl vanillic acid
CHEBI:46477 ,
M1738
DB08711
4-hydroxy-3-methoxy methyl benzoate
CHEMBL486214
methylvanillate
BMSE010226
methyl (3-methoxy-4-hydroxy)benzoate
AKOS000120673
A824546
S3630
3-10-00-01410 (beilstein handbook reference)
unii-2hxg8qso3d
2hxg8qso3d ,
FT-0600645
SCHEMBL275939
4-hydroxy-3-methoxy benzoic acid methyl ester
methyl 4-hydroxy-3-methoxy-benzoate
4-hydroxy-3-methoxy-benzoic acid methyl ester
4-hydroxy-5-methoxy -benzoic acid methyl ester
3-methoxy-4-(hydroxy)benzoic acid methyl ester
methyl 4-hydroxy-3-methyoxybenzoate
4-hydroxy-5-methoxy-benzoic acid methyl ester
methyl 4-hydroxy-3-(methyloxy)benzoate
methyl ester of 4-hydroxy-3-methoxybenzoic acid
vanillic acid methyl
W-106434
J-650247
mfcd00008438
HY-75342
DTXSID5074345
CS-D0814
AC-9615
SY003406
Q27097897
AS-13512
AMY528
CCG-266450
methyl4-hydroxy-3-methoxybenzoate
PB42723
EN300-21518
Z104500600
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
antioxidantA substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
benzoate esterEsters of benzoic acid or substituted benzoic acids.
phenolsOrganic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
aromatic etherAny ether in which the oxygen is attached to at least one aryl substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (32)

Assay IDTitleYearJournalArticle
AID354862Antifungal activity against Candida albicans at 60 ug/disk1996Journal of natural products, Aug, Volume: 59, Issue:8
Isoprenyl phenyl ethers from liverworts of the genus Trichocolea: cytotoxic activity, structural corrections, and synthesis.
AID485528Anticancer activity against human U373 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID1309206Anti-allergic activity in RBL2H3 cells assessed as inhibition of anti-DNP-IgE-induced degranulation at 1000 uM incubated for 20 mins followed by DNP-labeled human serum albumin addition measured after 1 hr by beta-hexosaminidase release assay2016Bioorganic & medicinal chemistry letters, 08-01, Volume: 26, Issue:15
Structure-activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells.
AID485527Anticancer activity against human T98G cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID338338Antiplatelet activity against rat platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation at 0.1 mg/ml pretreated 2 mins before collagen challenge
AID485529Chemical stability after 7 days by HPLC2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID1309205Anti-allergic activity in RBL2H3 cells assessed as inhibition of anti-DNP-IgE-induced degranulation incubated for 20 mins followed by DNP-labeled human serum albumin addition measured after 1 hr by beta-hexosaminidase release assay2016Bioorganic & medicinal chemistry letters, 08-01, Volume: 26, Issue:15
Structure-activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells.
AID1102544Inhibition of tyrosinase activity in Oryza sativa Indica (rice) bran using L-tyrosine as substrate at 0.5 umol/ml after 60 min by spectrophotometric analysis2003Journal of agricultural and food chemistry, Nov-19, Volume: 51, Issue:24
Tyrosinase inhibitor from black rice bran.
AID1090826Antifeedant activity against Hylobius abietis (pine weevil ) in compound pre-treated Scots pine twig at 50 mM measured after 24 hr by two-choice laboratory bioassay2007Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
Quantitative structure-activity relationships of pine weevil antifeedants, a multivariate approach.
AID485521Anticancer activity against human OE21 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID376315Antibacterial activity against Escherichia coli ATCC 35218 after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID485519Anticancer activity against mouse B16F10 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID338335Antiplatelet activity against rat platelet rich plasma assessed as inhibition of arachidonic acid-induced platelet aggregation at 0.25 mg/ml pretreated 2 mins before arachidonic acid challenge
AID376321Antibacterial activity against Staphylococcus aureus ATCC 6538 after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID376320Antibacterial activity against Salmonella enteritidis ATCC 13076 after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID485525Anticancer activity against human LoVo cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID485526Anticancer activity against human Hs683 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID376324Antibacterial activity against Bacillus cereus isolate after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID376319Antibacterial activity against Pseudomonas tolaasii after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID376325Antifungal activity against Candida albicans isolate after 72 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID485522Anticancer activity against human PC3 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID354863Antifungal activity against Trichophyton mentagrophytes at 60 ug/disk1996Journal of natural products, Aug, Volume: 59, Issue:8
Isoprenyl phenyl ethers from liverworts of the genus Trichocolea: cytotoxic activity, structural corrections, and synthesis.
AID376322Antibacterial activity against Micrococcus luteus isolate after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID338336Antiplatelet activity against rat platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation at 0.25 mg/ml pretreated 2 mins before collagen challenge
AID485524Anticancer activity against human A549 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID354860Cytotoxicity against african green monkey BSC1 cells at 60 ug/disk1996Journal of natural products, Aug, Volume: 59, Issue:8
Isoprenyl phenyl ethers from liverworts of the genus Trichocolea: cytotoxic activity, structural corrections, and synthesis.
AID338339Antiplatelet activity against rat platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation at 1 mg/ml pretreated 2 mins before ADP challenge
AID376317Antibacterial activity against Agrobacterium tumefaciens A281 after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID376323Antibacterial activity against Sarcina lutea ATCC 9341 after 48 hrs by serial dilution technique2006Journal of natural products, Apr, Volume: 69, Issue:4
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.
AID485520Anticancer activity against human OE33 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID485523Anticancer activity against human MCF7 cells after 24 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
AID338333Antiplatelet activity against rat platelet rich plasma assessed as inhibition of arachidonic acid-induced platelet aggregation at 0.5 mg/ml pretreated 2 mins before arachidonic acid challenge
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.20 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.02 (4.65)
Search Engine Demand Index39.34 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dinitrochlorobenzene
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.. 1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.		2.1310C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
protocatechuic acid
protocatechuic acid: RN given refers to parent cpd; structure. 3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.		2.0110catechols;
dihydroxybenzoic acid		antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite
4-hydroxybenzoic acid
4-hydroxybenzoic acid : A monohydroxybenzoic acid that is benzoic acid carrying a hydroxy substituent at C-4 of the benzene ring.		2.0310monohydroxybenzoic acidalgal metabolite;
plant metabolite
salicylic acid
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).		2.0310monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
gallic acid
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.		2.4110trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.4110alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
vanillin
Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).		2.1310benzaldehydes;
monomethoxybenzene;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite
bay h 4502
bifonazole : A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.. 1-[biphenyl-4-yl(phenyl)methyl]imidazole : A member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1.		2.0310biphenyls;
imidazoles
veratric acid
veratric acid: RN given refers to parent cpd; structure. 3,4-dimethoxybenzoic acid : A member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3.		2.4320benzoic acidsallergen;
plant metabolite
butylparaben
[no description available]		2.1310organic molecular entity
piperonylic acid
piperonylic acid: RN given refers to parent cpd; structure. piperonylic acid : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties.		2.0310aromatic carboxylic acid;
benzodioxoles;
monocarboxylic acid		antifungal agent;
EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor;
plant metabolite;
vulnerary
alpha-resorcylic acid
alpha-resorcylic acid: RN given refers to parent cpd. 3,5-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 5.		2.0310dihydroxybenzoic acid;
resorcinols		metabolite
methyl gallate
methyl gallate: has both immunosuppressive and phytogenic antineoplastic activities; isolated from Acer saccharinum. methyl 3,4,5-trihydroxybenzoate : A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.		2.0310gallate esteranti-inflammatory agent;
antioxidant;
plant metabolite
methylparaben
methylparaben: used as a preservative in cosmetics but potentiates UV-induced damage of skin; RN given refers to parent cpd. methylparaben : A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.		2.0310parabenantifungal agent;
antimicrobial food preservative;
neuroprotective agent;
plant metabolite
vanillic acid
Vanillic Acid: A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).. vanillic acid : A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3.		3.680methoxybenzoic acid;
monohydroxybenzoic acid		plant metabolite
methyl 4-anisate
methyl 4-anisate: volatile biomarker of Mycobacterium tuberculosis; structure in first source. methyl p-anisate : A benzoate ester obtained by the formal condensation of the carboxy group of 4-methoxybenzoic acid with methanol.		2.0310benzoate ester;
monomethoxybenzene
syringic acid
syringic acid: RN given refers to parent cpd; structure in third source. syringic acid : A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.		2.5120benzoic acids;
dimethoxybenzene;
phenols		plant metabolite
isovanillic acid
3-hydroxy-4-methoxybenzoic acid : A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3.		2.4320methoxybenzoic acid;
monohydroxybenzoic acid		antibacterial agent;
plant metabolite
3,4,5-trimethoxybenzamide
[no description available]		2.0310
streptomycin
[no description available]		2.0310antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
3-methoxysalicylic acid
2-hydroxy-3-methoxybenzoic acid: structure in first source		2.0310methoxysalicylic acidmetabolite
methyl syringate
methyl syringate : A benzoate ester obtained by the formal condensation of carboxy group of syringic acid with methanol.		2.0310benzoate ester;
dimethoxybenzene;
phenols		plant metabolite
2-hydroxy-4-methoxy benzoic acid
[no description available]		2.0310methoxybenzoic acid
5-methoxysalicylic acid
5-methoxysalicylic acid: enhances intestinal absorption of insulin in rats; RN given refers to parent cpd. 5-methoxysalicylic acid : A methoxysalicylic acid that is salicylic acid which is carrying a methoxy group at position 5.		2.0310methoxysalicylic acidbacterial metabolite;
human urinary metabolite
methyl 2,4-dihydroxy-3,6-dimethyl benzoate
atraric acid: structure in first source; from the stem barks of Newbouldia laevis		2.03104-hydroxybenzoate ester
methyl 3-(4-hydroxyphenyl)propionate
methyl 3-(4-hydroxyphenyl)propionate: a root-exuded compound responsible for biological nitrification inhibition by sorghum (Sorghum bicolor); structure in first source. methyl 3-(4-hydroxyphenyl)propionate : A methyl ester resulting from the formal condensation of the carboxy group of phloretic acid with methanol. It is a nitrification inhibitor and a plant growth regulator.		2.0310methyl ester;
phenols		nitrification inhibitor;
plant growth regulator
methyl 3,4-dihydroxybenzoate
[no description available]		2.4320catechols;
methyl ester		antioxidant;
neuroprotective agent;
plant metabolite
ferulic acid
ferulate : A monocarboxylic acid anion obtained by the deprotonation of the carboxy group of ferulic acid.		2.1310ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite
ethyl cinnamate
ethyl cinnamate: a pine weevil antifeedant; structure in first source		2.0310alkyl cinnamate;
ethyl ester
phenylalanine methyl ester
phenylalanine methyl ester: RN given refers to (L)-isomer. methyl L-phenylalaninate : An alpha-amino acid ester that is the methyl ester of L-phenylalanine.		2.0310alpha-amino acid ester;
L-phenylalanine derivative
anthecotulide
anthecotulide: from Anthemis cotula; structure in first source		2.0310butan-4-olide
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		02.0510
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.0510
Basophilic Leukemia, Acute
[description not available]		02.1310
Leukemia, Basophilic, Acute
A rare acute myeloid leukemia in which the primary differentiation is to BASOPHILS. It is characterized by an extreme increase of immature basophilic granulated cells in the bone marrow and blood. Mature basophils are usually sparse.		02.1310
Breast Cancer
[description not available]		07.4110
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.4110
Alopecia Cicatrisata
[description not available]		02.1310
Alopecia
Absence of hair from areas where it is normally present.		07.1310
Eczema, Atopic
[description not available]		02.1310
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.1310
Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.		02.1310