Page last updated: 2024-12-10
myomycin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
myomycin: antibiotic whose hydrolysis products are myo-inositol lysine & 3-amino-3-deoxy-D-mannose [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 3084953 |
| SCHEMBL ID | 691424 |
| MeSH ID | M0052538 |
Synonyms (6)
| Synonym |
|---|
| 50926-58-4 |
| myomycin |
| [(1s,2r,3s,4r,5r,6s)-2,6-dicarbamoyloxy-3-[(2r,3s,4s,5s,6r)-4-(diaminomethylideneamino)-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxycyclohexyl] 3-amino-6-(3,6-diaminohexanoylamino)hexanoate |
| SCHEMBL691424 |
| DTXSID60965207 |
| 3,6-diamino-n-[4-amino-6-({3-[(3-carbamimidamido-3-deoxyhexopyranosyl)oxy]-4,5-dihydroxy-2,6-bis[hydroxy(imino)methoxy]cyclohexyl}oxy)-6-oxohexyl]hexanimidic acid |
Research Excerpts
Overview
Myomycin is an unusual pseudodisaccharide antibiotic. It has structural similarities with kasugamycin, streptomycin and streptothricin.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Myomycin is an unusual pseudodisaccharide antibiotic with a beta-lysyl oligopeptide ester side chain that has structural similarities with kasugamycin, streptomycin and streptothricin. " | ( Myomycin: mode of action and mechanism of resistance. Cannon, M; Davies, J; Mauer, MB, 1988) | 3.16 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " therapy with liposomal amphotericin B at a dosage of 3mg/kg/day for 5 days was started and then repeated on the 14th and 21st days, leading to a clear improvement in the clinical picture." | ( Atypical multifocal cutaneous leishmaniasis in an immunocompetent patient treated by liposomal amphotericin B. Amerio, PL; Capizzi, R; De Simone, C; Feliciani, C; Paradisi, A; Proietti, I; Zampetti, A, 2005) | 0.33 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 27.13
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (27.13) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (20.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4 (80.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||