Page last updated: 2024-11-10

myomycin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

myomycin: antibiotic whose hydrolysis products are myo-inositol lysine & 3-amino-3-deoxy-D-mannose [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3084953
SCHEMBL ID691424
MeSH IDM0052538

Synonyms (6)

Synonym
50926-58-4
myomycin
[(1s,2r,3s,4r,5r,6s)-2,6-dicarbamoyloxy-3-[(2r,3s,4s,5s,6r)-4-(diaminomethylideneamino)-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxycyclohexyl] 3-amino-6-(3,6-diaminohexanoylamino)hexanoate
SCHEMBL691424
DTXSID60965207
3,6-diamino-n-[4-amino-6-({3-[(3-carbamimidamido-3-deoxyhexopyranosyl)oxy]-4,5-dihydroxy-2,6-bis[hydroxy(imino)methoxy]cyclohexyl}oxy)-6-oxohexyl]hexanimidic acid

Research Excerpts

Overview

Myomycin is an unusual pseudodisaccharide antibiotic. It has structural similarities with kasugamycin, streptomycin and streptothricin.

ExcerptReferenceRelevance
"Myomycin is an unusual pseudodisaccharide antibiotic with a beta-lysyl oligopeptide ester side chain that has structural similarities with kasugamycin, streptomycin and streptothricin. "( Myomycin: mode of action and mechanism of resistance.
Cannon, M; Davies, J; Mauer, MB, 1988
)
3.16

Dosage Studied

ExcerptRelevanceReference
" therapy with liposomal amphotericin B at a dosage of 3mg/kg/day for 5 days was started and then repeated on the 14th and 21st days, leading to a clear improvement in the clinical picture."( Atypical multifocal cutaneous leishmaniasis in an immunocompetent patient treated by liposomal amphotericin B.
Amerio, PL; Capizzi, R; De Simone, C; Feliciani, C; Paradisi, A; Proietti, I; Zampetti, A, 2005
)
0.33
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.13

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.13 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.25 (4.65)
Search Engine Demand Index29.35 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.13)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (20.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]