Page last updated: 2024-09-27

Infarction, Pulmonary

NECROSIS of lung tissue that is cause by the lack of OXYGEN or blood supply. The most common cause of pulmonary infarction is a blood clot in the lung.

Synonyms(3)

Synonym
Infarction, Pulmonary
Pulmonary Infarction
Pulmonary Infarct

Research Excerpts

Research

Studies (28)

TimeframeStudies, This Condition (%)All Conditions %
pre-199013 (46.43)23.3326
1990's0 (0.00)12.5806
2000's3 (10.71)18.1394
2010's9 (32.14)28.8240
2020's3 (10.71)9.53
DrugIndicatedRelationship StrengthStudiesTrials
coumarin0low30
dalteparin0low10
theophylline0low10
ketorolac0low10
khellin0low10
phenylbutazone0low10
aminopyrine0low10
ethyl chloride0low10
streptomycin0low20
floxacillin0low10
fluorodeoxyglucose f180low40
levofloxacin0low10
moxifloxacin0low10
cocaine0low10
bilirubin0low10
vitamin k semiquinone radical0low20
morphine0low10
iloprost0low10
warfarin0low40
phenprocoumon0low10

Protein Targets (449)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Ferritin light chain2002
Luciferase3003
interleukin 81001
thioredoxin reductase6006
15-lipoxygenase, partial1001
RAR-related orphan receptor gamma3003
GLS protein3003
GLI family zinc finger 35005
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)1001
nuclear receptor subfamily 1, group I, member 33003
cytochrome P450 family 3 subfamily A polypeptide 44004
retinoic acid nuclear receptor alpha variant 14004
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha4004
pregnane X nuclear receptor6006
estrogen nuclear receptor alpha7007
G4004
peroxisome proliferator-activated receptor delta1001
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a1001
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
chromobox protein homolog 15005
thyroid hormone receptor beta isoform a3003
thyroid hormone receptor beta isoform 23003
histone deacetylase 9 isoform 31001
nuclear factor erythroid 2-related factor 2 isoform 13003
geminin6006
lamin isoform A-delta105005
Voltage-dependent calcium channel gamma-2 subunit1001
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Glutamate receptor 21001
Nicotinate phosphoribosyltransferase0202
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
ORF730011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, 2-oxoglutarate Oxygenase3003
Chain A, Cruzipain1001
phosphopantetheinyl transferase3003
USP1 protein, partial6006
Microtubule-associated protein tau2002
aldehyde dehydrogenase 1 family, member A15005
vitamin D3 receptor isoform VDRA4004
DNA polymerase kappa isoform 11001
caspase-1 isoform alpha precursor1001
Caspase-71001
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10203
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10202
5-hydroxytryptamine receptor 2C0202
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0202
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
D0101
5-hydroxytryptamine receptor 1A0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Liver carboxylesterase 10001
Sodium-dependent noradrenaline transporter 0202
Sodium-dependent dopamine transporter0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0202
Sodium-dependent serotonin transporter0304
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium-dependent dopamine transporter 0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Potassium voltage-gated channel subfamily H member 20506
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0101
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0101
Sigma non-opioid intracellular receptor 10303
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0202
Chain A, Beta-lactamase3003
pregnane X receptor2002
GALC protein2002
AR protein3003
glucocorticoid receptor [Homo sapiens]5005
farnesoid X nuclear receptor1001
nuclear receptor subfamily 1, group I, member 21001
DNA polymerase iota isoform a (long)4004
peripheral myelin protein 224004
glycogen synthase kinase-3 alpha0001
muscleblind-like protein 1 isoform 12002
Exportin-10101
Carbonic anhydrase 120102
Bile salt export pump011011
Carbonic anhydrase 10102
Carbonic anhydrase 20102
Glyceraldehyde-3-phosphate dehydrogenase0101
NAD-dependent histone deacetylase SIR20103
Carbonic anhydrase 30101
Cytochrome P450 2A60001
Aldo-keto reductase family 1 member B10101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
Amine oxidase [flavin-containing] B0101
Cytochrome P450 2A50001
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0101
Acetylcholinesterase0101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0101
Carbonic anhydrase 40101
Carbonic anhydrase 60101
Substance-P receptor0001
Carbonic anhydrase 5A, mitochondrial0101
UDP-glucuronosyltransferase 2B10 0101
Carbonic anhydrase 70101
Quinone oxidoreductase0001
Beta-secretase 10101
Sorbitol dehydrogenase0101
Induced myeloid leukemia cell differentiation protein Mcl-10202
Carbonic anhydrase 90102
Zn finger protein 0101
Dihydroorotate dehydrogenase 0101
Carbonic anhydrase 130101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
Bile salt export pump0303
Solute carrier family 15 member 10101
Chain A, BCL-2-RELATED PROTEIN A10011
acetylcholinesterase1001
apical membrane antigen 1, AMA11001
cytochrome P450 2D62002
unnamed protein product0101
transcriptional regulator ERG isoform 32002
heat shock protein HSP 90-alpha isoform 20001
cytochrome P450 3A4 isoform 13003
bcl-2-like protein 11 isoform 10011
Gamma-aminobutyric acid receptor subunit pi3003
Histone deacetylase 30101
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
Rap guanine nucleotide exchange factor 32002
Chymotrypsinogen A0101
Beta-lactamase0101
Cellular tumor antigen p534004
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10203
Cytochrome P450 3A40415
Lanosterol 14-alpha demethylase0112
Aromatase0101
Cytochrome P450 2C9 0404
Gamma-aminobutyric acid receptor subunit beta-13003
Cytochrome P450 11B1, mitochondrial0101
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Cytochrome P450 11B2, mitochondrial0101
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
ATP-dependent translocase ABCB10202
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Heme oxygenase 20101
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Malate dehydrogenase, cytoplasmic0101
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
TAR DNA-binding protein 433003
Histone deacetylase 10101
Lanosterol 14-alpha demethylase0112
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
Histone deacetylase 70101
GABA theta subunit3003
Histone deacetylase 20101
Canalicular multispecific organic anion transporter 10303
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
14-alpha sterol demethylase 0011
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit epsilon3003
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
Prostaglandin E2 receptor EP1 subtype0011
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP2 subtype0011
Prostacyclin receptor0213
Prostacyclin receptor0112
Spike glycoprotein4004
Solute carrier organic anion transporter family member 2A10001
Prostaglandin D2 receptor0011
EWS/FLI fusion protein4004
euchromatic histone-lysine N-methyltransferase 27007
NPC intracellular cholesterol transporter 1 precursor1001
ras-related protein Rab-9A1001
Fatty acid-binding protein, liver0101
Albumin0112
Fatty acid-binding protein, intestinal0112
Prostaglandin G/H synthase 10101
Caspase-10101
Prostaglandin G/H synthase 20202
Caspase-30101
Caspase-40101
Caspase-50101
Caspase-90101
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10101
Serine/threonine-protein kinase PAK 10101
Ataxin-21001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
glp-1 receptor, partial1001
TDP1 protein4004
aryl hydrocarbon receptor1001
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C19 precursor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
importin subunit beta-1 isoform 11001
mitogen-activated protein kinase 12002
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
survival motor neuron protein isoform d2002
histone acetyltransferase KAT2A isoform 14004
Cytochrome P450 1A10202
Cytochrome P450 1A20202
Cytochrome P450 2D60202
Cytochrome P450 2C190101
Cytochrome P450 1B10101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
DNA polymerase beta1001
streptokinase A precursor0011
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
Fatty-acid amide hydrolase 10101
DNA gyrase subunit A0203
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Multidrug and toxin extrusion protein 10101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
Opioid receptor, delta 1b 0101
Solute carrier family 22 member 1 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0011
Muscarinic acetylcholine receptor M20101
Translocator protein0011
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Delta-type opioid receptor0102
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0216
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0202
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
DNA gyrase subunit B0101
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
Replicase polyprotein 1ab0202
Replicase polyprotein 1ab0202
DNA topoisomerase 2-alpha0001
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0102
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Protease 0303
Estrogen receptor 10101
regulator of G-protein signaling 41001
nonstructural protein 11001
Parkin1001
peroxisome proliferator activated receptor gamma2002
Bloom syndrome protein isoform 11001
cytochrome P450 2C9 precursor1001
D(1A) dopamine receptor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
fMet-Leu-Phe receptor0101
M-phase phosphoprotein 81001
neuropeptide S receptor isoform A1001
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 2 0101
Histamine H2 receptor1001
Prostaglandin G/H synthase 1 0101
Cyclooxygenase-2 0101
Solute carrier family 22 member 80101
ATP-dependent phosphofructokinase2002
muscarinic acetylcholine receptor M11001
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Protein-arginine deiminase type-40202
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
bromodomain adjacent to zinc finger domain 2B1001
arylsulfatase A1001
IDH11001
Phosphodiesterase 0202
lethal factor (plasmid)1001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Potassium channel subfamily K member 20011
Renin0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
5-hydroxytryptamine receptor 1A0101
Intestinal-type alkaline phosphatase0101
Adenosine receptor A30101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
D(3) dopamine receptor0101
Adenosine receptor A10203
Adenosine receptor A10202
Adenosine receptor A30101
Adenosine receptor A2a0225
Adenosine receptor A2b0102
Adenosine receptor A2b0102
Adenosine receptor A10215
Adenosine receptor A2a0103
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
Nuclear receptor ROR-gamma1001
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Guanine nucleotide-binding protein G1001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
Adenylate cyclase type 10001
Chitotriosidase-10101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Sigma non-opioid intracellular receptor 10101
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Endochitinase B10101
Phospholipase A-2-activating protein0101
thioredoxin glutathione reductase1001
PPM1D protein1001
progesterone receptor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]