Adrenal Hyperplasia, Congenital

A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.

Synonym
Adrenal Hyperplasia, Congenital

Excerpt	Reference
"Congenital adrenal hyperplasia is a group of autosomal recessive disorders leading to multiple complex hormonal imbalances caused by various enzyme deficiencies in the adrenal steroidogenic pathway."	( Auer, MK; Lajic, S; Nordenström, A; Reisch, N, 2023)
"Congenital adrenal hyperplasia is a group of autosomal recessive disorders leading to multiple complex hormonal imbalances caused by various enzyme deficiencies in the adrenal steroidogenic pathway."	( Auer, MK; Lajic, S; Nordenström, A; Reisch, N, 2023)
"Congenital Adrenal Hyperplasia is a group of autosomal recessive diseases due to deficiencies of enzymes involved in steroidogenesis."	( Adhikari, A; Adhikari, N; Chapagain, N; Mandal, D; Paudel, S, 2023)
"Congenital Adrenal Hyperplasia is a group of autosomal recessive disorders due to deficiencies of enzymes involved in steroidogenesis."	( Adhikari, U; Khanal, D; Mandal, D; Phuyal, R, 2020)
"Congenital adrenal hyperplasia is an autossomic recessive condition."	( Ferraz Liz, C; Rocha, A, 2021)
"Congenital adrenal hyperplasia is generally associated with oligo-amenorrhea, and its presentation with polymenorrhagia is rare."	( Hayat, M; Rizwan, A, 2015)
"Congenital adrenal hyperplasia is a genetic endocrinologic disorder."	( Dey, AC; Dey, SK; Khan, KA; Mannan, MA; Nahar, N; Shahidullah, M, 2016)
"Congenital adrenal hyperplasia is a group of disorders caused by defects in the adrenal steroidogenic pathways."	( Dauber, A; Kellogg, M; Majzoub, JA, 2010)
"Congenital adrenal hyperplasia is an autosomal recessive disorder; 21-hydroxylase deficiency (21OHD) is the most common form of the disease."	( Lekarev, O; New, MI, 2011)
"Congenital adrenal hyperplasia is a group of autosomal recessive inherited disorders of steroidogenesis."	( Grischuk, Y; Grötzinger, J; Holterhus, PM; Krone, N; Müller, M; Riepe, FG; Sippell, WG; Volk, RE, 2006)
"Congenital adrenal hyperplasia is a general term applied to a group of several inherited enzymatic defects of cortisol biosynthesis."	( Herman, ZS; Krysiak, R; Okopień, B, 2006)
"Congenital adrenal hyperplasia is a group of inherited disorders caused by an enzyme deficiency in steroid biosynthesis."	( New, MI; Nimkarn, S, 2007)
"Congenital adrenal hyperplasia is a group of autosomal recessive disorders resulting from the deficiency of one of the five enzymes required for the synthesis of cortisol in the adrenal cortex."	( Biason-Lauber, A; Torresani, T, 2007)
"Congenital adrenal hyperplasia is one of a few inherited disorders that can be managed by administering medication to the fetus via oral maternal administration."	( New, MI; Speiser, PW, 1994)
"Congenital adrenal hyperplasia is the most frequent cause of adrenal insufficiency and ambiguous genitalia in newborn children."	( Bettendorf, M; de Launoit, Y; Gordon, RD; Heinrich, U; Laflamme, N; Luu-The, V; Rhéaume, E; Sanchez, R; Simard, J; van Seters, AP, 1993)

Excerpt	Reference
"The standard treatment for congenital adrenal hyperplasia (CAH) in children is still hydrocortisone."	( Falhammar, H; Lajic, S; Nordenström, A, 2023)
"Although the basic treatment of congenital adrenal hyperplasia (CAH) is well established, there are active clinical research projects to more closely mimic the normal diurnal rhythm of cortisol secretion and to reduce total glucocorticoid doses to minimize adverse metabolic effects."	( White, PC, 2022)
"If not diagnosed and treated adequately, Congenital Adrenal Hyperplasia can lead to an acute adrenal crisis with hemodynamic collapse."	( Adhikari, A; Adhikari, N; Chapagain, N; Mandal, D; Paudel, S, 2023)
"Prenatal dexamethasone (DEX) treatment in congenital adrenal hyperplasia (CAH) is effective in reducing virilization in affected girls, but potential long-term adverse effects are largely unknown."	( Gezelius, A; Hirvikoski, T; Karlsson, L; Lajic, S; Messina, V; Nordenström, A; Sandberg, MT; Wallensteen, L, 2018)
"Prenatal treatment of congenital adrenal hyperplasia with dexamethasone (DEX) has been in use since the mid-1980s and has proven effective at reducing virilization of external genitalia in affected girls."	( Karlsson, L; Lajic, S; Nordenström, A, 2018)
"Prenatal treatment of congenital adrenal hyperplasia by administering dexamethasone to a woman presumed to be carrying an at-risk fetus remains a controversial experimental treatment."	( Miller, WL, 2015)
"Prenatal treatment of congenital adrenal hyperplasia (CAH) has long involved prenatal treatment with dexamethasone, administered to the pregnant woman to prevent genital masculinization of an affected female fetus."	( Rechitsky, S; Simpson, JL, 2017)
"The aim of treatment in congenital adrenal hyperplasia is to suppress excess adrenal androgens while achieving physiological glucocorticoid replacement."	( Andrew, R; Elfick, AP; Homer, NZ; Livingstone, DE; Mackenzie, SD; Mole, DJ; Morgan, RA; Mouras, R; Nixon, M; Reynolds, RM; Stimson, RH; Taylor, AI; Walker, BR, 2016)
"Existing glucocorticoid treatment for congenital adrenal hyperplasia (CAH) is suboptimal and nonphysiological."	( Arlt, W; Calis, KA; Kim, MS; Merke, DP; Nieman, LK; Ravindran, S; Ross, RJ; Sinaii, N; Vanryzin, C; Verma, S, 2010)
"Prenatal treatment of congenital adrenal hyperplasia (CAH) with dexamethasone (DEX) has been in use since the mid- 1980s."	( Hirvikoski, T; Lajic, S; Nordenström, A, 2011)
"Doses of glucocorticoids used when treating congenital adrenal hyperplasia (CAH) are larger than physiological secretion of hydrocortisone in healthy people."	( Giżewska, M; Horodnicka-Józwa, A; Kotkowiak, L; Krupa, B; Krzywińska-Zdeb, E; Petriczko, E; Romanowska, H; Safranow, K; Walczak, M, 2012)
"Prenatal treatment of congenital adrenal hyperplasia by administering dexamethasone to a woman presumed to be carrying an at-risk fetus has been described as safe and effective in several reports."	( Miller, WL; Witchel, SF, 2013)
"Prenatal diagnosis and treatment of congenital adrenal hyperplasia has been implemented for more than 20 years."	( New, MI; Nimkarn, S, 2007)
"The mean age at menarche in 6 girls on treatment for congenital adrenal hyperplasia from infancy was 13."	( Hughes, IA; Read, GF, 1982)
"In a female with untreated congenital adrenal hyperplasia and an adult bone age, signs of puberty appeared very rapidly once appropriate treatment had begun."	( Jocham, A; Kuhnle, U; Schwarz, HP, 1995)
"Since 1986, prenatal diagnosis and treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21-OHD) have been carried out in 239 pregnancies."	( Cheng, KC; Mercado, AB; New, MI; Wei, JQ; Wilson, RC, 1995)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1246 (43.04)	23.3326
1990's	447 (15.44)	12.5806
2000's	457 (15.79)	18.1394
2010's	533 (18.41)	28.8240
2020's	212 (7.32)	9.53

Drug	Relationship Strength	Studies	Trials
5-hydroxytryptophan	low	1	0
acetaldehyde	low	2	0
adenine	low	1	0
choline	low	1	0
citric acid, anhydrous	low	1	0
chlorine	low	1	0
salicylic acid	low	1	0
methylmalonic acid	low	3	0
creatine	low	1	0
cytosine	low	1	0
dimethyl sulfoxide	low	1	0
glycine	low	4	0
hydrogen carbonate	medium	1	1
histamine	low	1	0
iodine	low	2	0
dihydroxyphenylalanine	low	1	0
melatonin	low	4	0
nitrous oxide	low	1	0
purine	low	1	0
taurine	low	1	0
thymine	low	1	0
uric acid	low	3	0
urea	medium	6	1
pk 11195	low	1	0
meglutol	low	1	0
acetaminophen	low	1	0
diatrizoic acid	low	1	0
aminoglutethimide	medium	6	1
amobarbital	low	1	0
anastrozole	low	2	0
antipyrine	low	2	0
aspirin	low	2	0
carbamazepine	low	1	0
chlorpromazine	low	1	0
cimetidine	low	4	0
cisapride	medium	1	1
cyproheptadine	low	1	0
debrisoquin	low	1	0
eflornithine	low	3	0
pentetic acid	low	1	0
erythrosine	low	1	0
ether	low	1	0
ethosuximide	low	1	0
flumazenil	low	2	0
furosemide	low	2	0
glutethimide	low	2	0
guanidine	low	1	0
halothane	low	2	0
ethidium	low	1	0
indomethacin	low	1	0
isoniazid	low	1	0
2-propanol	low	1	0
isoproterenol	low	1	0
ketoconazole	low	4	0
metformin	low	8	0
metoclopramide	medium	1	1
metyrapone	medium	42	1
mitotane	low	4	0
pioglitazone	medium	2	2
potassium chloride	low	2	0
primidone	low	1	0
propofol	low	1	0
propranolol	low	2	0
risperidone	low	1	0
sevoflurane	low	1	0
thioridazine	low	1	0
tolbutamide	low	2	0
trifluoperazine	low	1	0
hydrocortisone acetate	low	6	0
corticosterone	medium	75	1
estriol	low	11	0
hydroxyproline	low	1	0
thyroxine	low	6	0
spironolactone	low	19	0
prednisolone acetate	low	1	0
aldosterone	medium	205	5
lynestrenol	low	1	0
tetrahydrocortisol	low	5	0
tetrahydrocortisone	low	10	0
estrone	medium	15	1
paramethasone	low	2	0
fluprednisolone	low	1	0
androsterone	medium	40	2
etiocholanolone	medium	18	1
dehydroepiandrosterone	medium	145	4
triiodothyronine	low	1	0
carbon tetrachloride	low	1	0
alanine	low	1	0
serine	low	7	0
desoxycorticosterone acetate	low	1	0
chloramphenicol	low	1	0
aspartic acid	low	1	0
glutamine	low	1	0
cyanides	low	3	0
ethinyl estradiol	low	12	0
testosterone propionate	low	1	0
methyltestosterone	low	4	0
adenosine diphosphate	low	1	0
kanamycin a	low	1	0
levodopa	low	1	0
tyrosine	low	4	0
leucine	low	10	0
androstenedione	medium	197	14
methionine	low	1	0
phenylalanine	low	4	0
desoxycorticosterone	medium	109	2
norethindrone	low	2	0
norethynodrel	low	3	0
17-alpha-hydroxyprogesterone	medium	661	34
asparagine	low	3	0
histidine	low	7	0
medroxyprogesterone acetate	low	5	0
valine	low	2	0
threonine	low	1	0
mestranol	low	5	0
dichlorodiphenyldichloroethane	low	3	0
methandrostenolone	low	3	0
tryptophan	low	3	0
isoleucine	low	3	0
arginine	low	18	0
fluoxymesterone	low	1	0
triparanol	low	1	0
pantothenic acid	low	1	0
methylprednisolone	low	12	0
n-vinyl-2-pyrrolidinone	low	1	0
phenothiazine	low	1	0
benzoyl peroxide	low	1	0
pyrrolidonecarboxylic acid	low	1	0
pyridostigmine bromide	low	1	0
pregnenolone	medium	38	1
20-alpha-dihydroprogesterone	low	1	0
cyclopentane	low	1	0
oxazoles	low	4	0
pyrimidine	low	1	0
hydrazine	low	1	0
chlormadinone acetate	low	4	0
dexamethasone 21-phosphate	low	1	0
testosterone enanthate	low	1	0
nandrolone decanoate	low	1	0
betamethasone	low	6	0
cyproterone acetate	medium	19	2
nandrolone	low	2	0
medroxyprogesterone	low	8	0
androstenediol	medium	4	1
dihydrotestosterone	low	21	0
18-hydroxycorticosterone	low	14	0
docusate	low	1	0
algestone	low	1	0
ethylmalonic acid	low	1	0
3-methylglutaric acid	low	1	0
dehydroepiandrosterone sulfate	medium	84	3
testolactone	medium	5	2
glycyrrhizic acid	low	1	0
s,n,n'-tripropylthiocarbamate	medium	2	1
dexamethasone isonicotinate	low	1	0
mannose	low	1	0
megestrol	low	1	0
streptomycin	low	1	0
metanephrine	low	4	0
metomidate	low	1	0
iodinated glycerol	low	4	0
dysprosium	low	1	0
manganese	low	1	0
samarium	low	1	0
technetium	low	1	0
terbium	low	1	0
europium	low	1	0
gold	low	2	0
yttrium	low	1	0
deuterium	low	3	0
ammonium chloride	medium	2	1
clemastine	low	1	0
danazol	low	1	0
bromocriptine	low	2	0
phenyl acetate	low	3	0
triamcinolone	low	9	0
fludrocortisone	medium	120	3
pregnanolone	low	4	0
4-methoxyamphetamine	low	2	0
8-bromo cyclic adenosine monophosphate	medium	1	1
androstane-3,17-diol	low	10	0
glutamic acid	low	2	0
methyldopa	low	1	0
vecuronium bromide	low	1	0
captopril	low	1	0
buserelin	low	2	0
simvastatin	low	2	0
mifepristone	low	1	0
finasteride	low	3	0
aromasil	low	1	0
remifentanil	low	1	0
atorvastatin	low	1	0
3-iodobenzylguanidine	low	1	0
efavirenz	low	1	0
18-hydroxydeoxycorticosterone	low	10	0
6-sulfatoxymelatonin	low	3	0
iopamidol	medium	1	1
tetrahydro-11-deoxycortisol	low	4	0
triazoles	low	2	0
fluorodeoxyglucose f18	low	1	0
adosterol	low	3	0
fibrinogen	low	1	0
17-alpha-hydroxypregnenolone	medium	39	2
homocysteine	low	3	0
11-hydroxyprogesterone	low	5	0
5-alpha-dihydroprogesterone	low	1	0
21-deoxycortisol	medium	42	3
tetrahydrodeoxycorticosterone	low	2	0
pregnanetriol	medium	161	4
deoxypyridinoline	low	1	0
pregnenolone sulfate	low	2	0
cyproterone acetate, ethinyl estradiol drug combination	low	2	0
11-hydroxyandrostenedione	low	12	0
3-monoiodothyronine	low	1	0
valerates	low	1	0
androsterone glucuronide	medium	2	1
11-hydroxytestosterone	low	2	0
selenonorcholesterol	low	2	0
tetrahydroaldosterone	low	1	0
n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea	medium	2	1
abiraterone	low	2	0
proline	low	10	0
17-hydroxypregnenolone sulfate	low	2	0
16-hydroxyprogesterone	low	2	0
17-hydroxypregnanolone	low	3	0
20-hydroxycortisol	low	1	0
21-deoxytetrahydroaldosterone	low	1	0
technetium tc 99m pentetate	low	1	0
21-deoxyaldosterone	low	2	0
biotin	low	2	0
angiotensin ii	low	16	0
ropivacaine	low	1	0
deflazacort	low	1	0
cholic acid	low	2	0
cortisone	medium	162	2
adrenosterone	low	1	0
allylestrenol	low	1	0
19-hydroxy-4-androstene-3,17-dione	low	1	0
pregnanetriolone	low	12	0
withaferin a	low	1	0
7-dehydrocholesterol	low	1	0
inositol 3-phosphate	low	1	0
cortodoxone	medium	98	5
eplerenone	low	2	0
tacrolimus	low	1	0
diethylstilbestrol	low	6	0
carbenoxolone sodium	low	4	0
isomethyleugenol	low	1	0
stilbenes	low	1	0
flavin-adenine dinucleotide	low	1	0
arginine vasopressin	low	2	0
trilostane	low	1	0
prednisolone hemisuccinate	low	1	0
leuprolide	low	12	0
etomidate	low	1	0
methimazole	low	1	0
enclomiphene	low	19	0
3-methylglutaconic acid	low	1	0
D-fructopyranose	low	1	0
tamoxifen	low	2	0
nadp	low	4	0
ranitidine	low	1	0
androstane-3,17-diol glucuronide	low	7	0
cystine	low	1	0
17-ketosteroids	medium	271	6
osteoprotegerin	low	3	0
19-nordeoxycorticosterone	low	3	0
bilirubin	low	2	0
dinoprostone	low	2	0
calcitriol	medium	2	1
cyhalothrin	low	1	0
11-ketotestosterone	low	7	0
isotretinoin	low	1	0
cyproterone	medium	24	2
ethisterone	low	1	0
naloxone	medium	2	1
topiramate	low	1	0
goserelin	low	1	0
thallium	low	1	0
naltrexone	low	1	0
gallium	low	1	0
cysteine	low	4	0
thyronines	low	2	0
silicon	medium	2	1
selenium	low	2	0
pregnanediol	low	45	0
dutasteride	low	1	0
orteronel	low	1	0
alphadolone	low	1	0
sincalide	low	1	0
cystathionine	low	1	0
11 beta-hydroxyandrosterone	low	4	0
oxadiazoles	medium	2	2
3beta-hydroxy-17-(1h-benzimidazole-1-yl)androsta-5,16-diene	low	1	0
11-ketodihydrotestosterone	low	1	0
pituitrin	medium	6	1
enerbol	low	1	0
acid phosphatase	low	3	0
nad	low	4	0
9-fluorocortisone	low	6	0
cosyntropin	low	42	0
atrial natriuretic factor	low	3	0
adrenocorticotropin zinc	low	2	0
glucagon	low	1	0
beta-endorphin	low	2	0
angiotensinogen	low	2	0
oligonucleotides	low	9	0
c-peptide	low	1	0
endothelin-1	low	1	0
sodium salicylate	low	2	0
ubiquinone	low	1	0
calpain	low	1	0
19-iodocholesterol	low	1	0
menotropins	low	3	0
bucladesine	low	1	0
sodium ethylxanthate	low	13	0
cortisol succinate, sodium salt	low	1	0
trelstar	medium	10	3
nafarelin	low	2	0
piperidines	low	1	0
18-hydroxycortisol	low	1	0
dihydrotestosterone glucuronide	low	1	0
heme	low	9	0
transforming growth factor beta	low	1	0
sybr green i	low	1	0
pyrethrins	low	1	0
kiss1 protein, human	low	1	0
rome	low	1	0
vt-464	low	1	0
angiotensin i	low	1	0
vitamin b 12	low	1	0
flavin mononucleotide	low	2	0
exudates	low	4	0
cyclic gmp	low	1	0
guanine	low	2	0
neopterin	low	1	0
leptin	low	12	0

Protein Targets (1,571)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Cruzipain	14	0	0	14
IDH1	22	0	0	22
DNA polymerase iota isoform a (long)	24	0	0	24
geminin	72	0	0	72
Sex hormone-binding globulin	0	1	23	24
acetylcholinesterase	29	0	0	29
pregnane X receptor	21	0	0	21
SMAD family member 2	29	0	0	29
SMAD family member 3	29	0	0	29
TDP1 protein	82	0	0	82
GLI family zinc finger 3	78	0	0	78
Microtubule-associated protein tau	29	0	0	29
AR protein	115	0	0	115
progesterone receptor	69	0	0	69
glucocorticoid receptor [Homo sapiens]	93	0	0	93
retinoic acid nuclear receptor alpha variant 1	75	0	0	75
retinoid X nuclear receptor alpha	65	0	0	65
estrogen-related nuclear receptor alpha	89	0	0	89
farnesoid X nuclear receptor	48	0	0	48
pregnane X nuclear receptor	73	0	0	73
estrogen nuclear receptor alpha	126	0	0	126
G	41	0	0	41
vitamin D (1,25- dihydroxyvitamin D3) receptor	56	0	0	56
arylsulfatase A	19	0	0	19
euchromatic histone-lysine N-methyltransferase 2	63	0	0	63
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	74	0	0	74
activating transcription factor 6	32	0	0	32
nuclear receptor subfamily 1, group I, member 2	20	0	0	20
chromobox protein homolog 1	43	0	0	43
nuclear factor erythroid 2-related factor 2 isoform 1	75	0	0	75
survival motor neuron protein isoform d	24	0	0	24
histone acetyltransferase KAT2A isoform 1	19	0	0	19
lamin isoform A-delta10	55	0	0	55
Voltage-dependent calcium channel gamma-2 subunit	40	0	0	40
Interferon beta	56	0	0	56
HLA class I histocompatibility antigen, B alpha chain	41	0	0	41
Glucocorticoid receptor	1	45	7	61
Glycine receptor subunit alpha-1	0	42	0	42
Corticosteroid-binding globulin	0	19	0	20
Adenosine receptor A3	0	19	1	20
Replicase polyprotein 1ab	0	5	3	8
Androgen receptor	0	52	1	54
Alpha-1B adrenergic receptor	0	28	1	29
Glutamate receptor 2	41	2	1	44
Glycine receptor subunit beta	0	42	0	42
Glycine receptor subunit alpha-2	0	42	0	42
Glycine receptor subunit alpha-3	0	42	0	42
Mitogen-activated protein kinase 3	0	1	0	1
Alpha-1A adrenergic receptor	0	29	1	30
Sodium-dependent dopamine transporter	0	24	0	24
TAR DNA-binding protein 43	21	0	0	21
Inositol hexakisphosphate kinase 1	41	0	0	41
cytochrome P450 2C9, partial	41	0	0	41
ATP-dependent phosphofructokinase	22	0	0	22
Olfactory receptor 51E2	0	1	4	5
hypoxia-inducible factor 1 alpha subunit	28	0	0	28
RAR-related orphan receptor gamma	78	0	0	78
aldehyde dehydrogenase 1 family, member A1	43	0	0	43
peroxisome proliferator-activated receptor delta	49	0	0	49
v-jun sarcoma virus 17 oncogene homolog (avian)	41	0	0	41
Histone H2A.x	31	0	0	31
thyroid hormone receptor beta isoform a	28	0	0	28
heat shock protein beta-1	32	0	0	32
Chain A, Beta-lactamase	21	0	0	21
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
Skn7p	0	0	0	1
ATAD5 protein, partial	22	0	0	22
nonstructural protein 1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	27	0	0	27
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	12	0	0	12
muscleblind-like protein 1 isoform 1	11	0	0	11
Rap guanine nucleotide exchange factor 3	9	0	0	9
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	38	0	0	38
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	20	0	0	20
dopamine D1 receptor	6	0	0	6
thioredoxin reductase	32	0	0	32
GLS protein	22	0	0	22
Thrombopoietin	6	0	0	6
cytochrome P450 2D6 isoform 1	13	0	0	13
cytochrome P450 2C19 precursor	16	0	0	16
ras-related protein Rab-9A	7	0	0	7
lethal factor (plasmid)	22	0	0	22
POU domain, class 2, transcription factor 1	0	0	0	1
Spike glycoprotein	33	1	3	37
glp-1 receptor, partial	16	0	0	16
Steroid 17-alpha-hydroxylase/17,20 lyase	0	9	1	10
Steroid 21-hydroxylase	0	4	0	4
Androgen receptor	1	22	11	38
5-hydroxytryptamine receptor 2C	0	8	2	10
5-hydroxytryptamine receptor 2A	0	10	3	13
5-hydroxytryptamine receptor 1A	0	20	3	25
5-hydroxytryptamine receptor 1B	0	19	1	20
5-hydroxytryptamine receptor 1D	0	4	1	5
5-hydroxytryptamine receptor 1F	0	4	1	5
5-hydroxytryptamine receptor 2B	0	8	2	10
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	32	1	33
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	4	1	5
5-hydroxytryptamine receptor 4	0	1	2	5
5-hydroxytryptamine receptor 3B	0	4	1	5
G-protein coupled bile acid receptor 1	0	1	7	8
Vitamin D3 receptor	0	3	4	11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
ATP-binding cassette sub-family C member 3	0	53	0	53
Multidrug resistance-associated protein 4	0	54	0	57
Bile salt export pump	0	79	0	79
Cytochrome P450 3A4	0	22	2	27
Aromatase	0	18	0	25
Steroid 17-alpha-hydroxylase/17,20 lyase	0	4	0	4
Cytochrome P450 11B1, mitochondrial	0	5	0	5
Cytochrome P450 11B2, mitochondrial	0	5	0	5
Canalicular multispecific organic anion transporter 1	0	51	0	51
thyroid hormone receptor beta isoform 2	73	0	0	73
caspase 7, apoptosis-related cysteine protease	16	0	0	16
thyroid stimulating hormone receptor	30	0	0	30
estrogen receptor 2 (ER beta)	45	0	0	45
nuclear receptor subfamily 1, group I, member 3	53	0	0	53
peroxisome proliferator activated receptor gamma	52	0	0	52
caspase-3	16	0	0	16
thyroid stimulating hormone receptor	33	0	0	33
thyrotropin-releasing hormone receptor	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	34	0	0	34
Caspase-7	12	0	0	12
caspase-3	12	0	0	12
Cellular tumor antigen p53	56	0	0	56
ATPase family AAA domain-containing protein 5	24	0	0	24
Ataxin-2	29	0	0	29
Smad3	16	0	0	16
EWS/FLI fusion protein	28	0	0	28
aryl hydrocarbon receptor	29	0	0	29
peripheral myelin protein 22	33	0	0	33
cytochrome P450 3A4 isoform 1	31	0	0	31
Gamma-aminobutyric acid receptor subunit pi	31	10	4	45
Solute carrier family 22 member 6	0	8	0	8
Carbonic anhydrase 12	0	4	0	12
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	16	0	16
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	15	0	29
Carbonic anhydrase 2	0	17	1	33
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	1	1	3
Cytochrome P450 1A2	0	8	1	11
Prostaglandin G/H synthase 1	0	6	0	7
Carbonic anhydrase 3	0	4	0	10
Cytochrome P450 2D6	0	18	1	20
Cytochrome P450 2C9	0	18	0	19
Polyunsaturated fatty acid lipoxygenase ALOX15	0	13	0	13
Gamma-aminobutyric acid receptor subunit beta-1	31	10	4	45
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	31	10	4	45
Gamma-aminobutyric acid receptor subunit gamma-2	31	11	4	46
UDP-glucuronosyltransferase 1-6	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	31	11	4	46
Gamma-aminobutyric acid receptor subunit alpha-3	31	10	4	45
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	4	0	7
Carbonic anhydrase 4	0	8	0	16
Prostaglandin G/H synthase 1	0	12	0	12
Carbonic anhydrase 6	0	4	0	12
Gamma-aminobutyric acid receptor subunit gamma-1	31	10	4	45
Gamma-aminobutyric acid receptor subunit alpha-2	31	10	4	45
Gamma-aminobutyric acid receptor subunit alpha-4	31	10	4	45
Gamma-aminobutyric acid receptor subunit gamma-3	31	10	4	45
Gamma-aminobutyric acid receptor subunit alpha-6	31	10	4	45
Carbonic anhydrase 5A, mitochondrial	0	5	1	14
Prostaglandin G/H synthase 2	0	11	1	13
Carbonic anhydrase 7	0	4	0	12
Nuclear receptor ROR-gamma	20	0	0	20
Cytochrome P450 2J2	0	12	0	12
Gamma-aminobutyric acid receptor subunit alpha-1	31	11	4	46
Gamma-aminobutyric acid receptor subunit beta-3	31	11	4	46
Gamma-aminobutyric acid receptor subunit beta-2	31	10	4	45
Carbonic anhydrase 9	0	5	0	13
GABA theta subunit	31	10	4	45
Carbonic anhydrase 15	0	6	0	12
Carbonic anhydrase 13	0	4	0	11
Gamma-aminobutyric acid receptor subunit epsilon	31	10	4	45
Carbonic anhydrase 14	0	4	0	12
Carbonic anhydrase 5B, mitochondrial	0	4	0	12
toxin B	0	0	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	54	0	0	54
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	25	0	0	25
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	19	5	27
Delta-type opioid receptor	0	13	6	22
Kappa-type opioid receptor	0	19	5	28
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	5	0	0	5
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
USP1 protein, partial	32	0	0	32
DNA polymerase beta	4	0	0	4
Alpha-synuclein	7	6	0	13
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	22	0	0	22
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	4
Glutamate receptor ionotropic, NMDA 1	0	8	4	18
Proton-coupled amino acid transporter 1	0	9	0	10
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	6
Mineralocorticoid receptor	1	11	6	20
Mineralocorticoid receptor	0	4	0	4
Solute carrier organic anion transporter family member 1A1	0	4	0	6
Guanine nucleotide-binding protein G	9	0	0	9
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	25	0	0	25
Chain B, HADH2 protein	25	0	0	25
acid sphingomyelinase	1	0	0	1
glucocerebrosidase	10	0	0	10
alpha-galactosidase	5	0	0	5
Bloom syndrome protein isoform 1	23	0	0	23
lysosomal alpha-glucosidase preproprotein	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
huntingtin isoform 2	6	0	0	6
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	13	0	16
Prothrombin	0	2	2	4
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	2	0	8
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	4
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Adenosine receptor A2a	0	8	1	9
Trypsin-3	0	1	0	1
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	6	0	6
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	21	0	21
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	9	0	13
Solute carrier family 22 member 2	0	10	0	13
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
peripheral myelin protein 22 isoform 1	17	0	0	17
potassium voltage-gated channel subfamily H member 2 isoform d	21	0	0	21
transcriptional regulator ERG isoform 3	11	0	0	11
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
Sterol O-acyltransferase 1	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Aromatase	0	1	1	2
Thromboxane-A synthase	0	5	0	5
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Delta-type opioid receptor	0	6	2	10
Amine oxidase [flavin-containing] A	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	6
Estrogen receptor	1	28	9	40
Estrogen receptor beta	1	14	9	25
interleukin 8	14	0	0	14
mitogen-activated protein kinase 1	17	0	0	17
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	28	0	0	28
neuropeptide S receptor isoform A	11	0	0	11
Beta-glucuronidase	0	3	0	3
Cholinesterase	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	1	4
Testosterone 17-beta-dehydrogenase 3	0	3	0	3
Chain A, retinol dehydratase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	6	0	6
DNA polymerase kappa isoform 1	19	0	0	19
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
67.9K protein	14	0	0	14
Nicotinate phosphoribosyltransferase	0	4	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
phosphopantetheinyl transferase	26	0	0	26
NFKB1 protein, partial	7	0	0	7
flap endonuclease 1	11	0	0	11
muscarinic acetylcholine receptor M1	21	0	0	21
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
vitamin D3 receptor isoform VDRA	29	0	0	29
Translocator protein	0	3	2	5
Vasopressin V2 receptor	0	2	1	4
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	4	2	6
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	1	1	2
PPM1D protein	10	0	0	10
thioredoxin glutathione reductase	10	0	0	10
Neutral amino acid transporter A	0	5	0	5
Neutral amino acid transporter B(0)	0	5	0	5
Carbonic anhydrase-like protein, putative	0	0	0	10
Amino acid transporter	0	5	0	5
Chain A, Ferritin light chain	18	0	0	18
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	6	4	16
Glutamate receptor ionotropic, NMDA 2B	0	7	4	17
Glutamate receptor ionotropic, NMDA 2C	0	6	4	16
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Glutamate receptor ionotropic, NMDA 2D	0	6	4	16
Glutamate receptor ionotropic, NMDA 3B	0	6	4	16
Glutamate receptor ionotropic, NMDA 3A	0	6	4	16
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	4	0	0	4
cytochrome P450 2D6	33	0	0	33
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	9	0	9
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	5	1	1	7
Myeloperoxidase	0	5	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	5	1	1	7
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	5	1	11
Adenosine receptor A2a	0	3	1	9
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	20	1	21
Sigma non-opioid intracellular receptor 1	0	2	1	3
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	7	0	7
ATP-dependent translocase ABCB1	0	15	1	19
Insulin receptor	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Histone deacetylase 1	0	1	0	1
Histone deacetylase 2	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	7	0	12
Histone deacetylase 6	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	7
Solute carrier organic anion transporter family member 1B1	0	10	0	15
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
galanin receptor type 3	0	1	0	1
ORF73	0	0	2	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	3	0	0	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	15	0	0	15
apical membrane antigen 1, AMA1	10	0	0	10
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Genome polyprotein	0	2	2	4
Fumarate hydratase	11	0	0	11
polyprotein	11	0	0	11
D(1A) dopamine receptor	12	0	0	12
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
5-hydroxytryptamine receptor 4	0	28	1	29
ATP-dependent translocase ABCB1	0	4	0	4
Beta-1 adrenergic receptor	0	11	2	13
5-hydroxytryptamine receptor 1A	0	5	2	7
Alpha-2A adrenergic receptor	0	29	3	33
D(2) dopamine receptor	0	22	2	25
Alpha-2B adrenergic receptor	0	28	2	31
Alpha-2C adrenergic receptor	0	21	3	25
D	0	9	0	9
D(3) dopamine receptor	0	9	0	9
Alpha-2B adrenergic receptor	0	10	1	11
ATP-dependent translocase ABCB1	0	4	1	5
D(1A) dopamine receptor	0	21	1	23
Alpha-2C adrenergic receptor	0	10	1	11
Alpha-2A adrenergic receptor	0	10	1	11
Alpha-1D adrenergic receptor	0	18	2	21
D(1B) dopamine receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	26	2	28
5-hydroxytryptamine receptor 2C	0	28	2	30
D(4) dopamine receptor	0	6	0	6
D(3) dopamine receptor	0	25	0	26
5-hydroxytryptamine receptor 2B	0	32	1	33
5-hydroxytryptamine receptor 6	0	23	1	24
D(2) dopamine receptor	0	15	2	18
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
urokinase plasminogen activator surface receptor precursor	7	0	0	7
relaxin receptor 1 isoform 1	2	0	0	2
relaxin receptor 2 isoform 1	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Cytochrome P450 2C19	0	12	0	12
Kappa-type opioid receptor	0	5	2	8
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	1	3
Vitamin D3 receptor	0	1	1	2
Transporter	0	2	0	2
Vitamin D3 receptor A	0	0	2	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	12	0	0	12
Metallo-beta-lactamase type 2	0	1	1	2
M-phase phosphoprotein 8	17	0	0	17
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	3	1	4
Angiotensin-converting enzyme	0	18	0	19
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	1	3
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	5	4	10
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	3	5
Beta-lactamase class B VIM-2	0	1	1	2
Vpr	3	0	0	3
Albumin	0	0	7	7
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	4
Cytochrome P450 2B6	0	3	1	5
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Cytochrome P450 2E1	0	2	0	2
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase	0	4	0	10
bromodomain adjacent to zinc finger domain 2B	16	0	0	16
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	3	0	3
Snq2p	0	0	0	4
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
cellular tumor antigen p53 isoform a	6	0	0	6
histone deacetylase 9 isoform 3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
Proteasome subunit alpha type-7	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
Transmembrane protease serine 2	0	1	3	4
Glutamate receptor ionotropic, NMDA 2D	0	3	1	4
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Potassium channel subfamily K member 2	0	1	1	2
Albumin	0	6	4	10
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	8	0	8
Procathepsin L	0	2	3	5
Aldo-keto reductase family 1 member B1	0	28	0	28
Muscarinic acetylcholine receptor M2	0	15	1	16
Muscarinic acetylcholine receptor M4	0	13	0	13
Muscarinic acetylcholine receptor M1	0	4	1	5
Muscarinic acetylcholine receptor M3	0	4	1	5
Muscarinic acetylcholine receptor M4	0	4	1	5
Muscarinic acetylcholine receptor M5	0	4	1	5
Muscarinic acetylcholine receptor M5	0	13	0	13
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	2	4
Muscarinic acetylcholine receptor M2	0	4	1	5
Muscarinic acetylcholine receptor M1	0	15	1	16
Sphingomyelin phosphodiesterase	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	19	1	20
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	12	0	12
D(4) dopamine receptor	0	8	0	9
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-1D adrenergic receptor	0	10	1	11
Sodium-dependent noradrenaline transporter	0	28	0	28
Sodium-dependent dopamine transporter	0	6	0	6
Histamine H2 receptor	0	19	2	21
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	4	0	4
Histamine H1 receptor	0	3	4	7
Melanocortin receptor 4	0	4	0	4
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	4	0	8
5-hydroxytryptamine receptor 7	0	6	1	7
Histamine H1 receptor	0	12	3	15
Sodium channel protein type 1 subunit alpha	0	1	0	1
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Melanocortin receptor 3	0	4	0	4
Histamine H2 receptor	11	2	3	16
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	5	0	0	5
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit alpha type-6	0	0	2	3
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Aldehyde oxidase	0	5	0	7
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Glutamate receptor ionotropic, NMDA 2C	0	3	1	4
Nuclear receptor subfamily 3 group C member 3	0	16	0	16
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	4	2	6
Sodium channel protein type 10 subunit alpha	0	1	0	1
Luciferase	18	0	0	18
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Glycine receptor subunit alpha-1	0	0	4	4
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Phospholipase A2	0	0	1	1
G-protein coupled bile acid receptor 1	0	1	0	1
Bile acid receptor	0	1	1	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	7	0	11
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	3	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	3	0	4
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	6	0	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	3	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Solute carrier family 22 member 6	0	3	0	5
Multidrug and toxin extrusion protein 2	0	4	0	4
Solute carrier family 22 member 8	0	5	0	7
Multidrug and toxin extrusion protein 1	0	9	0	9
Histamine H4 receptor	0	3	2	5
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
5-hydroxytryptamine receptor 3E	0	2	1	3
5-hydroxytryptamine receptor 3B	0	2	1	3
Beta-2 adrenergic receptor	0	5	3	9
Beta-3 adrenergic receptor	0	10	2	12
Dipeptidyl peptidase 4	0	1	0	1
Alpha-1A adrenergic receptor	0	4	3	8
Alpha-1B adrenergic receptor	0	2	2	5
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 4	0	1	1	2
Neutral alpha-glucosidase AB	0	1	0	1
5-hydroxytryptamine receptor 3D	0	2	1	3
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	1	3
Heparanase	0	0	1	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	1	0	2
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
cytochrome P450 2C9 precursor	4	0	0	4
Sigma intracellular receptor 2	0	1	0	1
GALC protein	11	0	0	11
Solute carrier family 22 member 3	0	4	0	5
Solute carrier family 22 member 3	0	2	0	2
C-8 sterol isomerase	0	5	0	5
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	6	1	7
endonuclease IV	10	0	0	10
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
D(2) dopamine receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Transporter	0	3	0	3
Progesterone receptor	0	15	7	25
Adenosine receptor A2b	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
RAD51	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	4	1	10
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	1	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Steryl-sulfatase	0	3	0	4
Multidrug resistance-associated protein 1	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Solute carrier organic anion transporter family member 1A3	0	1	0	4
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	1	0	4
Peroxisome proliferator-activated receptor alpha	2	1	1	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
serine/threonine-protein kinase PLK1	4	0	0	4
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	1	3	4
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Adenosine receptor A1	0	7	0	7
Estrogen-related receptor gamma	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	1	1	0	2
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	3	0	3
Cysteinyl leukotriene receptor 1	0	2	0	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
Progesterone receptor	0	1	0	1
Glucocorticoid receptor	0	3	2	6
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	1	3	4
Cannabinoid receptor 2	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Neuropeptide FF receptor 2	0	0	0	2
ALK tyrosine kinase receptor	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 7	0	0	0	3
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	2	0	2
Chain A, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
Prothrombin	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Acetylcholinesterase	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120	0	1	0	1
Protease	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	0	0	1
Reverse transcriptase	0	1	1	2
Cholesterol 24-hydroxylase	0	1	1	2
Ornithine decarboxylase	0	1	0	1
Mitochondrial 2-oxodicarboxylate carrier	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	2	0	2
protein AF-9 isoform a	0	0	0	1
Endothelin-1 receptor	0	2	1	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
eyes absent homolog 2 isoform a	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	7	5	12
Cytochrome P450 1B1	0	2	0	2
Ghrelin O-acyltransferase	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	2	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Polyphenol oxidase 2	0	5	0	9
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	2	0	0	2
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	3	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	3	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	5
Gamma-aminobutyric acid receptor subunit beta-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Cocaine esterase	0	1	0	2
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	1	3
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	1	3
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	10	0	11
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Pancreatic alpha-amylase	0	1	0	1
Beta-glucuronidase	0	2	0	2
High mobility group protein B1	0	0	2	2
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
High mobility group protein B1	0	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 2	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Corticotropin-releasing factor receptor 1	0	3	0	3
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	3	0	3
Histamine H1 receptor	0	3	1	4
Carbonic anhydrase	0	1	0	8
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	1	0	8
Carbonic anhydrase	0	1	0	8
Carbonic anhydrase	0	1	0	8
Carbonic anhydrase	0	1	0	8
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	1	0	4
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	7	0	0	7
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	2	0	2
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	2	7	10
Aldo-keto reductase family 1 member C3	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	4	0	4
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	7	0	7
Cytochrome P450 2A6	0	2	0	2
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	1	2	5
Beta-2 adrenergic receptor	0	4	1	6
Beta-1 adrenergic receptor	0	5	2	9
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Beta-1 adrenergic receptor	0	2	1	3
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	2	3	6
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	3
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
DNA polymerase eta isoform 1	4	0	0	4
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	2	0	2
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	0	2
Gonadotropin-releasing hormone receptor	0	3	1	4
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Lanosterol 14-alpha demethylase	0	5	1	6
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
Gonadotropin-releasing hormone receptor	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	2	0	0	2
Tyrosine-protein kinase Lck	0	2	0	2
Tyrosinase	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
phosphoglycerate kinase	2	0	0	2
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
PINK1	3	0	0	3
Cytochrome P450 1A2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	4	0	4
Dihydrofolate reductase	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
Cystathionine gamma-lyase	0	2	0	2
Serine racemase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Chain A, PROGESTERONE RECEPTOR	0	1	0	1
Glucocorticoid receptor	0	1	0	1
Tegument protein VP16	0	0	1	1
Glucocorticoid receptor	0	1	1	2
Coagulation factor VII	0	1	0	1
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Tissue factor	0	1	0	1
Progesterone receptor	0	0	1	1
Glucocorticoid receptor	0	1	0	1
serine-protein kinase ATM isoform a	1	0	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Histidine decarboxylase	0	0	2	2
Delta-type opioid receptor	0	5	3	8
Kappa-type opioid receptor	0	3	1	5
Kappa-type opioid receptor	0	3	3	6
Mu-type opioid receptor	0	3	1	6
Sigma non-opioid intracellular receptor 1	0	3	1	4
UDP-glucuronosyltransferase 1A8	0	0	0	3
Nociceptin receptor	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Estrogen receptor	0	0	2	3
Estrogen receptor beta	0	0	2	3
BRCA1	1	0	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
C-terminal-binding protein 1	1	0	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Translocator protein	0	2	1	4
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Glutamate 5-kinase	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	3	3	6
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	2	4
Cholecystokinin receptor type A	0	2	0	2
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
interferon gamma precursor	0	0	0	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	2	0	2
Protein kinase C beta type	0	1	0	1
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Protein kinase C iota type	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Protein kinase C eta type	0	2	0	2
Emopamil-binding protein-like	0	2	0	2
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	2	0	2
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Transthyretin	0	1	0	3
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Genome polyprotein	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Carbonic anhydrase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Adrenal Hyperplasia, Congenital

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (2,895)

Protein Targets (1,571)

Adrenal Hyperplasia, Congenital

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (2,895)

Drugs Studied (390)

Protein Targets (1,571)