Dupuytren's Contracture

Synonym
Dupuytren's Contracture
Dupuytren's Disease
Fibromatosis, Palmar

Excerpt	Reference
"Dupuytren's contracture is represented by a proliferation of fibroblasts."	( Katenkamp, D; Stiller, D, 1976)
"Dupuytren's contracture is a deforming, fibrotic condition of the palmar fascia which has confounded clinicians and scientists since the early descriptions by Guillaume Dupuytren in 1831."	( Murrell, GA, 1992)
"The pathogenesis of Dupuytren's contracture is cited, with emphasis on the development of the contracture at various sites."	( Leibovic, SJ; Strickland, JW, 1991)
"The treatment of Dupuytren's contracture is still controversial."	( Chick, LR; Lister, GD, 1991)
"Dupuytren's disease is a relatively rare occurrence in a patient of the black race."	( Antoine, GA; LeFlore, I, 1991)
"A case of Dupuytren's Disease is presented in which a combination of dermofasciectomy and proximal interphalangeal joint replacement using a Swanson's prosthesis improved hand function and avoided further digit amputation."	( Lennon, WP; Tonkin, MA, 1985)
"Nodular palmar fibromatosis is a self-limited proliferation of fibro-/myofibroblasts associated with growth factor synthesis and abundant fibronectin extracellular matrix deposition."	( Berndt, A; Celeda, D; Gabler, U; Katenkamp, D; Kosmehl, H; Luo, X; Mandel, U; Zardi, L, 1995)
"Dupuytren's disease is associated with contraction of specialized fibroblasts present in the diseased palmar fascia."	( Parizi, M; Rayan, GM; Tomasek, JJ, 1996)
"Dupuytren's disease is characterized clinically by a proliferative fibrous contracture of the palmar or digital fascia."	( Holland, AJ; McGrouther, DA, 1997)
"Dupuytren's disease is a proliferative disease with contractile properties, prone to recur after surgery."	( Grobbelaar, AO; Jemec, B; Linge, C; McGrouther, DA; Sanders, R; Smith, PJ, 2000)
"Dupuytren's contracture is a fibroproliferative disorder that is associated with increased collagen deposition."	( Ko, F; Kuhn, MA; Payne, WG; Robson, MC; Wang, X, 2002)
"Dupuytren's disease is a benign fibroproliferative disease of unknown aetiology."	( Alansari, A; Bayat, A; Ferguson, MW; Ollier, WE; Shah, M; Stanley, JK; Watson, JS, 2002)
"Dupuytren's disease is a palmar fibromatosis bringing about irreversible finger contracture."	( Bobiński, R; Kasperczyk, M; Koźma, EM; Olczyk, K; Szpyra, K, 2002)
"The contracture of Dupuytren's disease is a notable example."	( Badalamente, MA; Hentz, VR; Hurst, LC, 2002)
"Dupuytren's contracture is a common hand problem."	( Denkler, K, 2005)
"Dupuytren's disease is not as commonly reported in women as in men."	( Al Ghazal, SK; Anwar, MU; Boome, RS, 2007)
"Dupuytren's disease is less prevalent in women but its symptomatic presentation is similar to that in men, with more severe involvement of the PIP joint and a similar recurrence rate."	( Al Ghazal, SK; Anwar, MU; Boome, RS, 2007)
"Dupuytren's contracture is a benign fibromatosis leading to complex remodeling of the palmar fascia structure and properties."	( Ciecierska, M; Głowacki, A; Koźma, EM; Olczyk, K, 2007)
"Dupuytren's disease is very common, with a prevalence of up to 40% in the Scandinavian population."	( De Smet, L; Degreef, I; Steeno, P, 2008)
"Dupuytren's disease is a common fibroproliferative condition of the hand characterized by fibrotic lesions (nodules and cords), leading to disability through progressive digital contracture."	( Cambrey, AD; Grobbelaar, AO; Khaw, PT; Townley, WA, 2008)
"Dupuytren's disease is a progress fibromatosis of unknown origin first described in 1831."	( Knobloch, K; Redeker, J; Vogt, PM, 2009)
"Dupuytren's disease is a fibroproliferative condition involving the superficial palmar fascia, leading to a progressive and irreversible flexion of the fingers."	( Cordova, A; Moschella, F; Tripoli, M, 2011)
"Dupuytren's disease is a progressive fibroproliferative disorder which can result in fixed flexion contractures of digits and impaired hand function."	( Barrett, E; Chojnowski, AJ; Jerosch-Herold, C; Larson, D; Shepstone, L; Vaughan, SP, 2011)
"Dupuytren's contracture is a disease of unknown etiology, leading with time to decreased hand function caused by increasing contracture of fingers."	( Bednarek, M; Budzyński, P; Gniadek, M; Trybus, M; Wiśniowski, Z, 2012)
"Dupuytren's disease is a disorder of the palmar aponeurosis responsible for apparition of pathological collagen cords that will gradually lead to a digital retraction."	( Camuzard, O; Chignon-Sicard, B; Dumas, P; Dumontier, C; Foissac, R, 2013)
"Dupuytren's disease is a benign fibromatosis affecting the palmar and digital fascia and causing flexion contracture of the affected fingers."	( Cuylits, N, 2013)
"Dupuytren's disease is a fibro-proliferative disease characterized by a disorder of the extracellular matrix (ECM) and high myofibroblast proliferation."	( Alaminos, M; Alfonso-Rodríguez, CA; Campos, A; Carriel, V; Garrido-Gómez, J; Garzón, I; Hernández-Cortés, P; Martín-Piedra, MÁ; Oliveira, AC; Scionti, G, 2014)
"Dupuytren's contracture is not a known side effect of BRAF inhibitor treatment."	( Chan, SW; Vorobiof, DA, 2015)
"Dupuytren's disease is a common fibrotic disorder of the palm characterized by the development of progressive flexion deformities in the digits, leading to significant functional impairment."	( Ball, C; Chan, J; Izadi, D; Nanchahal, J; Verjee, LS, 2016)
"Dupuytren's contracture is a fibroproliferative disorder affecting the palmar fascia of the hand."	( Borgschulze, A; Grotheer, V; Krassovka, J; Lögters, T; Sahlender, B; Windolf, J, 2019)
"Dupuytren's disease is a benign fibroproliferative disorder of the hand that results in disabling digital contractures that impair function and diminish the quality of life."	( Beredjiklian, PK; Chen, Y; Feldman, GJ; Fertala, A; Fertala, J; Rajpar, I; Rivlin, MR; Ruggiero, NA; Steplewski, A; Tomlinson, RE; Wang, ML, 2022)
"Dupuytren's disease is a progressive hand disorder characterized by the formation of pathologic nodules and cords in the palm, often leading to progressive flexion contractures."	( De Ketele, A; Degreef, I, 2023)
"Dupuytren's disease is a fibroproliferative disease that affects the palmar hand, causing progressive, permanent, and symptomatic flexion contracture of the digits."	( Choi, JY; Choi, YJ; Jung, SN; Lee, J; Seo, BF, 2023)

Excerpt	Reference
"Although palmar fibromatosis has no defined mutations, its prevalence has been linked to the prevalence of Y-Chromosome Haplogroup I that expanded after the Last Ice Age, thus making th distribution of all three "Celtic" diseases dependent on the global climate from 40 to 8 Kya."	( Kurbel, S, 2019)

Excerpt	Reference
"Two groups of patients with Dupuytren's disease were treated by limited fasciectomy."	( Ward, CM, 1976)
"Surgical treatment of Dupuytren's contracture improves function but cannot remove the cause of the disease."	( Deutschmann, W, 1975)
"Treatment of 129 patients with palmar fibromatosis was performed; all the men were from 20 to 63 years old."	( Savchenko, VI; Tsarev, NI, 1992)
"Although not systemic or lethal, poorly treated Dupuytren's contracture can lead to significant morbidity and long-term disability."	( Paul, H; Watson, HK, 1991)
"Finally, Dupuytren's disease presenting with no contracture can be managed effectively and conservatively by a series of intralesional injections of triamcinolone into the nodules and cords, the treatment of choice for all plantar nodules and knuckle pads."	( Ketchum, LD, 1991)
"In the surgical treatment of Dupuytren's disease a tissue adhesive, Tissucol (Immuno, Heidelberg), has been used rather than vacuum drainage to reduce postoperative haematoma formation."	( Eide, E; Jurgeit, H, 1985)
"Digital contractures caused by Dupuytren's disease can best be treated by open fasciotomy plus excision of all overlying involved skin and replacement by full-thickness skin grafts."	( Gonzalez, RI, 1985)
"Out-patient interventions for Dupuytren's disease, ganglia and trigger digits result in significant cost savings over formal surgical treatment."	( Stothard, J; Webb, JA, 2009)
"A plantar or palmar fibromatosis was observed in five of 53 patients treated with vemurafenib."	( De Kock, J; Grosber, M; Gutermuth, J; Neyns, B; Vandersleyen, V; Wilgenhof, S, 2016)
"Trigger digit, Dupuytren's disease, and ganglion cysts are 3 common disorders treated by hand surgeons."	( Avery, EC; McCabe, SJ, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	327 (48.59)	23.3326
1990's	94 (13.97)	12.5806
2000's	91 (13.52)	18.1394
2010's	117 (17.38)	28.8240
2020's	44 (6.54)	9.53

Drug	Relationship Strength	Studies	Trials
carbamates	low	1	0
carnitine	low	1	0
chlorine	low	1	0
dimethyl sulfoxide	low	4	0
formaldehyde	low	1	0
formamide	low	1	0
iodine	low	1	0
niacin	low	1	0
4-aminobenzoic acid	low	2	0
uric acid	low	5	0
phenytoin	low	2	0
acetaminophen	medium	1	1
aspirin	low	1	0
bendroflumethiazide	medium	1	1
bupivacaine	medium	5	1
verapamil	low	1	0
carbamazepine	low	2	0
carisoprodol	low	1	0
clonidine	low	2	0
diazepam	low	1	0
flucytosine	low	1	0
fluorouracil	medium	3	1
furazolidone	low	1	0
gentamicin	low	1	0
glyphosate	low	1	0
guanethidine	medium	2	1
lidocaine	medium	15	3
isoflurane	low	1	0
isoniazid	low	2	0
isoproterenol	low	1	0
khellin	low	16	0
labetalol	low	1	0
mepivacaine	low	4	0
meprobamate	low	1	0
metformin	low	2	0
metoprolol	low	1	0
midazolam	low	1	0
ml 7	low	1	0
nifedipine	low	1	0
nitroglycerin	low	1	0
oxyphenbutazone	low	1	0
phenobarbital	low	7	0
primidone	low	2	0
procaine	low	1	0
propranolol	low	1	0
tiopronin	low	3	0
tolbutamide	low	1	0
hydrocortisone acetate	low	1	0
prednisolone	low	1	0
estriol	low	2	0
hydroxyproline	low	6	0
prednisone	low	1	0
methylprednisolone acetate	low	1	0
androsterone	low	1	0
etiocholanolone	low	1	0
bromodeoxyuridine	low	1	0
carbostyril	low	1	0
phenylephrine	low	1	0
tyrosine	low	1	0
cysteamine	low	1	0
methylene blue	low	1	0
leucine	low	1	0
colchicine	low	4	0
cycloserine	low	1	0
triamcinolone acetonide	medium	7	4
phencyclidine	low	1	0
methylprednisolone	low	4	0
thiophenes	low	1	0
hydrazine	low	5	0
methysergide	low	1	0
dihydrotestosterone	low	1	0
copper gluconate	low	1	0
acetylcysteine	low	2	0
dehydroepiandrosterone sulfate	low	1	0
d-alpha tocopherol	medium	23	1
tocopherols	low	1	0
streptomycin	low	1	0
galactose	low	1	0
trolamine salicylate	low	19	0
osmium tetroxide	low	1	0
triamcinolone	medium	9	1
timolol	low	1	0
substance p	low	1	0
pirfenidone	low	1	0
desflurane	low	1	0
colforsin	low	1	0
metsulfuron methyl	low	1	0
simvastatin	low	1	0
imiquimod	low	2	0
acridine orange	low	1	0
delphinidin	low	2	0
nicotine	low	1	0
fibrinogen	low	5	0
arginyl-glycyl-aspartic acid	low	1	0
cyanates	low	1	0
pyridinoline	low	3	0
marimastat	low	1	0
delta-hydroxylysylnorleucine	low	1	0
5,5'-dihydroxylysylnorleucine	low	1	0
ilomastat	low	2	0
naproxen	medium	1	1
angiotensin ii	low	1	0
organophosphonates	low	1	0
sorafenib	low	1	0
cortisone	low	9	0
glycogen	low	1	0
fibrin	medium	2	1
glucosamine	low	1	0
elastin	low	3	0
cefoxitin	low	1	0
tretinoin	low	1	0
keratan sulfate	low	1	0
allylthiourea	low	1	0
thiourea	low	1	0
tamoxifen	medium	4	1
ethionamide	low	1	0
thiopental	low	1	0
dermatan sulfate	low	4	0
hydroxylysine	low	3	0
blister	low	1	0
alpha-chymotrypsin	low	3	0
sphingosine	low	1	0
dinoprostone	low	3	0
dinoprost	low	3	0
alprostadil	low	1	0
amphotericin b	low	1	0
coenzyme q10	low	1	0
sphingosine 1-phosphate	low	1	0
clobetasol	low	2	0
arsenic	low	2	0
indinavir sulfate	low	1	0
phosphorus	low	1	0
radium	low	3	0
acid phosphatase	low	3	0
vendex	low	1	0
ubiquinone	low	1	0
chitosan	low	1	0
mesna	low	1	0
sodium ethylxanthate	low	1	0
cardiovascular agents	low	1	0
plx4032	low	3	0
thymosin	low	1	0
heparitin sulfate	low	1	0
warfarin	low	2	0
epidermal growth factor	low	4	0
transforming growth factor beta	low	23	0
rome	low	1	0
hyaluronoglucosaminidase	low	9	0
transforming growth factor alpha	low	1	0
cytochalasin d	low	3	0
orabase	low	1	0
chondroitin sulfates	low	3	0
hypoxanthine	low	1	0
allopurinol	low	2	0

Protein Targets (1,689)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	21	0	0	21
Genome polyprotein	0	0	1	1
USP1 protein, partial	20	0	0	20
AR protein	57	0	0	57
thyroid stimulating hormone receptor	21	0	0	21
glucocorticoid receptor [Homo sapiens]	42	0	0	42
retinoic acid nuclear receptor alpha variant 1	38	0	0	38
estrogen nuclear receptor alpha	54	0	0	54
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	26	0	0	26
Histone H2A.x	8	0	0	8
chromobox protein homolog 1	29	0	0	29
transcriptional regulator ERG isoform 3	6	0	0	6
geminin	40	0	0	40
Polyphenol oxidase 2	0	5	0	7
Cellular tumor antigen p53	26	0	0	26
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
RAR-related orphan receptor gamma	31	0	0	31
ATAD5 protein, partial	13	0	0	13
GLS protein	14	0	0	14
Microtubule-associated protein tau	20	0	0	20
Smad3	11	0	0	11
aldehyde dehydrogenase 1 family, member A1	26	0	0	26
nuclear receptor subfamily 1, group I, member 3	26	0	0	26
progesterone receptor	25	0	0	25
EWS/FLI fusion protein	21	0	0	21
retinoid X nuclear receptor alpha	26	0	0	26
estrogen-related nuclear receptor alpha	39	0	0	39
peroxisome proliferator activated receptor gamma	22	0	0	22
aryl hydrocarbon receptor	18	0	0	18
thyroid hormone receptor beta isoform 2	25	0	0	25
peripheral myelin protein 22	19	0	0	19
cytochrome P450 3A4 isoform 1	20	0	0	20
Gamma-aminobutyric acid receptor subunit pi	20	7	4	31
ATP-binding cassette sub-family C member 3	0	32	0	32
Multidrug resistance-associated protein 4	0	33	0	36
Solute carrier family 22 member 6	0	6	0	6
Carbonic anhydrase 12	0	2	0	3
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	10	0	10
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Bile salt export pump	0	49	0	49
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	7	0	8
Carbonic anhydrase 2	0	7	0	8
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	7	1	9
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 3	0	2	0	3
Cytochrome P450 3A4	0	14	2	17
Cytochrome P450 2D6	0	8	1	9
Cytochrome P450 2C9	0	18	2	20
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	20	7	4	31
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	20	7	4	31
Gamma-aminobutyric acid receptor subunit gamma-2	20	7	4	31
UDP-glucuronosyltransferase 1-6	0	2	0	3
Glutamate receptor 2	17	0	0	17
Gamma-aminobutyric acid receptor subunit alpha-5	20	7	4	31
Gamma-aminobutyric acid receptor subunit alpha-3	20	7	4	31
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Carbonic anhydrase 4	0	4	0	5
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	20	7	4	31
Gamma-aminobutyric acid receptor subunit alpha-2	20	7	4	31
Gamma-aminobutyric acid receptor subunit alpha-4	20	7	4	31
Gamma-aminobutyric acid receptor subunit gamma-3	20	7	4	31
Gamma-aminobutyric acid receptor subunit alpha-6	20	7	4	31
Carbonic anhydrase 5A, mitochondrial	0	2	0	3
Prostaglandin G/H synthase 2	0	7	1	9
Carbonic anhydrase 7	0	3	0	4
Nuclear receptor ROR-gamma	11	1	1	13
Cytochrome P450 2J2	0	9	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	20	8	4	32
Gamma-aminobutyric acid receptor subunit beta-3	20	7	4	31
Gamma-aminobutyric acid receptor subunit beta-2	20	7	4	31
Carbonic anhydrase 9	0	3	0	4
GABA theta subunit	20	7	4	31
Canalicular multispecific organic anion transporter 1	0	31	0	31
Carbonic anhydrase 15	0	3	0	4
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	20	7	4	31
Carbonic anhydrase 14	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	2	0	3
toxin B	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	14	0	0	14
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	2	0	0	2
pregnane X receptor	12	0	0	12
phosphopantetheinyl transferase	14	0	0	14
NFKB1 protein, partial	7	0	0	7
Thrombopoietin	4	0	0	4
regulator of G-protein signaling 4	22	0	0	22
farnesoid X nuclear receptor	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
arylsulfatase A	14	0	0	14
euchromatic histone-lysine N-methyltransferase 2	35	0	0	35
Bloom syndrome protein isoform 1	12	0	0	12
D(1A) dopamine receptor	9	0	0	9
thyroid hormone receptor beta isoform a	10	0	0	10
heat shock protein beta-1	12	0	0	12
flap endonuclease 1	11	0	0	11
survival motor neuron protein isoform d	11	0	0	11
muscarinic acetylcholine receptor M1	15	0	0	15
Histone deacetylase 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Histone deacetylase 1	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	20	0	0	20
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	17	0	0	17
Telomerase reverse transcriptase	0	1	0	1
Amyloid-beta precursor protein	1	4	0	5
Reverse transcriptase/RNaseH	0	1	0	1
interleukin 8	8	0	0	8
TDP1 protein	42	0	0	42
estrogen receptor 2 (ER beta)	16	0	0	16
IDH1	17	0	0	17
ras-related protein Rab-9A	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
lamin isoform A-delta10	32	0	0	32
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	6	2	8
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	12	0	0	12
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	2
GLI family zinc finger 3	41	0	0	41
pregnane X nuclear receptor	34	0	0	34
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
vitamin D3 receptor isoform VDRA	19	0	0	19
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	4	2	6
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, Cruzipain	6	0	0	6
peroxisome proliferator-activated receptor delta	19	0	0	19
tumor necrosis factor	2	0	0	2
Cytochrome P450 2C19	0	5	1	6
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Aurora kinase B	0	1	2	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Chain A, retinol dehydratase	0	1	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Sex hormone-binding globulin	0	1	5	6
Corticosteroid-binding globulin	0	7	0	7
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Androgen receptor	0	9	1	10
Solute carrier organic anion transporter family member 1A1	0	2	0	3
G-protein coupled bile acid receptor 1	0	0	4	4
glucocerebrosidase	7	0	0	7
DNA polymerase kappa isoform 1	10	0	0	10
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Integrin beta-3	2	2	0	4
Integrin beta-1	0	1	0	1
Integrin alpha-V	0	1	0	1
Integrin alpha-IIb	2	2	0	4
Integrin alpha-5	0	1	0	1
Integrin beta-5	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thioredoxin reductase	24	0	0	24
hypothetical protein, conserved	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	25	0	0	25
cytochrome P450 2D6	14	0	0	14
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	9	0	0	9
lethal factor (plasmid)	6	0	0	6
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Epidermal growth factor receptor	0	6	2	8
Fatty acid-binding protein, liver	0	4	1	5
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	2	0	3
Adenosine receptor A2a	0	3	1	5
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	2	1	3
glp-1 receptor, partial	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	18	0	0	18
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	17	2	25
Glycine receptor subunit alpha-1	0	16	0	16
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	1	0	0	1
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	2	0	4
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Myosin-2 heavy chain, non muscle	0	1	0	1
Myosin-2 heavy chain	0	1	0	1
Myosin IC heavy chain	0	1	0	1
Myosin-9	0	1	0	1
Myosin-10	0	1	2	3
Unconventional myosin-X	0	1	0	1
Myosin-7	0	1	0	1
Unconventional myosin-Ib	0	1	0	1
Myosin-4	0	1	0	1
Myosin-14	0	1	0	1
Nonmuscle myosin heavy chain	0	1	0	1
Unconventional myosin-Va	0	1	0	1
Myosin heavy chain, non-muscle	0	1	0	1
Unconventional myosin-XV	0	1	0	1
cellular tumor antigen p53 isoform a	6	0	0	6
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
Thymidine kinase, cytosolic	0	3	0	5
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	2	0	2
Spike glycoprotein	8	0	1	9
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
ATPase family AAA domain-containing protein 5	15	0	0	15
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	3	4
Potassium channel subfamily K member 9	0	1	0	1
Fumarate hydratase	10	0	0	10
PPM1D protein	7	0	0	7
polyprotein	10	0	0	10
Interferon beta	22	0	0	22
Chain A, Beta-lactamase	13	0	0	13
mitogen-activated protein kinase 1	9	0	0	9
Vpr	3	0	0	3
Albumin	0	0	4	4
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	4
Cytochrome P450 2B6	0	2	1	3
Sodium channel protein type 4 subunit alpha	0	4	0	6
Sodium channel protein type 9 subunit alpha	0	5	0	5
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, serum paraoxonase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	11	0	0	11
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	1	2
Rap guanine nucleotide exchange factor 3	5	0	0	5
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Carbonic anhydrase	0	1	0	2
Chain A, Ferritin light chain	10	0	0	10
GALC protein	3	0	0	3
thyroid stimulating hormone receptor	10	0	0	10
activating transcription factor 6	11	0	0	11
peripheral myelin protein 22 isoform 1	6	0	0	6
M-phase phosphoprotein 8	7	0	0	7
5-hydroxytryptamine receptor 4	0	10	1	11
Muscarinic acetylcholine receptor M1	0	1	2	3
Muscarinic acetylcholine receptor M3	0	1	2	3
Muscarinic acetylcholine receptor M4	0	2	2	4
Muscarinic acetylcholine receptor M5	0	1	2	3
Muscarinic acetylcholine receptor M2	0	1	2	3
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
Beta-1 adrenergic receptor	0	1	6	9
Alpha-1B adrenergic receptor	0	0	2	2
cytochrome P450 2D6 isoform 1	9	0	0	9
cytochrome P450 2C19 precursor	5	0	0	5
cytochrome P450 2C9 precursor	6	0	0	6
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	8	0	12
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	4	0	4
5-hydroxytryptamine receptor 1A	0	4	0	4
Alpha-2A adrenergic receptor	0	10	4	15
Alpha-1B adrenergic receptor	0	13	1	14
Alpha-2B adrenergic receptor	0	7	2	10
Alpha-1A adrenergic receptor	0	2	2	4
Alpha-2C adrenergic receptor	0	4	4	9
D	0	1	0	1
D(3) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 1A	0	20	4	25
Alpha-2B adrenergic receptor	0	5	2	7
Amine oxidase [flavin-containing] A	0	2	0	2
Alpha-2C adrenergic receptor	0	5	2	7
Alpha-2A adrenergic receptor	0	5	2	7
Alpha-1D adrenergic receptor	0	8	1	9
Alpha-1D adrenergic receptor	0	8	4	13
D(1B) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
5-hydroxytryptamine receptor 1B	0	14	0	14
Adenosine receptor A2b	0	0	1	1
Alpha-2B adrenergic receptor	0	0	0	2
D(4) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	3	1	5
Alpha-1A adrenergic receptor	0	3	6	10
Alpha-1B adrenergic receptor	0	2	5	8
Alpha-1A adrenergic receptor	0	13	2	15
Histamine H2 receptor	7	0	1	8
5-hydroxytryptamine receptor 7	0	3	0	3
D(2) dopamine receptor	0	2	1	3
Mu-type opioid receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	3	0	4
Multidrug and toxin extrusion protein 1	0	6	0	6
Nischarin	0	1	0	1
Luciferase	14	0	0	14
endonuclease IV	6	0	0	6
PAX8	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
67.9K protein	6	0	0	6
nuclear receptor subfamily 0 group B member 1	0	2	0	2
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
steroidogenic factor 1	0	2	0	2
muscleblind-like protein 1 isoform 1	8	0	0	8
neuropeptide S receptor isoform A	3	0	0	3
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	1	0	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	14	2	27
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	2	3
ATP-dependent translocase ABCB1	0	3	0	4
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
G	15	0	0	15
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
Solute carrier family 2, facilitated glucose transporter member 1	0	0	1	1
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Adenylate cyclase type 1	0	1	1	2
Inositol hexakisphosphate kinase 1	15	0	0	15
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
cytochrome P450 2C9, partial	15	0	0	15
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	5	2	8
Glutamate receptor ionotropic, NMDA 2A	0	4	2	7
Glutamate receptor ionotropic, NMDA 2B	0	4	2	7
Glutamate receptor ionotropic, NMDA 2C	0	4	2	8
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	2	7
Proton-coupled amino acid transporter 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3B	0	4	2	7
Glutamate receptor ionotropic, NMDA 3A	0	4	2	7
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	0	0	1
Multidrug resistance-associated protein 1	0	2	1	5
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Vascular endothelial growth factor receptor 2	0	4	2	7
Alpha-synuclein	3	3	0	6
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
Gamma-aminobutyric acid	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	5	9
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Neuronal acetylcholine receptor subunit alpha-4	1	3	2	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Neuronal acetylcholine receptor subunit beta-2	1	3	2	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
thyrotropin-releasing hormone receptor	4	0	0	4
Progesterone receptor	0	1	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	2	1	3
Mineralocorticoid receptor	0	3	1	4
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	4	2	8
Aromatase	0	3	0	4
Androgen receptor	0	1	1	2
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	2	0	2
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	1	2
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Solute carrier family 22 member 2	0	2	0	4
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 6	0	1	0	4
Solute carrier family 22 member 7	0	0	0	2
Solute carrier family 22 member 8	0	2	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Estrogen receptor	0	6	1	8
Sodium-dependent serotonin transporter	0	9	1	10
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
DNA polymerase beta	5	0	0	5
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	2	0	0	2
Skn7p	0	0	0	2
nonstructural protein 1	6	0	0	6
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
serine/threonine-protein kinase PLK1	4	0	0	4
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
hemoglobin subunit beta	1	0	0	1
huntingtin isoform 2	3	0	0	3
Thymidylate synthase	0	1	0	2
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Glutamine synthetase	0	1	0	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Chain A, Purine-nucleoside Phosphorylase	0	1	0	1
Chain C, Xanthine dehydrogenase/oxidase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Disintegrin and metalloproteinase domain-containing protein 10	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 12	0	1	0	1
A disintegrin and metalloproteinase with thrombospondin motifs 4	0	2	0	2
Interstitial collagenase	0	4	0	5
72 kDa type IV collagenase	0	4	0	5
Stromelysin-1	0	4	0	4
Matrilysin	0	2	0	2
Matrix metalloproteinase-9	0	4	0	4
Neutrophil collagenase	0	3	0	3
Macrophage metalloelastase	0	2	0	2
Collagenase 3	0	2	0	3
Matrix metalloproteinase-14	0	2	0	2
Matrix metalloproteinase-15	0	2	0	2
Matrix metalloproteinase-16	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 9	0	1	0	1
Matrix metalloproteinase-26	0	2	0	2
Matrix metalloproteinase-17	0	1	0	1
A disintegrin and metalloproteinase with thrombospondin motifs 5	0	2	0	2
Histamine H2 receptor	0	6	0	6
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Gag-Pol polyprotein	0	2	0	2
Substance-K receptor	0	6	0	6
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Protease	0	3	1	6
Multidrug and toxin extrusion protein 2	0	1	0	1
Protease	0	2	1	3
Protease	0	1	0	1
histone deacetylase 9 isoform 3	3	0	0	3
Neuronal acetylcholine receptor subunit beta-2	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	5
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2A6	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
NPYLR7B	0	0	1	1
beta-2 adrenergic receptor	2	0	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Beta-2 adrenergic receptor	0	10	6	17
Beta-1 adrenergic receptor	0	12	5	17
Beta-2 adrenergic receptor	0	4	1	6
Beta-3 adrenergic receptor	0	7	5	12
D(2) dopamine receptor	0	6	1	7
Beta-1 adrenergic receptor	0	7	3	12
Beta-2 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	0	6	1	7
D(4) dopamine receptor	0	3	0	3
Beta-adrenergic receptor kinase 1	0	0	3	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	3	1	4
D(3) dopamine receptor	0	7	0	7
D(1A) dopamine receptor	3	0	0	3
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	1	6	9
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Sodium-dependent noradrenaline transporter	0	4	1	5
5-hydroxytryptamine receptor 2B	0	13	1	14
Sodium-dependent dopamine transporter	0	4	0	4
Heparanase	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Phospholipase A-2-activating protein	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	5	0	5
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 5	0	1	0	1
Chain A, Catalytic Domain of ADAMTS-5	0	1	0	1
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 5	0	1	0	1
Zinc metalloproteinase dpy-31	0	1	0	1
Zinc metalloproteinase dpy-31	0	1	0	1
ADAM10	0	1	0	1
disintegrin and metalloproteinase domain-containing protein 17 isoform 1 preproprotein	0	1	0	1
Matrix metalloproteinase-20	0	1	0	1
Tumor necrosis factor	0	1	0	1
Stromelysin-2	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Matrix metalloproteinase-25	0	1	0	1
Matrix metalloproteinase-24	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
thioredoxin glutathione reductase	5	0	0	5
caspase 7, apoptosis-related cysteine protease	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
luciferase	1	0	0	1
caspase-3	2	0	0	2
serine-protein kinase ATM isoform a	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
DNA polymerase III, partial	2	0	0	2
alpha-galactosidase	2	0	0	2
5-hydroxytryptamine receptor 2A	0	9	1	10
5-hydroxytryptamine receptor 2C	0	11	1	12
5-hydroxytryptamine receptor 6	0	7	1	8
UDP-glucuronosyltransferase 1A4	0	2	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
MO15-related protein kinase Pfmrk	0	1	0	1
Rho-associated protein kinase 1	0	1	2	3
Myosin light chain kinase, smooth muscle	0	2	2	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Caspase-1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Mu-type opioid receptor	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
Parkin	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
eyes absent homolog 2 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Muscarinic acetylcholine receptor M2	0	3	1	5
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Adenosine receptor A3	0	7	1	8
Muscarinic acetylcholine receptor M1	0	3	1	5
Phospholipase A2, membrane associated	0	0	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Muscarinic acetylcholine receptor M3	0	3	1	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Adenosine receptor A1	0	4	0	4
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
caspase recruitment domain family, member 15	0	1	0	1
Caspase-7	4	0	0	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
caspase-3	4	0	0	4
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Beta lactamase (plasmid)	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Transforming growth factor beta-1 proprotein	0	1	0	1
Mitogen-activated protein kinase 14	0	2	2	4
Mothers against decapentaplegic homolog 3	0	1	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	2	2
Serine/threonine-protein kinase PLK4	0	1	2	3
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pirin	0	1	0	1
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	1	2	3
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	1	2	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	1	2	3
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	2	2	4
GTPase KRas	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	3	2	6
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	1	2	3
Tyrosine-protein kinase Lck	0	2	2	4
Tyrosine-protein kinase Fyn	0	1	2	3
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	2	4
Insulin-like growth factor 1 receptor	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	1	2	3
Tyrosine-protein kinase HCK	0	1	2	3
Platelet-derived growth factor receptor beta	0	1	2	3
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	2	2	4
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	1	2	3
Fibroblast growth factor receptor 1	0	1	2	3
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	1	2	3
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	4	4	9
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Cyclin-dependent kinase 2	0	1	2	3
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	1	2	3
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Serine/threonine-protein kinase B-raf	0	2	0	2
Mitogen-activated protein kinase 1	0	2	2	4
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	1	2	3
Receptor-type tyrosine-protein kinase FLT3	0	2	2	4
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	1	2	3
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	1	2	3
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	1	2	3
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	1	2	3
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	1	2	3
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase 6	0	1	2	3
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
Heat shock factor protein 1	0	1	0	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	2	2	4
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	1	2	3
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Tyrosine-protein kinase Mer	0	1	2	3
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Serine/threonine-protein kinase ATR	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Cyclin-dependent kinase 10	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	1	2	3
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	1	2	3
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	1	2	3
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
luciferase	0	0	0	1
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	2	1	3
Mu-type opioid receptor	0	3	1	4
Vasopressin V1a receptor	0	1	1	2
Delta-type opioid receptor	0	3	1	4
Kappa-type opioid receptor	0	3	1	4
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Sphingosine kinase 2	0	3	0	3
Sphingosine kinase 1	0	2	0	2
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
melanocortin receptor 4	0	1	1	2
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Platelet-derived growth factor receptor beta	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Vascular endothelial growth factor receptor 1	0	1	1	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
G1/S-specific cyclin-D1	0	1	0	1
Protein kinase C eta type	0	1	1	2
Cyclin-C	0	1	1	2
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	1	1	2
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Serine/threonine-protein kinase mTOR	0	1	1	2
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
Cyclin-dependent kinase 8	0	1	1	2
Dual specificity protein kinase CLK3	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Protein delta homolog 1	0	0	1	1
Fatty-acid amide hydrolase 1	0	2	0	2
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C zeta type	0	1	1	2
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Serine/threonine-protein kinase D1	0	1	1	2
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	1	1	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	1	1	2
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	1	1	2
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	1	1	2
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	1	1	2
Serine/threonine-protein kinase PLK3	0	1	1	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	1	2
Serine/threonine-protein kinase Nek6	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	1	1	2
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
acid sphingomyelinase	1	0	0	1
apical membrane antigen 1, AMA1	2	0	0	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	2	2
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Estrogen receptor	0	0	2	3
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Estrogen receptor beta	0	0	2	3
Protein kinase C eta type	0	2	0	2
Protein kinase C theta type	0	2	0	2
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
Protein-arginine deiminase type-4	0	2	0	2
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	4	1	5
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, CES1 protein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
interferon gamma precursor	0	0	0	1
Transmembrane protease serine 2	0	0	1	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Procathepsin L	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	3	0	3
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease	0	2	0	3
Urease subunit alpha	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
60 kDa heat shock protein, mitochondrial	0	1	0	1
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
10 kDa heat shock protein, mitochondrial	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Carbonic anhydrase	0	0	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Context

Treatment

Research

Studies (673)

Protein Targets (1,689)

Dupuytren's Contracture

Synonyms(3)

Research Excerpts

Overview

Context

Treatment

Research

Studies (673)

Drugs Studied (177)

Protein Targets (1,689)