Page last updated: 2024-09-28

Tuberculosis, Avian

A variety of TUBERCULOSIS affecting various birds, including chickens and ducks. It is caused by MYCOBACTERIUM AVIUM and characterized by tubercles consisting principally of epithelioid cells.

Synonyms(1)

Synonym
Tuberculosis, Avian

Research

Studies (51)

TimeframeStudies, This Condition (%)All Conditions %
pre-199040 (78.43)23.3326
1990's5 (9.80)12.5806
2000's1 (1.96)18.1394
2010's2 (3.92)28.8240
2020's3 (5.88)9.53
DrugIndicatedRelationship StrengthStudiesTrials
betaine0low10
chlorine0low10
histamine0low20
pyrazinamide0low10
ciprofloxacin0low10
clofazimine0low10
gentamicin0low20
isoniazid0low110
aminosalicylic acid0low20
phenolphthalein0low10
corticosterone0low10
prednisone0low10
alanine0low10
aspartic acid0low10
lysine0low20
kanamycin a0low30
leucine0low10
cycloserine0low40
histidine0low10
valine0low10
arginine0low10
oxazoles0low20
thiazoles0low10
hematoxylin0low10
eosine yellowish-(ys)0low10
erythromycin0low20
ethambutol0low60
streptomycin0low70
dihydrostreptomycin sulfate0low10
etoposide0low10
marbofloxacin0low10
clarithromycin0low20
cobalt0low10
cyanates0low10
moxifloxacin0low10
retinol0low10
zithromax0low20
phenylthiourea0low10
D-fructopyranose0low10
ethionamide0low20
mycobactin0low20
bilirubin0low10
phosphorus0low10
rifamycins0low10
acid phosphatase0low10
cosyntropin0low10
ascorbic acid0low20
agar0low20
muramidase0low20
exudates0low10
rifampin0low20
3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin0low10

Protein Targets (515)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
DNA-directed RNA polymerase subunit beta0202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Carbonic anhydrase 10409
Carbonic anhydrase 204010
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0004
Glutamate receptor ionotropic, NMDA 1 0317
Proton-coupled amino acid transporter 10405
Adenosine deaminase0001
Carbonic anhydrase 40004
Chain A, 2-oxoglutarate Oxygenase5005
Microtubule-associated protein tau5005
thioredoxin glutathione reductase5005
Smad32002
euchromatic histone-lysine N-methyltransferase 2140014
microphthalmia-associated transcription factor isoform 90101
Tyrosine-protein phosphatase non-receptor type 10011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
thioredoxin reductase6006
phosphopantetheinyl transferase8008
NFKB1 protein, partial2002
GLS protein4004
thyroid stimulating hormone receptor9009
alpha-galactosidase1001
cytochrome P450 2C19 precursor2002
chromobox protein homolog 1100010
flap endonuclease 13003
DNA polymerase iota isoform a (long)5005
muscarinic acetylcholine receptor M12002
lethal factor (plasmid)5005
Cytochrome P450 3A40708
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
ATP-dependent phosphofructokinase3003
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase4004
RAR-related orphan receptor gamma100010
GLI family zinc finger 3130013
AR protein100010
cytochrome P450 family 3 subfamily A polypeptide 49009
glucocorticoid receptor [Homo sapiens]110011
retinoic acid nuclear receptor alpha variant 19009
estrogen-related nuclear receptor alpha100010
estrogen nuclear receptor alpha170017
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
IDH13003
nuclear factor erythroid 2-related factor 2 isoform 26006
thyroid hormone receptor beta isoform 2140014
nuclear factor erythroid 2-related factor 2 isoform 1110011
lethal(3)malignant brain tumor-like protein 1 isoform I2002
geminin110011
lamin isoform A-delta109009
Polyphenol oxidase 20506
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0303
Alpha-2B adrenergic receptor0011
Spike glycoprotein5005
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Ferritin light chain1001
aldehyde dehydrogenase 1 family, member A1100010
arylsulfatase A2002
Bloom syndrome protein isoform 12002
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0216
Glutamate receptor ionotropic, NMDA 2B0216
Glutamate receptor ionotropic, NMDA 2C0216
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0216
Glutamate receptor ionotropic, NMDA 3B0216
Glutamate receptor ionotropic, NMDA 3A0216
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Bile salt export pump0606
Bile salt export pump016016
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Chain A, Cruzipain4004
USP1 protein, partial7007
vitamin D3 receptor isoform VDRA6006
DNA polymerase kappa isoform 12002
caspase-1 isoform alpha precursor1001
Caspase-71001
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30709
Solute carrier organic anion transporter family member 1B10507
Carbonic anhydrase 40204
Carbonic anhydrase0103
Carbonic anhydrase 150204
TDP1 protein100010
EWS/FLI fusion protein4004
cytochrome P450 2C9 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Gamma-aminobutyric acid receptor subunit pi8109
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010010
Cytochrome P450 1A20202
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0203
DNA gyrase subunit A0306
DNA gyrase subunit B0306
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0203
Cytochrome P450 2D60101
DNA topoisomerase 2-alpha02112
Cytochrome P450 2C9 0303
Gamma-aminobutyric acid receptor subunit beta-18109
Gamma-aminobutyric acid receptor subunit delta8109
Gamma-aminobutyric acid receptor subunit gamma-28109
Gamma-aminobutyric acid receptor subunit alpha-58109
Gamma-aminobutyric acid receptor subunit alpha-38109
DNA gyrase subunit A0203
Gamma-aminobutyric acid receptor subunit gamma-18109
Gamma-aminobutyric acid receptor subunit alpha-28109
Gamma-aminobutyric acid receptor subunit alpha-48109
Gamma-aminobutyric acid receptor subunit gamma-38109
Gamma-aminobutyric acid receptor subunit alpha-68109
Cytochrome P450 2C190202
Multidrug resistance protein MdtK0011
Histamine H2 receptor4015
Gamma-aminobutyric acid receptor subunit alpha-18109
Gamma-aminobutyric acid receptor subunit beta-38109
Gamma-aminobutyric acid receptor subunit beta-28109
DNA gyrase subunit B0405
DNA gyrase subunit A0405
Enoyl-[acyl-carrier-protein] reductase [NADH]0207
Potassium voltage-gated channel subfamily H member 20507
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
GABA theta subunit8109
Canalicular multispecific organic anion transporter 1011012
Gamma-aminobutyric acid receptor subunit epsilon8109
importin subunit beta-1 isoform 12002
mitogen-activated protein kinase 16006
snurportin-12002
GTP-binding nuclear protein Ran isoform 12002
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
streptokinase A precursor0044
ATP-dependent translocase ABCB10607
Chain A, JmjC domain-containing histone demethylation protein 3A2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
G4004
cytochrome P450 2D62002
67.9K protein5005
cytochrome P450 2D6 isoform 12002
potassium voltage-gated channel subfamily H member 2 isoform d6006
transcriptional regulator ERG isoform 31001
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
eyes absent homolog 2 isoform a1001
peripheral myelin protein 223003
mitogen-activated protein kinase kinase kinase 3 isoform 10011
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Estrogen receptor0011
Spike glycoprotein0011
5-hydroxytryptamine receptor 1A0011
Cruzipain0101
C-terminal-binding protein 11001
Estrogen receptor beta0011
Inositol hexakisphosphate kinase 14004
Broad substrate specificity ATP-binding cassette transporter ABCG20202
cytochrome P450 2C9, partial4004
pregnane X receptor4004
GALC protein2002
Thrombopoietin1001
progesterone receptor4004
nonstructural protein 11001
retinoid X nuclear receptor alpha7007
farnesoid X nuclear receptor3003
pregnane X nuclear receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
thyroid stimulating hormone receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
thyroid hormone receptor beta isoform a2002
heat shock protein beta-13003
serine/threonine-protein kinase mTOR isoform 11001
survival motor neuron protein isoform d4004
cytochrome P450 3A4 isoform 18008
Solute carrier family 22 member 20102
Solute carrier family 22 member 1 0203
Solute carrier family 22 member 30203
Solute carrier family 22 member 30101
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0011
Androgen receptor0101
C-8 sterol isomerase0101
Solute carrier organic anion transporter family member 1A10202
Nuclear receptor ROR-gamma7007
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Solute carrier family 22 member 10304
Sigma non-opioid intracellular receptor 10101
Solute carrier family 22 member 20304
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
regulator of G-protein signaling 43003
peroxisome proliferator-activated receptor delta8008
M-phase phosphoprotein 81001
D-alanine--D-alanine ligase0101
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 0101
Chain A, Beta-lactamase3003
Motilin receptor0011
acid sphingomyelinase1001
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK12002
Motilin receptor0112
Rap guanine nucleotide exchange factor 32002
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
Albumin0022
ATP-dependent translocase ABCB10303
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
60 kDa heat shock protein, mitochondrial0202
Chitinase B0101
ATP-dependent translocase ABCB10303
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 2J20101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
10 kDa heat shock protein, mitochondrial0202
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0202
Lanosterol 14-alpha demethylase0202
50S ribosomal protein L36 20213
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Multidrug and toxin extrusion protein 10101
Pantothenate synthetase0202
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA polymerase beta2002
glp-1 receptor, partial2002
hypoxia-inducible factor 1 alpha subunit2002
SMAD family member 23003
SMAD family member 33003
caspase 7, apoptosis-related cysteine protease1001
nuclear receptor subfamily 1, group I, member 36006
peroxisome proliferator activated receptor gamma4004
caspase-31001
LMP1 [Human herpesvirus 4]0001
activating transcription factor 62002
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x2002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Voltage-dependent calcium channel gamma-2 subunit3003
Prothrombin0001
Regulatory protein E20011
Cellular tumor antigen p534004
DNA topoisomerase 10102
Polyunsaturated fatty acid lipoxygenase ALOX150202
DNA topoisomerase 20001
Glutamate receptor 23003
UDP-glucuronosyltransferase 1A1 0001
Serum paraoxonase/arylesterase 10101
Caspase-30101
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Tubulin beta-2B chain0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Chain E, Fibrin beta chain0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, RNA-directed RNA polymerase NS50101
Luciferase4004
15-lipoxygenase, partial4004
WRN1001
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
PPM1D protein2002
alkaline phosphatase, intestinal0011
apical membrane antigen 1, AMA12002
hypothetical protein, conserved1001
glucocerebrosidase1001
luciferase1001
bromodomain adjacent to zinc finger domain 2B3003
pyruvate kinase1001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
CDK50001
serine-protein kinase ATM isoform a1001
lysosomal alpha-glucosidase preproprotein1001
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
cellular tumor antigen p53 isoform a3003
glucose-6-phosphate 1-dehydrogenase isoform b0101
intestinal alkaline phosphatase precursor0011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
nuclear receptor ROR-gamma isoform 14004
Vif0101
Tat0101
histone acetyltransferase KAT2A isoform 14004
DNA dC->dU-editing enzyme APOBEC-3G isoform 11102
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Integrin beta-33003
Integrin alpha-IIb3003
Pyruvate kinase PKM0101
Endothelin receptor type B1001
Endothelin-1 receptor1001
phosphoglycerate kinase1001
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
large T antigen0101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
transforming acidic coiled-coil-containing protein 30001
Carbonic anhydrase 120002
Plasma kallikrein0002
Carbonic anhydrase 30002
Macrophage migration inhibitory factor0303
Carbonic anhydrase 60002
Histamine H2 receptor0123
Adenosine receptor A10002
Adenosine receptor A2a0002
Histamine H1 receptor0123
Histamine H1 receptor0213
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0002
Histamine H1 receptor0224
Carbonic anhydrase 70002
Carbonic anhydrase0003
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0202
Carbonic anhydrase 90002
Carbonic anhydrase 0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Carbonic anhydrase 0003
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130002
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 130002
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
Histamine H3 receptor0123
Chain A, HISTIDINE-BINDING PROTEIN0011
ATAD5 protein, partial2002
Histidine-binding periplasmic protein0011
Large neutral amino acids transporter small subunit 10303
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
aryl hydrocarbon receptor2002
N-glycosylase/DNA lyase0101
Myeloperoxidase0101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Endonuclease III-like protein 10101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0101
Endonuclease 8-like 10101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Phospholipase A-2-activating protein0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
DNA gyrase subunit B0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Potassium voltage-gated channel subfamily E member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
electroneutral potassium-chloride cotransporter KCC20011
estrogen receptor 2 (ER beta)5005
G-protein coupled receptor 550101
muscleblind-like protein 1 isoform 11001
Thymidylate synthase0101
Thymidylate synthase0101
Thymidylate synthase0101
Thymidylate synthase0101
Rap guanine nucleotide exchange factor 41001
Chain A, PROTEIN (CATECHOL OXIDASE)0101
interleukin 84004
Tyrosinase0101
Succinyl-diaminopimelate desuccinylase0101
Taste receptor type 2 member 380012
Glucocorticoid receptor0213
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
dopamine D1 receptor1001
NAD-dependent protein deacetylase sirtuin-60101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Alpha-synuclein0202
Disintegrin and metalloproteinase domain-containing protein 171001
Solute carrier organic anion transporter family member 1A40101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Protein-arginine deiminase type-40303
Chain A, Arginase 10101
nuclear receptor subfamily 1, group I, member 21001
twin arginine protein translocation system - TatA protein0001
TAR DNA-binding protein 431001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]