Hemangioendothelioma

A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)

Synonym
Hemangioendothelioma

Excerpt	Reference
"A case of primary hemangioendothelioma is presented."	( El-Mahdi, A; Langley, JR; Rosato, FE, 1978)
"The malignant hemangioendothelioma is observed nearly exclusively in some Alpine goiter areas."	( Hedinger, C, 1981)
"Hemangioendotheliomas are rare benign vascular tumors which may be grossly and histologically difficult to distinguish from highly malignant angiosarcomas."	( Acharya, G; Merritt, WH; Theogaraj, SD, 1980)
"Kaposiform hemangioendothelioma is a rare, aggressive vascular proliferation in children that is clinically and histologically distinct from hemangioma of infancy."	( Frieden, IJ; McCalmont, TH; Vin-Christian, K, 1997)
"Kaposiform hemangioendothelioma is a locally aggressive, endothelial-derived spindle cell neoplasm that occurs exclusively in infants and adolescents."	( Ball, NJ; Beaubien, ER; Storwick, GS, 1998)
"Spindle-cell hemangioendothelioma is a soft tissue skin tumor recently identified histologically."	( Amoric, JC; Benaceur, S; Bodemer, C; Brunelle, F; De Prost, Y; Fraitag, S, 1997)
"Spindle cell hemangioendothelioma is a vascular tumor recently described."	( Enjolras, O; Merland, JJ; Wassef, M, 1998)
"Infantile hemangioendothelioma is a severe disease with a high mortality."	( Choi, HY; Lee, SJ; Lee, SW; Park, EA; Seo, JW, 2001)
"Hepatic hemangioendothelioma is rare."	( Ko, SF; Kuo, HW; Liang, CD; Lu, CC; Tiao, MM, 2002)
"Infantile hemangioendothelioma is the most common hepatic vascular tumor in infants less than 6 months of age, with a prevalence of 1%."	( Akyüz, C; Büyükpamukçu, M; Haliloglu, M; Sari, N; Yalçin, B, 2006)
"Liver hemangioendotheliomas are capable of producing an excess of the thyroid hormone inactivating enzyme, type-3 iodothyronine deiodinase."	( Athanassaki, I; Balazs, AE; Gunn, SK; Haymond, MW; Huang, SA; Karaviti, LP; Tatevian, N, 2007)
"Hepatic hemangioendotheliomas are rare tumors in childhood."	( Ozkan, TB; Sevinir, B, 2007)
"Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal."	( Bradeen, HA; Kalof, AN; Lisle, JW, 2009)
"Hemangioendotheliomas are classified as endothelial cell tumors, which are the most common soft tissue tumors in infants."	( Fang, H; Gordillo, G; Park, H; Roy, S, 2010)
"Infantile hemangioendothelioma is a rare benign vascular tumor of the liver."	( Al-Tonbary, Y; Fouda, A, 2009)
"Kaposiform hemangioendothelioma is a rare vascular tumor in children."	( de Blaauw, I; Hermans, DJ; Kool, LJ; van Beynum, IM; van der Vijver, RJ; van der Vleuten, CJ, 2011)
"Hemangioendotheliomas are vascular neoplasms occupying a spectrum of biological potential ranging from benign to low-grade malignancy."	( Glass, LF; Jukic, DM; McNab, PM; Quigley, BC, 2013)
"Infantile hepatic hemangioendothelioma is the most common vascular tumor of the liver in infancy."	( Miranda, ME; Thomas Olivares, PA; Trujillo Gálvez, JJ; Villamil Martínez, R, 2013)
"Kaposiform hemangioendothelioma is a rare vascular neoplasm of childhood that may have an alarming and potentially misleading clinical presentation."	( Cyrulnik, AA; Dawkins, MC; Friedman, AJ; Jacobson, MI; Mann, RE; Smalberger, GJ; Young, S, 2014)
"Hemangioendotheliomas are categorized as intermediate-grade vascular tumors that are commonly localized in the lungs and livers."	( Madri, JA; Tsuneki, M, 2014)
"Kaposiform hemangioendothelioma is a rare locally aggressive vascular tumor associated with Kasabach Merritt syndrome."	( Abu-Leil, S; Bar-Oz, B; Diav-Citrin, O; Ergaz, Z; Simanovsky, N; Vainer, GW, 2014)
"Pseudomyogenic hemangioendothelioma is a rare soft tissue tumor usually found in young adults, predominantly males."	( Dai, M; Liu, H; Ye, C; Yu, X; Zeng, J, 2016)
"Pseudomyogenic hemangioendothelioma is a rare endothelial neoplasm which often mimics myoid and epithelioid tumors morphologically."	( Dai, M; Liu, H; Ye, C; Yu, X; Zeng, J, 2016)
"Hemangioendotheliomas are a heterogeneous group of vascular neoplasm that may affect the liver, bone, and soft tissues."	( Lambert, R; Mitchell, DA; Mourad, SA; Plouznikoff, N; Turcotte, RE; Turpin, S, 2020)
"Kaposiform hemangioendothelioma is an aggressive vascular tumor with infiltrative growth that commonly occurs in infancy and is associated with a life-threatening consumptive coagulopathy, as well as Kasabach-Merritt phenomenon."	( Cui, J; Kong, L; Shen, W; Sun, B; Wang, Y, 2020)
"Infantile hepatic hemangioendothelioma is a type of benign hepatic tumor that occurs in infancy."	( Guo, L; Li, J; Song, D; Wang, L; Wu, C; Yin, J, 2020)
"Kaposiform hemangioendothelioma is a rare vascular tumor with borderline malignancy and is typically diagnosed in infancy or early childhood."	( Duan, J; Song, L; Xu, H, 2022)
"Composite hemangioendothelioma is a rare disease that exhibits biological potency ranging from benign to low-grade malignancy, and hepatic and bone metastases are even rarer."	( Huang, W; Kang, L; Li, L; Yang, Q; Zhou, Y, 2023)

Excerpt	Reference
"The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas)."	( Carrillo, R; Fernández-Herrera, J; Kutzner, H; Luis Díaz, J; Manzarbeitia, F; Requena, L, 2008)

Excerpt	Reference
"Rapamycin has been recommended to treat Kaposiform hemangioendothelioma (KHE) with Kasabach-Merritt phenomenon (KMP), but the underlying mechanism of the clinical effect has not been established."	( Han, Q; Li, K; Wang, J; Wang, L; Wang, Z; Yao, W, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	251 (47.54)	23.3326
1990's	66 (12.50)	12.5806
2000's	56 (10.61)	18.1394
2010's	111 (21.02)	28.8240
2020's	44 (8.33)	9.53

Drug	Relationship Strength	Studies	Trials
choline	low	1	0
hydrochloric acid	low	1	0
salicylic acid	low	38	0
cytosine	low	1	0
iodine	low	3	0
methanol	low	1	0
phytic acid	low	1	0
nickel	low	1	0
nitrites	low	3	0
thiosulfates	low	1	0
toluene	low	2	0
vanilmandelic acid	low	1	0
1,2-dimethylhydrazine	low	4	0
3-methylcholanthrene	low	3	0
homovanillic acid	low	1	0
acetaminophen	low	1	0
albuterol	low	1	0
aspirin	low	4	0
atenolol	low	2	0
azathioprine	low	2	0
celecoxib	low	1	0
chloral hydrate	low	1	0
deferiprone	low	1	0
deferoxamine	low	1	0
ddt	low	1	0
pentetic acid	low	2	0
fluorouracil	low	2	0
furosemide	low	1	0
halothane	low	2	0
hexestrol	low	1	0
ifosfamide	low	1	0
isoniazid	low	2	0
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1	0
methoxyflurane	low	2	0
nafamostat	low	1	0
pamidronate	low	1	0
pentobarbital	low	1	0
pentoxifylline	low	2	0
phenobarbital	low	1	0
pioglitazone	medium	1	1
propranolol	low	22	0
rofecoxib	medium	1	1
thalidomide	low	3	0
ticlopidine	low	2	0
urethane	low	4	0
prednisolone	medium	26	1
thyroxine	low	9	0
prednisone	low	22	0
triiodothyronine	low	2	0
diethylnitrosamine	low	4	0
benz(a)anthracene	low	1	0
lysine	low	1	0
aminopyrine	low	2	0
galactose	low	1	0
carbostyril	low	1	0
p-dimethylaminoazobenzene	low	1	0
tyrosine	low	2	0
dimethylnitrosamine	low	4	0
methionine	low	1	0
phenylalanine	low	1	0
norethynodrel	low	1	0
cytarabine	low	1	0
histidine	low	1	0
mestranol	low	1	0
tryptophan	low	1	0
vinyl chloride	low	8	0
triamcinolone acetonide	low	2	0
fluoxymesterone	low	1	0
phencyclidine	low	1	0
methylprednisolone	low	9	0
quinoline	low	1	0
o-aminoazotoluene	low	2	0
n-nitrosopiperidine	low	1	0
pyrroles	low	1	0
thiophenes	low	2	0
oxyphenisatin acetate	low	1	0
diatrizoate meglumine	low	1	0
meglumine	low	1	0
captan	low	1	0
iodohippuric acid	low	1	0
indazoles	low	1	0
hydrazine	low	1	0
betamethasone	low	1	0
reticulin	low	2	0
propylnitrosourea	low	1	0
thorium dioxide	low	50	0
methylprednisolone hemisuccinate	low	1	0
captafol	low	1	0
sulfur hexafluoride	low	1	0
streptomycin	low	1	0
chlorphenamidine	low	1	0
iridium	low	1	0
silver	low	1	0
technetium	low	13	0
thorium	low	4	0
gadolinium	low	5	0
barium sulfate	low	1	0
copper sulfate	low	1	0
deuterium	low	1	0
thallium chloride	low	1	0
razoxane	low	1	0
phenyl acetate	low	1	0
triamcinolone	low	2	0
timolol	low	1	0
paclitaxel	low	2	0
diethylmethylnitrosourea	low	1	0
diisopropanolnitrosamine	low	1	0
propiconazole	low	7	0
nitrosobis(2-oxopropyl)amine	low	1	0
2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole	low	1	0
itraconazole	low	1	0
salmeterol xinafoate	low	1	0
imiquimod	low	2	0
cidofovir anhydrous	low	1	0
dimethylhydrazines	low	4	0
trofosfamide	medium	1	1
2-methoxyestradiol	low	1	0
fluorodeoxyglucose f18	low	8	0
zoledronic acid	low	1	0
n-(3,5-dichlorophenyl)succinimide	low	1	0
fibrinogen	low	1	0
yttrium radioisotopes	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
imatinib mesylate	low	1	0
methotrexate	low	9	0
proline	low	1	0
docetaxel anhydrous	low	1	0
organophosphonates	low	1	0
aflatoxin b1	low	1	0
lenalidomide	low	2	0
cortisone	low	2	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
o-(chloroacetylcarbamoyl)fumagillol	low	2	0
carboplatin	low	1	0
glycogen	low	1	0
inositol 3-phosphate	low	1	0
tacrolimus	medium	2	1
zithromax	low	1	0
diethylstilbestrol	low	1	0
dactinomycin	low	3	0
bromochloroacetic acid	low	5	0
dimethyl fumarate	low	1	0
glycosides	low	1	0
isomethyleugenol	low	1	0
stilbenes	low	2	0
picibanil	low	1	0
pyrophosphate	low	1	0
propylthiouracil	low	2	0
sesquiterpenes	low	3	0
mercaptopurine	low	2	0
curcumin	low	1	0
digoxin	low	2	0
tamoxifen	low	1	0
naphthoquinones	low	1	0
bilirubin	low	4	0
petasitenine	low	1	0
senkirkine	low	1	0
ethamolin	low	1	0
phenylephrine hydrochloride	low	1	0
fluticasone	low	1	0
su 11248	low	1	0
fosbretabulin	low	1	0
lead	low	1	0
thallium	low	1	0
arsenic	low	3	0
batimastat	low	1	0
sulfur	low	1	0
methylazoxymethanol acetate	low	1	0
radium	low	4	0
everolimus	low	6	0
gadolinium dtpa	low	4	0
oxi 4503	low	1	0
pazopanib	low	1	0
sepantronium	low	1	0
oxadiazoles	low	1	0
pirarubicin	low	1	0
pf 573228	low	1	0
indocyanine green	low	1	0
bleomycetin	low	1	0
c-peptide	low	1	0
gsk690693	low	1	0
calpain	low	1	0
sodium pertechnetate tc 99m	low	1	0
sodium ethylxanthate	low	1	0
piperidines	low	2	0
interleukin-8	low	1	0
vasoactive intestinal peptide	low	1	0
heparitin sulfate	low	1	0
ascorbic acid	low	3	0
oxytetracycline, anhydrous	low	2	0
warfarin	low	2	0
phenprocoumon	low	1	0
epidermal growth factor	low	1	0
cyclin d1	low	2	0
technetium tc 99m sulfur colloid	low	3	0
technetium tc 99m medronate	low	5	0
cord factors	low	1	0
lewis y antigen	low	1	0
lutetium lu 177 dotatate	low	1	0
angiogenin	low	1	0
deoxyguanosine	low	1	0
folic acid	low	1	0
dacarbazine	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
eye	low	1	0

Protein Targets (1,688)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
Chain A, Cruzipain	11	0	0	11
regulator of G-protein signaling 4	16	0	0	16
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	7	0	0	7
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	18	0	0	18
Chain B, HADH2 protein	18	0	0	18
Chain A, 2-oxoglutarate Oxygenase	19	0	0	19
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	26	0	0	26
15-lipoxygenase, partial	11	0	0	11
ATAD5 protein, partial	18	0	0	18
NFKB1 protein, partial	7	0	0	7
TDP1 protein	49	0	0	49
Thrombopoietin	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	36	0	0	36
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
thyroid stimulating hormone receptor	24	0	0	24
EWS/FLI fusion protein	32	0	0	33
67.9K protein	18	0	0	18
Parkin	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	43	0	0	43
cytochrome P450 2D6 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C19 precursor	6	0	0	6
cytochrome P450 2C9 precursor	3	0	0	3
chromobox protein homolog 1	33	0	0	33
flap endonuclease 1	12	0	0	12
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
survival motor neuron protein isoform d	16	0	0	16
cytochrome P450 3A4 isoform 1	21	0	0	21
M-phase phosphoprotein 8	8	0	0	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	3	6
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	2	5	7
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	3	4
Gamma-aminobutyric acid receptor subunit pi	21	1	4	26
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
Bromodomain-containing protein 4	0	2	0	2
5-hydroxytryptamine receptor 4	0	8	0	8
cGMP-specific 3',5'-cyclic phosphodiesterase	0	4	0	4
Integrin beta-3	8	3	0	11
Cytochrome P450 1A2	0	4	0	5
Integrin alpha-IIb	8	2	0	10
Neuronal acetylcholine receptor subunit alpha-4	3	3	0	6
Serine/threonine-protein kinase pim-1	0	1	5	6
Neuronal acetylcholine receptor subunit beta-2	3	3	0	6
Gamma-aminobutyric acid receptor subunit beta-1	21	1	4	26
Gamma-aminobutyric acid receptor subunit delta	21	1	4	26
Gamma-aminobutyric acid receptor subunit gamma-2	21	1	4	26
Casein kinase II subunit alpha'	0	1	5	6
Gamma-aminobutyric acid receptor subunit alpha-5	21	1	4	26
Gamma-aminobutyric acid receptor subunit alpha-3	21	1	4	26
Gamma-aminobutyric acid receptor subunit gamma-1	21	1	4	26
Gamma-aminobutyric acid receptor subunit alpha-2	21	1	4	26
Proteinase-activated receptor 1	0	0	0	1
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	2
5-hydroxytryptamine receptor 2A	0	8	1	9
5-hydroxytryptamine receptor 2C	0	8	1	9
Gamma-aminobutyric acid receptor subunit alpha-4	21	1	4	26
Gamma-aminobutyric acid receptor subunit gamma-3	21	1	4	26
Gamma-aminobutyric acid receptor subunit alpha-6	21	1	4	26
Sodium-dependent serotonin transporter	0	3	1	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	8	1	9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	3	3	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	3	7
Serine/threonine-protein kinase mTOR	0	5	5	10
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	10	0	0	10
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	3	6
Glycogen synthase kinase-3 beta	0	4	5	9
D(1A) dopamine receptor	4	0	0	4
Serine/threonine-protein kinase PLK1	0	4	5	9
Gamma-aminobutyric acid receptor subunit alpha-1	21	4	4	29
Gamma-aminobutyric acid receptor subunit beta-3	21	1	4	26
Gamma-aminobutyric acid receptor subunit beta-2	21	1	4	26
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	3	4
DNA-dependent protein kinase catalytic subunit	0	3	0	3
Mu-type opioid receptor	0	5	0	5
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
Serine/threonine-protein kinase ATR	0	1	1	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	3	4
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	21	1	4	26
Gamma-aminobutyric acid receptor subunit epsilon	21	1	4	26
Serine/threonine-protein kinase PLK3	0	3	3	6
Serine/threonine-protein kinase PLK2	0	2	3	5
ATP-dependent phosphofructokinase	16	0	0	16
Chain A, Beta-lactamase	13	0	0	13
glp-1 receptor, partial	17	0	0	17
GLS protein	17	0	0	17
PPM1D protein	13	0	0	13
estrogen-related nuclear receptor alpha	57	0	0	57
glucocerebrosidase	6	0	0	6
IDH1	27	0	0	27
lysosomal alpha-glucosidase preproprotein	7	0	0	7
interferon gamma precursor	0	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	18
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	49	0	0	49
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
lamin isoform A-delta10	44	0	0	44
Interferon beta	31	0	0	31
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Sex hormone-binding globulin	0	0	2	2
Cytochrome P450 1A1	0	1	1	3
TAR DNA-binding protein 43	11	0	0	11
Cytochrome P450 1B1	0	1	0	1
Tubulin beta-2B chain	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
Luciferase	25	0	0	25
pregnane X receptor	16	0	0	16
phosphopantetheinyl transferase	17	0	0	17
RAR-related orphan receptor gamma	48	0	0	48
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
Microtubule-associated protein tau	16	0	0	16
AR protein	64	0	0	64
caspase 7, apoptosis-related cysteine protease	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	37	0	0	37
retinoic acid nuclear receptor alpha variant 1	49	0	0	49
farnesoid X nuclear receptor	28	0	0	28
pregnane X nuclear receptor	48	0	0	48
estrogen nuclear receptor alpha	76	0	0	76
peroxisome proliferator-activated receptor delta	33	0	0	33
peroxisome proliferator activated receptor gamma	40	0	0	40
caspase-3	10	0	0	10
aryl hydrocarbon receptor	29	0	0	29
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
activating transcription factor 6	24	0	0	24
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	21	0	0	21
thyroid hormone receptor beta isoform a	23	0	0	23
heat shock protein beta-1	21	0	0	21
nuclear factor erythroid 2-related factor 2 isoform 1	51	0	0	51
Voltage-dependent calcium channel gamma-2 subunit	31	0	0	31
Cellular tumor antigen p53	45	0	0	45
Tyrosine-protein kinase Lck	0	3	5	8
Tyrosine-protein kinase Fyn	0	4	5	9
Aldo-keto reductase family 1 member B1	0	10	0	10
Adenosine receptor A3	0	9	1	10
Alpha-1B adrenergic receptor	0	10	1	11
Glutamate receptor 2	31	0	0	31
Acetylcholinesterase	0	10	0	10
Sodium-dependent noradrenaline transporter	0	10	0	10
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	10	1	11
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Smad3	12	0	0	12
progesterone receptor	37	0	0	37
retinoid X nuclear receptor alpha	40	0	0	40
thyroid hormone receptor beta isoform 2	47	0	0	47
peripheral myelin protein 22	27	0	0	27
ATP-binding cassette sub-family C member 3	0	36	0	36
Multidrug resistance-associated protein 4	0	36	0	38
Solute carrier family 22 member 6	0	4	0	5
Carbonic anhydrase 12	0	6	0	11
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	10	0	10
Bile salt export pump	0	50	0	50
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	14	0	20
Carbonic anhydrase 2	0	15	1	22
Myoglobin	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 3	0	5	0	9
Cytochrome P450 3A4	0	11	0	12
Cytochrome P450 2D6	0	7	0	7
Cytochrome P450 2C9	0	9	0	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Sulfotransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Carbonic anhydrase 4	0	7	0	12
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 6	0	6	0	11
Carbonic anhydrase 5A, mitochondrial	0	6	0	11
Prostaglandin G/H synthase 2	0	8	4	14
Carbonic anhydrase 7	0	6	0	11
Nuclear receptor ROR-gamma	16	1	1	18
Cytochrome P450 2J2	0	6	0	6
Carbonic anhydrase 9	0	9	0	14
Canalicular multispecific organic anion transporter 1	0	35	0	35
Carbonic anhydrase 15	0	4	0	8
Carbonic anhydrase 13	0	4	0	8
Carbonic anhydrase 14	0	6	0	11
Carbonic anhydrase 5B, mitochondrial	0	6	0	11
toxin B	0	0	0	1
Acetylcholinesterase	0	1	0	1
NPYLR7B	0	0	2	2
arylsulfatase A	13	0	0	13
thyroid stimulating hormone receptor	26	0	0	26
Beta-2 adrenergic receptor	0	8	4	12
Beta-1 adrenergic receptor	0	10	4	14
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-3 adrenergic receptor	0	8	3	11
Delta-type opioid receptor	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
Beta-2 adrenergic receptor	0	0	1	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Beta-2 adrenergic receptor	0	2	5	8
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	15	0	0	15
Chain A, Apolipoprotein	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	33	0	0	33
nonstructural protein 1	8	0	0	8
glucocorticoid receptor [Homo sapiens]	52	0	0	52
D(1A) dopamine receptor	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Rap guanine nucleotide exchange factor 3	4	0	0	4
Plasminogen	0	4	1	5
Proton-coupled amino acid transporter 1	0	2	0	2
interleukin 8	13	0	0	13
GLI family zinc finger 3	49	0	0	49
estrogen receptor 2 (ER beta)	27	0	0	27
G	19	0	0	19
vitamin D (1,25- dihydroxyvitamin D3) receptor	36	0	0	36
v-jun sarcoma virus 17 oncogene homolog (avian)	28	0	0	28
histone deacetylase 9 isoform 3	8	0	0	8
HLA class I histocompatibility antigen, B alpha chain	19	0	0	19
Nicotinate phosphoribosyltransferase	0	3	0	3
Inositol hexakisphosphate kinase 1	19	0	0	19
cytochrome P450 2C9, partial	19	0	0	19
ORF73	0	0	3	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	18	0	0	18
thioredoxin glutathione reductase	10	0	0	10
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	13	0	0	13
Polyphenol oxidase 2	0	3	0	5
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	8	2	11
Spike glycoprotein	20	0	1	21
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	19	0	0	19
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	2	0	0	2
cytochrome P450 2D6	17	0	0	17
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Bloom syndrome protein isoform 1	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
DNA polymerase iota isoform a (long)	15	0	0	15
DNA polymerase kappa isoform 1	12	0	0	12
muscarinic acetylcholine receptor M1	9	0	0	9
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Epidermal growth factor receptor	0	5	5	10
Fatty acid-binding protein, liver	0	3	0	3
Myeloperoxidase	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	3	0	3
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	2	0	5
Adenosine receptor A2a	0	1	0	4
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	5	0	5
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	2	1	3
Beta-1 adrenergic receptor	0	1	3	5
5-hydroxytryptamine receptor 1A	0	8	3	12
Alpha-1D adrenergic receptor	0	7	1	9
Alpha-1A adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	1	1	3
Fumarate hydratase	12	0	0	12
polyprotein	12	0	0	12
P53	1	0	0	1
Histone H2A.x	20	0	0	20
peripheral myelin protein 22 isoform 1	9	0	0	9
hemoglobin subunit beta	4	0	0	4
muscleblind-like protein 1 isoform 1	9	0	0	9
ATPase family AAA domain-containing protein 5	29	0	0	29
Ataxin-2	32	0	0	32
Protein-arginine deiminase type-4	0	5	0	5
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Interstitial collagenase	0	2	0	2
Low affinity immunoglobulin epsilon Fc receptor	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	2	1	3
Matrilysin	0	1	0	1
Matrix metalloproteinase-9	0	4	0	4
Neutrophil collagenase	0	3	0	3
Metabotropic glutamate receptor 5	0	1	0	1
Collagenase 3	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Matrix metalloproteinase-14	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	4	1	0	5
Snake venom metalloproteinase BaP1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
galanin receptor type 3	0	2	0	2
Glucocorticoid receptor	0	16	2	23
Glycine receptor subunit alpha-1	0	16	0	16
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
Chain A, Putative fructose-1,6-bisphosphate aldolase	13	0	0	13
USP1 protein, partial	22	0	0	22
vitamin D3 receptor isoform VDRA	16	0	0	16
caspase-1 isoform alpha precursor	5	0	0	5
Caspase-7	5	0	0	5
Solute carrier organic anion transporter family member 1B3	0	5	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	10
hypoxia-inducible factor 1 alpha subunit	21	0	0	21
thyrotropin-releasing hormone receptor	7	0	0	7
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Replicase polyprotein 1ab	0	2	1	3
potassium voltage-gated channel subfamily H member 2 isoform d	11	0	0	11
huntingtin isoform 2	5	0	0	5
mitogen-activated protein kinase 1	7	0	0	7
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
nuclear receptor ROR-gamma isoform 1	17	0	0	17
Replicase polyprotein 1ab	0	5	2	7
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	2	0	2
Carbonic anhydrase 13	0	2	0	4
Poly [ADP-ribose] polymerase tankyrase-2	0	1	1	2
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
prostaglandin E2 receptor EP2 subtype	0	0	0	1
Prostaglandin E synthase	0	2	0	2
Histone deacetylase 3	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	3	4
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Procathepsin L	0	1	1	2
Polyunsaturated fatty acid 5-lipoxygenase	0	5	0	5
Quinolone resistance protein NorA	0	1	0	1
Calpain-2 catalytic subunit	0	2	0	2
D(1A) dopamine receptor	0	7	1	8
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sodium-dependent serotonin transporter	0	10	0	10
Delta-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	2	0	2
Bifunctional epoxide hydrolase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Carbonic anhydrase	0	4	0	8
Carbonic anhydrase	0	1	0	5
Histone deacetylase 4	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	6	0	6
Prostaglandin G/H synthase 2	0	2	0	2
Histone deacetylase 1	0	3	0	3
Mitogen-activated protein kinase 14	0	2	5	7
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase	0	1	0	5
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	2	0	2
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	3	0	3
Carbonic anhydrase 4	0	2	0	3
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	3	0	3
P2Y purinoceptor 12	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Thymidine kinase	0	1	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	1
Solute carrier family 22 member 6	0	2	0	4
endonuclease IV	5	0	0	5
dopamine D1 receptor	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Nrf2	1	0	0	1
alkaline phosphatase, intestinal	0	1	0	1
apical membrane antigen 1, AMA1	10	0	0	10
PINK1	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	6	0	0	6
importin subunit beta-1 isoform 1	5	0	0	5
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	5	0	0	5
snurportin-1	5	0	0	5
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
neuropeptide S receptor isoform A	5	0	0	5
Acetylcholinesterase	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Amyloid-beta precursor protein	1	1	0	3
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cholinesterase	0	2	0	2
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Replicase polyprotein 1ab	0	2	2	4
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	2	1	3
Amine oxidase [flavin-containing] B	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	7	1	1	9
Beta-secretase 1	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Cholinesterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	3	4
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	2	1	3
Nuclear factor erythroid 2-related factor 2	0	0	2	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	6	0	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	8
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	3
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	4	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	5	7
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Isocitrate lyase	0	2	0	2
RAD51	0	1	0	1
ATP-dependent translocase ABCB1	0	8	1	13
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Discoidin domain-containing receptor 2	0	2	5	7
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Androgen receptor	0	10	0	10
Lysine-specific demethylase 6A	0	1	0	1
Lysine-specific demethylase 4A	0	2	0	2
Lysine-specific demethylase 5C	0	1	0	1
Lysine-specific demethylase 2B	0	1	0	1
Deoxyhypusine hydroxylase	0	2	0	2
Lysine-specific demethylase 2A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Hsf1 protein	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
serine/threonine-protein kinase PLK1	5	0	0	5
high affinity choline transporter 1 isoform a	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	4	5
Estrogen receptor	0	8	2	11
Alpha-2A adrenergic receptor	0	7	2	10
Muscarinic acetylcholine receptor M1	0	5	1	6
D(2) dopamine receptor	0	5	1	6
Alpha-2C adrenergic receptor	0	5	2	8
Muscarinic acetylcholine receptor M3	0	5	1	6
Substance-K receptor	0	6	0	6
Thromboxane-A synthase	0	2	0	2
Adenosine receptor A2a	0	7	1	8
Adenosine receptor A1	0	6	0	6
Mu-type opioid receptor	0	5	1	6
D(3) dopamine receptor	0	4	0	4
Vasopressin V1a receptor	0	3	1	4
Delta-type opioid receptor	0	7	1	8
Kappa-type opioid receptor	0	5	1	6
5-hydroxytryptamine receptor 6	0	6	1	7
Estrogen-related receptor gamma	0	1	1	2
Aldehyde oxidase	0	1	0	1
UDP-glucose 4-epimerase	0	1	0	1
Estrogen receptor beta	0	6	2	8
Cysteinyl leukotriene receptor 1	0	2	0	2
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
alpha-galactosidase	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
ras-related protein Rab-9A	3	0	0	3
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	5
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	3
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Kelch-like ECH-associated protein 1	0	0	1	1
acid sphingomyelinase	3	0	0	3
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
LANA	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
eyes absent homolog 2 isoform a	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
kelch-like ECH-associated protein 1	0	0	0	2
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Serum paraoxonase/arylesterase 1	0	5	0	5
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
Bone morphogenetic protein receptor type-1B	0	0	5	5
Cell division cycle 7-related protein kinase	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	5	5
Pyridoxal kinase	0	0	5	5
Citron Rho-interacting kinase	0	0	5	5
Serine/threonine-protein kinase Chk1	0	1	5	6
Aurora kinase A	0	1	5	6
Cyclin-G-associated kinase	0	0	5	5
Ephrin type-B receptor 6	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 3	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 2	0	0	5	5
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	5	5
Dynamin-like 120 kDa protein, mitochondrial	0	0	5	5
Eukaryotic translation initiation factor 5B	0	0	3	3
Rho-associated protein kinase 2	0	0	5	5
Serine/threonine-protein kinase ULK1	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	5	5
Ribosomal protein S6 kinase alpha-5	0	1	5	6
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	5	5
Ribosomal protein S6 kinase alpha-4	0	0	5	5
Serine/threonine-protein kinase 16	0	0	5	5
Serine/threonine-protein kinase 10	0	0	5	5
Serine/threonine-protein kinase D3	0	1	5	6
Structural maintenance of chromosomes protein 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 6	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	5	5
Serine/threonine-protein kinase LATS1	0	0	5	5
Serine/threonine-protein kinase PAK 4	0	3	5	8
Tyrosine-protein kinase ABL1	0	4	8	13
High affinity nerve growth factor receptor	0	0	5	5
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	3	3
ADP/ATP translocase 2	0	0	5	5
Protein kinase C beta type	0	2	5	7
Insulin receptor	0	1	5	6
Cyclin-dependent kinase 1	0	2	5	7
Glycogen phosphorylase, liver form	0	0	5	5
Tyrosine-protein kinase Fes/Fps	0	0	5	5
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	0	5	5
Tyrosine-protein kinase Lyn	0	0	5	5
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	5	6
Insulin-like growth factor 1 receptor	0	0	5	5
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	5	5
Hepatocyte growth factor receptor	0	1	5	6
Tyrosine-protein kinase HCK	0	1	5	6
Platelet-derived growth factor receptor beta	0	4	5	9
Tyrosine-protein kinase Fgr	0	0	5	5
Serine/threonine-protein kinase A-Raf	0	0	5	5
Glycogen phosphorylase, brain form	0	0	5	5
Breakpoint cluster region protein	0	0	7	8
Fibroblast growth factor receptor 1	0	3	5	8
DNA topoisomerase 2-alpha	0	0	5	5
Cyclin-dependent kinase 4	0	0	5	5
ADP/ATP translocase 3	0	0	5	5
Inosine-5'-monophosphate dehydrogenase 2	0	0	5	5
Proto-oncogene tyrosine-protein kinase Src	0	2	5	7
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	5	5
Serine/threonine-protein kinase B-raf	0	0	5	5
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	5	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	5	5
Tyrosine-protein kinase Fer	0	0	5	5
Protein kinase C alpha type	0	1	5	6
cAMP-dependent protein kinase catalytic subunit alpha	0	0	5	5
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	5	5
Ras-related protein Rab-6A	0	0	4	4
Ephrin type-A receptor 1	0	0	5	5
Multifunctional protein ADE2	0	0	5	5
cAMP-dependent protein kinase catalytic subunit gamma	0	0	4	4
cAMP-dependent protein kinase catalytic subunit beta	0	0	5	5
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	5	5
Tyrosine-protein kinase JAK1	0	0	5	5
Cyclin-dependent kinase 2	0	2	6	8
Beta-adrenergic receptor kinase 1	0	0	5	5
Probable ATP-dependent RNA helicase DDX6	0	0	5	5
Mitogen-activated protein kinase 3	0	0	5	5
MAP/microtubule affinity-regulating kinase 3	0	0	5	5
Mitogen-activated protein kinase 1	0	0	5	5
Ephrin type-A receptor 2	0	0	5	5
Ephrin type-B receptor 2	0	0	5	5
Non-receptor tyrosine-protein kinase TYK2	0	0	5	5
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	5	5
Heme oxygenase 2	0	0	5	5
S-adenosylmethionine synthase isoform type-2	0	0	5	5
DnaJ homolog subfamily A member 1	0	0	5	5
RAC-alpha serine/threonine-protein kinase	0	4	5	9
RAC-beta serine/threonine-protein kinase	0	2	5	7
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	5	5
Myosin-10	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 2	0	0	5	5
Receptor-type tyrosine-protein kinase FLT3	0	1	5	7
Bone morphogenetic protein receptor type-1A	0	0	5	5
Activin receptor type-1B	0	0	5	5
TGF-beta receptor type-1	0	0	5	5
TGF-beta receptor type-2	0	0	5	5
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	0	5	5
Glycine--tRNA ligase	0	0	5	5
Protein kinase C iota type	0	1	5	6
Exosome RNA helicase MTR4	0	0	5	5
Tyrosine-protein kinase Tec	0	0	5	5
Tyrosine-protein kinase ABL2	0	0	5	5
Tyrosine-protein kinase FRK	0	0	5	5
G protein-coupled receptor kinase 6	0	0	4	4
Tyrosine-protein kinase SYK	0	0	5	5
26S proteasome regulatory subunit 6B	0	0	5	5
Mitogen-activated protein kinase 8	0	0	5	5
Mitogen-activated protein kinase 9	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 3	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	4	4
Casein kinase I isoform alpha	0	1	5	6
Casein kinase I isoform delta	0	0	5	5
MAP kinase-activated protein kinase 2	0	0	5	5
Elongation factor Tu, mitochondrial	0	0	5	5
Choline-phosphate cytidylyltransferase A	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	5	5
Casein kinase I isoform epsilon	0	0	5	5
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	5	5
Dual specificity protein kinase CLK1	0	0	5	5
Dual specificity protein kinase CLK2	0	0	5	5
Dual specificity protein kinase CLK3	0	0	5	5
Glycogen synthase kinase-3 alpha	0	0	5	5
Cyclin-dependent kinase 7	0	1	5	6
Cyclin-dependent kinase 9	0	0	5	5
Ras-related protein Rab-27A	0	0	5	5
Interleukin-1 receptor-associated kinase 1	0	0	5	5
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Ribosomal protein S6 kinase alpha-3	0	1	5	6
Serine/threonine-protein kinase Nek2	0	1	5	6
Serine/threonine-protein kinase Nek3	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 6	0	0	5	5
LIM domain kinase 1	0	0	5	5
LIM domain kinase 2	0	0	5	5
Mitogen-activated protein kinase 10	0	0	5	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-1	0	0	5	6
Ephrin type-B receptor 3	0	0	5	5
Ephrin type-A receptor 5	0	0	5	5
Ephrin type-B receptor 4	0	1	5	6
Ephrin type-A receptor 4	0	0	5	5
Adenylate kinase 2, mitochondrial	0	0	5	5
Adenosine kinase	0	0	5	5
Ras-related protein Rab-10	0	0	5	5
Actin-related protein 3	0	0	5	5
Actin-related protein 2	0	0	5	5
GTP-binding nuclear protein Ran	0	0	5	5
Casein kinase I isoform gamma-2	0	0	5	5
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase 6	0	0	5	5
Cyclin-dependent-like kinase 5	0	0	5	5
Cyclin-dependent kinase 16	0	0	5	5
Cyclin-dependent kinase 17	0	0	5	5
ATP-dependent 6-phosphofructokinase, platelet type	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 1	0	0	5	5
DNA topoisomerase 2-beta	0	0	5	5
Protein kinase C theta type	0	2	5	7
Activin receptor type-1	0	0	5	5
Macrophage-stimulating protein receptor	0	0	5	5
Focal adhesion kinase 1	0	2	5	7
Protein kinase C delta type	0	2	5	7
Tyrosine-protein kinase BTK	0	0	5	5
Activated CDC42 kinase 1	0	0	5	5
Epithelial discoidin domain-containing receptor 1	0	0	5	5
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	5	5
Serine/threonine-protein kinase 4	0	0	5	5
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	5	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase 7	0	0	5	5
Serine/threonine-protein kinase PAK 2	0	0	5	5
Serine/threonine-protein kinase 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 1	0	0	5	5
Integrin-linked protein kinase	0	0	5	5
Rho-associated protein kinase 1	0	1	5	6
Non-receptor tyrosine-protein kinase TNK1	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	5	5
Activin receptor type-2B	0	0	5	5
Bone morphogenetic protein receptor type-2	0	0	5	5
Protein-tyrosine kinase 6	0	0	5	5
cGMP-dependent protein kinase 1	0	1	5	6
Cyclin-dependent kinase 13	0	0	5	5
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	5	5
Protein-tyrosine kinase 2-beta	0	1	5	6
Sodium channel protein type 5 subunit alpha	0	3	0	3
Maternal embryonic leucine zipper kinase	0	0	5	5
Structural maintenance of chromosomes protein 1A	0	0	5	5
Chromodomain-helicase-DNA-binding protein 4	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 1	0	0	5	5
Ephrin type-A receptor 7	0	0	4	4
Delta(24)-sterol reductase	0	0	5	5
Ribosomal protein S6 kinase alpha-1	0	2	5	7
Dual specificity testis-specific protein kinase 1	0	0	5	5
Myosin light chain kinase, smooth muscle	0	0	5	5
Mitogen-activated protein kinase 11	0	0	5	5
Serine/threonine-protein kinase STK11	0	0	5	5
Serine/threonine-protein kinase N1	0	0	5	5
Serine/threonine-protein kinase N2	0	0	5	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	5	5
Mitogen-activated protein kinase kinase kinase 11	0	0	5	5
AP2-associated protein kinase 1	0	1	5	6
Myosin light chain kinase 3	0	0	5	5
Putative heat shock protein HSP 90-beta 2	0	0	5	5
Serine/threonine-protein kinase MRCK alpha	0	0	5	5
Serine/threonine-protein kinase MRCK gamma	0	0	5	5
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	5	5
Uncharacterized protein FLJ45252	0	0	5	5
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	5	5
Serine/threonine-protein kinase MARK2	0	0	5	5
ATP-dependent RNA helicase DHX30	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	5	5
STE20-related kinase adapter protein alpha	0	0	5	5
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	5	5
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	5	5
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	5	5
Mitogen-activated protein kinase 15	0	0	5	5
Serine/threonine-protein kinase Nek9	0	0	5	5
Serine/threonine-protein kinase Nek7	0	0	4	4
ATP-dependent RNA helicase DDX1	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	5	5
Aurora kinase B	0	1	5	6
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Serine/threonine-protein kinase Nek1	0	0	5	5
PAS domain-containing serine/threonine-protein kinase	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	5	5
EKC/KEOPS complex subunit TP53RK	0	0	5	5
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase kinase kinase 3	0	0	5	5
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	5	5
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	5	5
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	5	5
Serine/threonine-protein kinase SIK2	0	0	5	5
STE20-like serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO3	0	0	5	5
dCTP pyrophosphatase 1	0	0	5	5
Dual specificity protein kinase CLK4	0	0	5	5
Casein kinase I isoform gamma-1	0	0	5	5
Phenylalanine--tRNA ligase beta subunit	0	0	5	5
BMP-2-inducible protein kinase	0	0	5	5
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	5	5
Interleukin-1 receptor-associated kinase 4	0	0	5	5
Mitogen-activated protein kinase kinase kinase 20	0	0	5	5
Cyclin-dependent kinase 12	0	0	5	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase 26	0	0	5	5
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-2	0	0	5	6
Serine/threonine-protein kinase TBK1	0	1	5	6
Septin-9	0	0	5	5
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Ribosomal protein S6 kinase alpha-6	0	0	5	5
TRAF2 and NCK-interacting protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO2	0	0	5	5
Long-chain-fatty-acid--CoA ligase 5	0	0	4	4
RAC-gamma serine/threonine-protein kinase	0	2	5	7
Serine/threonine-protein kinase SIK3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 2	0	0	5	5
Thyroid hormone receptor-associated protein 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 3	0	0	5	5
Serine/threonine-protein kinase MRCK beta	0	0	5	5
Interleukin-1 receptor-associated kinase 3	0	0	5	5
Casein kinase I isoform gamma-3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 4	0	0	5	5
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	3	0	0	3
Solute carrier family 22 member 8	0	0	0	2
Aromatase	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Androgen receptor	0	5	1	6
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	2	0	2
Albumin	0	3	2	5
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Leukotriene C4 synthase	0	0	3	3
tyrosine-protein kinase Yes	5	0	0	5
Membrane-associated progesterone receptor component 1	0	0	3	3
Serine/threonine-protein kinase 25	0	0	3	3
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	3	4
Peripheral plasma membrane protein CASK	0	0	3	3
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	3	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
Mitogen-activated protein kinase 13	0	0	3	3
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	1	3	4
Mitogen-activated protein kinase kinase kinase 7	0	0	3	3
NUAK family SNF1-like kinase 1	0	1	3	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Cyclin-dependent kinase-like 5	0	0	4	4
Serine/threonine-protein kinase 17B	0	0	3	3
Cyclin-dependent kinase 14	0	0	3	3
Serine/threonine-protein kinase OSR1	0	0	3	3
Serine/threonine-protein kinase Chk2	0	1	3	4
RAF proto-oncogene serine/threonine-protein kinase	0	1	3	4
Receptor tyrosine-protein kinase erbB-2	0	2	3	5
Macrophage colony-stimulating factor 1 receptor	0	2	3	5
Muscarinic acetylcholine receptor M1	0	1	2	3
Proto-oncogene tyrosine-protein kinase ROS	0	0	3	3
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Mast/stem cell growth factor receptor Kit	0	5	4	9
Insulin receptor-related protein	0	0	3	3
Platelet-derived growth factor receptor alpha	0	4	4	8
Vascular endothelial growth factor receptor 1	0	3	3	6
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Serine/threonine-protein kinase MAK	0	0	3	3
Cyclin-dependent kinase 11B	0	0	3	3
Fibroblast growth factor receptor 2	0	1	3	4
Receptor tyrosine-protein kinase erbB-3	0	0	3	3
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
Protein kinase C eta type	0	2	3	5
Activin receptor type-2A	0	0	3	3
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Leukocyte tyrosine kinase receptor	0	0	3	3
Tyrosine-protein kinase receptor UFO	0	1	3	4
Mitogen-activated protein kinase 4	0	0	3	3
G protein-coupled receptor kinase 4	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Vascular endothelial growth factor receptor 3	0	3	3	6
Vascular endothelial growth factor receptor 2	0	4	3	7
Serine/threonine-protein kinase receptor R3	0	0	4	4
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase TXK	0	0	3	3
Tyrosine-protein kinase ZAP-70	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Cyclin-dependent kinase 8	0	0	3	3
Tyrosine-protein kinase Blk	0	0	3	3
Cytoplasmic tyrosine-protein kinase BMX	0	0	3	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	1	3	4
Serine/threonine-protein kinase Nek4	0	0	3	3
Tyrosine-protein kinase JAK3	0	0	3	3
Death-associated protein kinase 1	0	0	3	3
Mitogen-activated protein kinase 12	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	3	5
Ephrin type-B receptor 1	0	0	3	3
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Cell division control protein 2 homolog	0	0	3	3
Calcium-dependent protein kinase 1	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase-like 1	0	0	3	3
Protein kinase C epsilon type	0	2	3	5
Angiopoietin-1 receptor	0	1	3	4
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
Protein kinase C zeta type	0	1	3	4
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	4	4
Tyrosine-protein kinase ITK/TSK	0	0	3	3
Myotonin-protein kinase	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	0	1
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Tyrosine-protein kinase Mer	0	1	4	5
cGMP-dependent protein kinase 2	0	0	3	3
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	1	3	4
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Serine/threonine-protein kinase D1	0	1	3	4
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	0	3	3
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Serine/threonine-protein kinase TNNI3K	0	0	3	3
Rab-like protein 3	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	3	4
Rho-associated protein kinase 1	0	1	0	1
Serine/threonine-protein kinase Nek5	0	0	3	3
Dual serine/threonine and tyrosine protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Cyclin-dependent kinase-like 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	3	3
Misshapen-like kinase 1	0	0	4	4
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	0	3	3
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Cyclin-dependent kinase 15	0	0	3	3
SRSF protein kinase 1	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	0	3	3
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase 33	0	0	3	3
Serine/threonine-protein kinase DCLK3	0	0	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
Homeodomain-interacting protein kinase 2	0	0	3	3
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase Nek6	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	2	3	5
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Isoleucine--tRNA ligase, mitochondrial	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	2	3	5
eIF-2-alpha kinase GCN2	0	0	3	3
Phosphatidylinositol 4-kinase beta	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
Death-associated protein kinase 2	0	0	3	3
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
ALK tyrosine kinase receptor	0	1	3	4
SRSF protein kinase 3	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	4	4
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Serine/threonine-protein kinase 24	0	0	4	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	4
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	7
Glutamate receptor ionotropic, NMDA 2A	0	2	0	6
Glutamate receptor ionotropic, NMDA 2B	0	2	0	6
Glutamate receptor ionotropic, NMDA 2C	0	2	0	7
Large neutral amino acids transporter small subunit 1	0	5	0	6
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	2	0	6
Glutamate receptor ionotropic, NMDA 3B	0	2	0	6
Glutamate receptor ionotropic, NMDA 3A	0	2	0	6
ClpP	2	0	0	2
Solute carrier family 22 member 8	0	0	0	1
GALC protein	5	0	0	5
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 3A5	0	1	0	2
Histamine H2 receptor	0	4	0	4
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Heat shock protein HSP 90-alpha	0	0	1	1
G2/mitotic-specific cyclin-B1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	1	3
Cyclin-A2	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Cyclin-A1	0	1	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Cytochrome P450 2C19	0	5	0	5
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Cereblon isoform 4	0	3	0	3
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Protein cereblon	0	4	2	9
Zinc finger protein Aiolos	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
DNA polymerase eta isoform 1	3	0	0	3
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Prothrombin	0	1	1	2
Complement C1r subcomponent	0	1	0	1
Coagulation factor X	0	1	0	1
Coagulation factor XII	0	1	0	1
Cationic trypsin	0	1	0	1
Serine protease hepsin	0	2	0	2
Cathepsin D	0	1	0	1
Trypsin-1	0	1	0	1
Complement C1s subcomponent	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Hepatocyte growth factor activator	0	2	1	3
Suppressor of tumorigenicity 14 protein	0	1	0	1
Methionine aminopeptidase 2	0	2	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
BRCA1	1	0	0	1
C-terminal-binding protein 1	1	0	0	1
Genome polyprotein	0	1	0	1
Tubulin beta-4A chain	0	1	1	3
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	3
Cholecystokinin receptor type A	0	3	1	4
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Geranylgeranyl pyrophosphate synthase	0	3	0	4
Farnesyl pyrophosphate synthase	0	4	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	3	0	3
Myosin light chain kinase, smooth muscle	0	0	2	2
Tubulin alpha-1A chain	0	0	2	2
Receptor protein-tyrosine kinase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
Focal adhesion kinase 1	0	0	0	1
Cyclin-H	0	1	0	1
CDK-activating kinase assembly factor MAT1	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M3	0	0	2	2
Muscarinic acetylcholine receptor M4	0	0	2	2
Muscarinic acetylcholine receptor M5	0	0	2	2
Muscarinic acetylcholine receptor M2	0	0	2	2
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	4	0	4
Muscarinic acetylcholine receptor M4	0	0	1	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	3	0	3
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	3
Phospholipase A-2-activating protein	0	2	0	2
beta-2 adrenergic receptor	2	0	1	3
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Steryl-sulfatase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	6	9
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Muscarinic acetylcholine receptor M2	0	3	1	4
5-hydroxytryptamine receptor 1A	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Beta-1 adrenergic receptor	0	3	1	5
D(3) dopamine receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1B	0	6	0	6
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Translocator protein	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Protein delta homolog 1	0	1	1	2
Cyclin-dependent kinase 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Splicing factor 3B subunit 3	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Spike glycoprotein	0	0	1	1
streptokinase A precursor	0	0	2	2
Transmembrane protease serine 2	0	0	1	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Endolysin	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Butyrophilin subfamily 3 member A1	0	0	1	2
Farnesyl diphosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (528)

Protein Targets (1,688)

Hemangioendothelioma

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (528)

Drugs Studied (239)

Protein Targets (1,688)