An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the function of aconitase (EC 4.2.1.3).
ChEBI ID: 62608
| Member | Definition | Class |
|---|---|---|
| fluoroacetic acid | A haloacetic acid that is acetic acid in which one of the methyl hydrogens is substituted by fluorine. | fluoroacetic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 98 (39.36) | 18.7374 |
| 1990's | 31 (12.45) | 18.2507 |
| 2000's | 60 (24.10) | 29.6817 |
| 2010's | 52 (20.88) | 24.3611 |
| 2020's | 8 (3.21) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (0.77%) | 5.53% |
| Reviews | 12 (4.60%) | 6.00% |
| Case Studies | 15 (5.75%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 232 (88.89%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 43.2771 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 61.6825 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 48.5577 | 1 | 2 |