A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Reference |
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| "A case of vulvar paraganglioma is reported." | ( Colgan, TJ; Dardick, I; O'Connell, G, 1991) |
| "Paragangliomas are tumours arising from paraganglionic tissue dispersed from the base of the skull to the pelvic diaphragm." | ( Falke, TH; Pauwels, EK; van Erkel, AR; van Gils, AP, 1994) |
| "Paragangliomas are rare neuroendocrine tumors and the malignant behaviour, higher than pheochromocytomas, is based on metastases or local recurrence." | ( Farthouat, P; Meusnier, F; Platel, JP; Pourrière, M; Thouard, H, 1997) |
| "Thoracic paragangliomas are a rare cause of hypertension." | ( Engelhardt, D; Rau, HG; Ritter, MM; Szukics, B, 2000) |
| "Paragangliomas are rare tumors of the paraganglia composed of specialized neural crest cells arising in association with sympathetic ganglia." | ( Krywicki, RF; Pipas, JM, 2000) |
| "Malignant paraganglioma is a rare and slow growing tumour of neuroendocrine origin." | ( Bomanji, JB; Costa, DC; Coulter, C; Ell, PJ; Gacinovic, S; Gaze, MN; Hyder, SW, 2001) |
| "Hereditary paragangliomas are usually benign tumors of the autonomic nervous system that are composed of cells derived from the primitive neural crest." | ( Corvol, P; Favier, J; Gimenez-Roqueplo, AP; Jeunemaitre, X; Mourad, JJ; Plouin, PF; Rötig, A; Rustin, P, 2001) |
| "Paragangliomas are rare tumors that arise from extraadrenal chromaffin cells." | ( Ebersold, MJ; Erickson, D; Grant, CS; Kudva, YC; Thompson, GB; van Heerden, JA; Young, WF, 2001) |
| "Primary pulmonary paragangliomas are very uncommon tumors." | ( Hsu, LH; Hsu, WH; Tsou, MH; You, DL, 2002) |
| "Paraganglioma is a rare tumor of the paraganglioma system arising from undifferentiated cells of the neural crest." | ( Blin, V; Enon, B; Picquet, J; Rohmer, V, 2002) |
| "Nasal paragangliomas are extremely rare." | ( Askar, I; Kilinc, N; Oktay, MF, 2003) |
| "Cervical paragangliomas are rare tumors derived from neural crest cells." | ( Kanazawa, A; Kishimoto, C; Konishi, K; Takayama, M; Yamane, H, 2004) |
| "Paraganglioma is a rare neuroendocrine neoplasm observed in patients of all ages but it has not been characterized in children." | ( Buonuomo, V; D'Urzo, C; Manzoni, C; Pintus, C; Rando, G; Ruggiero, A, 2004) |
| "Intracardiac paragangliomas are rare endocrine tumors that are usually benign and can be cured by surgical resection." | ( Al-Saghir, Y; Cho, SR; McGann, C; Schaff, H; Shean, F; Tazelaar, H; Young, W, 2005) |
| "Paragangliomas are tumours that arise within the sympathetic nervous system originating from the neural crest." | ( Bley, TA; Brink, I; Hoegerle, S; Klisch, J, 2005) |
| "Laryngeal paraganglioma is a rare vascular neuroendocrine benign tumour." | ( Bertoletti, F; Bertolini, G; Capolunghi, B; Cascio, F; Grillo della Berta, L; Tinelli, N, 2005) |
| "Paragangliomas are neuroendocrine tumors that arise in relation to the sympathetic or parasympathetic ganglia of the autonomic nervous system." | ( Cesnorek, S; Kelly, L; Ram, R; Saadat, P; Vadmal, M, 2006) |
| "Paragangliomas are rare neoplasms arising from undifferentiated cells of the primitive neural crest." | ( Maeda, S; Mizoguchi, Y; Yamamoto, N, 2007) |
| "The paraganglioma is a rare tumour that can sometimes develop near to the pancreatic gland and can occasionally mimic an intra pancreatic mass." | ( Crozes, C; Faucompret, S; Milou, F; Pavic, M; Perrot, G; Vincent, E, 2007) |
| "Paragangliomas are tumors arising from the extra-adrenal paragangliar neural crest cells." | ( Balint, B; Colovic, M; Elezovic, I; Ivanovic, B; Jevtic, M; Krstic, M; Milenkovic, R; Pavlovic, M; Petrovic, M; Popovic, V; Suvajdzic, N; Todorovic, M, 2008) |
| "Paragangliomas are tumors that develop from extraadrenal chromaffin cells." | ( Asa, SL; Broom, R; Evans, A; Ezzat, S; Freeman, M; Joshua, AM; Knox, JJ, 2009) |
| "Paragangliomas are rarer still and, in a minority of cases (20%), are known to be caused by errors in the SDHD gene." | ( Dornhoffer, J; Hartzell, LD; McKelvey, KD; Van Hemert, RL, 2008) |
| "Paragangliomas are rare tumors arising from extraadrenal chromaffin cells." | ( Badaoui, R; Delmas, J; Dhahri, A; Dupont, H; Fumery, M; Mahjoub, Y; Regimbeau, JM; Riboulot, M, 2011) |
| "Paragangliomas are rare, benign or less frequently malignant tumors developing from cells of the paraganglia, a diffuse neuroendocrine system dispersed from skull base to the pelvic floor." | ( Frysz-Naglak, D; Krysiak, R; Okopień, B, 2011) |
| "Ten percent of paragangliomas are malignant and one-third occurs in a genetic background." | ( Borson-Chazot, F; Giraud, S; Joly, MO; Lombard-Bohas, C; Nozières, C; Riou, JP; Scoazec, JY; Simon, C; Walter, T, 2012) |
| "Urinary bladder paragangliomas are rare tumors, with malignant ones being still rarer." | ( Aggarwal, MM; Bhattacharya, A; Kashyap, R; Mandal, AK; Manohar, K; Mittal, BR, 2012) |
| "Paraganglioma is a neuroendocrine neoplasm that may develop at various body sites, including the head, neck, thorax, and abdomen." | ( Kim, JH; Lee, IJ; Lim, H; Park, MC, 2012) |
| "A non-functioning paraganglioma is usually benign, however, it may cause distant metastases." | ( Hashimoto, N; Kanai, H; Ogawa, K; Suzuki, S; Yamashita, N, 2012) |
| "Paraganglioma is a rare neuroendocrine neoplasm observed in patients of all ages, with an estimated incidence of 3/1,000,000 population." | ( Feng, N; Gao, HD; Li, X; Liu, WZ; Liu, ZL; Shi, LJ, 2013) |
| "Paragangliomas are rare benign neuroendocrine tumors, and 80% of all paragangliomas are either carotid body tumors or glomus jugulare tumors." | ( Bal, C; Damle, N; Gupta, SK; Karunanithi, S; Singla, S, 2014) |
| "Urinary bladder paragangliomas are exceedingly rare tumors." | ( Arora, S; Dhull, VS; Jain, TK; Karunanithi, S; Kumar, R, 2014) |
| "Thyroid paraganglioma is a finite entity, which must be differentiated from medullary thyroid carcinoma, because medical, surgical, and genetic management for each is different." | ( Akslen, LA; Arola, J; Barbareschi, M; Bausch, B; Brauckhoff, M; Castinetti, F; Cecchini, ME; Demattè, S; Eng, C; Fassina, A; Hasse-Lazar, K; Januszewicz, A; Jarzab, B; Krajewska, J; Lange, D; Leijon, H; Luettges, J; Malinoc, A; Neumann, HP; Opocher, G; Peczkowska, M; Pennelli, G; Prejbisz, A; Roszkowska-Purska, K; Sartorato, P; Schalin-Jäntti, C; Schiavi, F; Spiazzi, G; Strate, T; Taschin, E; von Dobschuetz, E, 2015) |
| "Spinal paragangliomas are extremely rare tumors, most frequently involving the cauda equina and the filum terminale." | ( Deng, X; Fang, J; Li, G; Wu, L; Xu, Y; Yang, C; Yang, T, 2015) |
| "Paragangliomas are derived from neurosecretory cells believed to be of neural crest origin." | ( Chen, Z; Feng, H; Han, JQ; Li, JM; Liu, HL; Qin, T; Sun, S; Wang, XW; Wu, CS, 2015) |
| "Paragangliomas are cromaffin tumors arising from the neural crest cells of parasympathetic or sympathetic ganglia." | ( Andrello, L; Osculati, A; Visonà, SD, 2015) |
| "Thyroid paragangliomas are extremely rare tumors arising from the inferior laryngeal paraganglia." | ( Policarpio-Nicolas, ML; Zhang, W, 2015) |
| "OBJECT Paragangliomas are highly vascular head and neck tumors for which preoperative embolization is often considered to facilitate resection." | ( Davis, BJ; He, L; Ladner, TR; Mocco, J; Wanna, GB; Yang, GL, 2016) |
| "Paraganglioma is a rare neuroendocrine neoplasm that may arise from the extra-adrenal autonomic paraganglia." | ( Dragović, T; Hajduković, Z; Kovačević, B; Kuzmić-Janković, S; Marinković, D; Milović, N; Prelević, R, 2015) |
| "A paraganglioma is an extra-adrenal pheochromocytoma that contains chromaffin cells and is thus capable of producing catecholamines." | ( Barank, D; Cho, J; Davalos, EA; Dave, H; Shen, H; Shim, J, 2016) |
| "Pheochromocytomas/paragangliomas are somatostatin receptor 2-overexpressing tumors." | ( Chui, CH; Janssen, I; Millo, CM; Pacak, K; Wolf, KI, 2017) |
| "Urinary bladder paragangliomas are very rare, and the majority are hormonally active." | ( Darvishi, P; Mithqal, A; Rehm, P, 2017) |
| "Paragangliomas are generally benign, slow-growing tumors." | ( Murata, H; Nagashima, Y; Ohtake, M; Tateishi, K; Yamamoto, T; Yamanaka, S, 2018) |
| "Paraganglioma is rare in children and most pheochromocytomas originate in the adrenal gland." | ( Wang, W; Xu, C; Yang, G; Yuan, M, 2018) |
| "Head and neck paragangliomas are rare and often asymptomatic tumors and mostly present as painless masses." | ( Dattagupta, S; Parida, GK; Shamim, SA; Tripathi, M; Tripathy, S, 2019) |
| "Carotid body paragangliomas are mostly benign tumors with very rare propensity to metastasize to lymph nodes, bones, liver, and lungs." | ( Bal, C; Damle, NA; Naranje, P; Shamim, SA; Tripathi, M; Tripathy, S, 2019) |
| "Paragangliomas are rare tumours of neural crest origin that express high levels of somatostatin receptor." | ( Bomanji, J; Caplin, ME; Gnanasegaran, G; Navalkissoor, S; Novruzov, F; Priftakis, D; Skoura, E, 2020) |
| "Paraganglioma is a rare neuroendocrine tumor arising from undifferentiated cells of the primitive neural crest." | ( Wang, J; Zhong, L, 2020) |
| "Hence, paragangliomas are occasionally misdiagnosed, and this results in unanticipated intraoperative hypertensive crisis." | ( Cherian, KE; Johnson, JT; Kapoor, N; Paul, TV, 2020) |
| "Mediastinal paragangliomas are very uncommon neuroendocrine neoplasms." | ( Gonzalez, JN; Nguyen, DM; Villamizar, NR, 2020) |
| "Paragangliomas are extra-adrenal catecholamine-producing tumours." | ( Iyyadurai, R; John, K; Nawahirsha, S; Sunil V, N, 2020) |
| "Vaginal paraganglioma is very rare." | ( Chen, L; Jing, H; Li, F; Zheng, K; Zhu, S, 2021) |
| "Vaginal paraganglioma are rare, atypical, solitary tumors which originate from the female genital tract." | ( Fan, H; Fan, J; Seery, S; Wang, W; Wang, Z; Zhang, Y, 2021) |
| "Primary cardiac paragangliomas are rare tumors." | ( April, G; Arsenault, F; Beaulieu, A; Beauregard, JM; Buteau, FA; Desaulniers, M; Huot Daneault, A; Turcotte, É, 2021) |
| "Paragangliomas are rare neuroendocrine tumors originating from neural crest-derived paraganglion cells." | ( Du, Z; Wang, Y; Xiong, J; Yin, B; Zhang, Y, 2022) |
| "Paragangliomas are mostly benign tumors originating from the sympathetic or parasympathetic ganglions, but malignant forms are also known." | ( Bajnok, L; Benkő, I; Bódis, B; Gulyás, E; Kálmán, E; Kittka, B; Mezősi, E; Nemes, O; Schmidt, E; Semjén, D; Szabados, S; Szukits, S, 2022) |
| "Cardiac paragangliomas are exceedingly rare." | ( Hoo, CE; Hsu, CP; Huang, CY; Huang, PH; Kuo, CS; Yang, AH, 2022) |
| "Multifocal paragangliomas are scarcely reported in the literature." | ( Di, XP; Li, X; Wu, K; Xiong, SC; Zhang, MN, 2022) |
| "Paragangliomas are extremely rare neuroendocrine tumors arising from ganglia." | ( Li, J; Liu, G; Wan, P; Zhang, B, 2022) |
| "Paraganglioma is a less prevalent disease, and paraganglioma with only secreting interleukin-6 (IL-6) has not been previously reported." | ( Cui, C; Guan, M; Wang, C; Zhang, S, 2023) |