An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97).
ChEBI ID: 78691
| Member | Definition | Class |
|---|---|---|
| histidinol | An amino alcohol that is propanol substituted by 1H-imidazol-4-yl group at position 3 and an amino group at position 2 (the 2S stereoisomer). | L-histidinol |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 88 (65.19) | 18.7374 |
| 1990's | 29 (21.48) | 18.2507 |
| 2000's | 11 (8.15) | 29.6817 |
| 2010's | 5 (3.70) | 24.3611 |
| 2020's | 2 (1.48) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 4 (2.68%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 145 (97.32%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 35.4813 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 1,530.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Histidinol dehydrogenase | Brucella suis 1330 | Km | 12.0000 | 1 | 1 |