trifluoperazine has been researched along with Parkinson Disease in 19 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Nguyen, DT | 1 |
| Olzomer, EM | 1 |
| Poon, GP | 1 |
| Cole, NJ | 1 |
| Puvanendran, A | 1 |
| Phillips, BR | 1 |
| Hesselson, D | 1 |
| Höllerhage, M | 1 |
| Goebel, JN | 1 |
| de Andrade, A | 1 |
| Hildebrandt, T | 1 |
| Dolga, A | 1 |
| Culmsee, C | 1 |
| Oertel, WH | 1 |
| Hengerer, B | 1 |
| Höglinger, GU | 1 |
| BORENSTEIN, P | 1 |
| DABBAH, M | 1 |
| BLES, G | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Zweig, RM | 1 |
| Davis, PH | 1 |
| Shiwach, RS | 1 |
| Woods, S | 1 |
| Kristal, BS | 1 |
| Conway, AD | 1 |
| Brown, AM | 1 |
| Jain, JC | 1 |
| Ulluci, PA | 1 |
| Li, SW | 1 |
| Burke, WJ | 1 |
| Martin, IC | 1 |
| Hoehn, MM | 1 |
| Crowley, TJ | 1 |
| Rutledge, CO | 1 |
| Paulson, GW | 1 |
| Rizvi, CA | 1 |
| Crane, GE | 1 |
| Kurth, MC | 1 |
| Langston, JW | 1 |
| Tetrud, JW | 1 |
| Hershon, HI | 1 |
| Kennedy, PF | 1 |
| McGuire, RJ | 1 |
| Tkachev, RA | 1 |
| Markova, ED | 1 |
| Gotovtseva, EV | 1 |
| Barkhatova, VP | 1 |
| Ivanova-Smolenskaia, IA | 1 |
| Morrison, AB | 1 |
| Webster, RA | 1 |
| Ambani, LM | 1 |
| Van Woert, MH | 1 |
| Bowers, MB | 1 |
| Chase, TN | 1 |
| Schnur, JA | 1 |
| Gordon, EK | 1 |
| Jenkins, R | 1 |
| Hader, M | 1 |
| Ekdawi, MY | 1 |
| Fowke, R | 1 |
3 trials available for trifluoperazine and Parkinson Disease
| Article | Year |
|---|---|
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparat | 1975 |
Tardive dyskinesia as a possible sequel of long-term therapy with phenothiazines.
Topics: Adolescent; Child; Chlorpromazine; Clinical Trials as Topic; Diagnosis, Differential; Dystonia Muscu | 1975 |
Persistence of extra-pyramidal disorders and psychiatric relapse after withdrawal of long-term phenothiazine therapy.
Topics: Basal Ganglia Diseases; Clinical Trials as Topic; Factor Analysis, Statistical; Female; Humans; Male | 1972 |
16 other studies available for trifluoperazine and Parkinson Disease
| Article | Year |
|---|---|
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy.
Topics: Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Behavior, Animal; C | 2017 |
Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity.
Topics: alpha-Synuclein; Antipsychotic Agents; Autophagy; Cells, Cultured; Dopaminergic Neurons; Humans; Lew | 2014 |
[Apropos of the ultimate specificity of terrain in the appearance of extrapyramidal syndromes induced by neuroleptic agents].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Extrapyramidal Tracts; Haloperidol; Humans; Parkinson | 1962 |
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp | 1967 |
When selegiline is prescribed, Stelazine may be mistakenly dispensed.
Topics: Drug Prescriptions; Humans; Medication Errors; Parkinson Disease; Selegiline; Trifluoperazine | 1993 |
Risperidol and withdrawal bruxism in Lewy body dementia.
Topics: Aged; Antipsychotic Agents; Bruxism; Delusions; Dopamine Antagonists; Humans; Male; Parkinson Diseas | 1998 |
Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminobenzoic Acid; Aminobenzoates; Animals; Aristolochic Acids; Ce | 2001 |
The Parkinsonian syndrome and its dopamine correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Dopamine; Extrapyramidal Tracts; Female; Homovanillic A | 1977 |
"Stelazine" versus "selegiline"--a hazard in prescription writing.
Topics: Aged; Drug Prescriptions; Female; Humans; Male; Medication Errors; Parkinson Disease; Selegiline; Tr | 1990 |
[Principles of the pathogenetic therapy of congenital extrapyramidal diseases].
Topics: Adolescent; Adult; Atropine; Basal Ganglia Diseases; Chelating Agents; Chronic Disease; Dihydroxyphe | 1973 |
Drug-induced experimental Parkinsonism.
Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Dr | 1973 |
Physostigmine effects on phenothiazine-induced extrapyramidal reactions.
Topics: Adult; Antiparkinson Agents; Chlorpromazine; Drug Hypersensitivity; Extrapyramidal Tracts; Female; H | 1973 |
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
Topics: Amines; Brain; Chlorpromazine; Extrapyramidal Tracts; Female; Humans; Hydroxyindoleacetic Acid; Move | 1970 |
Laevo-dopa for Parkinsonism.
Topics: Dihydroxyphenylalanine; Haloperidol; Humans; Parkinson Disease; Trifluoperazine | 1970 |
Antiparkinsonism medication for the phenothiazine-induced pyramidal-extrapyramidal syndrome in elderly brain-damaged patients.
Topics: Aged; Brain Damage, Chronic; Chlorpromazine; Female; Humans; Male; Parkinson Disease; Perphenazine; | 1965 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic | 1966 |