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trifluoperazine and Pituitary Neoplasms

trifluoperazine has been researched along with Pituitary Neoplasms in 16 studies

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"When trifluoperazine was incubated with cytosol, both the high and low affinity forms of cyclic AMP phosphodiesterase were inhibited competitively with calculated Ki of 4."1.27Effects of calmodulin antagonists on hormone release and cyclic AMP levels in GH3 pituitary cells. ( Gautvik, KM; Gordeladze, J; Haug, E; Sand, O; Sletholt, K, 1987)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's2 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ng, KW1
Lee, J1
Swapna, V1
Brostrom, MA3
Brostrom, CO2
Bocckino, SB1
Green, SS1
Drust, DS1
Martin, TF1
Thaw, C1
Wittlin, SD1
Gershengorn, MC1
Sand, O2
Sletholt, K5
Gautvik, KM5
Haug, E5
Antoni, FA1
Shipston, MJ1
Smith, SM1
Lamberts, SW1
van Koetsveld, PM1
Hofland, LJ1
Wolfe, SE2
Heisler, S1
Gordeladze, J2
Koenig, RJ1
Magnusson, C1
Lehmann, LS1

Other Studies

16 other studies available for trifluoperazine and Pituitary Neoplasms

ArticleYear
Management of a patient with schizophrenia and underlying pituitary macroadenoma.
    Annals of the Academy of Medicine, Singapore, 2010, Volume: 39, Issue:11

    Topics: Adenoma; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bromocriptine; Dopamine Antagon

2010
Ca2+ and hormones interact synergistically to stimulate rapidly both prolactin production and overall protein synthesis in pituitary tumor cells.
    Journal of cellular physiology, 1984, Volume: 121, Issue:2

    Topics: Amino Acids; Animals; Calcium; Cell Line; Drug Synergism; Egtazic Acid; Kinetics; Neoplasm Proteins;

1984
Thyrotropin-releasing hormone rapidly and transiently stimulates cytosolic calcium-dependent protein phosphorylation in GH3 pituitary cells.
    The Journal of biological chemistry, 1982, Jul-10, Volume: 257, Issue:13

    Topics: Animals; Calcium; Calmodulin; Cell Line; Cytosol; Egtazic Acid; Kinetics; Neoplasm Proteins; Neoplas

1982
Tetracaine, propranolol and trifluoperazine inhibit thyrotropin releasing hormone-induced prolactin secretion from GH3 cells by displacing membrane calcium: further evidence that TRH acts to mobilize cellular calcium.
    Endocrinology, 1982, Volume: 111, Issue:6

    Topics: Animals; Calcium; Cell Line; Cell Membrane; Pituitary Neoplasms; Prolactin; Propranolol; Rats; Tetra

1982
Trifluoperazine blocks calcium-dependent action potentials and inhibits hormone release from rat pituitary tumour cells.
    European journal of pharmacology, 1982, Dec-24, Volume: 86, Issue:2

    Topics: Action Potentials; Animals; Calcium; Growth Hormone; In Vitro Techniques; Neoplasms, Experimental; P

1982
Inhibitory role for calcineurin in stimulus-secretion coupling revealed by FK506 and cyclosporin A in pituitary corticotrope tumor cells.
    Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cyclosporin

1993
The effect of clozapine on prolactin secretion at the level of the lactotroph.
    Life sciences, 1990, Volume: 46, Issue:14

    Topics: Animals; Cells, Cultured; Clozapine; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; Fem

1990
Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. II. Blockade of voltage-dependent Ca2+ channels.
    Molecular pharmacology, 1986, Volume: 29, Issue:4

    Topics: Action Potentials; Amino Acids; Animals; Calcium; Cell Line; Chlorpromazine; Ion Channels; Membrane

1986
Calmodulin antagonists inhibit dihydropyridine calcium channel activator (BAY-K-8644) induced cGMP synthesis in pituitary tumor cells.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
On the involvement of cyclic AMP and extracellular Ca2+ in the regulation of hormone release from rat pituitary tumour (GH3) cells in culture.
    Bioscience reports, 1987, Volume: 7, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Cobalt; Cyclic AM

1987
Effects of trifluoperazine on prolactin release and cyclic AMP formation and degradation in GH4C1 pituitary cells.
    Acta endocrinologica, 1987, Volume: 116, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Calcium; Cell Line; Cyclic AMP; Pit

1987
Regulation of thyroxine 5'-deiodinase by thyroid hormones and activators of protein kinase C in GH4C1 cells.
    Endocrinology, 1986, Volume: 118, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cell Line; Colforsin; Cyclic GMP; Dose-

1986
Effects of metabolic inhibitors on hormone release, cyclic AMP levels, and oxygen consumption in rat pituitary cells in culture.
    Acta endocrinologica, 1987, Volume: 115, Issue:1

    Topics: Animals; Antimycin A; Cell Line; Cyclic AMP; Dinitrophenols; Growth Hormone; Iodoacetates; Oxygen Co

1987
Effects of calmodulin antagonists on hormone release and cyclic AMP levels in GH3 pituitary cells.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Division; Cell Line; Chlorprom

1987
Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. I. Ca2+-dependent inhibition of amino acid incorporation.
    Molecular pharmacology, 1986, Volume: 29, Issue:4

    Topics: Acetylcholine; Amino Acids; Animals; Bromocriptine; Calcium; Carbachol; Cell Line; Chlorpromazine; I

1986
Depersonalization.
    The American journal of psychiatry, 1974, Volume: 131, Issue:11

    Topics: Adrenal Insufficiency; Adult; Anger; Anxiety; Cannabis; Chlorpromazine; Compulsive Behavior; Defense

1974