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naphthols

Any hydroxynaphthalene derivative that has a single hydroxy substituent.

ChEBI ID: 25392

Members (28)

MemberDefinitionRole
(s)-binol(S)-(-)-1,1'-Bi-2-naphthol
1-[[(1-methyl-2-benzimidazolyl)amino]methyl]-2-naphthalenol1-[[(1-methyl-2-benzimidazolyl)amino]methyl]-2-naphthalenol
1-hydroxy-2-naphthoic acidA naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.1-hydroxy-2-naphthoic acid
1-nitroso-2-naphthol1-Nitroso-2-naphthol
2-[2-hydroxy-6,7-dimethoxy-4-(4-morpholinyl)-1-naphthalenyl]-N-phenylacetamide2-[2-hydroxy-6,7-dimethoxy-4-(4-morpholinyl)-1-naphthalenyl]-N-phenylacetamide
2-hydroxy-1-naphthaldehydeA member of the class of naphthaldehydes that is naphthalene-1-carbaldehyde substituted by a hydroxy group at position 2. Active core of sirtinol (CHEBI:73158).2-hydroxy-1-naphthaldehyde
2,6-dihydroxynaphthalene2,6-Dihydroxynaphthalene
4-hydroxypropranolol4'-hydroxypropanolol
6-bromo-2-naphtholA member of the class of naphthols that is 2-naphthol carrying an additional bromo substituent at position 6.6-bromo-2-naphthol
7-amino-4-hydroxy-2-naphthalenesulfonic acidAn aminonaphthalenesulfonic acid that is 2-naphthalenesulfonic acid substituted by an amino group at position 7 and a hydroxy group at position 4 respectively.7-amino-4-hydroxy-2-naphthalenesulfonic acid
allenolic acidAllenolic acid
aminaftoneaminaphthone
dihydrobunolol(+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol
dioncophylline cAn isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 5-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 5-hydroxy-4-methoxy-2-methylnaphthalen-1-yl group. It is a naphthylisoquinoline alkaloid isolated from the roots and stem barks of Triphyophyllum peltatum and exhibits antimalarial activity.dioncophylline C
IPA-3An organic disulfide obtained by oxidative dimerisation of 1-sulfanylnaphthalen-2-ol.IPA-3
lasofoxifeneA member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women.lasofoxifene
N-[(2-chlorophenyl)-(2-hydroxy-1-naphthalenyl)methyl]butanamideN-[(2-chlorophenyl)-(2-hydroxy-1-naphthalenyl)methyl]butanamide
N-[(2-hydroxy-1-naphthalenyl)-(4-methoxyphenyl)methyl]-2-methylpropanamideN-[(2-hydroxy-1-naphthalenyl)-(4-methoxyphenyl)methyl]-2-methylpropanamide
N-[(2-hydroxy-1-naphthalenyl)-(4-methylphenyl)methyl]cyclohexanecarboxamideN-[(2-hydroxy-1-naphthalenyl)-(4-methylphenyl)methyl]cyclohexanecarboxamide
N-[[(5-hydroxy-1-naphthalenyl)amino]-sulfanylidenemethyl]-2-furancarboxamideN-[[(5-hydroxy-1-naphthalenyl)amino]-sulfanylidenemethyl]-2-furancarboxamide
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazideA carbohydrazide resulting from the formal condensation of the hydrazone moiety of 3,4-dihydroxybenzaldehyde hydrazone with the carboxy group of 3-hydroxy-2-naphthoic acid. It is a cell-permeable, reversible noncompetitive inhibitor of the GTPase activity of dynamin 1 and 2 and Drp1 (mitochondrial), while exhibiting no significant effect against two other small GTPases, MxA and Cdc42.dynasore
naphthol yellowA naphthalenesulfonic acid that is naphthalene-2-sulfonic acid substituted by nitro groups at positions 5 and 7 as well as a hydroxy group at position 8. The disodium salt is the biological stain 'naphthol yellow S'.flavianic acid
nepodinNepodin
ponceau mxA naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid carrying additional hydroxy and (2,4-dimethylphenyl)diazenyl substituents at positions 3 and 4 respectively. The disodium salt is the biological stain 'acid red 26'.4-[(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonic acid
scarlet redA bis(azo) compound that is 2-naphthol substituted at position 1 by a {2-methyl-4-[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound lipids in paraffin sections.Sudan IV
sirtinolA benzamide obtained by formal condensation of the carboxy group of 2-{[(2-hydroxy-1-naphthyl)methylene]amino}benzoic acid with the amino group of 1-phenylethylamine.sirtinol
sudan iiiA bis(azo) compound that is 2-naphthol substituted at position 1 by a 4-{[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound lipids in paraffin sections.Sudan III
vitamin k54-Amino-2-methyl-1-naphthol

Research

Studies (918)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990183 (19.93)18.7374
1990's73 (7.95)18.2507
2000's230 (25.05)29.6817
2010's371 (40.41)24.3611
2020's61 (6.64)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials30 (2.86%)5.53%
Reviews43 (4.10%)6.00%
Case Studies9 (0.86%)4.05%
Observational0 (0.00%)0.25%
Other966 (92.18%)84.16%