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trifluoperazine and Bone Loss, Osteoclastic

trifluoperazine has been researched along with Bone Loss, Osteoclastic in 5 studies

Research Excerpts

ExcerptRelevanceReference
"While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents."1.48Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells. ( Chen, A; Fan, Y; Jalali, A; Li, BY; Liu, S; Minami, K; Nakshatri, H; Ogawa, K; Yokota, H, 2018)
"Tamoxifen inhibits bone resorption by disrupting calmodulin-dependent processes."1.31Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin. ( McDonald, JM; McKenna, MA; Thames, AM; Williams, JP, 2000)
"Bone resorption was reversibly inhibited by tamoxifen, 4-hydroxytamoxifen, and trifluoperazine with IC50 values of approximately 1 microM."1.29Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors. ( Blair, HC; Jordan, SE; McDonald, JM; McKenna, MA; Williams, JP, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, S1
Fan, Y1
Chen, A1
Jalali, A1
Minami, K1
Ogawa, K1
Nakshatri, H1
Li, BY1
Yokota, H1
Williams, JP3
Blair, HC2
McKenna, MA3
Jordan, SE2
McDonald, JM3
Radding, W1
Thames, AM1
Tyan, ML1
Blahd, WH1

Other Studies

5 other studies available for trifluoperazine and Bone Loss, Osteoclastic

ArticleYear
Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells.
    Cancer research, 2018, 07-15, Volume: 78, Issue:14

    Topics: Animals; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast; Breast Neoplasms; Cell Culture Tec

2018
Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors.
    The Journal of biological chemistry, 1996, May-24, Volume: 271, Issue:21

    Topics: Animals; Biological Transport; Bone Resorption; Calmodulin; Cell Membrane; Cells, Cultured; Chickens

1996
Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H(+)-ATPase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding.
    Journal of cellular biochemistry, 1997, Sep-01, Volume: 66, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Benzopyrans; Bone Resorption; Calmodulin; Centchroman; Cyclic Nucl

1997
Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2000, Volume: 78, Issue:6

    Topics: Animals; Bone Resorption; Calmodulin; Cell Membrane; Cells, Cultured; Chickens; Cytosol; Down-Regula

2000
Age-related osteopenia in the mouse: effects of an H1 blocker, a phenothiazine, and promethazine.
    Mechanisms of ageing and development, 1986, Volume: 35, Issue:3

    Topics: Age Factors; Animals; Bone Diseases, Metabolic; Bone Resorption; Chlorpheniramine; Female; Histamine

1986