trifluoperazine has been researched along with Bone Loss, Osteoclastic in 5 studies
Excerpt | Relevance | Reference |
---|---|---|
"While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents." | 1.48 | Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells. ( Chen, A; Fan, Y; Jalali, A; Li, BY; Liu, S; Minami, K; Nakshatri, H; Ogawa, K; Yokota, H, 2018) |
"Tamoxifen inhibits bone resorption by disrupting calmodulin-dependent processes." | 1.31 | Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin. ( McDonald, JM; McKenna, MA; Thames, AM; Williams, JP, 2000) |
"Bone resorption was reversibly inhibited by tamoxifen, 4-hydroxytamoxifen, and trifluoperazine with IC50 values of approximately 1 microM." | 1.29 | Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors. ( Blair, HC; Jordan, SE; McDonald, JM; McKenna, MA; Williams, JP, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Liu, S | 1 |
Fan, Y | 1 |
Chen, A | 1 |
Jalali, A | 1 |
Minami, K | 1 |
Ogawa, K | 1 |
Nakshatri, H | 1 |
Li, BY | 1 |
Yokota, H | 1 |
Williams, JP | 3 |
Blair, HC | 2 |
McKenna, MA | 3 |
Jordan, SE | 2 |
McDonald, JM | 3 |
Radding, W | 1 |
Thames, AM | 1 |
Tyan, ML | 1 |
Blahd, WH | 1 |
5 other studies available for trifluoperazine and Bone Loss, Osteoclastic
Article | Year |
---|---|
Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells.
Topics: Animals; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast; Breast Neoplasms; Cell Culture Tec | 2018 |
Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors.
Topics: Animals; Biological Transport; Bone Resorption; Calmodulin; Cell Membrane; Cells, Cultured; Chickens | 1996 |
Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H(+)-ATPase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding.
Topics: Animals; Anticarcinogenic Agents; Benzopyrans; Bone Resorption; Calmodulin; Centchroman; Cyclic Nucl | 1997 |
Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin.
Topics: Animals; Bone Resorption; Calmodulin; Cell Membrane; Cells, Cultured; Chickens; Cytosol; Down-Regula | 2000 |
Age-related osteopenia in the mouse: effects of an H1 blocker, a phenothiazine, and promethazine.
Topics: Age Factors; Animals; Bone Diseases, Metabolic; Bone Resorption; Chlorpheniramine; Female; Histamine | 1986 |