Page last updated: 2024-11-05

trifluoperazine and ER-Negative PR-Negative HER2-Negative Breast Cancer

trifluoperazine has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 2 studies

Research Excerpts

ExcerptRelevanceReference
"Trifluoperazine (TFP) is an approved antipsychotic drug with good bioavailability in brain and had shown anticancer effect in several types of cancer."1.48The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis. ( Feng, Z; Gao, T; Hu, X; Lei, Q; Peng, C; Ran, Z; Wang, Q; Wang, R; Xia, Y; Xie, Z; Xu, F; Xue, Q; Yang, N; Yang, Y; Yu, L; Zeng, Z, 2018)
"Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer."1.43Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo. ( Berek, JS; Chung, YM; Hu, MC; Ma, J; Park, SH; Yang, Q, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feng, Z1
Xia, Y1
Gao, T1
Xu, F1
Lei, Q1
Peng, C1
Yang, Y1
Xue, Q1
Hu, X1
Wang, Q1
Wang, R1
Ran, Z1
Zeng, Z1
Yang, N1
Xie, Z1
Yu, L1
Park, SH1
Chung, YM1
Ma, J1
Yang, Q1
Berek, JS1
Hu, MC1

Other Studies

2 other studies available for trifluoperazine and ER-Negative PR-Negative HER2-Negative Breast Cancer

ArticleYear
The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
    Cell death & disease, 2018, 09-26, Volume: 9, Issue:10

    Topics: Animals; Antipsychotic Agents; Apoptosis; Brain; Brain Neoplasms; Caspase 3; Cell Cycle Checkpoints;

2018
Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Animals; Apoptosis; Bepridil; Breast Neoplasms; Cell Nucleus; Dopamine; Female; Forkhead Box Protein

2016