The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. [GOC:dph, GOC:mah, ISBN:0198506732]
| Compound | Definition | Classes | Roles |
|---|
| thyroxine | | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | mitogen |
| 1-anilino-8-naphthalenesulfonate | 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8. | aminonaphthalene;
naphthalenesulfonic acid | fluorescent probe |
| ag 1295 | | quinoxaline derivative | geroprotector |
| tyrphostin ag957 | tyrphostin AG957: tyrosine kinase blocker; structure given in first source | aromatic amine | |
| amlexanox | amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
amlexanox: SRA-A antagonist;structure given in first source | monocarboxylic acid;
pyridochromene | anti-allergic agent;
anti-ulcer drug;
non-steroidal anti-inflammatory drug |
| azinphosmethyl | azinphos-methyl : A member of the class of benzotriazines that is 1,2,3-benzotriazine substituted by an oxo group at position 4 and a [(dimethoxyphosphorothioyl)sulfanyl]methyl group at position 3.
Azinphosmethyl: An organothiophosphorus cholinesterase inhibitor. It has been used as an acaricide and as an insecticide. | benzotriazines;
organic thiophosphate;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| bithionol | bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations. | aryl sulfide;
bridged diphenyl antifungal drug;
bridged diphenyl fungicide;
dichlorobenzene;
organochlorine pesticide;
polyphenol | antifungal agrochemical;
antiplatyhelmintic drug |
| carbazilquinone | Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients. | organic molecular entity | |
| danthron | chrysazin : A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8.
danthron: structure | dihydroxyanthraquinone | apoptosis inducer;
plant metabolite |
| diclofenac | diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. | amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound | antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic |
| diflunisal | diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN. | monohydroxybenzoic acid;
organofluorine compound | non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| emodin | emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies. | trihydroxyanthraquinone | antineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor |
| flufenamic acid | flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16) | aromatic amino acid;
organofluorine compound | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| gemfibrozil | | aromatic ether | antilipemic drug |
| meclofenamic acid | meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis. | aminobenzoic acid;
organochlorine compound;
secondary amino compound | analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug |
| mitoxantrone | mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Mitoxantrone: An anthracenedione-derived antineoplastic agent. | dihydroxyanthraquinone | analgesic;
antineoplastic agent |
| niflumic acid | Niflumic Acid: An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. | aromatic carboxylic acid;
pyridines | |
| masoprocol | nordihydroguaretic acid: antioxidant compound found in the creosote bush (Larrea tridentata) | catechols;
lignan;
tetrol | antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite |
| phloretin | | dihydrochalcones | antineoplastic agent;
plant metabolite |
| pomiferin | pomiferin: structure in first source | isoflavanones | |
| ppm 18 | | naphthoquinone | |
| 1,2,5,8-tetrahydroxy anthraquinone | 1,2,5,8-tetrahydroxy anthraquinone: structure in first source
quinalizarin : A tetrahydroxyanthraquinone having the four hydroxy groups at the 1-, 2-, 5- and 8-positions. | tetrahydroxyanthraquinone | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| aurin | aurin: structure | diarylmethane | |
| sulfaquinoxaline | Sulfaquinoxaline: An antiprotozoal agent used to combat coccidial infections of swine, cattle, fowl, and other veterinary animals. Also used in controlling outbreaks of fowl typhoid and fowl cholera and in treatment of infectious enteritis. | benzenes;
sulfonamide | |
| triclosan | | aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols | antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic |
| trifluoperazine | | N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines | antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug |
| trioxsalen | antipsoriatic : A drug used to treat psoriasis.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo. | psoralens | dermatologic drug;
photosensitizing agent |
| thyroxine | thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. | 2-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine;
thyroxine zwitterion | antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone |
| triiodothyronine | 3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine | human metabolite;
mouse metabolite;
thyroid hormone |
| methylene blue | methylene blue : An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.
Methylene Blue: A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN. | organic chloride salt | acid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer |
| alizarin | | dihydroxyanthraquinone | chromophore;
dye;
plant metabolite |
| chlorquinaldol | chlorquinaldol : A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections.
Chlorquinaldol: Local anti-infective agent used for skin, gastrointestinal, and vaginal infections with fungi, protozoa, and certain bacteria. In animals, it causes central nervous system damage and is not administered parenterally. It is also used as antiseptic, fungistat, or deodorant. | monohydroxyquinoline;
organochlorine compound | antibacterial drug;
antiprotozoal drug;
antiseptic drug |
| purpurin | purpurin : A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.
purpurin: from Rubiaceae plants; structure in first source | trihydroxyanthraquinone | biological pigment;
histological dye;
plant metabolite |
| 1,4-dihydroxyanthraquinone | 1,4-dihydroxyanthraquinone: structure given in first source
quinizarin : A dihydroxyanthraquinone having the two hydroxy substituents at the 1- and 4-positions; formally derived from anthraquinone by replacement of two hydrogen atoms by hydroxy groups | dihydroxyanthraquinone | dye |
| 1-naphthylamine-5-sulfonic acid | 1-naphthylamine-5-sulfonic acid: fluorophore used for fluorescent nucleotide substrates | naphthalenesulfonic acid | |
| 1-phenylazo-2-naphthylamine | | | |
| 1-(2-pyridylazo)-2-naphthol | | | |
| salicylanilide | salicylanilide : An amide of salicylic acid and of aniline; it is therefore both a salicylamide and an anilide.
salicylanilide: RN given refers to parent cpd | benzanilide fungicide;
salicylamides;
salicylanilides | |
| isatin | tribulin: endogenous MONOAMINE OXIDASE inhibitory activity extractable into ethyl acetate found in brain and many mammalian tissues and fluids; ISATIN is a major component; produced in excess following alcohol withdrawal; | indoledione | EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| pyronine | pyronin Y : An organic chloride salt having 6-(dimethylamino)-N,N-dimethyl-3H-xanthen-3-iminium as the cation. Used with methyl green to selectively demonstrate RNA (red) in contrast to DNA (green) with the Unna-Pappenheim method.
Pyronine: Xanthene dye used as a bacterial and biological stain. Synonyms: Pyronin; Pyronine G; Pyronine Y. Use also for Pyronine B. which is diethyl-rather than dimethylamino-. | iminium salt;
organic chloride salt | histological dye |
| diphenyl | diphenyl: RN given refers to unlabeled cpd; structure | aromatic fungicide;
benzenes;
biphenyls | antifungal agrochemical;
antimicrobial food preservative |
| fentichlor | fentichlor: structure
fenticlor : An aryl sulfide having two 5-chloro-2-hydroxyphenyl groups attached to sulfur; an antiinfective drug mostly used in veterinary medicine. | aryl sulfide;
bridged diphenyl antifungal drug;
monochlorobenzenes;
polyphenol | antiinfective agent;
drug allergen |
| triclocarban | triclocarban : A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
triclocarban: bacteriostat; antiseptic in soaps & other cleansing solns; germicide; structure | dichlorobenzene;
monochlorobenzenes;
phenylureas | antimicrobial agent;
antiseptic drug;
disinfectant;
environmental contaminant;
xenobiotic |
| anthrarufin | 1,5-dihydroxyanthraquinone: used in ferric ion sensing as an inclusion complex with beta-cyclodextrin; structure in first source
anthrarufin : A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 5. | dihydroxyanthraquinone | |
| 2,4-dihydroxybenzophenone | 2,4-dihydroxybenzophenone: structure in first source | benzophenones | |
| dextrothyroxine | D-thyroxine : The D-enantiomer of thyroxine.
Dextrothyroxine: The dextrorotary isomer of the synthetic THYROXINE. | D-tyrosine derivative;
thyroxine | |
| sterogenol | cetylpyridinium bromide : A pyridinium salt that has N-hexadecylpyridinium as the cation and bromide as the anion.
hexadecylpyridinium bromide: structure in first source | bromide salt;
pyridinium salt | antiseptic drug;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
surfactant |
| 5H-dibenzo[b,f]azepine | 5H-dibenzo[b,f]azepine : A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. | dibenzoazepine;
mancude organic heterotricyclic parent | marine xenobiotic metabolite |
| rhein | | dihydroxyanthraquinone | |
| aloe emodin | Aloe emodin : A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe.
aloe emodin: structure distinct from emodin; this does not mean emodin from aloe | aromatic primary alcohol;
dihydroxyanthraquinone | antineoplastic agent;
plant metabolite |
| chrysophanic acid | chrysophanic acid: RN given refers to parent cpd; structure in Merck, 9th ed, #2260
chrysophanol : A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. | dihydroxyanthraquinone | anti-inflammatory agent;
antiviral agent;
plant metabolite |
| physcione | physcion : A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources.
physcione: structure | dihydroxyanthraquinone | anti-inflammatory agent;
antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
hepatoprotective agent;
metabolite |
| dibromsalicil | dibromsalicil: brominated salicyclic acid deriv; antiplaque antiseptic | | |
| nitrophenide | nitrophenide: Structure in first source | | |
| guaiacol carbonate | | methoxybenzenes | |
| diphenylamine | diphenylamine : An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union.
Diphenylamine: In humans it may be irritating to mucous membranes. Methemoglobinemia has been produced experimentally. In veterinary use, it is one of active ingredients in topical agents for prevention and treatment of screwworm infestation. An indicator in tests for nitrate poisoning. | aromatic amine;
bridged diphenyl fungicide;
secondary amino compound | antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger |
| 2,4,6-triiodophenol | | | |
| c 137 | C 137: RN given refers to parent cpd | | |
| n-methylisatin | N-methylisatin: structure given in first source | | |
| 7-hydroxychlorpromazine | 7-hydroxychlorpromazine: RN given refers to parent cpd | phenothiazines | |
| fluorenone oxime | | | |
| mofebutazone | mofebutazone : A pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain.
mofebutazone: RN given refers to parent cpd; structure | pyrazolidines | non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| 2-methoxy-1,4-naphthoquinone | 2-methoxy-1,4-naphthoquinone : A naphthoquinone that is naphthalene-1,4-dione substituted by a methoxy group at position 2. It has been isolated from the roots of Rubia yunnanensis.
2-methoxy-1,4-naphthoquinone: isolated from Swertia calycina; structure in first source | 1,4-naphthoquinones;
enol ether | antimicrobial agent;
metabolite;
plant metabolite |
| 1,3,5-triglycidyl-s-triazinetrione | | | |
| 1,2-benzisothiazoline-3-one | 1,2-benzisothiazoline-3-one: a preservative in water-based solutions such as paints, cutting fluids, printing inks, cleaning agents, polyvinyl chloride gloves, etc.
benzo[d]isothiazol-3-one : An organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion. | organic heterobicyclic compound;
organonitrogen heterocyclic compound | disinfectant;
drug allergen;
environmental contaminant;
platelet aggregation inhibitor;
sensitiser;
xenobiotic |
| hydroxyphenytoin | 4-hydroxyphenytoin : A imidazolidine-2,4-dione that consists of hydantoin bearing phenyl and 4-hydroxyphenyl substituents at position 5.
hydroxyphenytoin: main metabolite of diphenylhydantoin; reduces Na(+) inhibition at high Na:K ratios; RN given refers to cpd without isomeric designation; structure | imidazolidine-2,4-dione;
phenols | metabolite |
| 2-amino-3-chloro-1,4-naphthoquinone | 2-amino-3-chloro-1,4-naphthoquinone: has antineoplastic activity; structure in first source | 1,4-naphthoquinones | |
| nsc 3852 | 5-nitroso-8-quinolinol: structure in first source | hydroxyquinoline | |
| Bis(2-furanylmethyl) disulfide | | heteroarene | |
| oxycarboxin | oxycarboxin : An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-4,4-dioxo-1,4-oxathiine-3-carboxylic acid. A fungicide for the control of rust diseases on ornamentals, cereals and nursery trees as well as fairy rings on turf.
oxycarboxin: structure | anilide;
anilide fungicide;
organosulfur heterocyclic compound;
oxacycle;
sulfone | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| 5-nitroindazole | | | |
| 3,3',5'-triiodothyronine | | iodothyronine | human metabolite |
| 6,7-Dimethyl-9-(2-acetoxyethyl)isoalloxazine | | flavin | |
| diacerein | diacerein: chelates with bivalent metals; a quinone which possesses redox properties; metabolized to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases; called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase; | anthraquinone | |
| marmesin, (r)-isomer | nodakenetin : A marmesin with R-configuration. | marmesin | plant metabolite;
rat metabolite;
xenobiotic metabolite |
| 3-methyl-2-quinoxalinol | | quinoxaline derivative | |
| clioxanide | clioxanide: structure | | |
| 2,2',6,6'-tetrachlorobiphenyl | 2,2',6,6'-tetrachlorobiphenyl: structure in first source | | |
| 18-crown-6 | 18-crown-6 : A crown ether that is cyclooctadecane in which the carbon atoms at positions 1, 4, 7, 10, 13 and 16 have been replaced by oxygen atoms. | crown ether;
saturated organic heteromonocyclic parent | phase-transfer catalyst |
| n-(cyclohexylthio)phthalimide | N-(cyclohexylthio)phthalimide: water pollutant | | |
| daunorubicin | anthracycline : Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.
daunorubicin : A natural product found in Actinomadura roseola.
Daunorubicin: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS. | aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones | antineoplastic agent;
bacterial metabolite |
| (7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | | anthracycline | |
| N-fluorenylacetamide | | fluorenes | |
| isovelleral | isovelleral: structure given in first source | aldehyde | |
| phenicaberan | | | |
| s-2678 | XI-006: diminishes MDM4 promoter activity; structure in first source | | |
| triclabendazole | | aromatic ether | |
| nsc 330770 | NSC 330770: structure given in first source | | |
| 3-morpholinopropylamine | 3-morpholinopropylamine : A member of the class of morpholines that is morpholine substituted by a 3-aminopropyl group a the N atom. | morpholines;
primary amino compound | |
| 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | | C-nitro compound;
furans | |
| 5-Aminoacenaphthene | | naphthalenes | |
| diacetylfluorescein | | | |
| epigallocatechin gallate | (-)-epigallocatechin 3-gallate : A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
epigallocatechin gallate: a steroid 5alpha-reductase inhibitor and antimutagen in green tea (Camellia sinensis) | flavans;
gallate ester;
polyphenol | antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite |
| 2,2'-dipyridyl disulfide | 2,2'-dipyridyl disulfide: disulfide is an important moiety in this cpd
aldrithiol : A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. | organic disulfide;
pyridines | oxidising agent |
| n,n'-bis(salicyl)hydrazine | N,N'-bis(salicyl)hydrazine: structure in first source | | |
| 9,10-anthraquinone 2-carboxylic acid | 9,10-anthraquinone 2-carboxylic acid: structure in first source | | |
| n-acetylsulfamethoxypyridazine | | | |
| 4,7-phenanthroline | | phenanthroline | |
| dibenzthione | dibenzthione: structure | aromatic amine | |
| harmol | harmol: harmol is oxidized form of alkaloid harmolol; RN given refers to parent cpd; structure | harmala alkaloid | |
| oxiperomide | oxiperomide: dopamine-blocking agent | | |
| 1,2-bis(phenylsulfonyl)ethane | | | |
| norcyclizine | norcyclizine: RN given refers to parent cpd; structure in first source | | |
| 4-Formyl-antipyrine | | pyrazoles;
ring assembly | |
| morphazinamide | morphazinamide: RN given refers to parent cpd; RN in Chemline for mono-HCL: 1473-73-0; structure in Merck Index | morpholines;
pyrazines;
secondary carboxamide | |
| 2,2',2''-terpyridine | 2,2',2''-terpyridine: RN given refers to parent cpd
2,2':6',2''-terpyridine : A tridentate heterocyclic ligand that binds metals at three meridional sites giving two adjacent 5-membered MN2C2 chelate rings. | terpyridines | chelator |
| propipocaine monohydrochloride | | | |
| aceclofenac | | amino acid;
carboxylic ester;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| 9-methoxyellipticine | 9-methoxyellipticine: RN given refers to parent cpd | | |
| 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acid | 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acid: structure given in first source | | |
| coumarin 153 | coumarin 153: structure in first source | 7-aminocoumarins | fluorochrome |
| methyl fluorone black | methyl fluorone black: structure | | |
| 3-aminophenoxazone | 3-aminophenoxazone: also inhibits sulfatase; structure | phenoxazine | |
| 2-phenyl-4,5-dichloro-3-pyridazinone | | | |
| centazolone | centazolone: tranquillosedative drug with action similar to that of chlordiazepoxide; structure in UD 30;55a | | |
| methylene violet | methylene violet: structure given in first source | | |
| 8-hydroxy-2-quinolinecarboxylic acid | | quinolines | |
| 1-ethyl-2-benzo[cd]indolone | | isoindoles | |
| 2-Amino-6-(benzylthio)purine | | thiopurine | |
| 7-bromo-5-phenyl-1,2-dihydro-2h-1,4-benzodiazepin-2-one | 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one: RN given refers to unlabeled parent cpd | | |
| 3,5-di-tert-butyl-1,2-benzoquinone | | | |
| 1-methyl-2-phenylindole | | | |
| 2-methyl-4-nitroquinoline 1-oxide | 2-methyl-4-nitroquinoline 1-oxide: structure | | |
| 8-(4-tolylsulfonylamino)quinoline | 8-(4-tolylsulfonylamino)quinoline: has diabetogenic properties; can be used for fluorometric determination of zinc; structure given in first source | sulfonamide | |
| n,n'-2-phenylenedimaleimide | N,N'-2-phenylenedimaleimide: RN given refers to 2-phenylene-cpd | | |
| 2-butyl-6-(butylamino)-1h-benzo(de)isoquinoline-1,3(2h)-dione | | | |
| 5-bromonicotinic acid | 5-bromonicotinic acid: structure given in first source | | |
| 5-benzyloxytryptamine | | | |
| streptovitacin a | streptovitacin A: structure | | |
| pyridaben | | organochlorine acaricide;
organochlorine insecticide;
pyridazinone | mitochondrial NADH:ubiquinone reductase inhibitor |
| coumarin 7 | coumarin 7: structure in first source | | |
| 1-piperonylpiperazine | 1-piperonylpiperazine: coadministration of above cpd attenuates neurotoxicity of 3,4-methylenedioxymethamphetamine; RN given refers to parent cpd | | |
| osajin | osajin: from Maclura pomifera | isoflavanones | |
| 9,10-phenanthrenequinone monoxime | 9,10-phenanthrenequinone monoxime: selective sensitive reagent for iron in environmental samples | | |
| 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol | 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol : A member of the class of hydroxybiphenyls formed formally by chlorination of biphenyl-4,4'-diol at C-3, -3', -5 and -5'. | dichlorobenzene;
hydroxybiphenyls | |
| 2-nitrobenzimidazole | 2-nitrobenzimidazole: RN given refers to parent cpd | | |
| 1,3-diphenyl-2-propyn-1-one | 1,3-diphenyl-2-propyn-1-one: structure in first source | | |
| 3,3'-Dihydroxyhexestrol | | stilbenoid | |
| wr 158122 | WR 158122: structure | | |
| n-acetylphenylalanyl-phenylalanine | | | |
| difenpiramide | | biphenyls;
monocarboxylic acid amide;
pyridines | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| diphyllin | diphyllin: extract of Cleistanthus collinus (Roxb), a highly poisonous plant; do not confuse with diphyllin or diphylline which is the main heading AMINOPHYLLINE; do not confuse with the theophylline derivative DYPHYLLINE | lignan | |
| karanjin | karanjin: structure given in first source | extended flavonoid | |
| 4-hydroxy-2',4',6'-trichlorobiphenyl | 4-hydroxy-2',4',6'-trichlorobiphenyl: do not confuse with the tetrachlorinated compound, also known as 4-OH-TCB (see 4-OH-TCB (tetra)) | biphenyls;
trichlorobenzene | |
| tanshinone | tanshinone: from root of Salvia miltiorrhiza Bunge; RN given refers to tanshinone I; cardioprotective agent and neuroprotective agent | abietane diterpenoid | anticoronaviral agent |
| pirlindole hydrochloride | | | |
| 3-(1-piperidinyl)-1-(4-propan-2-yloxyphenyl)-1-propanone | | aromatic ketone | |
| 1,3-dimethylbenzimidazoline-2-thione | 1,3-dimethylbenzimidazoline-2-thione: structure given in first source | | |
| glabridin | | hydroxyisoflavans | antiplasmodial drug |
| 3'-deamino-3'-hydroxydaunorubicin | 3'-deamino-3'-hydroxydaunorubicin: structure given in first source | | |
| ly 188544 | LY 188544: RN given refers to cpd without isomeric designation; LY 188545 is the (S)-isomer; LY 188546 is the (R)-isomer; structure given in first source | benzamides | |
| omeprazole magnesium | esomeprazole magnesium : A magnesium salt resulting from the formal reaction of magnesium hydroxide with 2 mol eq. of esomeprazole. An inhibitor of gastric acid secretion, it is used for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome. | benzimidazoles;
sulfoxide | |
| n-(6-methoxy-8-quinolyl)-4-toluenesulfonamide | | | |
| umifenovir | umifenovir: an antiviral agent | indolyl carboxylic acid | |
| 1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanone | | benzodioxoles | |
| 4,5-diphenyl-4-oxazolin-2-one | 4,5-diphenyl-4-oxazolin-2-one: amino group protecting agent in peptide synthesis; structure | | |
| 8-(methylsulfonylamino)quinoline | 8-(methylsulfonylamino)quinoline: has diabetogenic properties; structure given in first source | | |
| 1,4-di(2'-thienyl)-1,4-butadione | 1,4-di(2'-thienyl)-1,4-butadione: structure given in first source | | |
| sch 45752 | | organic heterotricyclic compound;
organooxygen compound | |
| 2-chloroacetoacetanilide | 2-chloroacetoacetanilide: structure in first source | | |
| 2-methyl-4-(phenylimino)naphth(2,3-d)oxazol-9-one | 2-methyl-4-(phenylimino)naphth(2,3-d)oxazol-9-one: structure in first source | | |
| 8-(4-benzenesulfonylamino)quinoline | 8-(4-benzenesulfonylamino)quinoline: has diabetogenic properties; structure given in first source | | |
| dihydroguaiaretic acid | dihydroguaiaretic acid: lignan extracted form Larrea divaricata; inhibitory to beef heart mitochondrial succinoxidase & NADH-oxidase; RN given refers to cpd without isomeric designation | | |
| 3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one | | indoles | |
| 2,4-dinitropyrimidinyl-2-thiophenol | | | |
| enniatin b | enniatin B : An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine units.
enniatins: cyclohexadepsipeptides containing valine, isoleucine & valeric acid from Fusarian; form complexes with cations & cellular membranes; there are at least three different enniatins H, B & C; minor descriptor (76-86); on-line & INDEX MEDICUS search PEPTIDES, CYCLIC (76-86); see also record for enniatin D, E, F | enniatin | antimicrobial agent |
| 2-phenyl-1,2-benzisothiazol-3-(2h)-one | 2-phenyl-1,2-benzisothiazol-3-(2H)-one: structure given in first source; sulfur analog of ebselen | | |
| 4-butyl-4-(hydroxymethyl)-1,2-diphenylpyrazolidine-3,5-dione | | benzenes | |
| 2-(1,1,2,2-tetrafluoroethyl)benzimidazole | | | |
| 4-methoxy-1-vinylcarboline | | | |
| 2-[4-(4-methoxyphenyl)-1-piperazinyl]pyrimidine | | piperazines | |
| Phthalyltyrosine | | tyrosine derivative | |
| 3-nitrotyrosine | 3-nitrotyrosine : A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring.
3-nitrotyrosine: RN given refers to parent cpd without isomeric designation | 2-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid | |
| benzatropine methanesulfonate | | | |
| 1',2'-dihydrorotenone | 1',2'-dihydrorotenone: RN given refers to (2R-(2alpha,6aalpha,12aalpha))-isomer; structure given in first source | | |
| 2-methyl-3-(phenylthio)pyrazine | | aryl sulfide | |
| gant58 | GANT58: inhibits hedgehog signalling; structure in first source | pyridines | |
| coronopilin | coronopilin: isolated from Ambrosia arborescens | sesquiterpene lactone | |
| 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one | 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one: has antineoplastic activity; structure in first source | | |
| 2-chloro-3-(4-methylanilino)naphthalene-1,4-dione | | 1,4-naphthoquinones | |
| 4-amino-1,2-dithiolane-4-carboxylic acid | 4-amino-1,2-dithiolane-4-carboxylic acid: structure in first source | | |
| papaverinol | papaverinol: degradation product of papaverine | | |
| dimethyl 2-(2-nitrobenzylidene)malonate | dimethyl 2-(2-nitrobenzylidene)malonate: inhibits TLR4 signaling; structure in first source | | |
| nsc 154020 | | N-glycosyl compound | |
| 4-chloro-1H-indazol-3-amine | | indazoles | |
| nsc228155 | | | |
| 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one | 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one: structure in first source | cyclic ketone;
quinuclidines | |
| Cadabicilone | | sesquiterpene lactone | |
| mitonafide | | | |
| pinafide | pinafide: structure | | |
| rocaglamide | rocaglamide : An organic heterotricyclic compound that is 2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan substituted by hydroxy groups at positions 1 and 8b, methoxy groups at positions 6 and 8, a 4-methoxyphenyl group at position 3a, a phenyl group at position 3 and a N,N-dimethylcarbamoyl group at position 1. Isolated from Aglaia odorata and Aglaia duperreana, it exhibits antineoplastic activity.
rocaglamide: RN refers to (1alpha,2alpha,3beta,3abeta,8bbeta)-isomer; isolated from stems of Aglaia elliptifolia; structure given in first source | monocarboxylic acid amide;
monomethoxybenzene;
organic heterotricyclic compound | antileishmanial agent;
antineoplastic agent;
metabolite |
| 2-[(4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethylcyclohexane-1,3-dione | | beta-diketone | |
| 6-dimethylaminopurine arabinoside | | | |
| nsc606985 | | | |
| 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone | 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone: structure in first source | | |
| nsc668394 | | | |
| nsc 680410 | NSC 680410: a bcr/abl kinase inhibitor; structure in first source | | |
| nsc681152 | | | |
| 5,7-dimethoxy-4-methyl-1-benzopyran-2-one | | coumarins | |
| nsc689857 | | | |
| nsc697923 | | | |
| 4-(4-chlorophenyl)-1-methyl-2-(methylthio)-6-oxo-5-pyrimidinecarbonitrile | | pyrimidines | |
| nsc-134754 | | | |
| N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide | | diarylmethane | |
| Destruxin B | | cyclodepsipeptide | |
| macbecin ii | macbecin II: from Norcardia sp. No. C-14919; belongs to ansamycin group of antibiotics; structure in second source | | |
| resveratrol | trans-resveratrol : A resveratrol in which the double bond has E configuration. | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger |
| 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione | | pyrimidotriazine | |
| 6,8-diprenylgenistein | 5,7,4'-trihydroxy-6,8-diprenylisoflavone : A member of the class of 7-hydroxyisoflavones that is genistein substituted by prenyl groups at positions 6 and 8. It has been isolated from Derris scandens and Glycyrrhiza uralensis.
6,8-diprenylgenistein: a lysoPAF acetyltransferase inhibitor isolated from licorice root; structure in first source | 7-hydroxyisoflavones | antibacterial agent;
plant metabolite |
| 9,14-Dimethyl-5-methylidene-3,13-dioxatetracyclo[8.4.0.02,6.012,14]tetradec-9-ene-4,11-dione | | germacranolide | |
| 2-sulfanylidene-1,3-dithiole-4,5-dicarboxylic acid dimethyl ester | | heteroarene | |
| 2-chloro-N-(5-methyl-3-isoxazolyl)acetamide | | aromatic amide | |
| 2-(2-phenoxyethylsulfonyl)-1H-benzimidazole | | benzimidazoles;
sulfoxide | |
| LSM-22807 | | aromatic ether | |
| tolfenamic acid | tolfenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity.
tolfenamic acid: structure | aminobenzoic acid;
organochlorine compound;
secondary amino compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| 2-(1-piperazinyl)-4-amino-6,7-dimethoxyquinazoline | 2-(1-piperazinyl)-4-amino-6,7-dimethoxyquinazoline: prazosin metabolite; RN given refers to parent cpd | | |
| 2-chlorothioxanthen-9-one | 2-chlorothioxanthen-9-one: chlorprothixene degradation product | | |
| xanthohumol | xanthohumol : A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells.
xanthohumol: from hop plant, Humulus lupulus | aromatic ether;
chalcones;
polyphenol | anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite |
| dibenzylidene acetone | dibenzylidene acetone: structure in first source | | |
| cgp 60474 | | substituted aniline | |
| 2-(4-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide | | benzoxazole | |
| 4-(4-fluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid 1,3-benzodioxol-5-ylmethyl ester | | benzodioxoles | |
| 7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one | | benzodiazepine | |
| 3-methyl-4-(7-methyl-2-indolizinyl)-1,2,5-oxadiazole | | indolizines | |
| 3-[[1,3-benzodioxol-5-ylmethyl-[(1-cyclopentyl-5-tetrazolyl)methyl]amino]methyl]-6-ethyl-1H-quinolin-2-one | | quinolines | |
| 1-(3-chloro-4-methoxyphenyl)sulfonyl-N-(3-pyridinyl)-3-piperidinecarboxamide | | sulfonamide | |
| 2-(4-bromophenyl)-5-(2-methylphenyl)-1,3,4-oxadiazole | | organobromine compound | |
| 5-(4-propylcyclohexyl)-3-(3-pyridinyl)-1,2,4-oxadiazole | | pyridines | |
| N-[2-[1,3-benzodioxol-5-yl-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]amino]-2-oxoethyl]-2-furancarboxamide | | peptide | |
| N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamide | | aromatic ether | |
| N-tert-butyl-N-[2-(tert-butylamino)-2-oxoethyl]-3-(3,4-dihydro-2H-quinolin-1-yl)propanamide | | peptide | |
| 4-[4-[(5,6-dimethyl-1-benzimidazolyl)sulfonyl]phenyl]sulfonylmorpholine | | sulfonamide | |
| 2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide | | aromatic amide | |
| N-[1-[2-(2-chlorophenoxy)ethyl]-2-benzimidazolyl]acetamide | | benzimidazoles | |
| N-[4-[(tert-butylamino)-oxomethyl]phenyl]-2,3-dihydro-1,4-benzodioxin-3-carboxamide | | amidobenzoic acid | |
| 3-(2,5-dimethyl-1-pyrrolyl)-4-methylaniline | | pyrroles | |
| 4-[[[[8-[(1-tert-butyl-5-tetrazolyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]amino]-oxomethyl]amino]benzoic acid ethyl ester | | benzoate ester | |
| N-(4-methylphenyl)-2-(3-oxo-5,6-dihydroimidazo[2,1-b]thiazol-2-yl)acetamide | | anilide | |
| 3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-one | | quinolines | |
| 1-[4-(2-methoxyphenyl)-1-piperazinyl]-2-[[5-(2-methyl-3-furanyl)-1,3,4-oxadiazol-2-yl]thio]ethanone | | piperazines | |
| N-[3-(dimethylamino)-2,2-dimethylpropyl]-1-[(2-hydroxyphenyl)methyl]-4-piperidinecarboxamide | | piperidines | |
| 2-methoxy-N-methyl-N-[5-(5-methyl-2-pyrazinyl)-1,3,4-thiadiazol-2-yl]acetamide | | pyrazines | |
| 3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-6-methyl-1H-quinolin-2-one | | quinolines | |
| 2-[2-[[2-[[1-(4-methoxyphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester | | pyrazoles;
ring assembly | |
| [4-[5-tert-butyl-3-[(2-chlorophenyl)methyl]-7-triazolo[4,5-d]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanone | | N-arylpiperazine | |
| N-[2-[2-[2-(4-methoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-furancarboxamide | | aromatic amide;
furans | |
| 9-oxo-N-(3-pyridinylmethyl)-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinoline-8-carboxamide | | aromatic amide;
quinolines | |
| (6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-[5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]methanone | | quinolines | |
| 5-[(2-fluoroanilino)methyl]-8-quinolinol | | hydroxyquinoline | |
| 4-[[4-(1,3-benzothiazol-2-yl)-1-piperazinyl]-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-2-methoxyphenol | | N-arylpiperazine | |
| N-[4-(4-fluorophenyl)-2-thiazolyl]-2-[(4-methylphenyl)sulfonylamino]benzamide | | sulfonamide | |
| 1-cyclohexyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-amine | | pyrroloquinoline | |
| 2'-amino-5',6'-dimethoxy-1'-spiro[cyclopentane-1,3'-indene]carbonitrile | | indene | |
| 3-(4-butyl-3,5-dimethyl-1-pyrazolyl)-5-methyl-[1,2,4]triazino[5,6-b]indole | | triazinoindole | |
| 6-amino-4-(5-bromo-2-thiophenyl)-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | | pyranopyrazole;
thiophenes | |
| 5-bromo-3-[[2-(4-cyclohexyl-1-piperazinyl)-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl ester | | indolyl carboxylic acid | |
| 5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide | | benzothiazine | |
| 3-(5-cycloheptylidene-4-oxo-2-sulfanylidene-3-thiazolidinyl)propanoic acid | | thiazolidines;
thiocarbonyl compound | |
| 1-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea | | thiadiazoles;
ureas | |
| 1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea | | thiadiazoles;
ureas | |
| 2-(2-oxo-3H-1,4-benzoxazin-4-yl)acetic acid [2-(3-bromo-4-methoxyphenyl)-2-oxoethyl] ester | | alpha-amino acid ester | |
| 2-[[5-cyano-2-(3,4-dimethoxyphenyl)-4-oxo-2,3-dihydro-1,3-thiazin-6-yl]thio]acetic acid ethyl ester | | dimethoxybenzene | |
| 1-(4-chlorophenyl)-N-(1-methoxypropan-2-yl)-4-pyrazolo[3,4-d]pyrimidinamine | | pyrazoles;
ring assembly | |
| 3-benzamido-5-bromo-2-benzofurancarboxylic acid methyl ester | | benzofurans | |
| 5-(2,4-dimethoxyphenyl)-7-(3,4-dimethoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine | | dimethoxybenzene | |
| 4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl ester | | pyrimidinecarboxylic acid | |
| N-[3-(2-furanylmethylamino)-2-quinoxalinyl]-3-methylbenzenesulfonamide | | quinoxaline derivative | |
| 3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione | | aromatic ketone | |
| N-[2-[5-[(2,4-dichlorophenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamic acid tert-butyl ester | | dichlorobenzene | |
| 2-[(2,5-dimethyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinyl)thio]acetonitrile | | pyrazoles;
ring assembly | |
| 6-(3,4,5-triethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | | aromatic ether;
triazolothiadiazole | |
| 7-methyl-3-(3-methylbutylamino)-1-(1-pyrrolidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile | | naphthyridine derivative | |
| N-(4,6-dimethyl-2-pyrimidinyl)-1,3-bis(phenylmethyl)-2,4-dihydro-1,3,5-triazin-6-amine | | aralkylamine | |
| 7-(3,4-dimethoxyphenyl)-4-methyl-2-[4-(phenylmethyl)-1-piperazinyl]-7,8-dihydro-6H-quinazolin-5-one | | N-arylpiperazine | |
| N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)pentanamide | | benzimidazoles | |
| LSM-20899 | | pyranopyridine | |
| 3,4,7-trimethyl-5-(3-oxobutan-2-yloxy)-1-benzopyran-2-one | | coumarins | |
| caffeic acid | trans-caffeic acid : The trans-isomer of caffeic acid. | caffeic acid | geroprotector;
mouse metabolite |
| methyl caffeate | methyl caffeate : An alkyl caffeate ester formed by the formal condensation of caffeic acid with methyl alcohol.
methyl caffeate: from plant Gaillardia pulchella | alkyl caffeate ester;
methyl ester | |
| 4-(3-amino-2-imidazo[1,2-a]pyridinyl)-2-methoxyphenol | | imidazoles | |
| N-(2-furanylmethyl)-4-(2-methyl-3-imidazo[1,2-a]pyridinyl)-2-thiazolamine | | imidazopyridine | |
| 2,6-dimethyl-N-(4-methylphenyl)-4-quinolinamine | | aminoquinoline | |
| 2-[(4-chloro-2-methylphenoxy)methyl]imidazo[1,2-a]pyrimidine | | imidazopyrimidine | |
| 1-(2,4-dimethylphenyl)-4-(1-piperidinylsulfonyl)piperazine | | piperazines | |
| 4-chloro-1-methyl-3-nitro-2-quinolinone | | nitro compound;
quinolines | |
| N1-(6-bromo-4-quinazolinyl)-N4,N4-dimethylbenzene-1,4-diamine | | quinazolines | |
| 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-hydroxy-3-pyrazolecarboxylic acid ethyl ester | | benzodioxine | |
| 2-mercaptobenzimidazole | 2-mercaptobenzimidazole: purine synthesis antimetabolite; RN given refers to parent cpd | | |
| N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-oxo-3-quinazolinyl)acetamide | | quinazolines | |
| 2-methoxy-6-[[(1-methyl-2-benzimidazolyl)amino]methyl]phenol | | methoxybenzenes;
phenols | |
| 2-(3-oxo-2-phenyl-1H-pyrazol-5-yl)acetic acid methyl ester | | pyrazoles;
ring assembly | |
| 4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile | | benzenes;
nitrile | |
| bemethyl | | | |
| 5-cyano-2-methyl-6-sulfanylidene-1H-pyridine-3-carboxylic acid ethyl ester | | aromatic carboxylic acid;
pyridines | |
| 1-cyclohexyl-3-[[oxo(thiophen-2-yl)methyl]amino]thiourea | | aromatic amide;
thiophenes | |
| 4,5-dimethylaminobenzylidene-2-thiobarbituric acid | | | |
| 1-(4-chlorophenyl)-3-(4-sulfamoylphenyl)urea | | sulfonamide | |
| N-[4-(diethylamino)phenyl]-N'-phenylurea | | dialkylarylamine;
tertiary amino compound | |
| N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl ester | | aromatic ether | |
| 1-benzoyl-4-phenyl-3-thiosemicarbazide | 1-benzoyl-4-phenyl-3-thiosemicarbazide: structure in first source | | |
| 2,4-Dimethyl-1,3-thiazole-5-carboxylic acid | | aromatic carboxylic acid;
thiazoles | |
| 2-(4-hydroxyanilino)-1,4-naphthoquinone | 2-(4-hydroxyanilino)-1,4-naphthoquinone: structure in first source | | |
| 1-(3,5-dichlorophenyl)-3-phenylurea | | ureas | |
| 3-(2,4-dioxo-6-methyl-5-pyrimidinyl)acrylic acid | 3-(2,4-dioxo-6-methyl-5-pyrimidinyl)acrylic acid: RN refers to (E)-isomer; structure in first source | | |
| 5,6-dimethyl-2-[2-(1-pyrrolidinyl)ethylthio]-1H-benzimidazole | | benzimidazoles | |
| nsc185058 | NSC185058: an ATG4B antagonist | | |
| 2-fluoro-N-phenacylbenzamide | | aromatic ketone | |
| 1-(3-pyridinylmethyl)-3-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]urea | | benzodioxoles | |
| 3-(2,3-dimethyl-1H-indol-5-yl)-4-methyl-1H-1,2,4-triazole-5-thione | | methylindole | |
| 2-(1,3-benzothiazol-2-ylmethoxy)phenol | | benzothiazoles | |
| 3-(8-methyl-2-imidazo[1,2-a]pyridinyl)-1-benzopyran-2-one | | coumarins | |
| 2-[[2-(5,6-dimethyl-1-benzimidazolyl)-1-oxoethyl]amino]benzoic acid methyl ester | | amidobenzoic acid | |
| 3-chloro-1-(3,4-dichlorophenyl)-4-(dimethylamino)pyrrole-2,5-dione | | maleimides | |
| 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | | aromatic compound | |
| 2-(dichloromethyl)-4-(ethylthio)-6-phenyl-1,3,5-triazine | | 1,3,5-triazines;
organic sulfide | |
| 1-spiro[2,4-dihydroisoquinoline-3,1'-cyclohexane]thione | | isoquinolines | |
| 4-(2-naphthalenylmethyl)-1-piperazinecarboxylic acid ethyl ester | | naphthalenes | |
| 4-tert-butyl-N-[2-(2-methoxyphenyl)ethyl]-1-cyclohexanamine | | primary amine | |
| N-(1-acetyl-2-chloro-3-indolyl)-2-chloroacetamide | | indoles | |
| N-[3-[[2-furanyl(oxo)methyl]amino]phenyl]-5-nitro-2-furancarboxamide | | aromatic amide;
furans | |
| 3-amino-4-(4-chlorophenyl)-6-cyclopropyl-2-thieno[2,3-b]pyridinecarbonitrile | | phenylpyridine | |
| N-[4-(1-azepanyl)phenyl]-2-chloroacetamide | | anilide | |
| [4-(2-methylphenyl)-1-piperazinyl]-(4-nitrophenyl)methanethione | | piperazines | |
| 4-chloro-1-ethyl-3-nitro-2-quinolinone | | nitro compound;
quinolines | |
| 3-(3-nitrophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | | triazoles | |
| 2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde | | arenecarbaldehyde | |
| 3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide | | pyrazoles;
ring assembly | |
| 9-oxo-3-fluorenecarboxylic acid (phenylmethyl) ester | | fluorenes | |
| 1-(4-bromophenyl)-3-(2-phenylethyl)thiourea | | thioureas | |
| N-(1,3-benzothiazol-2-yl)-2-cyclohexylacetamide | | benzothiazoles | |
| 5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | | oxadiazole;
ring assembly | |
| N-(4-fluorophenyl)-3,4-dihydro-1H-isoquinoline-2-carboxamide | | isoquinolines | |
| 3-prop-2-enyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 8-methyl-1,5-dihydropyrimido[5,4-b]indole-4-thione | | pyrimido-indole | |
| 7,8-dimethoxy-1,5-dimethyl-3-phenylpyrazolo[3,4-c]isoquinoline | | pyrazoles;
ring assembly | |
| N-methyl-2-(4-methylphenyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine | N-methyl-2-(4-methylphenyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine : A member of the class of quinazolines that is quinazoline which is substituted by a 4-methylphenyl group and a methyl(1-methylpiperidin-4-yl)nitrilo group at positions 2 and 4, respectively. | piperidines;
quinazolines;
tertiary amino compound;
toluenes | |
| N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide | | biphenyls | |
| N-(6-methyl-2-pyridinyl)-5-nitro-2-furancarboxamide | | C-nitro compound;
furans | |
| 1-(3-chlorophenyl)-3-(phenylmethyl)thiourea | | thioureas | |
| N-(3-phenyl-1,3-benzothiazol-2-ylidene)-2-propenamide | | benzothiazoles | |
| 2-[[4-(1-pyrrolidinylsulfonyl)phenyl]hydrazinylidene]propanedinitrile | | sulfonamide | |
| N-[3,4-dihydro-2H-quinolin-1-yl(sulfanylidene)methyl]-2-(3-methylphenoxy)acetamide | | quinolines | |
| N-[(2,3-dimethoxyphenyl)methyl]-4-(4-methyl-1-piperidinyl)aniline | | aromatic amine | |
| 4-phenyl-N-(2-pyridinyl)butanamide | | aromatic amide | |
| 3-[[(3-chloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid | | benzamides | |
| N-(4-methyl-2-pyridinyl)-5-nitro-2-furancarboxamide | | C-nitro compound;
furans | |
| 2-methoxy-3-methyl-N-[4-(4-morpholinylmethyl)phenyl]benzamide | | benzamides | |
| 2-chloro-N-[5-ethyl-3-[(4-methylphenyl)-oxomethyl]-2-thiophenyl]acetamide | | aromatic ketone | |
| 1-(2-methyl-6-propan-2-ylphenyl)-5-phenyltetrazole | | tetrazoles | |
| 5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide | | aromatic amide;
heteroarene | |
| N-(2-cyano-1-cyclopentenyl)-1-ethyl-3-pyrazolecarboxamide | | aromatic amide;
heteroarene | |
| N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)aniline | | aromatic amine | |
| N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamide | | thiazoles | |
| 2-(2-methylphenoxy)-N-[2-(methylthio)phenyl]acetamide | | anilide | |
| 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione | | pyrimidotriazine | |
| 2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid methyl ester | | pyrroles | |
| 2-(4-chlorophenyl)-4-propan-2-yloxyquinazoline | | quinazolines | |
| N2-(4-fluorophenyl)-6-(3-methyl-2-benzofuranyl)-1,3,5-triazine-2,4-diamine | | benzofurans | |
| 1-(4-methylphenyl)sulfonyl-4-phenyl-3-pyrazolamine | | pyrazoles;
ring assembly | |
| 5-hydroxy-7-(4-nitrophenyl)-1,3-benzoxathiol-2-one | | C-nitro compound | |
| 3-[4-(2-methylphenyl)-5-sulfanylidene-1H-1,2,4-triazol-3-yl]-1H-pyridazin-6-one | | triazoles | |
| 1-methyl-5-(1-naphthalenyloxy)-4-nitroimidazole | | aromatic ether | |
| 3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester | | aromatic ketone | |
| N-(1,3-benzodioxol-5-yl)-4-(2-furanylmethyl)-1-piperazinecarbothioamide | | benzodioxoles | |
| 1-(4-acetylphenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea | | aromatic ketone | |
| 6-hydroxy-2-(4-nitrophenyl)-3,1-benzoxazin-4-one | | benzoxazine | |
| 3-chloro-4-[(1-ethyl-2-benzimidazolyl)thio]aniline | | aryl sulfide | |
| (2,3-dimethoxyphenyl)-(1-pyrrolidinyl)methanethione | | dimethoxybenzene | |
| 1-(1-pyrrolidinyl)-2-(8-quinolinylthio)ethanone | | quinolines | |
| 1-[tert-butyl-[(3,5-dimethylphenyl)-oxomethyl]amino]-3-(4-chlorophenyl)urea | | ureas | |
| 5-(4-bromophenyl)-N-[[(2-propyl-5-tetrazolyl)amino]-sulfanylidenemethyl]-2-furancarboxamide | | furoic acid | |
| N-[3-chloro-2-(4-morpholinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | | aromatic amide | |
| 6-chloro-4-phenyl-3-(1-phenyl-5-tetrazolyl)quinoline | | quinolines | |
| N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | | thioureas | |
| 1-(2,1,3-benzothiadiazol-5-yl)-3-[4-(4-morpholinyl)phenyl]urea | | morpholines | |
| N-(1-tert-butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide | | benzimidazoles | |
| 2-[[cyclohexyl(oxo)methyl]amino]-1,3-benzothiazole-6-carboxylic acid methyl ester | | benzothiazoles | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamide | | aromatic amide;
thiophenes | |
| N-[5-(1,3-benzothiazol-2-yl)-2-chlorophenyl]-1,3-benzodioxole-5-carboxamide | | aromatic amide | |
| 6-[[(4,6-dimethyl-2-pyrimidinyl)thio]methyl]-N2-(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine | | methoxybenzenes;
substituted aniline | |
| N-[4-[(3,4-dimethoxyphenyl)sulfamoyl]phenyl]acetamide | | sulfonamide | |
| N'-methyl-N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-N'-(phenylmethyl)butanediamide | | imidazoles | |
| N2,N7-bis(2,5-dimethylphenyl)-9H-fluorene-2,7-disulfonamide | | fluorenes | |
| LSM-16285 | | bipyridines | |
| 5-nitro-N-[4-(2-oxazolo[4,5-b]pyridinyl)phenyl]-2-furancarboxamide | | aromatic amide;
furans | |
| 2-(3,4-dimethoxyphenyl)-8-methoxy-4,4-dimethyl-5H-isothiazolo[5,4-c]quinoline-1-thione | | dimethoxybenzene | |
| [4-(diphenylmethyl)-1-piperazinyl]-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone | | diarylmethane | |
| N-(4-Methoxybenzoyl)-2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanehydrazonic acid | | triazoles | |
| 3-[[2-[[6-fluoro-2-(4-fluorophenyl)-4-quinazolinyl]thio]-1-oxoethyl]amino]benzoic acid | | amidobenzoic acid | |
| 4,5-dimethoxy-2-[[1-oxo-2-[(3,5,8-trimethyl-2-quinolinyl)thio]ethyl]amino]benzoic acid | | amidobenzoic acid | |
| 3-pyridinecarboxylic acid [2-(2-furanyl)-4-oxo-1-benzopyran-3-yl] ester | | chromones | |
| 2-(4-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-quinazolinamine | | morpholines | |
| 2-(4-methylsulfonyl-2-nitrophenyl)sulfinylacetic acid (phenylmethyl) ester | | carboxylic ester | |
| 5-(3,4-dimethoxyphenyl)-2-(4-methylphenyl)-4-thieno[2,3-d][1,3]oxazinone | | dimethoxybenzene | |
| 9-(dimethylamino)-3-(4-methoxyphenyl)-4-pyrido[1,2]thieno[3,4-d]pyrimidinone | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 5-(4-fluorophenyl)sulfonyl-1-(2-methylpropyl)-4-nitro-2-propan-2-ylimidazole | | imidazoles | |
| N-[(4-ethylanilino)-sulfanylidenemethyl]-3-methylbutanamide | | thioureas | |
| N-(5-chloro-2-pyridinyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)acetamide | | aromatic amide | |
| 5-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-isoxazolecarboxamide | | aromatic amide;
heteroarene | |
| 5-bromo-N-[2-(4-chlorophenyl)ethyl]-2-thiophenecarboxamide | | aromatic amide;
thiophenes | |
| N-[2-methoxy-5-(2-oxo-1-benzopyran-3-yl)phenyl]-5-nitro-2-furancarboxamide | | isoflavonoid | |
| 8-methoxy-6-nitro-3-[oxo-(2-phenyl-4,5-dihydroimidazol-1-yl)methyl]-1-benzopyran-2-one | | coumarins | |
| 2-[[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-(2-pyridinyl)acetamide | | C-nitro compound | |
| N-(3,5-dichlorophenyl)-2-(methanesulfonamido)benzamide | | benzamides | |
| N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(3-pyridinyl)-4-quinolinecarboxamide | | aromatic amide | |
| [4-[(2-chlorophenyl)methyl]-1-piperazinyl]-(6,8-dimethyl-2-pyridin-4-yl-4-quinolinyl)methanone | | quinolines | |
| N-(4-hydroxy-3,5-dimethylphenyl)-2,5-dimethyl-3-thiophenesulfonamide | | sulfonamide | |
| N-(2,4-dimethoxyphenyl)-2-(1-pyrrolidinyl)-4-quinazolinamine | | quinazolines | |
| 4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamide | | aromatic ether | |
| N-[[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]methyl]-1-phenylmethanamine | | pyrazoles;
ring assembly | |
| 4-methoxy-N-[2-[(4-nitrophenyl)methylthio]-4-oxo-3-quinazolinyl]benzamide | | quinazolines | |
| 2-(4-methoxyphenyl)-N-[4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl]acetamide | | acetamides | |
| N-(4-fluorophenyl)-3-([1,2,4]triazolo[4,3-a]quinolin-1-ylthio)propanamide | | quinolines | |
| 3-[[2-[[4-ethyl-5-[(3-methylphenoxy)methyl]-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]benzoic acid | | amidobenzoic acid | |
| 9-(3-bromo-4-hydroxyphenyl)-10-phenyl-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dione | | quinolines | |
| 2-(5-bromo-3-nitro-1,2,4-triazol-1-yl)-N-(diphenylmethyl)acetamide | | diarylmethane | |
| 8,9-dimethyl-N-(3-methylphenyl)-3-[2-(4-morpholinyl)ethyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine | | quinolines | |
| 7-(4-ethyl-1-piperazinyl)-2-(3-fluorophenyl)-5-phenylpyrazolo[1,5-a]pyrimidine | | pyrimidines | |
| 2-[(2-propyl-4-quinazolinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide | | quinazolines | |
| 1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[(2-propyl-4-quinazolinyl)thio]ethanone | | quinazolines | |
| 3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamide | | aromatic amide | |
| N-(5-methyl-3-isoxazolyl)-2-[(2-propan-2-yl-4-quinazolinyl)thio]acetamide | | quinazolines | |
| 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,5-dimethylphenyl)-3-methyl-2-furancarboxamide | | aromatic amide;
furans | |
| 4-tert-butyl-N-[2,5-dimethoxy-4-[[1-oxo-2-(1-piperidinyl)ethyl]amino]phenyl]benzamide | | benzamides | |
| 4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine | | organochlorine compound | |
| 2,5-dichloro-N-(1,5,6-trimethyl-4-benzimidazolyl)benzenesulfonamide | | sulfonamide | |
| 4-[(3-methylphenyl)thio]-2-phenyl-5-pyrimidinecarboxylic acid | | aryl sulfide | |
| 4-(2-quinoxalinylamino)benzoic acid ethyl ester | | quinoxaline derivative | |
| 1-[[[1-(6-methyl-2-pyridinyl)-4-imidazolyl]-oxomethyl]amino]-3-phenylthiourea | | imidazoles | |
| 1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol | | diarylmethane | |
| 5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide | | aromatic amide;
furans | |
| 2-(3,5-dimethyl-4-nitro-1-pyrazolyl)-N-[(2-methyl-4-quinolinyl)methyl]acetamide | | quinolines | |
| 3-[(4-ethylsulfonyl-2-nitrophenyl)thio]-4-methyl-1,2,4-triazole | | aryl sulfide | |
| 6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one | | benzothiazoles | |
| 4-chloro-N-(3,4-dimethoxyphenyl)-1-ethyl-3-pyrazolecarboxamide | | aromatic amide | |
| 5-[(4-methyl-1-piperidinyl)methyl]-1-[4-(1-pyrrolyl)-1,2,5-oxadiazol-3-yl]-4-triazolecarboxylic acid ethyl ester | | aralkylamine | |
| 2-chloro-1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]ethanone | | aromatic ketone | |
| N-[2-[(phenylmethyl)amino]-1,3-benzodioxol-2-yl]carbamic acid ethyl ester | | benzodioxoles | |
| 2-[(4-cyano-1-methyl-5,6,7,8-tetrahydroisoquinolin-3-yl)thio]-N-(3-ethoxyphenyl)acetamide | | anilide | |
| 11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrile | | benzimidazoles | |
| N-(4-methoxyphenyl)-2-(3-methylphenoxy)-N-(4-methylphenyl)sulfonylacetamide | | sulfonamide | |
| cyqualon | cyclovalone: is a synthetic curcumin derivative; structure in first source | | |
| 1-amino-3-[3-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea | | benzenes | |
| 2-chloro-N-heptyl-N-(3-methylphenyl)acetamide | | anilide | |
| 2-chloro-3-(prop-2-enylamino)naphthalene-1,4-dione | | 1,4-naphthoquinones | |
| 3-chloro-N-[3-[[(3-chloro-4-nitrophenyl)-oxomethyl]amino]-2,2-dimethylpropyl]-4-nitrobenzamide | | carbonyl compound;
organohalogen compound | |
| 5-[(4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl)oxymethyl]-2-furancarboxylic acid | | coumarins | |
| N-cyano-N'-(2-fluorophenyl)carbamimidothioic acid [2-(tert-butylamino)-2-oxoethyl] ester | | organofluorine compound | |
| 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione | | triazoles | |
| N-(5-chloro-2-methoxyphenyl)-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine | | methoxybenzenes;
substituted aniline | |
| 5-bromo-3-[[3-(3,3-dimethyl-1-piperidinyl)-1-oxopropyl]amino]-1H-indole-2-carboxylic acid ethyl ester | | indolyl carboxylic acid | |
| N-[[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide | | benzenes | |
| N-bis(2-fluorophenoxy)phosphoryl-3,4-dimethylaniline | | aromatic ether | |
| 2-[6-bromo-4-(2-chlorophenyl)-2-oxo-1H-quinolin-3-yl]acetic acid | | quinolines | |
| 2-[5-(4-chlorophenyl)-1,3,5-dithiazinan-2-ylidene]-2-diethoxyphosphorylacetonitrile | | dialkylarylamine;
tertiary amino compound | |
| LSM-20401 | | aromatic amide | |
| 5-tert-butyl-2-methyl-3-phenyl-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine | | pyrazoles;
ring assembly | |
| 6-(2-chloro-1-oxoethyl)-3H-1,3-benzoxazol-2-one | | benzoxazole | |
| N,N-dimethyl-3-[(2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)thio]-1-propanamine | | aryl sulfide | |
| N-[2-(3,4-dimethoxyphenyl)ethyl]-8-ethoxy-5H-pyrimido[5,4-b]indol-4-amine | | pyrimido-indole | |
| 1-[1-naphthalenyl(oxo)methyl]-3-indolecarboxylic acid methyl ester | | indolecarboxamide | |
| N-[3-(2-methoxyphenyl)-1-methyl-4-oxo-2-quinolinyl]-2-methylpropanamide | | quinolines | |
| 4-(4-chlorophenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | | dihydropyridine | |
| 3,4,5-trimethoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamide | | benzothiazoles | |
| benzotript | benzotript: anti-gastrinic; active group is amide; structure | | |
| 2-(2-bromophenyl)-5-[(7-nitro-4-quinazolinyl)oxymethyl]-1,3,4-oxadiazole | | quinazolines | |
| 1-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)thio]ethanone | | pyrroles | |
| N-(3-cyano-2-thiophenyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]acetamide | | aromatic ether | |
| 2-[(5-chloro-2-thiophenyl)sulfonylamino]-N-(2-furanylmethyl)benzamide | | sulfonamide | |
| 2-chloro-1-[2,5-dimethyl-1-(5-methyl-3-isoxazolyl)-3-pyrrolyl]ethanone | | aromatic ketone | |
| 2-chloro-N-[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]acetamide | | pyrazoles;
ring assembly | |
| N-(2-methyl-1,3-benzothiazol-6-yl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamide | | sulfonamide | |
| 3-(4-methoxyphenyl)-1-phenyl-4-pyrazolamine | | pyrazoles;
ring assembly | |
| 1-[4-(1H-benzimidazol-2-yl)phenyl]-3-[3-(4-morpholinyl)propyl]thiourea | | benzimidazoles | |
| 2-(1H-benzimidazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanone | | benzimidazoles | |
| 1-[4-[(2-hydroxy-5-methylphenyl)-oxomethyl]-1-pyrazolyl]-2-(2-methyl-4-thiazolyl)ethanone | | benzoylpyrazole | |
| 2-chloro-N-(2-phenyl-5-propyl-3-pyrazolyl)acetamide | | pyrazoles;
ring assembly | |
| N-(1H-benzimidazol-2-yl)-3-[methyl-(4-methylphenyl)sulfamoyl]benzamide | | sulfonamide | |
| N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenzamide | | secondary carboxamide | |
| N-(3-acetyl-2-methyl-5-benzofuranyl)-N-(8-quinolinylsulfonyl)acetamide | | quinolines | |
| 4-[2-[[3-(4-methylphenyl)-5-triazolo[1,5-a]quinazolinyl]amino]ethyl]benzenesulfonamide | | quinazolines | |
| N-(4-fluoro-3-methyl-1,3-benzothiazol-2-ylidene)-2-nitrobenzamide | | benzothiazoles | |
| (4-tert-butylphenyl)-[2-(4-fluorophenyl)-8-methyl-3-sulfanylidene-1,4,8-triazaspiro[4.5]dec-1-en-4-yl]methanone | | azaspiro compound | |
| 3-(1H-indol-3-yl)-N-[4-(2-pyrimidinylsulfamoyl)phenyl]propanamide | | tryptamines | |
| 4-[[[5-[(4-chloro-3,5-dimethyl-1-pyrazolyl)methyl]-2-furanyl]-oxomethyl]amino]benzoic acid propan-2-yl ester | | aromatic amide;
furans;
isopropyl ester | |
| mcb-613 | | cyclic ketone;
enone;
pyridines | antineoplastic agent;
steroid receptor coactivator stimulator |
| 6-bromo-3-[4-nitro-3-(trifluoromethyl)phenyl]-2-propyl-4-quinazolinone | | quinazolines | |
| 4-[(2,4-dichlorophenoxy)methyl]-N-[2-(dimethylamino)ethyl]benzamide | | benzamides | |
| N-[4-(1H-benzimidazol-2-yl)phenyl]-2,3,4,5,6-pentafluorobenzamide | | benzimidazoles | |
| 2,5-dimethoxybenzenesulfonic acid (1,3-dioxo-2-isoindolyl) ester | | phthalimides | |
| 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetic acid (4-chlorophenyl) ester | | benzoate ester;
phenols | |
| 1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-[(4-chlorophenyl)methyl]thiourea | | furoic acid | |
| 1-[[(4-bromo-2-methyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxy-5-methylphenyl)thiourea | | methoxybenzenes;
substituted aniline | |
| 5-[(2-chlorophenyl)methylsulfonyl]-1-(2,6-dimethylphenyl)tetrazole | | tetrazoles | |
| N-[(3-ethoxy-2-prop-2-enoxyphenyl)methyl]-2-thiazolamine | | aromatic ether | |
| 6-bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(2-pyridinyl)-4-quinolinecarboxamide | | quinolines | |
| N-(2-naphthalenyl)-2-[[6-[[[2-(2-naphthalenylamino)-2-oxoethyl]thio]methyl]-2-pyridinyl]methylthio]acetamide | | naphthalenes | |
| N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-dibenzofuransulfonamide | | dibenzofurans | |
| N-(2-fluorophenyl)-4-methoxy-2,5-dimethylbenzenesulfonamide | | sulfonamide | |
| 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(5,7-diphenyl-2-pyrazolo[1,5-a]pyrimidinyl)methanone | | pyrimidines | |
| 2-[benzenesulfonyl-(phenylmethyl)amino]-N-ethylacetamide | | sulfonamide | |
| 2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acid | | benzamides | |
| N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-propan-2-ylphenyl) ester | | alkylbenzene | |
| 3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamide | | benzamides | |
| 1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thiourea | | organochlorine compound;
quinolines | |
| 1-[2-[3-(1-methylethenyl)phenyl]propan-2-yl]-3-(4-methyl-2-pyridinyl)urea | | olefinic compound | |
| 2-(1,3-benzothiazol-2-yl)-5-methyl-3-pyrazolamine | | benzothiazoles | |
| N-(1H-benzimidazol-2-yl)-4-(dimethylsulfamoyl)benzamide | | sulfonamide | |
| N-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethenyl]-4-morpholinecarboxamide | | morpholines | |
| 3-[2-(4-fluorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine | | quinolines | |
| N-[[2-(diethylamino)ethylamino]-sulfanylidenemethyl]-3-(4-methoxyphenyl)-1-phenyl-4-pyrazolecarboxamide | | pyrazoles;
ring assembly | |
| 1,2,3,4-tetrahydroacridine-9-carboxylic acid [2-(3-chloro-4-methoxyanilino)-2-oxoethyl] ester | | acridines | |
| 3-methyl-5-[[1-oxo-2-(2-pyridinylmethylamino)ethyl]amino]thiophene-2,4-dicarboxylic acid diethyl ester | | amino acid amide | |
| N-[[2-(1-cyclohexenyl)ethylamino]-sulfanylidenemethyl]-2-furancarboxamide | | furoic acid | |
| 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] ester | | aromatic ether | |
| N,N-diethyl-2-[(4-fluorophenyl)methylthio]-1,3-benzoxazole-5-sulfonamide | | benzoxazole | |
| 2-[(1-oxido-2-pyridin-1-iumyl)thio]-1-(4-phenylphenyl)ethanone | | aromatic ketone | |
| 4-(4-methoxyanilino)-2,5-dimethyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl ester | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound;
thienopyrimidine | |
| N-[(1-adamantylamino)-oxomethyl]-2-chloroacetamide | | N-acylurea | |
| 4-methoxy-3-[2-phenylethyl-(phenylmethyl)sulfamoyl]benzoic acid | | methoxybenzoic acid | |
| 2-chloro-N-[4-(N-propan-2-ylanilino)phenyl]acetamide | | aromatic amine;
tertiary amino compound | |
| 2-[5-(1-pyrrolidinylsulfonyl)-2-thiophenyl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide | | sulfonamide | |
| 2-hydroxy-4-methylbenzoic acid [2-(2-chloroanilino)-2-oxoethyl] ester | | benzoate ester;
phenols | |
| 2-chloro-N-[3-[(2-chlorophenyl)methyl]-2-thiazolylidene]acetamide | | organochlorine compound | |
| 2-(1-benzimidazolyl)acetic acid [2-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester | | alpha-amino acid ester | |
| 2,5-dimethyl-1-(3-methylphenyl)-N-(4-methylphenyl)-3-pyrrolecarboxamide | | aromatic amide | |
| 5-bromo-2-furancarboxylic acid [2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester | | carboxylic ester | |
| 2-[(3-acetyl-5-oxo-4H-imidazol-2-yl)thio]-N-(4-methyl-5-phenyl-2-thiazolyl)-N-prop-2-enylacetamide | | organonitrogen compound;
organooxygen compound | |
| 4-[(1-methyl-5-tetrazolyl)thio]-5-phenylthieno[2,3-d]pyrimidine | | aryl sulfide;
thienopyrimidine | |
| 2-chloro-1-[1-[2-(4-chlorophenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone | | aromatic ketone | |
| 2-chloro-N-[4-[(3,4-dimethylphenyl)thio]phenyl]acetamide | | aryl sulfide | |
| N-(1,3-benzodioxol-5-yl)-2-chloro-N-[(2-prop-2-enoxyphenyl)methyl]acetamide | | benzodioxoles | |
| 2-chloro-1-[4-[(3-methylphenyl)methyl]-1-piperazinyl]ethanone | | aromatic amine | |
| 2-(2,3-dichlorophenoxy)-N-(2,3-dihydro-1H-inden-5-yl)acetamide | | indanes | |
| 4-methyl-N-[1-methyl-2-oxo-6-(trifluoromethyl)-3-pyridinyl]benzamide | | benzamides | |
| 3,4-dimethoxy-N-(2-methyl-1,3-benzothiazol-6-yl)benzamide | | dimethoxybenzene | |
| 2-chloro-N-[(5-chloro-2-thiophenyl)methyl]-N-methylacetamide | | thiophenes | |
| 2-(2,4-dichlorophenoxy)-N-[2-(methylthio)phenyl]acetamide | | anilide | |
| N'-(4-quinazolinyl)acetohydrazide | | quinazolines | |
| N-[2-(1-cyclohexenyl)ethyl]-1-phenyl-5-tetrazolamine | | tetrazoles | |
| 1-[4-(3-chloro-2,4,6-trifluorophenyl)sulfonyl-1-piperazinyl]ethanone | | sulfonamide | |
| 3-(diethylsulfamoyl)benzoic acid [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl] ester | | benzoate ester | |
| 2-chloro-N-(2-chloro-5-methylsulfonylphenyl)acetamide | | anilide | |
| 5,6-dimethyl-N-[2-methyl-2-(4-morpholinyl)propyl]-4-thieno[2,3-d]pyrimidinamine | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound;
thienopyrimidine | |
| 4,5-dichloro-2-[2-[2,5-dimethyl-1-(2,2,2-trifluoroethyl)-3-pyrrolyl]-2-oxoethyl]-3-pyridazinone | | aromatic ketone | |
| N-[3-(4-morpholinyl)propyl]-3-(3-pyridinyl)-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine | | organonitrogen heterocyclic compound | |
| 2-[(3-butyl-4-oxo-2-quinazolinyl)thio]-N-cyclopropylacetamide | | quinazolines | |
| N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamide | | benzamides | |
| 2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile | | nitrile;
pyridines | |
| 5-(2-chloroanilino)-3-oxo-4-isothiazolecarbonitrile | | substituted aniline | |
| N-benzyl-N'-methyl-N-(pyridin-3-ylmethyl)thiourea | | pyridines | |
| 5-Methyl-6-(2-thienyl)-2,3,4,5-tetrahydropyridazin-3-one | | pyridazines | |
| 3-(4-Chloroanilino)propanoic acid | | organonitrogen compound;
organooxygen compound | |
| 2-phenyl-N-(2-piperidin-1-ylethyl)quinolin-4-amine | | quinolines | |
| 6-cyclohex-3-enyl-5-nitropiperidin-2-one | | piperidones | |
| 3-(tert-butyl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one | | pyrazoles | |
| 2,2-dimethyl-N-pyridin-4-yl-3H-benzofuran-7-carboxamide | | 1-benzofurans | |
| N,N-diethyl-5-thiophen-2-yl-2-thiophenecarboxamide | | ring assembly;
thiophenes | |
| 3-(tert-butylsulfamoyl)-4-phenyl-5-(trifluoromethyl)-2-thiophenecarboxylic acid methyl ester | | thiophenecarboxylic acid | |
| 4-(2-fluorophenyl)-N-(2-methylbut-3-yn-2-yl)benzamide | | biphenyls | |
| N'-[(4-chlorophenyl)-oxomethyl]-2-methyl-4-thiazolecarbohydrazide | | carbonyl compound;
organohalogen compound | |
| N-(4-chlorophenyl)-2-[[4-methyl-5-[4-methyl-2-(5-methyl-3-isoxazolyl)-5-thiazolyl]-1,2,4-triazol-3-yl]thio]acetamide | | anilide | |
| N-(2-chlorophenyl)-2-[[5-[5-(trifluoromethyl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | | anilide | |
| N-(6-methoxy-3-pyridinyl)-2-thiophenecarboxamide | | aromatic amide;
thiophenes | |
| 3-[[(2,4-dichlorophenyl)methylthio]methyl]-4-propan-2-yl-1H-1,2,4-triazole-5-thione | | dichlorobenzene | |
| 2,6-dichlorobenzoic acid [3-cyano-6-(3-methoxyphenyl)-2-pyridinyl] ester | | phenylpyridine | |
| 3-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole | | pyrazoles;
ring assembly | |
| 2-(2-Thienyl)-1,3-thiazole-4-carboxylic acid | | aromatic carboxylic acid;
thiazoles | |
| 6-methoxy-3-nitro-2-(phenylsulfonyl)pyridine | 6-methoxy-3-nitro-2-(phenylsulfonyl)pyridine: inhibitor of SARS-CoV main protease; structure in first source | sulfonic acid derivative | anticoronaviral agent |
| 3-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid ethyl ester | | aryl sulfide | |
| N-[amino(1-pyrrolidinyl)methylidene]-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamide | | dichlorobenzene | |
| 2,6-dimethoxy-N-(1-methyl-1H-pyrazol-5-yl)benzamide | | dimethoxybenzene | |
| 5-tert-butyl-N-(4-fluorophenyl)-2-[(4-fluorophenyl)methyl]-3-pyrazolecarboxamide | | aromatic amide | |
| 5-[[[5-(4-chlorophenyl)-2-(trifluoromethyl)-3-furanyl]-oxomethyl]amino]-2-(4-morpholinyl)benzoic acid methyl ester | | aromatic amide;
furans | |
| 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[2-(4-fluorophenyl)sulfonylethylthio]-1H-1,2,4-triazol-5-one | | triazoles | |
| N'-(3-chloro-4-methylphenyl)-5-isoxazolecarbohydrazide | | phenylhydrazines | |
| 2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-isoindole-1,3(2H)-dione | | phthalimides | |
| 2-[4-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrimidine | | imidazoles | |
| N-{5-[(dimethylamino)sulfonyl]-2-methylphenyl}cyclohexanecarboxamide | | sulfonamide | |
| LSM-28486 | | pyrazolopyrimidine | |
| 3,3-dimethyl-5-oxo-5-[(3-phenyl-1H-pyrazol-5-yl)amino]pentanoic acid | | pyrazoles;
ring assembly | |
| 2-amino-4-(2-chlorophenyl)-6-[(4-chlorophenyl)thio]pyridine-3,5-dicarbonitrile | | phenylpyridine | |
| 2-[5-[(3-chlorophenyl)thio]-2-thiophenyl]pyridine | | aryl sulfide | |
| 8-methylsulfinyl-4,5-dihydrothieno[3,4-g][2,1]benzoxazole-6-carboxylic acid ethyl ester | | thiophenecarboxylic acid | |
| 2-[4-(2-methylpropyl)phenyl]propanoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | | monoterpenoid | |
| 3,3,3-trifluoro-2-hydroxy-2-[4-[methoxycarbonyl(methyl)amino]phenyl]propanoic acid methyl ester | | carbamate ester | |
| 3-[[sulfanylidene-[[2,2,2-trichloro-1-[[(3-nitrophenyl)-oxomethyl]amino]ethyl]amino]methyl]amino]benzoic acid | | thioureas | |
| 4,6-dimorpholino-n-(4-nitrophenyl)-1,3,5-triazin-2-amine | 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine: an mTOR activator; structure in first source | | |
| (4-chlorophenyl)-[6,7-dichloro-4-[(dimethylamino)methyl]-5-hydroxy-2-methyl-3-benzofuranyl]methanone | | aromatic ketone | |
| N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamine | | N-alkylpyrrolidine | |
| N-[2-(4-chlorophenoxy)ethyl]-5-(3,5-dimethyl-1-piperazinyl)-2-nitroaniline | | piperazines | |
| 2-(4,6,7-Trimethyl-2-quinazolinyl)guanidine | | quinazolines | |
| 4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxaline | | pyrroline | |
| 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid (4-methoxyphenyl)methyl ester | | methoxybenzenes;
phenols | |
| 2-[[2-methyl-5-nitro-3-(phenylmethyl)-4-imidazolyl]thio]-6-nitro-1H-benzimidazole | | aryl sulfide | |
| N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide | | hydroxyquinoline | |
| N-(3-bicyclo[2.2.1]heptanyl)-4-chlorobenzenesulfonamide | | monoterpenoid | |
| N-[4-methyl-5-[2-(3-nitroanilino)-4-thiazolyl]-2-thiazolyl]acetamide | | C-nitro compound | |
| N-(4-fluorophenyl)-4-(4-nitrophenyl)-1-piperazinecarbothioamide | | piperazines | |
| 4-chloro-3-(diethylsulfamoyl)-N-(2-nitrophenyl)benzamide | | benzamides | |
| 2-[(4-chlorophenyl)thio]-N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]propanamide | | sulfonamide | |
| 1-butyl-3-(2-hydroxyethylamino)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile | | aminopyridine | |
| 4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-methoxyphenyl] ester | | benzenesulfonate ester | |
| (3-amino-5-nitro-2-benzofuranyl)-phenylmethanone | | aromatic ketone | |
| 3-acetamidobenzoic acid [2-(4-methylphenyl)-2-oxo-1-phenylethyl] ester | | benzoins | |
| 1-(3,4-dimethylphenyl)-3-(2-pyrimidinylthio)pyrrolidine-2,5-dione | | pyrrolidines | |
| N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-9H-xanthene-9-carboxamide | | xanthenes | |
| 4-ethoxy-N-(3-quinolinyl)benzenesulfonamide | | quinolines | |
| 2-(3-hydroxyphenyl)-6-(1-piperidinyl)benzo[de]isoquinoline-1,3-dione | | isoquinolines | |
| N-[4-(butylsulfamoyl)phenyl]-2-phenyl-2-(phenylthio)acetamide | | sulfonamide | |
| 1-[4-(3,4-dihydroxyphenyl)-6-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]ethanone | | olefinic compound | |
| importazole | importazole: an importin-8 inhibitor; structure in first source | quinazolines | |
| 4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamide | | sulfonamide | |
| N-[amino-[2-(1H-indol-3-yl)ethylimino]methyl]-4-chlorobenzamide | | indoles | |
| 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)thio]-N-(2-methoxy-3-dibenzofuranyl)acetamide | | dibenzofurans | |
| 5-chloro-7-[3-pyridinyl-(2-pyridinylamino)methyl]-8-quinolinol | | organochlorine compound;
quinolines | |
| 1-[2-(hydroxymethyl)-1-benzimidazolyl]-3-(1-indolyl)-2-propanol | | indoles | |
| 1-[3-[4-(2-chloro-5-methoxyphenyl)-1-piperazinyl]propyl]-3-(4-methylphenyl)urea | | piperazines | |
| 2-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-hydroxy-3-phenyl-1-isoindolone | | pyrazoles;
ring assembly | |
| 1-(4-methoxy-2-nitrophenyl)-4-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)piperazine | | piperazines | |
| cb 7969312 | | organochlorine compound;
quinolines | |
| 4H-[1,3]thiazino[3,2-a]benzimidazol-4-ol | | benzimidazoles | |
| 2-[1-(4-chlorophenyl)-5-oxo-3-(2-pyridin-4-ylethyl)-2-sulfanylidene-4-imidazolidinyl]-N-(4-fluorophenyl)acetamide | | imidazolidines | |
| N-[4-[(3-acetylphenyl)sulfamoyl]phenyl]-1-piperidinecarboxamide | | aromatic ketone | |
| 1-(1,3-benzodioxol-5-yl)-3-[4-(4-hydroxyphenyl)-1-piperazinyl]pyrrolidine-2,5-dione | | piperazines | |
| 1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[[1-(2-methylpropyl)-2-benzimidazolyl]thio]ethanone | | sulfonamide | |
| 1-[2-hydroxy-3-[4-(2-methylbutan-2-yl)phenoxy]propyl]-4-piperidinecarboxylic acid ethyl ester | | carboxylic acid;
piperidines | |
| 3-[[5,5-dimethyl-3-(4-morpholinyl)-1-cyclohex-2-enylidene]amino]-N,N-dimethylaniline | | dialkylarylamine;
tertiary amino compound | |
| N-[1-oxo-1-[[4-(2-pyridinyl)-2-thiazolyl]amino]propan-2-yl]-2-furancarboxamide | | N-acyl-amino acid | |
| N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-3-pyrrolidinecarboxamide | | amphetamines | |
| dasatinib | dasatinib (anhydrous) : An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN).
N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide: a dasatinib prodrug; structure in first source | 1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor |
| 3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide | | aromatic ether;
C-nitro compound | |
| 2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amine | | benzimidazoles | |
| N-methyl-5-nitro-N-(phenylmethyl)-2-furancarboxamide | | C-nitro compound;
furans | |
| 2-[[2,2,2-trichloro-1-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester | | thiophenecarboxylic acid | |
| N-[3-(1,3-benzothiazol-2-ylthio)-5-nitrophenyl]-2-fluorobenzamide | | benzamides | |
| phenyl-(2-thiophen-2-yl-5,10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)methanone | | aromatic ketone | |
| 2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile | | indoles | |
| N'-[(2-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazide | | aromatic carboxylic acid;
pyridinemonocarboxylic acid | |
| N-[[5-[(4-chlorophenyl)methylthio]-4-phenyl-1,2,4-triazol-3-yl]methyl]-4-ethoxyaniline | | triazoles | |
| 3-nitro-N-(pyridin-4-ylmethyl)benzenesulfonamide | | sulfonamide | |
| 1-[3-(benzenesulfonyl)-2-(1-piperidinyl)propyl]piperidine | | sulfonamide | |
| 6-amino-5,7,7-tricyano-8-pyridin-4-yl-1,3,8,8a-tetrahydroisoquinoline-2-carboxylic acid (phenylmethyl) ester | | carboxylic ester | |
| 5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione | | indoles | |
| N-(2-methoxyphenyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | | aromatic amide | |
| 2-chloro-N-(3-ethyl-2-oxo-1,3-benzoxazol-6-yl)acetamide | | benzoxazole | |
| N-[2-[1-methyl-5-[[(4-methylphenyl)-oxomethyl]amino]-2-benzimidazolyl]ethyl]-2-furancarboxamide | | benzimidazoles | |
| 1,6-dimethyl-3-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione | | pyrimidotriazine | |
| 4-amino-N5-(4-butoxyphenyl)-N5-[2-(cyclohexylamino)-2-oxoethyl]isothiazole-3,5-dicarboxamide | | aromatic amide | |
| N-[2-(tert-butylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2-oxolanylmethyl)-5-phenyl-1H-pyrrole-2-carboxamide | | pyrroles | |
| 1-[2-(diethylamino)ethyl]-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-3-(2-oxolanylmethyl)thiourea | | quinolines | |
| N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-5-methyl-N-(thiophen-2-ylmethyl)-2,1,3-benzothiadiazole-4-sulfonamide | | quinolines | |
| 4-(2-azaspiro[5.5]undecan-2-ylsulfonyl)-N-butan-2-ylbenzenesulfonamide | | azaspiro compound | |
| 2-[(3,6-dimethyl-2-quinolinyl)thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone | | quinolines | |
| 3-(2,4-dimethoxyphenyl)-1-[(1-ethyl-2-pyrrolidinyl)methyl]-1-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]thiourea | | quinolines | |
| CID 3192987 | | N-arylpiperazine | anticoronaviral agent |
| [4-(2,7-dimethyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-(2-furanyl)methanone | | N-arylpiperazine | |
| 2-[2-[[2-[[1-(2,4-dimethylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester | | tetrazoles | |
| N-(4-Butan-2-ylphenyl)-N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]furan-2-carboxamide | | aromatic amide;
furans | anticoronaviral agent |
| 2-[2-methoxyethyl-(1-oxo-2-thiophen-2-ylethyl)amino]-N-[(4-methoxyphenyl)methyl]-2-(4-propan-2-ylphenyl)acetamide | | monoterpenoid | |
| 2-[[5-(4-fluorophenyl)-1-methyl-2-imidazolyl]thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone | | imidazoles | |
| 1-[9-[(4-fluorophenyl)methyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-(2-phenylphenyl)urea | | piperidines | |
| 1-(9-cyclopentyl-9-azabicyclo[3.3.1]nonan-3-yl)-3-(3,5-dimethylphenyl)thiourea | | thioureas | |
| N1-cyclohexyl-N2-cyclopropylpyrrolidine-1,2-dicarboxamide | | proline derivative | |
| 1-[2-[(3-cyano-5,7-dimethyl-2-quinolinyl)amino]ethyl]-3-(3-methoxypropyl)thiourea | | aminoquinoline | |
| [4-[5-tert-butyl-3-(phenylmethyl)-7-triazolo[4,5-d]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanone | | N-arylpiperazine | |
| N-[2-(3-fluorophenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-N',N'-dimethylpropane-1,3-diamine | | pyrimidines | |
| 1-[(4-fluorophenyl)methyl]-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-oxo-3H-benzimidazole-5-carboxamide | | aromatic amide | |
| 2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl ester | | benzothiazoles | |
| 2-[(3-methoxyphenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester | | benzoic acids | |
| N-[3-(diethylamino)propyl]-6-(4-fluorophenyl)-3-methyl-2-imidazo[2,1-b]thiazolecarboxamide | | imidazoles | |
| 4-[[2-(4-methoxyphenyl)-6-imidazo[2,1-b][1,3]benzothiazolyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester | | imidazoles | |
| 4-[(1-methyl-2-oxo-4-quinolinyl)oxy]-N-(4-methyl-2-pyridinyl)butanamide | | quinolines | |
| 5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinol | | hydroxyquinoline | |
| N-(2,3-dihydro-1H-inden-5-yl)-2-[(4-hydroxy-6-oxo-1H-pyrimidin-2-yl)thio]acetamide | | indanes | |
| 5-bromo-N-[2-(2-chlorophenyl)-1,3-benzoxazol-5-yl]-3-pyridinecarboxamide | | 1,3-oxazoles | |
| 3-chloro-4-ethoxy-N-[3-(2-oxazolo[5,4-b]pyridinyl)phenyl]benzamide | | benzamides | |
| 3,7-dimethyl-2-(methylthio)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 5-methyl-N-(5-methyl-2-phenyl-3-pyrazolyl)-3-isoxazolecarboxamide | | pyrazoles;
ring assembly | |
| 1-[[2-(4-chlorophenyl)-5-methyl-4-oxazolyl]methyl]-N-[2-(dipropylamino)ethyl]-4-piperidinecarboxamide | | 1,3-oxazoles | |
| N-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]-1,3-benzodioxole-5-carboxamide | | piperazines;
pyridines | |
| 2-[[2-(3,4-dimethoxyphenyl)-5-methyl-4-oxazolyl]methylsulfinyl]-N-[3-(1-pyrrolidinyl)propyl]acetamide | | 1,3-oxazoles | |
| 6-[(2-ethylphenyl)sulfamoyl]-N-(2-furanylmethyl)-4-oxo-1H-quinoline-3-carboxamide | | aromatic amide;
quinolines | |
| 2-amino-4-[5-methyl-2-(methylthio)-3-thiophenyl]-5-oxo-1-(3-pyridinyl)-4,6,7,8-tetrahydroquinoline-3-carbonitrile | | aryl sulfide | |
| N-(3,4-dimethylphenyl)-3-[(4-fluorophenyl)methyl]-1,3-diazinane-1-carboxamide | | ureas | |
| 2-[[3-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-2-thieno[3,2-d]pyrimidinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamide | | dimethoxybenzene | |
| 4-[dimethylamino(oxo)methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester | | ethyl ester;
pyrroles;
tertiary carboxamide | |
| 2-[3-[3-(2-furanylmethylamino)-3-oxopropyl]-2,4-dioxo-1-thieno[3,2-d]pyrimidinyl]acetic acid (phenylmethyl) ester | | alpha-amino acid ester | |
| N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-4-piperidinecarboxamide | | 1,3-oxazoles | |
| N-butan-2-yl-6-[(4-ethoxyphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamide | | aromatic amide;
quinolines | |
| 3-methyl-5-(4-morpholinylsulfonyl)-N-(2-pyridinylmethyl)-2-benzofurancarboxamide | | benzofurans | |
| 4-[3-(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)-1-oxopropyl]-1-piperazinecarboxylic acid ethyl ester | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamide | | benzenes;
sulfonamide | |
| 2-(6-amino-5-cyano-3-thiophen-2-yl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)benzoic acid | | benzoic acids;
pyranopyrazole | |
| 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide | | sulfonamide | |
| N-[4-(difluoromethoxy)phenyl]-4-(phenylmethyl)-1-piperazinecarbothioamide | | thioureas | |
| N4-(1,1-dioxo-3-thiolanyl)-5-nitropyrimidine-4,6-diamine | | C-nitro compound | |
| 2-amino-7,7-dimethyl-5-oxo-4-[1-phenyl-3-(4-propan-2-ylphenyl)-4-pyrazolyl]-6,8-dihydro-4H-1-benzopyran-3-carbonitrile | | pyrazoles;
ring assembly | |
| N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide | | oxadiazole;
ring assembly | |
| 2-(2-methoxyphenyl)-1-methyl-3,5-dinitro-2H-pyridine | | methoxybenzenes | |
| N-[(4-methoxyphenyl)methyl]-2-(phenylmethyl)-4-thiazolecarboxamide | | aromatic amide;
thiazoles | |
| 5-(diethylsulfamoyl)-2-hydroxybenzoic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester | | benzoate ester;
phenols | |
| 1-(3-methoxyphenyl)-3-[5-(2-methyl-1-piperidinyl)-1,3,4-thiadiazol-2-yl]urea | | ureas | |
| 1-(3,4-dichlorophenyl)-3-[1-(4-morpholinyl)-1-phenylpropan-2-yl]urea | | ureas | |
| N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester | | organonitrogen compound;
organosulfur compound | |
| 5-chloro-7-[1-piperidinyl(2-pyridinyl)methyl]-8-quinolinol | | organochlorine compound;
quinolines | |
| LSM-16990 | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 6-amino-5-cyano-4-(2-fluorophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyridine-3-carboxamide | | organonitrogen compound;
organooxygen compound | |
| 2-benzoylimino-1-(2-furanylmethyl)-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxylic acid ethyl ester | | pyridopyrimidine | |
| N-[5-ethyl-3-[(4-fluorophenyl)-(4-morpholinyl)methyl]-2-thiophenyl]benzamide | | benzamides | |
| 1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol | | indoles | anticoronaviral agent |
| 1-(4-butylphenyl)-3-[4-chloro-3-(dimethylsulfamoyl)phenyl]thiourea | | sulfonamide | |
| 2-[[2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]thio]acetic acid butyl ester | | organofluorine compound | |
| N-[[4-[[4-(4-fluorophenyl)-1-piperazinyl]-oxomethyl]cyclohexyl]methyl]-2-thiophenesulfonamide | | piperazines | |
| N'-[(3-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazide | | aromatic carboxylic acid;
pyridinemonocarboxylic acid | |
| 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(4-morpholinylsulfonyl)phenyl]-4-quinolinecarboxamide | | quinolines | |
| 2-chloro-N-(3-methyl-1,3-benzothiazol-2-ylidene)acetamide | | benzothiazoles | |
| 3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thione | | aromatic ether | |
| ML162 | ML162 : A monochlorobenzene that is benzene substituted by (chloroacetyl){2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}amino, chloro and methoxy groups at positions 1, 3 and 4, respectively. It is a covalent inhibitor of glutathione peroxidase 4 (GPX4) that induces ferroptosis in cells. | monochlorobenzenes;
monomethoxybenzene;
organochlorine compound;
secondary carboxamide;
tertiary carboxamide;
thiophenes | EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer |
| 2-(N-(2-chloro-1-oxoethyl)-3-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide | | organonitrogen compound;
organooxygen compound | |
| 2-(N-(2-chloro-1-oxoethyl)-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide | | organonitrogen compound;
organooxygen compound | |
| 2-(cyclohexylamino)-N-[(diphenylmethylene)amino]propanamide | | diarylmethane | |
| 5-[3-[[(4-methylphenyl)-oxomethyl]hydrazo]-2,5-dioxo-1-pyrrolidinyl]benzene-1,3-dicarboxylic acid dimethyl ester | | amidobenzoic acid | |
| 4-chloro-N-(2-methoxy-1-phenazinyl)benzamide | | phenazines | |
| 3-ethyl-2-sulfanylidene-5-thiophen-2-yl-1H-thieno[2,3-d]pyrimidin-4-one | | ring assembly;
thiophenes | |
| LSM-1924 | | organic heterotricyclic compound;
organooxygen compound | |
| 2-[1-(2-methylphenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile | | aromatic ketone | |
| N4-(3-fluorophenyl)-N2-[3-(4-morpholinyl)propyl]-5-nitropyrimidine-2,4,6-triamine | | C-nitro compound | |
| 2-(4-chlorophenyl)-5-methyl-4-oxo-2,3-dihydro-1H-thieno[3,4-d]pyrimidine-7-carboxylic acid ethyl ester | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamide | | aromatic ether | |
| 4-(2-methylcyclohexyl)-3-(3-pyridinyl)-1H-1,2,4-triazole-5-thione | | triazoles | |
| 1-bromo-3-(5,5-dimethyl-3-phenyl-4H-pyrazolo[4,3-a]carbazol-10-yl)-2-propanol | | carbazoles | |
| 5-tert-butyl-7-(4-ethyl-1-piperazinyl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine | | N-arylpiperazine | |
| 2-Chloro-1-[5-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one | | dimethoxybenzene | anticoronaviral agent |
| N-(4-phenylmethoxyphenyl)-3-[4-(phenylmethyl)-1-piperazinyl]propanamide | | organonitrogen compound;
organooxygen compound | |
| 1-(4-chlorophenyl)-3-[2-(2-furanylmethyl)cyclohexyl]urea | | ureas | |
| 4-[(2-hydroxy-3-nitrophenyl)-(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-1H-pyrazol-3-one | | pyrazoles;
ring assembly | |
| 1-[4-(3-chlorophenyl)-1-piperazinyl]-2-phenyl-1-butanone | | piperazines | |
| 2-furanyl-[4-(4-propan-2-ylphenyl)sulfonyl-1-piperazinyl]methanone | | sulfonamide | |
| 1-(Chloroacetyl)-5-[4-(difluoromethoxy)-3-methoxyphenyl]-3-thien-2-yl-4,5-dihydro-1H-pyrazole | | methoxybenzenes | anticoronaviral agent |
| 6-nitro-3-phenyl-1H-benzimidazole-2-thione | | benzimidazoles | |
| LSM-22738 | | organic heterotricyclic compound;
organooxygen compound | |
| fg 9041 | FG 9041: structure given in first source | quinoxaline derivative | |
| N-(3,5-dichloro-2-pyridinyl)-2-[(4-methyl-2-quinolinyl)thio]propanamide | | quinolines | |
| 4-chloro-5-(2,3-dihydro-1,4-benzodioxin-3-yl)thieno[2,3-d]pyrimidine | | benzodioxine;
thienopyrimidine | |
| 2-(1H-benzimidazol-2-yl)-5-methyl-4-(phenylmethyl)-4H-pyrazol-3-one | | benzimidazoles | |
| N-(1,1-dioxo-3-thiolanyl)-N-ethyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)acetamide | | triazolopyridine | |
| 4-tert-butylbenzoic acid [2-[(2-methoxy-3-dibenzofuranyl)amino]-2-oxoethyl] ester | | dibenzofurans | |
| N-[3-(dimethylsulfamoyl)-4-methylphenyl]-2-quinolinecarboxamide | | aromatic amide | |
| 4-oxo-4-thiophen-2-ylbutanoic acid [2-(ethylamino)-2-oxoethyl] ester | | oxo carboxylic acid | |
| N-[2-(2-methyl-1H-indol-3-yl)ethyl]-1-nitro-9,10-dioxo-2-anthracenecarboxamide | | anthraquinone | |
| 1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thiourea | | indoles | |
| [4-[(2-chlorophenyl)methylsulfonyl]-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | | piperazines;
pyridines | |
| 2-amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-1-(3-pyridinyl)-6,8-dihydro-4H-quinoline-3-carbonitrile | | quinolines | |
| 7-chloro-4-[(2-fluorophenyl)-oxomethyl]-5-phenyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one | | benzodiazepine | |
| 4-amino-3-(3,4-dimethylphenyl)-N-(2-fluorophenyl)-2-sulfanylidene-5-thiazolecarboxamide | | aromatic amide | |
| 2-(5-bromo-2-thiophenyl)-N-(4-methyl-1-piperazinyl)-4-quinolinecarboxamide | | quinolines | |
| [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(4-propan-2-ylphenyl)-4-quinolinyl]methanone | | quinolines | |
| 2-methoxy-N-(5-phenyl-1,2,4-thiadiazol-3-yl)benzamide | | benzamides | |
| 7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine | | pyrazoles;
ring assembly | |
| LSM-16386 | | monoterpenoid | |
| 2-(4-methoxyphenyl)sulfonylquinoxaline | | quinoxaline derivative | |
| N-[1-(1H-benzimidazol-2-yl)ethyl]-3-(dimethylsulfamoyl)benzamide | | sulfonamide | |
| 2-(hexylamino)-1-[4-(phenylmethyl)-1-piperidinyl]ethanone | | piperidines | |
| 5-(4-fluorophenyl)-7-(3-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine | | triazolopyrimidines | |
| N-[3-(N-(2-chloro-1-oxoethyl)-4-nitroanilino)propyl]-2,2,2-trifluoroacetamide | | C-nitro compound;
secondary carboxamide;
tertiary carboxamide;
trifluoroacetamide | |
| 1-[(2,4-dichlorophenyl)methyl]-4-(methylthio)-2-oxo-6-phenyl-3-pyridinecarbonitrile | | phenylpyridine | |
| 6-benzoyl-2-phenyl-5-(trifluoromethyl)-3-pyridazinone | | aromatic ketone | |
| N-[3-(4-morpholinylsulfonyl)phenyl]-4-(2-oxo-1-pyrrolidinyl)benzamide | | benzamides | |
| 4-(3-chlorophenyl)sulfonyl-N-cyclohexyl-N-methyl-3-nitrobenzamide | | C-nitro compound | |
| 6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine | | C-nitro compound | |
| N-[1-(benzenesulfonyl)-2,2-dichloroethenyl]-4-methylbenzamide | | benzamides | |
| N-(3-methoxyphenyl)-1,3-dioxo-2-(2-oxolanylmethyl)-5-isoindolecarboxamide | | aromatic amide | |
| iododiflunisal | iododiflunisal: an amyloid inhibitor; structure in first source | | |
| 2-(N-(2-chloro-1-oxoethyl)-4-fluoroanilino)-N-cyclohexyl-2-(3-pyridinyl)acetamide | | organonitrogen compound;
organooxygen compound | |
| 2-(N-(2-chloro-1-oxoethyl)-4-methoxyanilino)-N-cyclohexyl-2-(3-pyridinyl)acetamide | | organonitrogen compound;
organooxygen compound | |
| 2-(3-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(3-pyridinyl)acetamide | | organonitrogen compound;
organooxygen compound | |
| 4-(2,5-dioxo-1-pyrrolidinyl)-N-[4-(4-methoxyphenyl)-2-thiazolyl]benzamide | | amidobenzoic acid | |
| 1-(3-chlorophenyl)-3-[2-(dimethylamino)-2-phenylethyl]thiourea | | thioureas | |
| 5-nitro-2-furancarboxylic acid [2-oxo-2-[3-(1-piperidinylsulfonyl)anilino]ethyl] ester | | sulfonamide | |
| 3-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethyl]-1,1-bis(phenylmethyl)urea | | organofluorine compound | |
| N-[4-chloro-3-[(4-chlorophenyl)sulfamoyl]phenyl]-4-propan-2-yloxybenzamide | | benzamides | |
| 4-bromo-N-[(2,8-dimethyl-3,4,4a,9b-tetrahydro-1H-pyrido[4,3-b]indol-5-yl)-sulfanylidenemethyl]benzamide | | carbonyl compound;
organohalogen compound | |
| N-(3-chlorophenyl)-2-[4-oxo-2-phenylimino-3-(2-pyridinylmethyl)-5-thiazolidinyl]acetamide | | anilide | |
| 2-chloro-N-(1,2-diphenylethyl)acetamide | | stilbenoid | |
| 1-(2-methoxy-3-dibenzofuranyl)-3-(3-methylphenyl)thiourea | | dibenzofurans | |
| 2-Chloro-1-[3-(4-methylphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone | | toluenes | anticoronaviral agent |
| N-(1-dibutoxyphosphoryl-4-oxo-1-naphthalenyl)benzenesulfonamide | | naphthalenes | |
| 2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide | | aromatic ketone | |
| N-[3-(1-azepanylsulfonyl)phenyl]-4-oxo-1-benzopyran-2-carboxamide | | aromatic amide | |
| 8-[4-(4-fluorophenoxy)-3-nitrophenyl]-7-(2-hydroxyethyl)-3-(phenylmethyl)purine-2,6-dione | | aromatic ether | |
| 2-bromo-6-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-11-pyrido[2,1-b]quinazolinone | | pyridopyrimidine | |
| 1-(3-chlorophenyl)-3-pyridin-4-ylurea | | ureas | |
| 2-(4-bromophenyl)-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester | | quinolines | |
| tolcapone | tolcapone : Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.
Tolcapone: A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated. | 2-nitrophenols;
benzophenones;
catechols | antiparkinson drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor |
| 4-(1-azepanylsulfonyl)-N-[5-[(4-chlorophenyl)sulfamoyl]-2-hydroxyphenyl]benzamide | | benzamides | |
| 4-chloro-N-[3-(N-methylanilino)-1,4-dioxo-2-naphthalenyl]benzamide | | 1,4-naphthoquinones | |
| 4-(5-methyl-1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)benzoic acid 8-quinolinyl ester | | amidobenzoic acid | |
| 8-nitro-5-[3-(trifluoromethyl)-1-piperidinyl]isoquinoline | | isoquinolines | |
| N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine | | organonitrogen heterocyclic compound | |
| 7-chloro-N-(phenylmethyl)-4-quinolinamine | | aminoquinoline | |
| 1-(2,4-difluorophenyl)-3-[4-(2-pyridinyl)-2-thiazolyl]urea | | ureas | |
| 1-[2-(trifluoromethyl)phenyl]sulfonyl-4-piperidinecarboxylic acid [2-[(4-fluorophenyl)methylamino]-2-oxoethyl] ester | | sulfonamide | |
| N-[4-chloro-3-(4-morpholinylsulfonyl)phenyl]-4-(2-oxolanylmethoxy)benzamide | | benzamides | |
| 2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine | | piperidines | |
| 1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-[3-(dimethylamino)propyl]-1-ethylthiourea | | benzodioxine | |
| 1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thiourea | | indoles | |
| 4-[4-(4-acetylphenyl)-1-piperazinyl]-N-[3-(dimethylamino)propyl]-3-nitrobenzenesulfonamide | | aromatic ketone | |
| 2-[[4-(2-methoxyphenyl)sulfonyl-1-piperazinyl]sulfonyl]benzonitrile | | sulfonamide | |
| LSM-24516 | | pyranopyridine | |
| 2-(Chloroacetyl)-N,2-diphenylhydrazinecarboxamide | | ureas | anticoronaviral agent |
| 2-chloro-1-[1-(3-isoxazolyl)-2,5-dimethyl-3-pyrrolyl]ethanone | | aromatic ketone | |
| N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine | N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine : A member of the class of quinazolines that is quinazoline which is substituted by a pyridin-3-yl group and a (1-benzylpiperidin-4-yl)nitrilo group at positions 2 and 4, respectively. | aromatic amine;
piperidines;
pyridines;
quinazolines;
secondary amino compound;
tertiary amino compound | |
| N-(3-chloro-4-fluorophenyl)-2-[5-(dimethylsulfamoyl)-2-(ethylamino)anilino]acetamide | | amino acid amide | |
| 5-[(3-nitro-2-pyridinyl)thio]-N-prop-2-enyl-1,3,4-thiadiazol-2-amine | | aryl sulfide | |
| LSM-24595 | | amino acid amide | |
| N-(4-Nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide | | aromatic amide | anticoronaviral agent |
| [5-(4-fluorophenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[2-(3-pyridinyl)-1-piperidinyl]methanone | | pyrimidines | |
| 2-(4-methylphenoxy)-N-[2-[oxo(1-piperidinyl)methyl]phenyl]acetamide | | benzamides;
N-acylpiperidine | |
| 2-Chloro-1-[5-(furan-2-yl)-3-(5-methylfuran-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one | | pyrazolidines | anticoronaviral agent |
| 2-(2-chloro-1-oxoethyl)-3,4-dihydro-1H-isoquinoline-3-carboxylic acid methyl ester | | alpha-amino acid ester | |
| 5-carbamoyl-4-methyl-2-[[1-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]amino]-3-thiophenecarboxylic acid ethyl ester | | amino acid amide | |
| N-[(4-chlorophenyl)methyl]-2-[[[(2-fluorophenyl)methyl-(phenylmethyl)amino]-sulfanylidenemethyl]amino]acetamide | | amino acid amide | |
| 1-(7-methyloctyl)-3-[4-(4-morpholinylsulfonyl)phenyl]thiourea | | sulfonamide | |
| alsterpaullone | alsterpaullone : An organic heterotetracyclic compound that is 1,3-dihydro-2H-1-benzazepin-2-one which shares its 4-5 bond with the 3-2 bond of 5-nitro-1H-indole.
alsterpaullone: structure in first source | C-nitro compound;
caprolactams;
organic heterotetracyclic compound | anti-HIV-1 agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor |
| 5-[(5-bromo-2-hydroxyphenyl)-oxomethyl]-1-cyclohexyl-2-oxo-3-pyridinecarbonitrile | | aromatic ketone | |
| LSM-25964 | | organic heterotricyclic compound;
organooxygen compound | |
| N-[2-chloro-5-[ethyl(phenyl)sulfamoyl]phenyl]-2-[methyl-(1-methyl-4-piperidinyl)amino]acetamide | | amino acid amide | |
| 2-(4-fluoro-3-nitrophenyl)-4,4-dimethyl-5H-oxazole | | C-nitro compound | |
| 1-[4-chloro-3-(4-morpholinylsulfonyl)phenyl]-3-phenylurea | | sulfonamide | |
| 5-[(2,4-dichlorophenoxy)methyl]-N-[3,5-dimethyl-1-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-pyrazolyl]-2-furancarboxamide | | dichlorobenzene | |
| 4-[3-(2-chloro-1-oxoethyl)-2,5-dimethyl-1-pyrrolyl]-1,5-dimethyl-2-phenyl-3-pyrazolone | | pyrazoles;
ring assembly | |
| 4-tert-butyl-N-[3-[4-[3-[[(4-tert-butylphenyl)-oxomethyl]amino]propyl]-1-piperazinyl]propyl]benzamide | | benzamides | |
| N,N-diethylcarbamodithioic acid (2,2,2-trichloro-1-formamidoethyl) ester | | organonitrogen compound;
organosulfur compound | |
| 5-benzoyl-6-methyl-4-[4-(4-morpholinyl)phenyl]-3,4-dihydro-1H-pyrimidin-2-one | | morpholines | |
| N-(5-acetyl-4-methyl-2-thiazolyl)-2-(2,4-dichlorophenoxy)acetamide | | thiazoles | |
| apigenin | Chamomile: Common name for several daisy-like plants (MATRICARIA; TRIPLEUROSPERMUM; ANTHEMIS; CHAMAEMELUM) native to Europe and Western Asia, now naturalized in the United States and Australia. | trihydroxyflavone | antineoplastic agent;
metabolite |
| luteolin | | 3'-hydroxyflavonoid;
tetrahydroxyflavone | angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist |
| genistein | | 7-hydroxyisoflavones | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor |
| Euparotin acetate | | sesquiterpene lactone | |
| morin | morin : A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
morin: a light yellowish pigment found in the wood of old fustic (Chlorophora tinctoria) | 7-hydroxyflavonol;
pentahydroxyflavone | angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent |
| daidzein | | 7-hydroxyisoflavones | antineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite |
| caffeic acid phenethyl ester | phenethyl caffeate : An alkyl caffeate ester in which 2-phenylethyl is the alkyl component. | alkyl caffeate ester | anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent |
| 1,1-dimethylallyl caffeic acid ester | 1,1-dimethylallyl caffeic acid ester: structure given in first source | hydroxycinnamic acid | |
| rosmarinic acid | (R)-rosmarinic acid : A stereoisomer of rosmarinic acid having (R)-configuration.
rosmarinic acid : The 1-carboxy-2-(2,4-dihydroxyphenyl)ethyl ester of trans-caffeic acid.
rosmarinic acid: RN given refers to parent cpd; promote OT project | rosmarinic acid | geroprotector;
plant metabolite |
| astragalin | kaempferol 3-O-beta-D-glucoside : A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage.
kaempferol-3-O-glucoside: isolated from the pit of Mahkota dewa; structure in first source | beta-D-glucoside;
kaempferol O-glucoside;
monosaccharide derivative;
trihydroxyflavone | plant metabolite;
trypanocidal drug |
| cyclosporine | ramihyphin A: one of the metabolites produced by Fusarium sp. S-435; RN given refers to cpd with unknown MF | homodetic cyclic peptide | anti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite |
| phenylethyl 3-methylcaffeate | phenylethyl 3-methylcaffeate: a caffeic acid ester present in propolis, a natural resin produced by honey bees; structure given in first source | | |
| fenretinide | 4-hydroxyphenyl retinamide : A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.
Fenretinide: A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent. | monocarboxylic acid amide;
retinoid | antineoplastic agent;
antioxidant |
| N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide | | aromatic amide;
heteroarene | |
| 2-(2-furanylmethyl)-3-[[2-(3-pyridinyl)-3H-benzimidazol-5-yl]amino]-3H-isoindol-1-one | | isoindoles | |
| 2-[[4-methyl-5-[(2-oxo-1,3-benzothiazol-3-yl)methyl]-1,2,4-triazol-3-yl]thio]-N-(phenylmethyl)acetamide | | benzothiazoles | |
| 3-(4-chlorophenyl)-1-methyl-N-[3-(1-pyrrolidinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide | | pyrazoles;
ring assembly | |
| 3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one | | indoles | |
| cannabigerol | cannabigerol : A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.
cannabigerol: RN given refers to (E)-isomer; structure given in first source | phytocannabinoid;
resorcinols | anti-inflammatory agent;
antibacterial agent;
antioxidant;
appetite enhancer;
cannabinoid receptor agonist;
neuroprotective agent;
plant metabolite |
| ethyl caffeate | (E)-ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate: structure in first source
ethyl trans-caffeate : An ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. | alkyl caffeate ester;
ethyl ester;
hydroxycinnamic acid | anti-inflammatory agent;
antineoplastic agent;
metabolite |
| (2e)-3-phenyl-1-(2,3,4,5-tetrahydro-1,6-benzodioxocin-8-yl)prop-2-en-1-one | | | |
| Bucharaine | | quinolines | |
| serratin | serratin: isolated from the essential oil of Clerodendron serratum; structure in first source | neoflavonoid | |
| gamma-mangostin | gamma-mangostin : A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antitumour activity. | phenols;
xanthones | antineoplastic agent;
plant metabolite;
protein kinase inhibitor |
| 3,3'-diethylthiatricarbocyanine iodide, 3h-labeled | | | |
| 5233705 compound | | | |
| 10-hydroxy-3-methyl-8-pentyl-2,4-dihydro-1H-[1]benzopyrano[3,4-c]pyridin-5-one | | pyridochromene | |
| benzyl caffeate | benzyl caffeate: isolated from Liaoxi propolis | | |
| [4-(3-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | | piperazines;
pyridines | |
| 1-(3,4-dimethylphenyl)-4-(4-methyl-1-piperidinyl)phthalazine | | pyridazines;
ring assembly | |
| 2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone | | aromatic ketone | |
| 4-hydroxyderricin | 4-hydroxyderricin: from Angelica keiskei; RN given refers to (E)-isomer; structure in first source | chalcones | |
| kolavenic acid | kolavenic acid: from Polyalthia longifolia; structure given in first source; RN given refers to (1S-(1alpha(E),2beta,4abeta,8aalpha))-isomer; RN for cpd without isomeric designation not avail 3/92 | | |
| 1-(2-methoxy-5-methylphenyl)-3-pyridin-4-ylurea | | ureas | |
| scy-635 | | | |
| 2-chloro-N-(1-methyl-3-pyrazolyl)acetamide | | aromatic amide | |
| (3S)-2-(2-chloro-1-oxoethyl)-1,1-dimethyl-4,9-dihydro-3H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester | | harmala alkaloid | |
| N-(5-carbamoyl-2-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide | | aromatic amide | |
| N-[(2-chlorophenyl)methyl]-2-[7-oxo-3-(phenylmethyl)-6-triazolo[4,5-d]pyrimidinyl]acetamide | | triazolopyrimidines | |
| N-cyclohexyl-2-[[6-(4-ethoxyphenyl)-3-pyridazinyl]thio]acetamide | | pyridazines;
ring assembly | |
| 3-(ethylthio)-6-(2-furanyl)pyridazine | | aryl sulfide | |
| N-[3-(dimethylamino)propyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide | | benzothiazoles | |
| n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide | N-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide: a KCC2 cotransporter antagonist | pyridazines;
ring assembly | |
| 4-[3-(3-methylanilino)-2-imidazo[1,2-a]pyrimidinyl]phenol | | imidazoles | |
| N-(4-fluorophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide | | quinolines | |
| 2-(2,5-dichlorophenyl)sulfonyl-N-methyl-N-[(2-methylphenyl)methyl]ethanamine | | sulfonamide | |
| N-[2-(2-methoxyphenoxy)ethyl]-2,3-dihydro-1H-indene-5-carboxamide | | indanes | |
| 3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione | | diarylmethane | |
| alpha-solanine | | glycoalkaloid;
organic heterohexacyclic compound;
steroid saponin;
trisaccharide derivative | antineoplastic agent;
apoptosis inducer;
phytotoxin;
plant metabolite |
| N-[4-(1-adamantylsulfamoyl)phenyl]-4-bromo-1-methyl-3-pyrazolecarboxamide | | aromatic amide | |
| N-[3-(4-morpholinyl)propyl]-2,4-dioxo-3-(2-phenylethyl)-1H-quinazoline-7-carboxamide | | quinazolines | |
| 1-(3,5-dimethylphenyl)-3-(4-methyl-3-oxo-1,4-benzothiazin-6-yl)urea | | benzothiazine | |
| N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | | aromatic amide;
thiophenes | |
| n-phenacylthiazolium bromide | N-phenacylthiazolium bromide: structure given in first source | | |
| lissamine rhodamine b | lissamine rhodamine : An organic sodium salt having 4-[3,6-bis(diethylamino)xanthenium-9-yl]benzene-1,3-disulfonate as the counterion. | organic sodium salt | fluorescent probe;
fluorochrome;
histological dye |
| 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole | | | |
| a 443654 | A 443654: an Akt kinase inhibitor; structure in first source | indoles | |
| garcinone e | garcinone E: has potent cytotoxic effect against hepatocellular carcinoma cell lines; structure in first source | xanthones | |
| tafamidis | tafamidis : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole-6-carboxylic acid in which the hydrogen at position 2 is replaced by a 3,5-dichlorophenyl group. Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis.
tafamidis: may be effective in treating transthyretin amyloid polyneuropathy | 1,3-benzoxazoles;
dichlorobenzene;
monocarboxylic acid | central nervous system drug |
| 2-(4-methoxyphenyl)-1,2-benzothiazol-3-one | | benzothiazoles | |
| 2-(4-chlorophenyl)-1,2-benzothiazol-3-one | | benzothiazoles | |
| ditryptophenaline | ditryptophenaline: structure in first source | | |
| [4-(2-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone | | C-nitro compound | |
| 2-(3-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | | organonitrogen compound;
organooxygen compound | |
| 2-(4-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | | organonitrogen compound;
organooxygen compound | |
| 2-[(2-chloro-1-oxoethyl)-(2,2-dimethoxyethyl)amino]-2-(4-chlorophenyl)-N-cyclohexylacetamide | | organonitrogen compound;
organooxygen compound | |
| 2-[2-fluoro-5-(4-methyl-1-piperazinyl)-4-nitrophenyl]-3,4-dihydro-1H-isoquinoline | | piperazines | |
| 4-[3-(2-furanyl)-4-(3-nitrophenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid ethyl ester | | benzoate ester | |
| N-butyl-3-[1-[(2,5-dimethylphenyl)methyl]-2,4-dioxo-3-quinazolinyl]propanamide | | quinazolines | |
| 5-(1,3-benzodioxol-5-ylmethyl)-4-methyl-2-[[1-naphthalenyl(oxo)methyl]amino]-3-thiophenecarboxamide | | naphthalenecarboxamide | |
| 4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-ethylsulfonylthiazole | | isoquinolines | |
| [9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone | | aromatic ketone;
quinolines | |
| 2-(3-chlorophenyl)-1,2-benzothiazol-3-one | | benzothiazoles | |
| ortho-topolin riboside | ortho-topolin riboside: has antineoplastic activity; structure in first source | | |
| dehydrocurvularin | | macrolide | |
| malyngamide A | | dicarboximide | metabolite |
| 3-[(4-methoxyphenyl)methyl]-N-(3-methoxypropyl)-2,4-dioxo-1H-quinazoline-7-carboxamide | | quinazolines | |
| 4-chloro-N-[3-(3-methyl-1-piperidinyl)propyl]-2-thieno[3,2-c]quinolinecarboxamide | | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide | | pyrimidinecarboxamide | |
| (3-propan-2-yloxyphenyl)-[1-[(1-propan-2-yl-4-pyrazolyl)methyl]-3-piperidinyl]methanone | | aromatic ketone | |
| N-[2-(3,4-dimethoxyphenyl)ethyl]-2-[3-(4-fluorophenyl)-2,4-dioxo-1-thieno[3,2-d]pyrimidinyl]acetamide | | dimethoxybenzene | |
| 8-methyl-4-oxo-N-[3-(4-propyl-1-piperazinyl)propyl]-5H-thieno[3,2-c]quinoline-2-carboxamide | | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 1-(1-piperidinyl)-3-[4-[[2-[4-(trifluoromethyl)phenyl]ethylamino]methyl]phenoxy]-2-propanol | | (trifluoromethyl)benzenes | |
| [3-(1-methyl-2-pyrrolyl)-1H-pyrazol-5-yl]-[1-(2-pyridinyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methanone | | harmala alkaloid | |
| N-(2-furanylmethyl)-2-[[4-oxo-3-[3-(1-pyrrolidinyl)propyl]-[1]benzothiolo[3,2-d]pyrimidin-2-yl]thio]acetamide | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
| 2-(3,5-dimethyl-1-pyrazolyl)-1-[3-[oxo-(3-propan-2-yloxyphenyl)methyl]-1-piperidinyl]ethanone | | aromatic ketone | |
| 1-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)-4-pyrazolyl]methyl]-4-methoxypiperidine | | pyrazoles;
ring assembly | |
| N-[[3-(3-methylphenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]-3-(1-pyrazolyl)-1-propanamine | | pyrazoles;
ring assembly | |
| [1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol | | methylindole | |
| [1-[(6-chloro-2H-1-benzopyran-3-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol | | 1-benzopyran | |
| [1-[(1,2-dimethyl-3-indolyl)methyl]-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanol | | piperidines | |
| 1-(5-isoquinolinylmethyl)-4-[(3-methoxyphenyl)methyl]-4-piperidinecarboxylic acid ethyl ester | | piperidines | |
| 5-[[1-(2-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methyl]-2-methylthiazole | | harmala alkaloid | |
| [1-[[1-(5-chloro-2-pyridinyl)-2-pyrrolyl]methyl]-3-piperidinyl]-(2,4-dimethoxyphenyl)methanone | | aromatic ketone | |
| 1-[[3-(2-fluorophenyl)-1-methyl-4-pyrazolyl]methyl]-3-propoxypiperidine | | pyrazoles;
ring assembly | |
| 1-(2-chloro-4-methylphenyl)-3-[[1-[(3-chlorophenyl)methyl]-4-piperidinyl]methyl]urea | | piperidines | |
| N-[3-(1-azepanyl)propyl]-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxamide | | quinazolines | |
| 4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]piperidine | | piperidines | |
| N-(4-ethoxyphenyl)-2-[4-[2-(methylthio)ethyl]-2,5-dioxo-1-imidazolidinyl]acetamide | | imidazolidine-2,4-dione | |
| 2-[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)amino]-1-(4-nitrophenyl)ethanol | | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound;
thienopyrimidine | |
| 5-chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(phenylmethyl)sulfonyl-4-pyrimidinecarboxamide | | pyrimidinecarboxamide | |
| 5-chloro-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-[(4-fluorophenyl)methylsulfonyl]-4-pyrimidinecarboxamide | | pyrimidinecarboxamide | |
| (5S)-1-(4-cyclohexylbutyl)-5-phenyl-4,5-dihydroimidazol-2-amine | | benzenes | |
| (5R)-1-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-5-butyl-4,5-dihydroimidazol-2-amine | | (trifluoromethyl)benzenes | |
| (2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester | | aromatic amide;
tert-butyl ester | |
| 1-[1-(4-butan-2-ylphenyl)ethyl]-3-[(4-fluorophenyl)methyl]thiourea | | monoterpenoid | |
| N-butyl-4-(phenylmethyl)-1-piperidinecarbothioamide | | piperidines | |
| 2-(2,5-dichlorophenoxy)-1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-butanone | | azaspiro compound | |
| 1-[(4-fluorophenyl)methyl]-3-[1-(4-propan-2-ylphenyl)propyl]thiourea | | monoterpenoid | |
| 1-(3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)thiourea | | thioureas | |
| N-[2-(2,5-dimethoxyphenyl)ethyl]-4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazine-6-carboxamide | | benzothiazine | |
| 5-fluoro-2-phenyl-1,2-benzothiazol-3-one | | benzothiazoles | |
| 2-(2-fluorophenyl)-1,2-benzothiazol-3-one | | benzothiazoles | |
| 3-[1-[[1-(4-methylphenyl)cyclopropyl]-oxomethyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-one | | acetamides | |
| nuclear fast red | nuclear fast red : An organic sodium salt that is the monosodium salt of 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid. It forms bright red lakes with calcium and is a useful red nuclear staining lake with aluminum.
nuclear fast red: structure in first source; do not confuse with nuclear fast red (basic dye) | organic sodium salt | fluorochrome;
histological dye |
| fractals | (3S,5R)-fluvastatin sodium : An organic sodium salt resulting from the replacement of the proton from the carboxy group of (3S,5R)-fluvastatin by a sodium ion. | organic sodium salt;
statin (synthetic) | |
| 2-[[2-(2-cyanophenoxy)-1-oxoethyl]amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester | | thienopyridine | |
| 4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine | dafadine A : An N-acylpiperidine obtained by formal condensation of the carboxy group of 5-[(2,6-dimethylphenoxy)methyl]-1,2-oxazole-3-carboxylic acid with the secondary amino group of 4-(pyridin-4-yl)piperidine. | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines | geroprotector;
P450 inhibitor |
| 1-[(2,3-dimethyl-4-imidazolyl)methyl]-N-[4-(2-furanyl)phenyl]-3-piperidinecarboxamide | | anilide | |
| N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamide | | pyrazoles;
ring assembly | |
| (2R)-N2-[2-(4-bicyclo[2.2.1]heptanyl)ethyl]-N1-[(2R,3R)-3-methyl-1-(methylamino)pentan-2-yl]hexane-1,2-diamine | | monoterpenoid | |
| 4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenol | | amphetamines | |
| (2R)-3-[[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]amino]-2-[2-[3-(trifluoromethyl)phenyl]ethylamino]-1-propanol | | (trifluoromethyl)benzenes | |
| N-[2-[1-[(4-methoxy-3-methylphenyl)methyl]-4-piperidinyl]-3-pyrazolyl]-4-phenylbutanamide | | piperidines | |
| N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-4-methyl-5-thiadiazolecarboxamide | | pyrazoles;
ring assembly | |
| [2-(2-methoxyethyl)-1-piperidinyl]-[5-[[4-(1,2,4-triazol-1-yl)phenoxy]methyl]-3-isoxazolyl]methanone | | triazoles | |
| N-methyl-N-(3-pyridinylmethyl)-5-(5,6,7,8-tetrahydronaphthalen-2-yloxymethyl)-3-isoxazolecarboxamide | | tetralins | |
| 1-[(1-ethyl-3-methyl-4-pyrazolyl)methyl]-N-[4-(2-fluorophenoxy)phenyl]-4-piperidinecarboxamide | | aromatic ether | |
| 2-[[[4-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester | | N-acyl-amino acid;
tert-butyl ester | |
| 5-[(3,4-dimethylphenoxy)methyl]-N-methyl-N-(4-oxanylmethyl)-3-isoxazolecarboxamide | | aromatic ether | |
| 2-(2,6-dimethylphenoxy)-N-[2-(1-piperidinyl)phenyl]acetamide | | piperidines | |
| (5S)-1-heptyl-5-(2-methylpropyl)-N-phenyl-4,5-dihydroimidazol-2-amine | | substituted aniline | |
| 4-(4-acetyloxyphenyl)benzoic acid [2-[[2-(2-chloroanilino)-2-oxoethyl]-methylamino]-2-oxoethyl] ester | | biphenyls | |
| ucph 101 | 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile: structure in first source | | |
| 2-(3-oxo-1,2-benzothiazol-2-yl)-N-phenylacetamide | | benzothiazoles | |
| 3-furanyl-[4-[5-(2-furanyl)-2-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-1-piperazinyl]methanone | | N-arylpiperazine | |
| mk-7246 | | | |
| 4-hydroxy-1-(2-methylpropyl)-2-oxo-N-(2-sulfamoylphenyl)-3-quinolinecarboxamide | | aromatic amide | |
| 3-benzyl-4-hydroxyquinolin-2(1H)-one | | hydroxyquinoline;
quinolone | |
| idarucizumab | | | |
| kf38789 | KF38789: a non-carbohydrate low MW cpd that Inhibits P-selectin specific cell adhesion; structure in first source | | |
| 6-[5-[[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]methyl]-2-oxo-1,3-dihydroimidazol-4-yl]-6-oxohexanoic acid ethyl ester | | pyrimidines | |
| azaguanine | 8-azaguanine : A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
Azaguanine: One of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. | nucleobase analogue;
triazolopyrimidines | antimetabolite;
antineoplastic agent;
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor |
| N-tert-butyl-3-(3-tert-butyl-1-methyl-7-oxo-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxybenzenesulfonamide | | sulfonamide | |
| salicylaldehyde thiosemicarbazone | salicylaldehyde thiosemicarbazone: structure given in first source | | |
| 7-methyl-2-[(4-methyl-6-phenyl-2-pyrimidinyl)amino]-1H-quinazolin-4-one | | pyrimidines | |
| N-[4-[2-[3-(dimethylsulfamoyl)anilino]-6H-1,3,4-thiadiazin-5-yl]phenyl]acetamide | | sulfonamide | |
| 1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl ester | | aromatic amide | |
| pyridoxal 4-methoxybenzoyl hydrazone | pyridoxal 4-methoxybenzoyl hydrazone: structure given in first source | | |
| 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-1H-pyrimidin-4-one | | quinazolines | |
| 2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide | | pyrimidines | |
| 5-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole | | pyrazoles;
ring assembly | |