trifluoperazine has been researched along with Carbon Tetrachloride Poisoning in 3 studies
Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trifluoperazine (TFP) (50 mg/kg ip) administration to rats 6 or 10 hr after CCl4 (1 ml/kg ip in olive oil) significantly prevented liver necrosis but not fatty liver caused by the hepatotoxin at 24 hr as evidenced by either histology or electron microscopy." | 3.67 | Further studies on the late preventive effects of the anticalmodulin trifluoperazine on carbon tetrachloride-induced liver necrosis. ( Bernacchi, AS; Castro, JA; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Fernández, G; Villarruel, MC, 1988) |
| "Promethazine does not inhibit these systems to the same extent as it does the NADPH(2)-ADP-Fe(2+) lipid-peroxidation system." | 1.25 | The inhibitory effects in vitro of phenothiazines and other drugs on lipid-peroxidation systems in rat liver microsomes, and their relationship to the liver necrosis produced by carbon tetrachloride. ( Slater, TF, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernacchi, AS | 2 |
| Fernández, G | 1 |
| Villarruel, MC | 1 |
| de Ferreyra, EC | 2 |
| de Castro, CR | 1 |
| de Fenos, OM | 1 |
| Castro, JA | 2 |
| Slater, TF | 1 |
3 other studies available for trifluoperazine and Carbon Tetrachloride Poisoning
| Article | Year |
|---|---|
Further studies on the late preventive effects of the anticalmodulin trifluoperazine on carbon tetrachloride-induced liver necrosis.
Topics: Animals; Calcium; Calmodulin; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury | 1988 |
Increased glutathione (GSH) content in livers of control and carbon tetrachloride poisoned rats treated with the anticalmodulin drug trifluoperazine (TFP).
Topics: Animals; Calmodulin; Carbon Tetrachloride Poisoning; Glutathione; Liver; Male; Rats; Rats, Inbred St | 1986 |
The inhibitory effects in vitro of phenothiazines and other drugs on lipid-peroxidation systems in rat liver microsomes, and their relationship to the liver necrosis produced by carbon tetrachloride.
Topics: Adenine Nucleotides; Animals; Animals, Newborn; Carbon Tetrachloride Poisoning; Chemical and Drug In | 1968 |