Page last updated: 2024-08-05 12:14:38

fluorenes

An ortho-fused polycyclic arene in which the skeleton is composed of two benzene rings ortho-fused to cyclopentane.

ChEBI ID: 24059

Members (22)

MemberDefinitionRole
2-(dimethylsulfamoylamino)-9H-fluorene2-(dimethylsulfamoylamino)-9H-fluorene
2-[[(4-ethoxyphenyl)-oxomethyl]amino]acetic acid [2-(9H-fluoren-3-yl)-2-oxoethyl] ester2-[[(4-ethoxyphenyl)-oxomethyl]amino]acetic acid [2-(9H-fluoren-3-yl)-2-oxoethyl] ester
2-[[5-(3-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(9H-fluoren-2-yl)ethanone2-[[5-(3-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(9H-fluoren-2-yl)ethanone
2-[4-(9H-fluoren-9-yl)-1-piperazinyl]-N-(4-methoxyphenyl)acetamide2-[4-(9H-fluoren-9-yl)-1-piperazinyl]-N-(4-methoxyphenyl)acetamide
2-{[(9H-9-fluorenylmethoxy)carbonyl]amino}benzoic acid2-{[(9H-9-fluorenylmethoxy)carbonyl]amino}benzoic acid
2-bromo-N-(9-fluorenylideneamino)benzamide2-bromo-N-(9-fluorenylideneamino)benzamide
2-butoxy-7-hydroxy-9-fluorenone2-butoxy-7-hydroxy-9-fluorenone
2-hydroxyfluorene2-Hydroxyfluorene
4-(9H-fluoren-9-yl)-N-phenyl-1-piperazinecarboxamide4-(9H-fluoren-9-yl)-N-phenyl-1-piperazinecarboxamide
4-acetylaminofluoreneA member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is replaced by a 9H-fluoren-4-yl group.4-acetylaminofluorene
9-hydroxyiminofluorene-2,7-disulfonamide9-hydroxyiminofluorene-2,7-disulfonamide
9-oxo-3-fluorenecarboxylic acid (phenylmethyl) ester9-oxo-3-fluorenecarboxylic acid (phenylmethyl) ester
9,9-bis(4-hydroxyphenyl)fluoreneA member of the class of fluorenes that is 9H-fluorene in which both of the hydrogens at position 9 have been replaced by p-hydroxyphenyl groups.9,9-bis(4-hydroxyphenyl)fluorene
bms201038A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.lomitapide
indecainideindecainide
ledipasvirA benzimidazole derivative that is used in combination with sofosbuvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection.ledipasvir
lumefantrineA member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria.lumefantrine
N-(3-chlorophenyl)-4-(9H-fluoren-9-yl)-1-piperazinecarboxamideN-(3-chlorophenyl)-4-(9H-fluoren-9-yl)-1-piperazinecarboxamide
N-(4-methoxyphenyl)carbamic acid (9-fluorenylideneamino) esterN-(4-methoxyphenyl)carbamic acid (9-fluorenylideneamino) ester
N-fluorenylacetamideN-fluorenylacetamide
N2,N7-bis(2,5-dimethylphenyl)-9H-fluorene-2,7-disulfonamideN2,N7-bis(2,5-dimethylphenyl)-9H-fluorene-2,7-disulfonamide
ngb 2904N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide

Research

Studies (1,063)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199025 (2.35)18.7374
1990's40 (3.76)18.2507
2000's161 (15.15)29.6817
2010's635 (59.74)24.3611
2020's202 (19.00)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials208 (17.28%)5.53%
Reviews133 (11.05%)6.00%
Case Studies79 (6.56%)4.05%
Observational27 (2.24%)0.25%
Other757 (62.87%)84.16%