trifluoperazine has been researched along with Neuroleptic Malignant Syndrome in 19 studies
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A case is reported in which neuroleptic treatment was successfully reintroduced with molindone after previous bouts of neuroleptic malignant syndrome (NMS) with trifluoperazine and thioridazine." | 7.67 | Reinstitution of neuroleptic treatment with molindone in a patient with a history of neuroleptic malignant syndrome. ( Slack, T; Stoudemire, A, 1989) |
| "Neuroleptic-induced catatonia is reported in an adolescent patient who responded successfully to lorazepam." | 4.78 | Neuroleptic-induced catatonia as a stage in the progression toward neuroleptic malignant syndrome. ( Woodbury, MA; Woodbury, MM, 1992) |
| "A patient developed neuroleptic malignant syndrome after a single dose of venlafaxine with trifluoperazine treatment." | 3.70 | Neuroleptic malignant syndrome after venlafaxine. ( Atkin, SL; Nimmagadda, SR; Ryan, DH, 2000) |
| "A 50-year-old man presented with hyperosmolar non-ketotic diabetic coma associated with the neuroleptic malignant syndrome (NMS) after intramuscular treatment with haloperidol." | 3.68 | Neuroleptic malignant syndrome presenting as hyperosmolar non-ketotic diabetic coma. ( Balzan, M; Cacciottolo, JM, 1992) |
| " A case is reported in which neuroleptic treatment was successfully reintroduced with molindone after previous bouts of neuroleptic malignant syndrome (NMS) with trifluoperazine and thioridazine." | 3.67 | Reinstitution of neuroleptic treatment with molindone in a patient with a history of neuroleptic malignant syndrome. ( Slack, T; Stoudemire, A, 1989) |
| "The authors report a case of unequivocal Neuroleptic Malignant Syndrome, in which the patient was successfully rechallenged with a different potent neuroleptic in substantial dosage during the recovery phase." | 1.28 | Use of neuroleptics after an episode of neuroleptic malignant syndrome. ( Lipman, E; Padgett, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 13 (68.42) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lappa, A | 1 |
| Podestà , M | 1 |
| Capelli, O | 1 |
| Castagna, A | 1 |
| Di Placido, G | 1 |
| Alampi, D | 1 |
| Semeraro, F | 1 |
| Wijeratne, C | 1 |
| Kausar, SA | 1 |
| Harvey, A | 1 |
| Mukherjee, D | 1 |
| Nimmagadda, SR | 1 |
| Ryan, DH | 1 |
| Atkin, SL | 1 |
| Renwick, DS | 1 |
| Chandraker, A | 1 |
| Bannister, P | 1 |
| Woodbury, MM | 1 |
| Woodbury, MA | 1 |
| Balzan, M | 1 |
| Cacciottolo, JM | 1 |
| Velamoor, VR | 2 |
| van Harten, PN | 1 |
| Kemperman, CJ | 2 |
| Coulter, F | 1 |
| Corrigan, FM | 1 |
| Dalkin, T | 1 |
| Lee, AS | 1 |
| van den Hoofdakker, RH | 1 |
| Montalto, M | 1 |
| Frankenburg, FR | 1 |
| Slack, T | 1 |
| Stoudemire, A | 1 |
| Padgett, R | 1 |
| Lipman, E | 1 |
| Lavie, CJ | 1 |
| Ventura, HO | 1 |
| Walker, G | 1 |
| Merry, SN | 1 |
| Werry, JS | 1 |
| Merry, AF | 1 |
| Birchall, N | 1 |
1 review available for trifluoperazine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic-induced catatonia as a stage in the progression toward neuroleptic malignant syndrome.
Topics: Adolescent; Catatonia; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Male; Neuroleptic | 1992 |
18 other studies available for trifluoperazine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Successful treatment of a complicated case of neuroleptic malignant syndrome.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Dantrolene; Disseminated Intravascular Coagulatio | 2002 |
Neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Aged; Diagnosis, Differential; Electroconvulsive Therapy; Female; Fever; Humans; Neuroleptic Maligna | 1996 |
Fits and starts.
Topics: Aged; Antipsychotic Agents; Female; Humans; Neuroleptic Malignant Syndrome; Schizophrenia; Seizures; | 1998 |
Neuroleptic malignant syndrome after venlafaxine.
Topics: Adult; Antidepressive Agents, Second-Generation; Cyclohexanols; Dopamine Antagonists; Drug Interacti | 2000 |
Missed neuroleptic malignant syndrome.
Topics: Aged; Creatine Kinase; Depressive Disorder; Diagnostic Errors; Escherichia coli Infections; Female; | 1992 |
Neuroleptic malignant syndrome presenting as hyperosmolar non-ketotic diabetic coma.
Topics: Body Temperature Regulation; Combined Modality Therapy; Depressive Disorder; Diagnosis, Differential | 1992 |
NMS complicated by diazepam.
Topics: Aged; Coma; Diazepam; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Risk Factors; Schiz | 1992 |
Organic amnestic disorder: a long-term sequel after neuroleptic malignant syndrome.
Topics: Adult; Amnesia; Cerebral Cortex; Electroencephalography; Female; Follow-Up Studies; Humans; Infant, | 1991 |
Carbamazepine and NMS.
Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Neuroleptic Malignant Syndro | 1991 |
Carbamazepine and forme fruste neuroleptic malignant syndrome.
Topics: Bipolar Disorder; Body Temperature; Carbamazepine; Drug Overdose; Drug Therapy, Combination; Female; | 1990 |
Neuroleptic malignant syndrome (NMS): challenge with zuclopenthixol and follow-up--a case report.
Topics: Adult; Clopenthixol; Dyskinesia, Drug-Induced; Electroencephalography; Female; Haloperidol; Humans; | 1990 |
A malignant reaction to trifluoperazine (Stelazine).
Topics: Adult; Diagnosis, Differential; Humans; Male; Neuroleptic Malignant Syndrome; Trifluoperazine | 1990 |
Neuroleptic malignant syndrome.
Topics: Adult; Diazepam; Drug Therapy, Combination; Humans; Lithium; Male; Neuroleptic Malignant Syndrome; R | 1990 |
Dantrolene sodium in neuroleptic malignant syndrome and hepatic impairment.
Topics: Adult; Dantrolene; Humans; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Neuroleptic Malig | 1990 |
Reinstitution of neuroleptic treatment with molindone in a patient with a history of neuroleptic malignant syndrome.
Topics: Adolescent; Bipolar Disorder; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Ther | 1989 |
Use of neuroleptics after an episode of neuroleptic malignant syndrome.
Topics: Adolescent; Dibenzoxazepines; Drug Therapy, Combination; Humans; Loxapine; Male; Methotrimeprazine; | 1989 |
Neuroleptic malignant syndrome: three episodes with different drugs.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Humans; Neuroleptic Malignant Synd | 1986 |
The neuroleptic malignant syndrome in an adolescent.
Topics: Adolescent; Diagnosis, Differential; Humans; Male; Malignant Hyperthermia; Neuroleptic Malignant Syn | 1986 |