trifluoperazine has been researched along with Triple Negative Breast Neoplasms in 2 studies
Triple Negative Breast Neoplasms: Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trifluoperazine (TFP) is an approved antipsychotic drug with good bioavailability in brain and had shown anticancer effect in several types of cancer." | 1.48 | The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis. ( Feng, Z; Gao, T; Hu, X; Lei, Q; Peng, C; Ran, Z; Wang, Q; Wang, R; Xia, Y; Xie, Z; Xu, F; Xue, Q; Yang, N; Yang, Y; Yu, L; Zeng, Z, 2018) |
| "Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer." | 1.43 | Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo. ( Berek, JS; Chung, YM; Hu, MC; Ma, J; Park, SH; Yang, Q, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, Z | 1 |
| Xia, Y | 1 |
| Gao, T | 1 |
| Xu, F | 1 |
| Lei, Q | 1 |
| Peng, C | 1 |
| Yang, Y | 1 |
| Xue, Q | 1 |
| Hu, X | 1 |
| Wang, Q | 1 |
| Wang, R | 1 |
| Ran, Z | 1 |
| Zeng, Z | 1 |
| Yang, N | 1 |
| Xie, Z | 1 |
| Yu, L | 1 |
| Park, SH | 1 |
| Chung, YM | 1 |
| Ma, J | 1 |
| Yang, Q | 1 |
| Berek, JS | 1 |
| Hu, MC | 1 |
2 other studies available for trifluoperazine and Triple Negative Breast Neoplasms
| Article | Year |
|---|---|
The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
Topics: Animals; Antipsychotic Agents; Apoptosis; Brain; Brain Neoplasms; Caspase 3; Cell Cycle Checkpoints; | 2018 |
Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo.
Topics: Animals; Apoptosis; Bepridil; Breast Neoplasms; Cell Nucleus; Dopamine; Female; Forkhead Box Protein | 2016 |