forkhead box protein O1 inhibitor

Any inhibitor that acts on forkhead box protein O1 (FOXO1).

ChEBI ID: 145807

Members (1)

Member	Definition	Class
as 1842856	A quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations.	AS1842856

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
Forkhead box protein O1	Homo sapiens (human)	IC50	0.0330	1	1