Hypochondriacal Neuroses

Preoccupation with the fear of having, or the idea that one has, a serious disease based on the person's misinterpretation of bodily symptoms. (APA, DSM-IV)

Synonym
Hypochondriacal Neuroses
Hypochondriasis
Neurosis, Hypochondriacal

Excerpt	Reference
"Hypochondriasis is shown to be more strongly associated with early father death, while Paranoia is associated equally with mother and father death."	( Birtchnell, J, 1978)
"Hypochondriasis is a disorder for which there are no established effective treatments."	( Fallon, BA; Hollander, E; Javitch, JA; Liebowitz, MR, 1991)

Excerpt	Reference
"The prognosis of treated hypochondriasis is good in a substantial proportion of patients."	( Kellner, R, 1985)
"Before treatment, IBQ hypochondriasis scores were similar to those of a group of hypochondriacal psychiatric patients."	( Clancy, J; Noyes, R; O'Gorman, TW; Reich, J, 1986)
"Fifty-seven patients with hypochondriasis were enrolled: 12 discontinued during the placebo run-in, and 45 were randomized to either fluoxetine or placebo for 12 weeks (acute treatment)."	( Cheng, J; Fallon, BA; Liebowitz, MR; Petkova, E; Sanchez-Lacay, A; Schneier, F; Skritskaya, N; Vermes, D, 2008)
"Prior studies of hypochondriasis demonstrated benefits for pharmacotherapy and for cognitive-behavioral therapy (CBT)."	( Ahern, DK; Barsky, AJ; Fallon, BA; Pavlicova, M; Skritskya, N; Slavov, I, 2017)
"Patients with DSM-IV hypochondriasis (N=195) were randomly assigned to one of four treatments-placebo, CBT, fluoxetine, or joint treatment with both fluoxetine and CBT."	( Ahern, DK; Barsky, AJ; Fallon, BA; Pavlicova, M; Skritskya, N; Slavov, I, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	182 (72.22)	23.3326
1990's	23 (9.13)	12.5806
2000's	29 (11.51)	18.1394
2010's	18 (7.14)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
carbamates	low	1	0
dihydroxyphenylalanine	low	1	0
nitrous oxide	low	1	0
normetanephrine	medium	1	1
vanilmandelic acid	medium	1	1
3,4-methylenedioxyamphetamine	low	2	0
alprazolam	low	2	0
dan 2163	low	1	0
amitriptyline	medium	10	4
amobarbital	low	1	0
amoxapine	low	1	0
aniracetam	low	1	0
aspirin	low	3	0
bupivacaine	low	1	0
carbamazepine	low	1	0
chlordiazepoxide	medium	5	2
chlormezanone	medium	1	1
chlorpromazine	low	1	0
citalopram	medium	4	2
clomipramine	low	5	0
clonazepam	low	1	0
amphetamine	low	1	0
diazepam	medium	11	4
valproic acid	low	2	0
doxepin	medium	5	2
ethosuximide	low	1	0
fluphenazine	medium	3	1
fluoxetine	medium	7	3
flurazepam	medium	2	1
gabapentin	low	1	0
haloperidol	medium	3	1
phenelzine	medium	2	1
imipramine	medium	12	5
isocarboxazid	low	1	0
lorazepam	medium	1	1
meprobamate	low	2	0
mianserin	medium	2	1
mirtazapine	low	1	0
moclobemide	medium	1	1
nialamide	low	2	0
oxazepam	low	2	0
oxyphenbutazone	low	1	0
perphenazine	medium	1	1
pirenzepine	low	2	0
prazepam	medium	1	1
procaine	low	1	0
prochlorperazine	low	1	0
propranolol	medium	2	1
protriptyline	low	1	0
risperidone	low	3	0
succinylcholine	low	1	0
sulpiride	medium	3	1
thioridazine	medium	2	1
tofisopam	low	1	0
trifluoperazine	low	3	0
trihexyphenidyl	low	1	0
trimeprazine	low	1	0
trimipramine	medium	1	1
prednisolone	low	1	0
lysergic acid diethylamide	low	1	0
reserpine	low	2	0
biguanides	medium	1	1
levodopa	low	1	0
tyrosine	low	1	0
methacholine chloride	low	1	0
phenylalanine	medium	1	1
colchicine	low	1	0
tryptophan	low	2	0
phenothiazine	low	1	0
quinuclidines	low	2	0
cyclohexanol	medium	1	1
thiophenes	low	2	0
1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt	low	1	0
methohexital	low	1	0
opipramol	low	3	0
fluorobenzenes	medium	1	1
psilocybin	low	1	0
methamphetamine	low	1	0
lithium carbonate	low	1	0
pimozide	medium	39	2
flupenthixol	low	1	0
cyclazocine	medium	1	1
tranylcypromine	low	2	0
valnoctamide	low	1	0
trolamine salicylate	low	2	0
bromocriptine	low	1	0
phenyl acetate	medium	2	1
cetylpyridinium chloride anhydrous	low	12	0
4-methoxyamphetamine	low	13	0
phenazepam	medium	2	1
paroxetine	medium	7	4
fomesafen	low	1	0
fenoxycarb	low	1	0
aripiprazole	low	1	0
duloxetine hydrochloride	low	2	0
cyamemazine	low	1	0
venlafaxine hydrochloride	medium	1	1
sertraline	low	2	0
methotrimeprazine	low	1	0
melamine phosphate	medium	1	1
atropine	low	3	0
ramelteon	low	1	0
sesquiterpenes	low	1	0
lithium	low	3	0
freedom	low	1	0
oxymetholone	low	1	0
humulene	low	2	0
dothiepin hydrochloride	medium	2	1
morphine	low	1	0
fluvoxamine	low	1	0
heroin	low	1	0
paliperidone palmitate	low	1	0
thiocolchicoside	low	1	0
sodium ethylxanthate	medium	6	1
s-adenosylmethionine	medium	1	1
quetiapine fumarate	low	2	0
piperidines	medium	1	1
ascorbic acid	low	1	0
clozapine	low	2	0
olanzapine	low	6	0
eye	low	2	0
ego	low	10	0

Protein Targets (914)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	26	4	30
5-hydroxytryptamine receptor 2A	0	27	5	32
5-hydroxytryptamine receptor 1A	0	38	5	44
Sodium-dependent noradrenaline transporter	0	40	6	46
Sodium-dependent dopamine transporter	0	18	1	19
5-hydroxytryptamine receptor 1B	0	28	3	31
5-hydroxytryptamine receptor 1D	0	12	3	15
5-hydroxytryptamine receptor 1F	0	12	3	15
5-hydroxytryptamine receptor 2B	0	24	5	29
5-hydroxytryptamine receptor 6	0	5	3	8
Sodium-dependent serotonin transporter	0	44	9	53
Sodium-dependent serotonin transporter	0	16	2	18
5-hydroxytryptamine receptor 7	0	13	3	16
5-hydroxytryptamine receptor 5A	0	5	3	8
5-hydroxytryptamine receptor 5B	0	5	3	8
5-hydroxytryptamine receptor 3A	0	7	3	10
Sodium-dependent dopamine transporter	0	28	4	32
5-hydroxytryptamine receptor 4	0	5	3	8
5-hydroxytryptamine receptor 3B	0	7	3	10
TDP1 protein	49	0	0	49
AR protein	46	0	0	46
glucocorticoid receptor [Homo sapiens]	40	0	0	40
pregnane X nuclear receptor	35	0	0	35
estrogen nuclear receptor alpha	48	0	0	48
peroxisome proliferator activated receptor gamma	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	25	0	0	25
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
thyroid hormone receptor beta isoform 2	36	0	0	36
nuclear receptor ROR-gamma isoform 1	14	0	0	14
lamin isoform A-delta10	33	0	0	33
Gamma-aminobutyric acid receptor subunit pi	20	10	2	32
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	9	4	13
Gamma-aminobutyric acid receptor subunit beta-1	20	10	2	32
Gamma-aminobutyric acid receptor subunit delta	20	10	2	32
Gamma-aminobutyric acid receptor subunit gamma-2	0	9	2	11
Gamma-aminobutyric acid receptor subunit gamma-2	20	10	3	33
Gamma-aminobutyric acid receptor subunit alpha-5	20	10	2	32
Gamma-aminobutyric acid receptor subunit alpha-3	20	10	2	32
Gamma-aminobutyric acid receptor subunit gamma-1	20	10	2	32
Gamma-aminobutyric acid receptor subunit alpha-2	20	10	2	32
Gamma-aminobutyric acid receptor subunit alpha-4	20	10	2	32
Gamma-aminobutyric acid receptor subunit gamma-3	20	10	2	32
Gamma-aminobutyric acid receptor subunit alpha-6	20	10	2	32
Cholecystokinin receptor type A	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	9	4	13
Gamma-aminobutyric acid receptor subunit alpha-3	0	9	3	12
Gamma-aminobutyric acid receptor subunit alpha-2	0	9	3	12
Gamma-aminobutyric acid receptor subunit beta-2	0	8	2	10
Gamma-aminobutyric acid receptor subunit alpha-1	20	11	3	34
Gamma-aminobutyric acid receptor subunit beta-3	20	10	2	32
Gamma-aminobutyric acid receptor subunit beta-2	20	10	3	33
Cholecystokinin receptor type A	0	3	0	3
GABA theta subunit	20	10	2	32
ATPase family AAA domain-containing protein 5	16	0	0	16
Ataxin-2	37	0	0	37
Gamma-aminobutyric acid receptor subunit epsilon	20	10	2	32
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
thioredoxin reductase	28	0	0	28
USP1 protein, partial	24	0	0	24
NFKB1 protein, partial	14	0	0	14
GLS protein	27	0	0	27
cytochrome P450 family 3 subfamily A polypeptide 4	37	0	0	37
cytochrome P450 2D6	32	0	0	32
arylsulfatase A	19	0	0	19
cytochrome P450 2D6 isoform 1	23	0	0	23
D(1A) dopamine receptor	29	0	0	29
chromobox protein homolog 1	30	0	0	30
atrial natriuretic peptide receptor 2 precursor	18	0	0	18
serine/threonine-protein kinase mTOR isoform 1	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 1	33	0	0	33
muscarinic acetylcholine receptor M1	23	0	0	23
Solute carrier family 22 member 1	0	13	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15B	14	0	0	14
ATP-binding cassette sub-family C member 3	0	33	0	33
Multidrug resistance-associated protein 4	0	33	0	33
Voltage-dependent L-type calcium channel subunit alpha-1F	0	10	0	10
5-hydroxytryptamine receptor 4	0	40	0	40
Bile salt export pump	0	50	0	50
Albumin	0	0	10	10
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	33	0	33
Muscarinic acetylcholine receptor M2	0	34	3	40
Muscarinic acetylcholine receptor M4	0	34	2	38
Muscarinic acetylcholine receptor M1	0	12	1	15
Muscarinic acetylcholine receptor M3	0	12	1	15
Muscarinic acetylcholine receptor M4	0	12	1	15
Muscarinic acetylcholine receptor M5	0	14	1	17
Muscarinic acetylcholine receptor M5	0	35	1	38
Alpha-2A adrenergic receptor	0	36	3	40
Muscarinic acetylcholine receptor M2	0	12	1	16
Muscarinic acetylcholine receptor M1	0	37	5	46
Angiotensin-converting enzyme	0	28	0	28
D(2) dopamine receptor	0	39	6	52
Alpha-2B adrenergic receptor	0	33	2	36
Alpha-2C adrenergic receptor	0	34	2	37
Muscarinic acetylcholine receptor M3	0	37	3	42
D(1A) dopamine receptor	0	30	1	34
D(1B) dopamine receptor	0	8	0	11
UDP-glucuronosyltransferase 1A4	0	0	0	6
Histamine H2 receptor	0	20	0	20
Alpha-1D adrenergic receptor	0	33	1	35
5-hydroxytryptamine receptor 2A	0	43	4	49
5-hydroxytryptamine receptor 2C	0	45	4	49
Histamine H1 receptor	0	10	0	10
Histamine H1 receptor	0	36	3	41
D(3) dopamine receptor	0	34	3	44
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	6	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 2B	0	38	3	41
Alpha-1A adrenergic receptor	0	29	3	32
Histamine H2 receptor	20	5	0	31
D(1A) dopamine receptor	14	1	0	15
5-hydroxytryptamine receptor 6	0	35	1	38
5-hydroxytryptamine receptor 7	0	12	0	12
Voltage-dependent N-type calcium channel subunit alpha-1B	0	7	0	7
Sodium channel protein type 7 subunit alpha	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	10	0	10
Potassium voltage-gated channel subfamily H member 2	0	41	0	41
Voltage-dependent L-type calcium channel subunit alpha-1S	0	10	0	10
Voltage-dependent L-type calcium channel subunit alpha-1C	0	11	0	11
Sodium channel protein type 5 subunit alpha	0	9	0	9
Sodium channel protein type 9 subunit alpha	0	7	0	7
Sigma non-opioid intracellular receptor 1	0	6	1	7
Nuclear receptor subfamily 3 group C member 3	0	27	0	27
Canalicular multispecific organic anion transporter 1	0	33	0	33
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	35	1	36
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	5	0	5
Sodium channel protein type 8 subunit alpha	0	5	0	5
Histamine H3 receptor	0	7	0	7
Sodium channel protein type 10 subunit alpha	0	5	0	5
farnesoid X nuclear receptor	20	0	0	20
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	17	0	0	17
Chain A, Beta-lactamase	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, Ferritin light chain	5	0	0	5
endonuclease IV	8	0	0	8
hypoxia-inducible factor 1 alpha subunit	18	0	0	18
RAR-related orphan receptor gamma	34	0	0	34
Fumarate hydratase	19	0	0	19
GLI family zinc finger 3	41	0	0	41
Thrombopoietin	13	0	0	13
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
thyroid stimulating hormone receptor	21	0	0	21
nuclear receptor subfamily 1, group I, member 3	32	0	0	32
progesterone receptor	28	0	0	28
isocitrate dehydrogenase 1, partial	1	0	0	1
EWS/FLI fusion protein	21	0	0	21
retinoic acid nuclear receptor alpha variant 1	38	0	0	38
estrogen-related nuclear receptor alpha	39	0	0	39
polyprotein	19	0	0	19
67.9K protein	10	0	0	10
euchromatic histone-lysine N-methyltransferase 2	48	0	0	48
activating transcription factor 6	12	0	0	12
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	17	0	0	17
v-jun sarcoma virus 17 oncogene homolog (avian)	26	0	0	26
peripheral myelin protein 22 isoform 1	10	0	0	10
cellular tumor antigen p53 isoform a	14	0	0	14
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
vitamin D3 receptor isoform VDRA	16	0	0	16
thyroid hormone receptor beta isoform a	11	0	0	11
potassium voltage-gated channel subfamily H member 2 isoform d	26	0	0	26
heat shock protein beta-1	12	0	0	12
ubiquitin carboxyl-terminal hydrolase 2 isoform a	9	0	0	9
geminin	33	0	0	33
peripheral myelin protein 22	25	0	0	25
survival motor neuron protein isoform d	16	0	0	16
cytochrome P450 3A4 isoform 1	20	0	0	20
M-phase phosphoprotein 8	17	0	0	17
transient receptor potential cation channel subfamily V member 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	9	0	0	9
neuropeptide S receptor isoform A	11	0	0	11
Cellular tumor antigen p53	30	0	0	30
5-hydroxytryptamine receptor 1A	0	16	9	25
Cytochrome P450 2D6	0	16	1	18
D(4) dopamine receptor	0	21	1	27
5-hydroxytryptamine receptor 7	0	17	1	18
Sulfotransferase 1A1	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
Inositol monophosphatase 1	12	0	0	12
Sulfotransferase 2A1	0	2	0	2
TAR DNA-binding protein 43	7	0	0	7
Histamine H4 receptor	0	3	1	4
ATP-dependent phosphofructokinase	24	0	0	24
Solute carrier family 22 member 3	0	2	0	2
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	3	0	3
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Beta-2 adrenergic receptor	0	4	1	6
Sigma non-opioid intracellular receptor 1	0	10	1	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	15	0	0	15
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	20	0	0	20
Microtubule-associated protein tau	20	0	0	20
vitamin D (1,25- dihydroxyvitamin D3) receptor	27	0	0	27
Bloom syndrome protein isoform 1	14	0	0	14
cytochrome P450 2C19 precursor	13	0	0	13
cytochrome P450 2C9 precursor	9	0	0	9
muscleblind-like protein 1 isoform 1	4	0	0	4
Glutamate receptor 1	1	0	0	3
Glutamate receptor 2	17	0	0	19
Glutamate receptor 3	1	0	0	3
Glutamate receptor 4	1	0	0	3
Liver carboxylesterase 1	0	1	0	3
Glutamate receptor 3	0	0	1	1
Glutamate receptor 4	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	13	0	0	13
5-hydroxytryptamine receptor 3E	0	4	0	4
SMAD family member 2	8	0	0	8
PPM1D protein	5	0	0	5
SMAD family member 3	8	0	0	8
estrogen receptor 2 (ER beta)	27	0	0	27
retinoid X nuclear receptor alpha	28	0	0	28
G	16	0	0	16
peroxisome proliferator-activated receptor delta	21	0	0	21
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	8	0	0	8
thyroid stimulating hormone receptor	17	0	0	17
lysosomal alpha-glucosidase preproprotein	4	0	0	4
mu-type opioid receptor isoform MOR-1	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	12
transcriptional regulator ERG isoform 3	4	0	0	4
5-hydroxytryptamine receptor 2A	0	0	1	1
Solute carrier family 22 member 2	0	4	0	4
5-hydroxytryptamine receptor 3A	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	16	0	0	16
5-hydroxytryptamine receptor 3B	0	4	0	4
Interferon beta	23	0	0	23
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
ATP-dependent translocase ABCB1	0	19	0	26
Cytochrome P450 3A4	0	15	1	19
Neuronal acetylcholine receptor subunit alpha-4	2	2	0	4
Neuronal acetylcholine receptor subunit beta-2	2	2	0	4
Alpha-1B adrenergic receptor	0	26	3	29
D	0	18	0	18
Alpha-1D adrenergic receptor	0	22	3	25
D(4) dopamine receptor	0	15	0	15
Histamine H1 receptor	0	5	1	7
Alpha-1A adrenergic receptor	0	10	2	13
Alpha-1B adrenergic receptor	0	5	1	7
5-hydroxytryptamine receptor 3A	0	5	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Spike glycoprotein	25	2	6	33
D(2) dopamine receptor	0	27	2	30
5-hydroxytryptamine receptor 3D	0	4	0	4
Multidrug and toxin extrusion protein 2	0	4	0	4
5-hydroxytryptamine receptor 3C	0	4	0	4
Inositol hexakisphosphate kinase 1	16	0	0	16
Multidrug and toxin extrusion protein 1	0	4	0	4
cytochrome P450 2C9, partial	16	0	0	16
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	6	0	0	6
IDH1	17	0	0	17
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
lethal factor (plasmid)	15	0	0	15
Polyphenol oxidase 2	0	1	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	4	0	0	4
hypothetical protein, conserved	2	0	0	2
glucocerebrosidase	9	0	0	9
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
DNA polymerase iota isoform a (long)	12	0	0	12
DNA polymerase kappa isoform 1	8	0	0	8
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	6	0	6
Carbonic anhydrase 1	0	5	0	10
Carbonic anhydrase 2	0	5	0	10
Fatty acid-binding protein, liver	0	4	0	4
Integrin beta-3	8	1	0	9
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	8	1	0	9
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	4	0	7
Adenosine receptor A2a	0	1	0	4
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	5	0	0	5
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	4	0	0	4
short transient receptor potential channel 6 isoform 1	0	0	2	2
Muscarinic acetylcholine receptor M1	0	1	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	2	1	3
Genome polyprotein	0	1	1	2
dopamine D1 receptor	4	0	0	4
ATAD5 protein, partial	21	0	0	21
regulator of G-protein signaling 4	19	0	0	19
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
ATP-dependent translocase ABCB1	0	5	0	5
Beta-1 adrenergic receptor	0	5	1	6
Androgen receptor	0	6	0	6
D(3) dopamine receptor	0	17	0	17
Alpha-2B adrenergic receptor	0	16	3	19
ATP-dependent translocase ABCB1	0	5	0	5
Alpha-2C adrenergic receptor	0	16	3	19
Alpha-2A adrenergic receptor	0	16	3	19
D(1B) dopamine receptor	0	13	0	13
Alpha-synuclein	4	3	0	7
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	5	4	9
Potassium channel subfamily K member 9	0	1	0	1
mitogen-activated protein kinase 1	15	0	0	15
Vpr	2	0	0	2
Bile salt export pump	0	7	0	7
Major prion protein	0	0	4	4
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	14	0	15
UDP-glucuronosyltransferase 2B7	0	2	0	5
Cytochrome P450 2B6	0	1	1	2
Cytochrome P450 2J2	0	12	0	13
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
caspase 7, apoptosis-related cysteine protease	14	0	0	14
caspase-3	14	0	0	14
thyrotropin-releasing hormone receptor	2	0	0	2
Caspase-2	0	0	1	1
glp-1 receptor, partial	16	0	0	16
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	4
Translocator protein	0	2	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	7	2	9
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit beta type-11	0	0	0	1
phosphopantetheinyl transferase	12	0	0	12
Smad3	11	0	0	11
NADPH oxidase 1	0	5	0	5
Snq2p	0	0	0	9
Adenylate cyclase type 1	0	4	0	4
Histone H2A.x	12	0	0	12
Caspase-7	10	0	0	10
Spike glycoprotein	0	2	6	8
Replicase polyprotein 1ab	0	2	6	8
caspase-3	10	0	0	10
histone deacetylase 9 isoform 3	2	0	0	2
ras-related protein Rab-9A	13	0	0	13
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	2	6	8
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Albumin	0	1	4	6
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	5	1	7
Tyrosine-protein kinase Fyn	0	5	0	5
Procathepsin L	0	2	6	8
Replicase polyprotein 1a	0	2	6	8
Replicase polyprotein 1ab	0	2	6	8
Replicase polyprotein 1ab	0	2	6	8
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	2	5
Replicase polyprotein 1ab	0	3	6	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Sphingomyelin phosphodiesterase	0	2	0	2
D(2) dopamine receptor	0	5	0	5
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	4	0	4
Adenylate cyclase type 3	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	4	0	4
Adenylate cyclase type 4	0	4	0	4
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	10	0	10
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	6	0	6
Pleiotropic ABC efflux transporter of multiple drugs	0	9	0	18
Mu-type opioid receptor	0	14	3	18
Glutamate receptor ionotropic, NMDA 1	0	3	0	7
Adenylate cyclase type 8	0	4	0	4
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	10	2	13
Kappa-type opioid receptor	0	12	2	15
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit alpha type-6	0	0	3	4
Calmodulin	0	1	3	4
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	7
Glutamate receptor ionotropic, NMDA 2B	0	3	0	7
Glutamate receptor ionotropic, NMDA 2C	0	3	0	7
Adenylate cyclase type 6	0	4	0	4
Adenylate cyclase type 5	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	5
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	3	0	7
Adenylyl cyclase 7	0	4	0	4
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	7
D	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	2	6	8
Glutamate receptor ionotropic, NMDA 3A	0	3	0	7
NPC intracellular cholesterol transporter 1 precursor	9	0	0	9
Sodium-dependent noradrenaline transporter	0	4	0	4
Tryptophan 5-hydroxylase 1	0	3	0	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Acetylcholinesterase	0	3	0	3
Aromatase	0	1	0	1
Sigma intracellular receptor 2	0	8	0	8
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	4	0	4
Transporter	0	16	0	16
Trypanothione reductase	0	1	0	1
Envelope glycoprotein	0	0	4	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	6	1	7
Translocator protein	0	2	0	2
Translocator protein	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	1	7
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	6	1	7
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Luciferase	12	0	0	12
Beta-1 adrenergic receptor	0	2	1	4
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
Beta-2 adrenergic receptor	0	6	0	7
Beta-1 adrenergic receptor	0	5	1	7
Endothelin receptor type B	0	2	0	2
5-hydroxytryptamine receptor 3A	0	4	0	4
Endothelin receptor type B	0	2	0	2
Beta-3 adrenergic receptor	0	4	0	4
Cytochrome P450 2C19	0	6	0	8
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 5A	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	5	0	5
5-hydroxytryptamine receptor 1A	0	2	0	2
PAX8	0	0	0	1
pregnane X receptor	4	0	0	4
aryl hydrocarbon receptor	16	0	0	16
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
flap endonuclease 1	6	0	0	6
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Solute carrier family 22 member 3	0	2	0	2
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	5
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
15-lipoxygenase, partial	9	0	0	9
GALC protein	5	0	0	5
Sex hormone-binding globulin	0	0	1	1
Beta-glucuronidase	0	1	0	1
Corticosteroid-binding globulin	0	2	0	2
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
G-protein coupled bile acid receptor 1	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Gamma-aminobutyric acid	0	1	1	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Caspase-7	2	0	0	2
Histamine H3 receptor	0	0	0	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
huntingtin isoform 2	5	0	0	5
Cytochrome P450 2C8	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Cytochrome P450 1B1	0	2	0	2
Adenosine receptor A3	0	5	1	6
Beta-3 adrenergic receptor	0	4	1	5
alternatively spliced Trp4	0	0	1	1
XBP1	0	2	0	2
DNA damage-inducible transcript 3 protein	0	2	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
Glycine receptor subunit alpha-1	0	0	3	3
Nociceptin receptor	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	3	0	3
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
nonstructural protein 1	4	0	0	4
Cocaine esterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
UDP-glucuronosyltransferase 1A9	0	1	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	3	0	3
Delta-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	4	1	8
Kappa-type opioid receptor	0	3	1	5
Kappa-type opioid receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	0	3
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Solute carrier family 22 member 2	0	1	0	1
N-glycosylase/DNA lyase	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
apical membrane antigen 1, AMA1	7	0	0	7
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
Carbonic anhydrase 12	0	1	0	5
Tyrosine-protein kinase Lck	0	1	0	1
Carbonic anhydrase 3	0	1	0	5
Carbonic anhydrase 4	0	1	0	5
Carbonic anhydrase 6	0	1	0	5
Carbonic anhydrase 5A, mitochondrial	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase 7	0	1	0	5
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	1	0	5
Large neutral amino acids transporter small subunit 1	0	4	0	5
SLC16A10 protein	0	0	0	4
Carbonic anhydrase 9	0	1	0	6
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase-like protein, putative	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Monocarboxylate transporter 10	0	0	0	4
Carbonic anhydrase 15	0	2	0	6
Carbonic anhydrase 13	0	0	0	3
Carbonic anhydrase 14	0	0	0	4
Carbonic anhydrase 5B, mitochondrial	0	1	0	5
phosphoglycerate kinase	1	0	0	1
Beta-2 adrenergic receptor	0	3	1	4
Catechol O-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1E	0	1	0	1
D	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
galanin receptor type 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	4	0	4
Amine oxidase [flavin-containing] B	0	3	0	3
Synaptic vesicular amine transporter	0	2	0	2
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	2	2
Endothelin-1 receptor	0	2	1	3
Type-2 angiotensin II receptor	0	3	0	3
Angiotensin-converting enzyme	0	2	0	2
5-hydroxytryptamine receptor 3B	0	2	0	2
G-protein coupled receptor	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] A	0	7	0	8
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	6	0	7
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	2	0	3
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Chain A, Cruzipain	2	0	0	2
Sodium/iodide cotransporter	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
caspase recruitment domain family, member 15	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Guanine nucleotide-binding protein G	2	0	0	2
Beta lactamase (plasmid)	0	1	0	1
Quinolone resistance protein NorA	0	2	0	3
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
bcl-2-related protein A1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Aldehyde oxidase 1	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Aldehyde oxidase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	3	0	4
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Membrane primary amine oxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Carbonic anhydrase 13	0	0	0	1
Phospholipase A-2-activating protein	0	2	0	2
DNA polymerase III, partial	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	2	0	2
WD repeat-containing protein 48	0	2	0	2
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	2	1	8
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Mcl-1	0	1	0	1
neutrophil cytosol factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	1	3
Adenosine receptor A2a	0	1	1	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
chaperonin GroEL	1	0	0	1
Melatonin receptor type 1A	0	1	0	1
Melatonin receptor type 1B	0	1	0	1
hemoglobin subunit beta	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Parkin	1	0	0	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 2E1	0	1	0	1
Cytochrome P450 4B1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Cytochrome P450 2A7	0	1	0	1
Cytochrome P450 3A7	0	1	0	1
Cytochrome P450 2F1	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Cytochrome P450 4F8	0	1	0	1
Cytochrome P450 4A11	0	1	0	1
Cytochrome P450 4F3	0	1	0	1
Cytochrome P450 2A13	0	1	0	1
Cytochrome P450 4A22	0	1	0	1
Vitamin D 25-hydroxylase	0	1	0	1
Cytochrome P450 2U1	0	1	0	1
Cytochrome P450 2W1	0	1	0	1
Cytochrome P450 2S1	0	1	0	1
Cytochrome P450 3A43	0	1	0	1
REST corepressor 3	0	1	0	1
Genome polyprotein	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Protein kinase C alpha type	0	1	0	1
Beta-glucuronidase	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Protein kinase C eta type	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Protein kinase C theta type	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Stromelysin-1	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (252)

Protein Targets (914)

Hypochondriacal Neuroses

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (252)

Drugs Studied (140)

Protein Targets (914)