Page last updated: 2024-09-28

Blepharospasm-Oromandibular Dyskinesia

A syndrome characterized by orofacial DYSTONIA; including BLEPHAROSPASM; forceful jaw opening; lip retraction; platysma muscle spasm; and tongue protrusion. It primarily affects older adults, with an incidence peak in the seventh decade of life. (From Adams et al., Principles of Neurology, 6th ed, p108)

Synonyms(9)

Synonym
Blepharospasm-Oromandibular Dystonia
Blepharospasm-Oromandibular Dystonia Syndrome
Syndrome, Blepharospasm-Oromandibular Dystonia
Idiopathic Orofacial Dyskinesia
Blepharospasm-Oromandibular Dystonia Syndrome, Idiopathic
Blepharospasm-Oromandibular Dyskinesia
Idiopathic Blepharospasm-Oromandibular Dystonia Syndrome
Brueghel Syndrome
Meige Syndrome

Research Excerpts

Overview

ExcerptReference
"Meige syndrome is a relatively rare type of oral facial dystonia."( Atake, K; Hori, H; Katsuki, A; Yoshimura, R, 2016)

Treatment

ExcerptReference
"We report a case of Meige syndrome with apraxia of lid opening that lasted for about seven months after discontinuation of sulpiride treatment."( Horiguchi, J; Kagaya, A; Kikkawa, S; Morinobu, S; Tsuji, S; Yamashita, H; Yamawaki, S, 2002)

Research

Studies (79)

TimeframeStudies, This Condition (%)All Conditions %
pre-199027 (34.18)23.3326
1990's15 (18.99)12.5806
2000's21 (26.58)18.1394
2010's12 (15.19)28.8240
2020's4 (5.06)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0medium31
choline0low10
homovanillic acid0low20
amitriptyline0low20
baclofen0low30
biperiden0low10
bromhexine0low10
clonazepam0medium91
clonidine0medium11
valproic acid0medium21
domperidone0low10
gentamicin0low10
guanfacine0low10
haloperidol0medium41
lidocaine0medium21
methylphenidate0low20
orphenadrine0low10
perazine0low10
piracetam0low20
pirenzepine0low10
risperidone0medium41
sulpiride0low30
thioridazine0low10
tizanidine0medium11
trifluoperazine0low20
trihexyphenidyl0low70
vigabatrin0low10
zolpidem0low10
apomorphine0medium21
tetrabenazine0low20
kanamycin a0low10
carbostyril0low10
levodopa0low80
deanol0low20
thiazoles0low10
methoxyhydroxyphenylglycol0low10
lithium carbonate0low10
pimozide0low10
selegiline0low10
lisuride0medium42
bromocriptine0low10
glutamic acid0low10
methyldopa0low10
pergolide0low10
fomesafen0low20
aripiprazole0low20
fluorodeoxyglucose f180low10
perospirone0low10
inositol 3-phosphate0low10
cannabidiol0low10
methimazole0low10
nadp0low10
ranitidine0low10
lithium0low10
levetiracetam0low30
fluvoxamine0low10
ergoline0medium41
tiapamil hydrochloride0low30
paliperidone palmitate0low20
jaw0low20
ceruletide0low10
quetiapine fumarate0low10
brass0low10
clozapine0low30
olanzapine0low30
allopurinol0low10
eye0low10
carbidopa0low10

Protein Targets (794)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
interleukin 82002
TDP1 protein240024
AR protein240024
thyroid stimulating hormone receptor110011
estrogen receptor 2 (ER beta)110011
progesterone receptor140014
glucocorticoid receptor [Homo sapiens]170017
estrogen-related nuclear receptor alpha170017
estrogen nuclear receptor alpha230023
IDH16006
euchromatic histone-lysine N-methyltransferase 2320032
Bloom syndrome protein isoform 1120012
transcriptional regulator ERG isoform 34004
thyroid hormone receptor beta isoform 2140014
ras-related protein Rab-9A5005
nuclear factor erythroid 2-related factor 2 isoform 1160016
geminin180018
survival motor neuron protein isoform d8008
lamin isoform A-delta10200020
ATP-binding cassette sub-family C member 3021021
Multidrug resistance-associated protein 4021021
Polyphenol oxidase 20305
Voltage-dependent calcium channel gamma-2 subunit110011
Bile salt export pump031031
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p53130013
Glutamate receptor 2112114
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0112
Xanthine dehydrogenase/oxidase0202
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 435005
Canalicular multispecific organic anion transporter 1021021
Shiga toxin subunit A0101
Histamine H3 receptor0101
Chain A, HADH2 protein110011
Chain B, HADH2 protein110011
thioredoxin reductase210021
USP1 protein, partial8008
NFKB1 protein, partial100010
GLS protein200020
cytochrome P450 family 3 subfamily A polypeptide 4120012
cytochrome P450 2D6150015
arylsulfatase A180018
cytochrome P450 2D6 isoform 1130013
D(1A) dopamine receptor180018
chromobox protein homolog 1200020
atrial natriuretic peptide receptor 2 precursor7007
serine/threonine-protein kinase mTOR isoform 1100010
muscarinic acetylcholine receptor M1170017
Solute carrier family 22 member 1 0608
Polyunsaturated fatty acid lipoxygenase ALOX15B9009
Voltage-dependent L-type calcium channel subunit alpha-1F0808
5-hydroxytryptamine receptor 4026026
Albumin0066
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B1013013
Muscarinic acetylcholine receptor M2016118
Muscarinic acetylcholine receptor M4017119
Muscarinic acetylcholine receptor M10808
Muscarinic acetylcholine receptor M30808
Muscarinic acetylcholine receptor M40808
5-hydroxytryptamine receptor 2C013114
Muscarinic acetylcholine receptor M50808
Muscarinic acetylcholine receptor M5017018
Alpha-2A adrenergic receptor030232
Muscarinic acetylcholine receptor M20808
Muscarinic acetylcholine receptor M1017322
Angiotensin-converting enzyme012012
D(2) dopamine receptor027944
5-hydroxytryptamine receptor 2A015217
Alpha-2B adrenergic receptor029130
Alpha-2C adrenergic receptor026228
5-hydroxytryptamine receptor 1A022022
Muscarinic acetylcholine receptor M3019121
D(1A) dopamine receptor022228
D(1B) dopamine receptor07010
UDP-glucuronosyltransferase 1A40004
Sodium-dependent noradrenaline transporter 015015
Histamine H2 receptor014014
Alpha-1D adrenergic receptor023124
5-hydroxytryptamine receptor 2A027332
5-hydroxytryptamine receptor 2C029433
5-hydroxytryptamine receptor 1B018018
5-hydroxytryptamine receptor 1D0606
5-hydroxytryptamine receptor 1F0606
5-hydroxytryptamine receptor 2B012214
5-hydroxytryptamine receptor 60303
Histamine H1 receptor0606
Sodium-dependent serotonin transporter023023
5-hydroxytryptamine receptor 7 0909
5-hydroxytryptamine receptor 5A0303
5-hydroxytryptamine receptor 5B0303
Histamine H1 receptor020325
D(3) dopamine receptor025436
Sodium channel protein type 1 subunit alpha0404
Sodium channel protein type 4 subunit alpha0505
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0505
5-hydroxytryptamine receptor 2B025126
Alpha-1A adrenergic receptor015217
Histamine H2 receptor111014
D(1A) dopamine receptor4105
5-hydroxytryptamine receptor 6020021
5-hydroxytryptamine receptor 70505
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0808
Sodium-dependent dopamine transporter 0808
Potassium voltage-gated channel subfamily H member 2024024
Voltage-dependent L-type calcium channel subunit alpha-1S0808
Voltage-dependent L-type calcium channel subunit alpha-1C0809
Sodium channel protein type 5 subunit alpha0808
Sodium channel protein type 9 subunit alpha0505
Sigma non-opioid intracellular receptor 10314
5-hydroxytryptamine receptor 4 0303
Nuclear receptor subfamily 3 group C member 3 011011
Sodium channel protein type 2 subunit alpha0404
Ataxin-2170017
Sigma non-opioid intracellular receptor 1015015
5-hydroxytryptamine receptor 3B0505
Sodium channel protein type 3 subunit alpha0505
Sodium channel protein type 11 subunit alpha0404
Sodium channel protein type 8 subunit alpha0404
Histamine H3 receptor0606
Sodium channel protein type 10 subunit alpha0404
Chain A, TYROSYL-DNA PHOSPHODIESTERASE110011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, 2-oxoglutarate Oxygenase7007
Luciferase100010
acetylcholinesterase110011
phosphopantetheinyl transferase120012
hypoxia-inducible factor 1 alpha subunit8008
RAR-related orphan receptor gamma150015
GLI family zinc finger 3160016
Microtubule-associated protein tau110011
aldehyde dehydrogenase 1 family, member A1100010
nuclear receptor subfamily 1, group I, member 3160016
regulator of G-protein signaling 4200020
retinoic acid nuclear receptor alpha variant 1160016
farnesoid X nuclear receptor100010
peroxisome proliferator-activated receptor delta9009
peroxisome proliferator activated receptor gamma110011
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
thyroid stimulating hormone receptor100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)110011
Histone H2A.x7007
cellular tumor antigen p53 isoform a4004
cytochrome P450 2C19 precursor9009
cytochrome P450 2C9 precursor6006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
vitamin D3 receptor isoform VDRA100010
potassium voltage-gated channel subfamily H member 2 isoform d130013
mitogen-activated protein kinase 19009
nuclear receptor ROR-gamma isoform 1110011
peripheral myelin protein 22170017
cytochrome P450 3A4 isoform 1140014
lethal factor (plasmid)7007
Gamma-aminobutyric acid receptor subunit pi147021
Integrin beta-34015
Integrin alpha-IIb4015
5-hydroxytryptamine receptor 1A013619
Tryptophan 5-hydroxylase 10303
Gamma-aminobutyric acid receptor subunit beta-1147021
Alpha-1B adrenergic receptor013114
Gamma-aminobutyric acid receptor subunit delta147021
Gamma-aminobutyric acid receptor subunit gamma-2147223
D016017
D(3) dopamine receptor014014
Alpha-2B adrenergic receptor011112
Gamma-aminobutyric acid receptor subunit alpha-5147021
Gamma-aminobutyric acid receptor subunit alpha-3147021
D(2) dopamine receptor0707
D(4) dopamine receptor013321
Alpha-2C adrenergic receptor011112
Alpha-2A adrenergic receptor011112
Gamma-aminobutyric acid receptor subunit gamma-1147021
Gamma-aminobutyric acid receptor subunit alpha-2147021
Alpha-1D adrenergic receptor011112
D(1B) dopamine receptor012012
Gamma-aminobutyric acid receptor subunit alpha-4147021
Gamma-aminobutyric acid receptor subunit gamma-3147021
Gamma-aminobutyric acid receptor subunit alpha-6147021
D(4) dopamine receptor014115
Spike glycoprotein170017
D(2) dopamine receptor024631
Gamma-aminobutyric acid receptor subunit alpha-1147223
Gamma-aminobutyric acid receptor subunit beta-3147021
Gamma-aminobutyric acid receptor subunit beta-2147223
E3 ubiquitin-protein ligase Mdm20101
D0101
GABA theta subunit147021
D0606
ATPase family AAA domain-containing protein 5110011
Gamma-aminobutyric acid receptor subunit epsilon147021
ATP-dependent phosphofructokinase210021
Chain A, JmjC domain-containing histone demethylation protein 3A100010
5-hydroxytryptamine receptor 3E0303
SMAD family member 23003
Fumarate hydratase9009
PPM1D protein4004
SMAD family member 33003
EWS/FLI fusion protein110011
retinoid X nuclear receptor alpha9009
pregnane X nuclear receptor130013
G6006
polyprotein9009
67.9K protein5005
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)5005
lysosomal alpha-glucosidase preproprotein4004
mu-type opioid receptor isoform MOR-10022
nuclear factor erythroid 2-related factor 2 isoform 22002
heat shock protein beta-16006
histone acetyltransferase KAT2A isoform 1100010
5-hydroxytryptamine receptor 2A0022
neuropeptide S receptor isoform A3003
Solute carrier family 22 member 20506
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 3B0303
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 6006
ATP-dependent translocase ABCB108012
Cytochrome P450 3A4011013
Neuronal acetylcholine receptor subunit alpha-41203
Neuronal acetylcholine receptor subunit beta-21203
Histamine H1 receptor0404
5-hydroxytryptamine receptor 70808
Alpha-1A adrenergic receptor09110
Alpha-1B adrenergic receptor0617
5-hydroxytryptamine receptor 3A0404
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0404
Inositol monophosphatase 1100010
5-hydroxytryptamine receptor 3D0303
Multidrug and toxin extrusion protein 20505
5-hydroxytryptamine receptor 3C0303
Inositol hexakisphosphate kinase 16006
Multidrug and toxin extrusion protein 10707
cytochrome P450 2C9, partial6006
ATAD5 protein, partial170017
activating transcription factor 64004
Gamma-aminobutyric acid type B receptor subunit 20325
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10325
Gamma-aminobutyric acid type B receptor subunit 10202
flap endonuclease 16006
Cytochrome P450 2D6010011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
Genome polyprotein 0112
dopamine D1 receptor4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
ATP-dependent translocase ABCB10202
Beta-1 adrenergic receptor0404
Androgen receptor0202
ATP-dependent translocase ABCB10202
Alpha-synuclein0303
Acetylcholinesterase0202
L-lactate dehydrogenase A chain0101
Cytochrome P450 1A10202
Cytochrome P450 1A20404
Cytochrome P450 2C11 0202
Cytochrome P450 2A60202
Cytochrome P450 2C9 0607
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Fatty acid-binding protein, liver0101
Cannabinoid receptor 10101
Cytochrome P450 2B60101
Cytochrome P450 3A50101
Cannabinoid receptor 10102
Cytochrome P450 3A70101
Caspase-10011
Cytochrome P450 2C190203
Cannabinoid receptor 2 0113
Mu-type opioid receptor0617
Peroxisome proliferator-activated receptor gamma0011
Delta-type opioid receptor0202
Kappa-type opioid receptor0606
Cholinesterase0101
N-acylethanolamine-hydrolyzing acid amidase0101
Cytochrome P450 1B10202
Heat sensitive channel TRPV30112
Sigma intracellular receptor 20202
Transient receptor potential cation channel subfamily A member 10112
Transient receptor potential cation channel subfamily V member 10112
Transient receptor potential cation channel subfamily M member 80101
Transient receptor potential cation channel subfamily V member 40213
Transient receptor potential cation channel subfamily V member 20213
G-protein coupled receptor 550011
Diacylglycerol lipase-alpha0101
Chain A, serum paraoxonase0101
DNA polymerase kappa isoform 15005
Carbonic anhydrase 120203
Carbonic anhydrase 10407
Carbonic anhydrase 20407
Carbonic anhydrase 30203
Neutrophil cytosol factor 10101
Carbonic anhydrase 40102
Carbonic anhydrase 60203
Carbonic anhydrase 5A, mitochondrial0203
Carbonic anhydrase 70203
Carbonic anhydrase 90204
Carbonic anhydrase 130101
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0203
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0303
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0102
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70202
Solute carrier family 22 member 10203
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-10426
Gamma-aminobutyric acid receptor subunit beta-10415
Gamma-aminobutyric acid receptor subunit gamma-20426
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30415
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50426
Gamma-aminobutyric acid receptor subunit alpha-30426
Gamma-aminobutyric acid receptor subunit alpha-20426
Gamma-aminobutyric acid receptor subunit beta-20426
Gamma-aminobutyric acid receptor subunit alpha-40415
Gamma-aminobutyric acid receptor subunit epsilon0303
Gamma-aminobutyric acid receptor subunit alpha-60415
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit gamma-30303
Gamma-aminobutyric acid receptor subunit theta0303
Chain A, Ferritin light chain5005
Chain A, Cruzipain1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
Beta-1 adrenergic receptor 0112
Alpha-1B adrenergic receptor 0022
Membrane primary amine oxidase 0101
Solute carrier family 22 member 30202
Alpha-1A adrenergic receptor0022
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0314
Adenosine receptor A2b0011
Adenosine receptor A2a0113
Alpha-2B adrenergic receptor0001
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Nischarin0303
caspase 7, apoptosis-related cysteine protease6006
glucocerebrosidase3003
bromodomain adjacent to zinc finger domain 2B5005
caspase-36006
Adenylate cyclase type 1 0202
peripheral myelin protein 22 isoform 18008
DNA polymerase beta3003
DNA polymerase iota isoform a (long)100010
short transient receptor potential channel 6 isoform 10011
M-phase phosphoprotein 8110011
transient receptor potential cation channel subfamily V member 12002
Bile salt export pump0606
Calmodulin-10112
Beta-2 adrenergic receptor0404
Beta-1 adrenergic receptor0303
Endothelin receptor type B0101
Adenylate cyclase type 30202
Sodium-dependent dopamine transporter0718
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
Adenosine receptor A10405
Beta-3 adrenergic receptor0202
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 2C 0303
5-hydroxytryptamine receptor 2A0303
Adenylate cyclase type 80202
5-hydroxytryptamine receptor 5A0101
Cytochrome P450 2J20405
D(2) dopamine receptor0202
D(3) dopamine receptor0202
Gastrin/cholecystokinin type B receptor0202
D(2) dopamine receptor0202
Calmodulin 0022
5-hydroxytryptamine receptor 2B0303
Adenylate cyclase type 60202
Adenylate cyclase type 50202
5-hydroxytryptamine receptor 40202
Transporter0404
Cholecystokinin receptor type A0202
5-hydroxytryptamine receptor 1A0202
Adenylyl cyclase 7 0202
Histamine H4 receptor0314
Sigma non-opioid intracellular receptor 10505
Transporter0404
glp-1 receptor, partial7007
GALC protein4004
Smad36006
alpha-galactosidase1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a6006
Retinoic acid receptor RXR-alpha0011
Disintegrin and metalloproteinase domain-containing protein 174004
Cytochrome P450 1A2 0202
Sigma intracellular receptor 20303
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0023
thyroid hormone receptor beta isoform a4004
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Histone deacetylase 30303
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40303
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0102
4-aminobutyrate aminotransferase, mitochondrial0102
Histone deacetylase 10303
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80303
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60303
Histone deacetylase 90303
Histone deacetylase 50303
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0202
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0202
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10213
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0315
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, NMDA 2A 0315
Glutamate receptor ionotropic, NMDA 2B0315
Glutamate receptor ionotropic, NMDA 2C0315
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0202
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0315
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0315
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0315
POU domain, class 2, transcription factor 10001
15-lipoxygenase, partial5005
Thrombopoietin4004
nonstructural protein 13003
Cocaine esterase0202
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0303
UDP-glucuronosyltransferase 1A90103
Potassium channel subfamily K member 20325
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70204
C-8 sterol isomerase0202
Delta-type opioid receptor0202
Mu-type opioid receptor0303
Kappa-type opioid receptor0101
Kappa-type opioid receptor0101
5-hydroxytryptamine receptor 2A0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Protease 0202
ClpP2002
Solute carrier family 22 member 80001
Chymotrypsinogen A0101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
chaperonin-containing TCP-1 beta subunit homolog1001
Synaptic vesicle glycoprotein 2A0202
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA14004
pyruvate kinase2002
hexokinase-4 isoform 11001
atrial natriuretic peptide receptor 1 precursor3003
glucokinase regulatory protein1001
importin subunit beta-1 isoform 13003
snurportin-13003
DNA polymerase eta isoform 12002
Epidermal growth factor receptor0303
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0303
Polyunsaturated fatty acid lipoxygenase ALOX150404
Tyrosinase0101
Carbonic anhydrase0001
Solute carrier family 15 member 10202
Carbonic anhydrase0102
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 0102
Carbonic anhydrase0001
Carbonic anhydrase0102
Carbonic anhydrase 0102
Monocarboxylate transporter 100001
Carbonic anhydrase 150102
Carbonic anhydrase 130001
phosphoglycerate kinase2002
Chain A, Beta-lactamase6006
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Beta-2 adrenergic receptor0202
Myeloperoxidase0101
Cholinesterase0202
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Acetylcholinesterase 0101
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear receptor ROR-gamma3003
Nuclear factor erythroid 2-related factor 20001
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Dopamine beta-hydroxylase 0202
Lactoperoxidase0101
Lanosterol 14-alpha demethylase0101
endonuclease IV3003
Caspase 6, apoptosis-related cysteine peptidase0001
thioredoxin glutathione reductase1001
hypothetical protein, conserved2002
estrogen receptor beta isoform 10101
muscleblind-like protein 1 isoform 12002
Rap guanine nucleotide exchange factor 31001
Cystathionine gamma-lyase0101
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
pregnane X receptor4004
Parkin2002
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
perilipin-50101
perilipin-10101
serine/threonine-protein kinase PLK11001
eyes absent homolog 2 isoform a1001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Adenosine receptor A30202
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Thromboxane-A synthase 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Leukotriene B4 receptor 10001
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Beta-2 adrenergic receptor0001
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Broad substrate specificity ATP-binding cassette transporter ABCG20202
FAD-linked sulfhydryl oxidase ALR0001
Glucose-6-phosphate 1-dehydrogenase0101
DNA polymerase III, partial1001
XBP10101
Caspase-72002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
caspase-32002
huntingtin isoform 22002
nuclear factor NF-kappa-B p105 subunit isoform 11001
DNA damage-inducible transcript 3 protein0101
Voltage-dependent T-type calcium channel subunit alpha-1G0011
Ubiquitin carboxyl-terminal hydrolase 10202
Glycine receptor subunit alpha-10022
WD repeat-containing protein 480202
Guanine nucleotide-binding protein G3003
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor DM10101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor0101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M20101
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Cytochrome P450 2B10101
Amine oxidase [flavin-containing] B0203
Amine oxidase [flavin-containing] A 0203
Amine oxidase [flavin-containing] A 0202
Type-1 angiotensin II receptor0101
C-X-C chemokine receptor type 30101
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A0001
Amine oxidase [flavin-containing] B0001
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 40101
D(2) dopamine receptor0101
Synaptic vesicular amine transporter0213
Synaptic vesicular amine transporter0101
Synaptic vesicular amine transporter0101
Snq2p0002
NPC intracellular cholesterol transporter 1 precursor2002
Albumin0112
Replicase polyprotein 1ab0101
Pleiotropic ABC efflux transporter of multiple drugs0204
Proteasome subunit alpha type-60011
Cathepsin D 0101
Aldehyde oxidase0002
Mucosa-associated lymphoid tissue lymphoma translocation protein 10101
Genome polyprotein 0101
NADPH oxidase 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
DNA repair protein RAD52 homolog isoform a0001
Lysozyme C-10101
Glycoprotein hormones alpha chain1001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Protein kinase C alpha type0101
Beta-glucuronidase0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Trypanothione reductase0202
Protein kinase C gamma type0101
Protein kinase C beta type0101
DNA-dependent protein kinase catalytic subunit0101
Protein kinase C eta type0101
Calcium-dependent protein kinase 40101
Emopamil-binding protein-like0101
Protein kinase C theta type0101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Translocator protein0101
Sphingosine-1-phosphate lyase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]