Roles > androstane receptor agonist
Page last updated: 2024-08-05 15:31:08

androstane receptor agonist

An agonist that selectively binds to and activates androstane receptors.

ChEBI ID: 77326

Members (1)

MemberDefinitionClass
diethylhexyl phthalateA phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.bis(2-ethylhexyl) phthalate

Research

Studies (3,272)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990496 (15.16)18.7374
1990's294 (8.99)18.2507
2000's606 (18.52)29.6817
2010's1,100 (33.62)24.3611
2020's776 (23.72)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials28 (0.81%)5.53%
Reviews172 (5.01%)6.00%
Case Studies7 (0.20%)4.05%
Observational1 (0.03%)0.25%
Other3,228 (93.95%)84.16%

Protein Targets (56)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency22.387211
AR proteinHomo sapiens (human)Potency29.519367
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency50.118711
Cellular tumor antigen p53Homo sapiens (human)Potency13.685411
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency50.118711
chromobox protein homolog 1Homo sapiens (human)Potency89.125111
cytochrome P450 2C9, partialHomo sapiens (human)Potency17.829311
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency15.848922
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency6.326111
estrogen nuclear receptor alphaHomo sapiens (human)Potency31.482133
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency27.306022
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency17.687622
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency31.622811
farnesoid X nuclear receptorHomo sapiens (human)Potency15.593922
GVesicular stomatitis virusPotency17.829311
GABA theta subunitRattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency15.848911
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency15.848911
GLI family zinc finger 3Homo sapiens (human)Potency54.482712
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency6.164511
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency17.829311
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency17.829312
Interferon betaHomo sapiens (human)Potency17.829311
interleukin 8Homo sapiens (human)Potency84.126711
lethal factor (plasmid)Bacillus anthracis str. A2012Potency7.943311
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency68.589622
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency3.890011
Nuclear receptor ROR-gammaHomo sapiens (human)Potency74.978011
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency14.731833
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency34.665411
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency54.941011
pregnane X nuclear receptorHomo sapiens (human)Potency10.492222
pregnane X receptorRattus norvegicus (Norway rat)Potency11.220211
progesterone receptorHomo sapiens (human)Potency60.117922
RAR-related orphan receptor gammaMus musculus (house mouse)Potency0.863511
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency7.695911
retinoid X nuclear receptor alphaHomo sapiens (human)Potency2.753611
SMAD family member 2Homo sapiens (human)Potency21.875111
SMAD family member 3Homo sapiens (human)Potency21.875111
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency24.336511
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.223911
thyroid stimulating hormone receptorHomo sapiens (human)Potency3.857111
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency7.763333
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