trifluoperazine has been researched along with Carcinoma, Hepatocellular in 10 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preincubation of hepatoma cells and human skin fibroblasts in the presence of the calmodulin antagonists trifluoperazine and N-(6-aminohexyl)-5-chloro-1-naphthalene sulfonamide resulted in a dose-dependent suppression of [14C]mevalonolactone incorporation into cholesterol." | 1.27 | Calmodulin antagonists suppress cholesterol synthesis by inhibiting sterol delta 24 reductase. ( Buddecke, E; Filipovic, I, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, J | 1 |
| Huang, Z | 1 |
| Chen, X | 1 |
| Luo, R | 1 |
| Cai, H | 1 |
| Wang, H | 1 |
| Zhang, H | 1 |
| Sun, T | 1 |
| Zhang, Y | 1 |
| Chen, MH | 1 |
| Yang, WL | 1 |
| Lin, KT | 1 |
| Liu, CH | 1 |
| Liu, YW | 1 |
| Huang, KW | 1 |
| Chang, PM | 1 |
| Lai, JM | 1 |
| Hsu, CN | 1 |
| Chao, KM | 1 |
| Kao, CY | 1 |
| Huang, CY | 1 |
| Maier, O | 1 |
| Hoekstra, D | 1 |
| Boynton, AL | 1 |
| MacManus, JP | 1 |
| Whitfield, JF | 1 |
| Park, JG | 1 |
| Lee, SK | 1 |
| Hong, IG | 1 |
| Kim, HS | 1 |
| Lim, KH | 1 |
| Choe, KJ | 1 |
| Kim, WH | 1 |
| Kim, YI | 1 |
| Tsuruo, T | 1 |
| Gottesman, MM | 1 |
| Murata, T | 1 |
| Yamaguchi, M | 2 |
| Said, HM | 1 |
| Ortiz, A | 1 |
| Ma, TY | 1 |
| McCloud, E | 1 |
| Shen, HM | 1 |
| Yang, CF | 1 |
| Ding, WX | 1 |
| Liu, J | 1 |
| Ong, CN | 1 |
| Inagaki, S | 1 |
| Filipovic, I | 1 |
| Buddecke, E | 1 |
10 other studies available for trifluoperazine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Trifluoperazine Activates FOXO1-Related Signals to Inhibit Tumor Growth in Hepatocellular Carcinoma.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Forkhead Box Protein | 2017 |
Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Chlorpromazine; Data Collection; Databases, | 2011 |
Trans-Golgi network and subapical compartment of HepG2 cells display different properties in sorting and exiting of sphingolipids.
Topics: 4-Chloro-7-nitrobenzofurazan; Biological Transport; Carcinoma, Hepatocellular; Cell Fractionation; C | 2003 |
Stimulation of liver cell DNA synthesis by oncomodulin, an MW 11 500 calcium-binding protein from hepatoma.
Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Carcinoma, Hepatocellular; Cells, Cultured; | 1982 |
MDR1 gene expression: its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Carrier Proteins | 1994 |
Ca2+ administration stimulates the binding of AP-1 factor to the 5'-flanking region of the rat gene for the Ca2+-binding protein regucalcin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation.
Topics: Antiemetics; Biological Transport; Bucladesine; Calcium; Calmodulin; Carcinogens; Carcinoma, Hepatoc | 1998 |
Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Caspases; Cycli | 2001 |
Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonuleic acid synthesis with proliferation of cloned rat hepatoma cells (H4-II-E).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
Calmodulin antagonists suppress cholesterol synthesis by inhibiting sterol delta 24 reductase.
Topics: Calmodulin; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cholesterol; Fibroblasts; Humans; | 1987 |