trifluoperazine has been researched along with Melanoma in 5 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, brain metastases remain the biggest threat to the survival and quality of life of melanoma patients." | 5.62 | Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux. ( Lin, W; Xi, H; Xia, Y; Xie, Y; Xiong, M; Xu, F; Xue, Q; Yang, H; Ye, T; Yu, L, 2021) |
| "However, brain metastases remain the biggest threat to the survival and quality of life of melanoma patients." | 1.62 | Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux. ( Lin, W; Xi, H; Xia, Y; Xie, Y; Xiong, M; Xu, F; Xue, Q; Yang, H; Ye, T; Yu, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, Y | 1 |
| Xu, F | 1 |
| Xiong, M | 1 |
| Yang, H | 1 |
| Lin, W | 1 |
| Xie, Y | 1 |
| Xi, H | 1 |
| Xue, Q | 1 |
| Ye, T | 1 |
| Yu, L | 1 |
| Jensen, H | 1 |
| Hagemann-Jensen, M | 1 |
| Lauridsen, F | 1 |
| Skov, S | 1 |
| Ramachandran, C | 1 |
| Yuan, ZK | 1 |
| Huang, XL | 1 |
| Krishan, A | 1 |
| Kitagawa, T | 1 |
| Amano, F | 1 |
| Akamatsu, Y | 1 |
| Supino, R | 1 |
| Prosperi, E | 1 |
| Formelli, F | 1 |
| Mariani, M | 1 |
| Parmiani, G | 1 |
5 other studies available for trifluoperazine and Melanoma
| Article | Year |
|---|---|
Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux.
Topics: Animals; Antineoplastic Agents; Antipsychotic Agents; Autophagy; Bone Neoplasms; Brain Neoplasms; Ce | 2021 |
Regulation of NKG2D-ligand cell surface expression by intracellular calcium after HDAC-inhibitor treatment.
Topics: Base Sequence; Calcium Signaling; Calmodulin; Calpain; Cell Line, Tumor; Cell Membrane; Depsipeptide | 2013 |
Doxorubicin resistance in human melanoma cells: MDR-1 and glutathione S-transferase pi gene expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Death; Cell Division; Cell Li | 1993 |
External ATP-induced passive permeability change and cell lysis of cultured transformed cells: action in serum-containing growth media.
Topics: Adenosine Triphosphate; Animals; Blood; Calcium; Calmodulin; Cell Membrane Permeability; Cell Surviv | 1988 |
Characterization of a doxorubicin-resistant murine melanoma line: studies on cross-resistance and its circumvention.
Topics: Animals; Cell Line; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Doxorubicin; Drug | 1986 |