Page last updated: 2024-11-05

trifluoperazine and Pregnancy

trifluoperazine has been researched along with Pregnancy in 62 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Trifluoperazine was administered to pregnant mice and rats by gastric intubation during the period of organogenesis."1.27Teratogenic effect of trifluoperazine in rats and mice. ( Friman Pérez, M; Rodríguez González, MD, 1985)
" Kinetic analysis of dose-response experiments revealed a noncompetitive fashion of inhibition by W-7 and a mixed fashion by TFP."1.26Inhibition by calmodulin antagonists of glioblast DNA synthesis and morphological changes induced by glia maturation factor. ( Ito, J; Kato, T; Okumura, K; Tanaka, R, 1982)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199051 (82.26)18.7374
1990's8 (12.90)18.2507
2000's3 (4.84)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhong, L1
Yan, CH1
Lu, CQ1
Xu, J1
Huang, H1
Shen, XM1
Kesim, M1
Yaris, F1
Kadioglu, M1
Yaris, E1
Kalyoncu, NI1
Ulku, C1
PRUETER, GW1
MCQUEEN, EG1
PSYCHOYOS, A1
VIVELL, O1
WEICKER, H1
HENRY, JB2
LITTLE, WA2
CHRISTIAN, CD2
Terry, PM1
Zeitner, RM1
Frank, MV1
Freeman, SM1
Goode, DJ1
Meltzer, HY1
Fang, VS1
Pizarro, M1
Puente, J1
Sapag-Hagar, M1
Ollivier-Bousquet, M1
Hochberg, Z2
Bick, T2
Perlman, R2
Lahav, M1
Barzilai, D1
Brooks, CL2
Landt, M2
Okumura, K1
Kato, T1
Ito, J1
Tanaka, R1
Giannattasio, G1
De Ferrari, ME1
Spada, A1
Bond, GR1
Van Zee, A1
Padma, S1
Subramanyam, C1
Tolón, R1
Franco, FS1
Villuendas, G1
Vicente, AB1
Palacios, N1
Cacicedo, L1
Beumont, P1
Bruwer, J1
Pimstone, B1
Vinik, A1
Utian, W1
Singh, M1
Tandon, R1
Slavney, PR1
Grau, JG1
Wolstenholme, WW1
Gautieri, RF1
Zwierzchowski, L1
Członkowska, M1
Siadkowska, E1
Guszkiewicz, A1
Jackson, CJ1
Jenkins, K1
Schrieber, L1
Schmidt, MH1
Lee, T1
van Harten, PN1
Kemperman, CJ1
Kihira, M1
Matsuzawa, K1
Tokuno, H1
Tomita, T1
Murray, D1
Harwood, P1
Eapen, E1
Shemesh, M1
Strauss, JF1
Hansel, W1
Shore, LS1
Izhar, M1
Poli, E1
Rusagara, JN1
Coruzzi, G1
Bertaccini, G1
Ullmann, MB1
Reimers, TJ1
Savineau, JP1
Mironneau, J1
Mironneau, C1
Fisher, GJ1
Kelley, LK1
Smith, CH1
Rodríguez González, MD1
Friman Pérez, M1
Kasugai, M1
Kato, H1
Iriyama, H1
Kato, M1
Ninagawa, T1
Tomoda, Y1
Olson, DM1
Kramar, D1
Smieja, Z1
Karl, PI1
Chang, B1
Fisher, SE1
Barnes, TR1
Katona, CL1
Poyser, NL1
Vanderpuye, OA1
Edwards, HC1
Booth, AG1
Dölle, W1
Smol'nikova, NM1
Strekalova, SN1
Artem'eva, NS1
Marois, M1
Marois, G1
Daly, RJ1
Kane, FJ1
Ewing, JA1
Varavudhi, P1
Behrman, S1
Shapiro, IuL1
Vaĭntrub, MIa1
Grinberg, KN1
Zhurkov, VS1
Gauron, EF3
Rowley, VN3
Hussain, MZ1
Harinath, M1
Murphy, J1
Ravel, R1
Riekers, HG1
Goldstein, BJ1
Gamboa, ET1
Isaacs, G1
Harter, DH1
Margulies, AI1
Berris, B1
Bergamaschi, P1
Berlingieri, D1
Vince, DJ1
Bindon, BM1

Reviews

1 review available for trifluoperazine and Pregnancy

ArticleYear
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent

1972

Other Studies

61 other studies available for trifluoperazine and Pregnancy

ArticleYear
Calmodulin activation is required for the enhancement of hippocampal neurogenesis following environmental enrichment.
    Neurological research, 2009, Volume: 31, Issue:7

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Calmodulin; Cell Co

2009
Mirtazapine use in two pregnant women: is it safe?
    Teratology, 2002, Volume: 66, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Depression; Drug Therapy, Combination; Female; Fol

2002
Trifluoperazine in nausea and vomiting of pregnancy.
    Canadian Medical Association journal, 1959, Jul-01, Volume: 81, Issue:1

    Topics: Female; Humans; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Trifluoperazine; Vomitin

1959
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
    The New Zealand medical journal, 1963, Volume: 62

    Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundi

1963
A STUDY OF THE HORMONAL REQUIREMENTS FOR OVUM IMPLANTATION IN THE RAT, BY MEANS OF DELAYED NIDATION-INDUCING SUBSTANCES (CHLORPROMAZINE, TRIFLUOPERAZINE).
    The Journal of endocrinology, 1963, Volume: 27

    Topics: Castration; Chlorpromazine; Embryo Implantation; Embryo Implantation, Delayed; Estradiol; Female; Hu

1963
[TERATOGENIC SUBSTANCES?].
    Medizinische Klinik, 1964, Jan-31, Volume: 59

    Topics: Abnormalities, Drug-Induced; Ectromelia; Fetal Diseases; Infant, Newborn; Meclizine; Phenmetrazine;

1964
[TERSTOGENIC SUBSTANCES?].
    Medizinische Klinik, 1963, Dec-13, Volume: 58

    Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meclizine; Ph

1963
MODIFIED IMMUNOLOGIC TEST FOR PREGNANCY.
    Technical bulletin of the Registry of Medical Technologists. American Society of Clinical Pathologists. Registry of Medical Technologists, 1964, Volume: 34

    Topics: Antigen-Antibody Reactions; Biomedical Research; Chlorpromazine; Chorionic Gonadotropin; Female; Gon

1964
MODIFIED IMMUNOLOGIC TEST FOR PREGNANCY.
    American journal of clinical pathology, 1964, Volume: 42

    Topics: Agglutination; Chlorpromazine; Chorionic Gonadotropin; Diagnosis, Differential; Female; Gonadotropin

1964
Side-effects of phenothiazines.
    British medical journal, 1967, Apr-01, Volume: 2, Issue:5543

    Topics: Adult; Female; Fluphenazine; Humans; Male; Movement Disorders; Perphenazine; Pregnancy; Trifluoperaz

1967
Pharmacogenic and psychogenic aspects of galactorrhea: case report.
    The American journal of psychiatry, 1980, Volume: 137, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Galactorrhea; Humans; Lactation Disorders; Menopaus

1980
Increased serum prolactin levels during phenothiazine and butyrophenone treatment of six postpartum women.
    Psychoneuroendocrinology, 1980, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Humans; Pregnancy; Pro

1980
Calmodulin and cyclic nucleotide-phosphodiesterase activities in rat mammary gland during the lactogenic cycle.
    FEBS letters, 1981, Dec-21, Volume: 136, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium-Binding P

1981
[Role of Ca2+ in the secretion of milk caseins in lactating rabbit mammary epithelial cells].
    Biology of the cell, 1983, Volume: 49, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Calcium; Caseins; Epithe

1983
The modulation of placental lactogen secretion by calcium: studies with cultured human term trophoblast.
    Molecular and cellular endocrinology, 1984, Volume: 37, Issue:3

    Topics: Calcimycin; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Female; Humans; Placental Lacto

1984
Calcium-ion and calmodulin-dependent kappa-casein kinase in rat mammary acini.
    The Biochemical journal, 1984, Nov-15, Volume: 224, Issue:1

    Topics: Animals; Calcium; Calmodulin; Casein Kinases; Electrophoresis, Polyacrylamide Gel; Female; In Vitro

1984
Inhibition by calmodulin antagonists of glioblast DNA synthesis and morphological changes induced by glia maturation factor.
    Brain research, 1982, Volume: 255, Issue:4

    Topics: Animals; Brain; Calcium-Binding Proteins; Calmodulin; Cattle; Cells, Cultured; DNA Replication; Fema

1982
Dopamine-inhibited adenylate cyclase in female rat adenohypophysis.
    Life sciences, 1981, Apr-06, Volume: 28, Issue:14

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Dopamine; Female; Kinetics; Lactation; Male; Nore

1981
Overdosage of misoprostol in pregnancy.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:2

    Topics: Abortion, Criminal; Adult; Drug Overdose; Female; Humans; Misoprostol; Pregnancy; Suicide, Attempted

1994
Extracellular calcineurin: identification and quantitation in serum and amniotic fluid.
    Clinical biochemistry, 1999, Volume: 32, Issue:6

    Topics: Adult; Amniotic Fluid; Blotting, Western; Calcineurin; Calibration; Calmodulin; Cross Reactions; Enz

1999
Potassium depolarization-induced cAMP stimulates somatostatin mRNA levels in cultured diencephalic neurons.
    Brain research, 2000, Jun-23, Volume: 868, Issue:2

    Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Membrane; Cells, Cultured; Cycli

2000
Brom-ergocryptine in the treatment of phenothiazine-induced galactorrhoea.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: 126

    Topics: Adult; Amenorrhea; Amitriptyline; Antipsychotic Agents; Ergot Alkaloids; Female; Follicle Stimulatin

1975
Transient left bundle branch block in a neonate.
    Indian pediatrics, 1977, Volume: 14, Issue:9

    Topics: Bundle-Branch Block; Female; Humans; Imipramine; Infant, Newborn; Infant, Newborn, Diseases; Materna

1977
Fetal alcohol damage and schizophrenia.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10

    Topics: Adolescent; Brain; Female; Fetal Alcohol Spectrum Disorders; Humans; Pregnancy; Risk; Schizophrenia;

1978
Effect of certain drugs in perfused human placenta XII: autacoid antagonism by phenothiazines.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:10

    Topics: Angiotensin II; Blood Pressure; Bradykinin; Chlorpromazine; Female; Humans; In Vitro Techniques; Phe

1976
The role of calcium in DNA synthesis and development of mouse preimplantation embryos in vitro.
    Folia biologica, 1992, Volume: 40, Issue:3-4

    Topics: Animals; Calcium; DNA; Ectogenesis; Embryonic Development; Female; Mice; Pregnancy; Trifluoperazine

1992
Possible mechanisms of type I collagen-induced vascular tube formation.
    EXS, 1992, Volume: 61

    Topics: Cell Adhesion; Cells, Cultured; Chlorpromazine; Collagen; Endothelium, Vascular; Female; Humans; Imm

1992
Investigation of striatal dopamine D2 receptor acquisition following prenatal neuroleptic exposure.
    Psychiatry research, 1991, Volume: 36, Issue:3

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Dr

1991
Organic amnestic disorder: a long-term sequel after neuroleptic malignant syndrome.
    Biological psychiatry, 1991, Feb-15, Volume: 29, Issue:4

    Topics: Adult; Amnesia; Cerebral Cortex; Electroencephalography; Female; Follow-Up Studies; Humans; Infant,

1991
Effects of calmodulin antagonists on calcium-activated potassium channels in pregnant rat myometrium.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Animals; Calcium; Calmodulin; Cytoplasm; Egtazic Acid; Electrophysiology; Female; Membrane Potential

1990
Erotomania in relation to childbirth.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Adult; Female; Humans; Neurocognitive Disorders; Pregnancy; Puerperal Disorders; Transference, Psych

1990
Interrelated calcium ion and cyclic AMP inhibition of placental lactogen secretion by cultured human term trophoblast.
    Acta endocrinologica, 1987, Volume: 114, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bucladesine; Calcimycin; Calcium; Calcium Channel Blockers; Cel

1987
Control of bovine placental progesterone synthesis: roles of cholesterol availability and calcium-activated systems.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cholesterol; Drug Interactions; F

1988
Dihydropyridine receptors in the pregnant human uterus in vitro.
    Pharmacology, 1989, Volume: 39, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Progesterone production by binucleate trophoblastic cells of cows.
    Journal of reproduction and fertility. Supplement, 1989, Volume: 37

    Topics: Aminoglutethimide; Animals; Calcimycin; Calcium; Calmodulin; Cattle; Cells, Cultured; Cholesterol, H

1989
Contractile properties of chemically skinned fibers from pregnant rat myometrium: existence of an internal Ca-store.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 411, Issue:3

    Topics: Animals; Calcimycin; Calcium; Cations, Divalent; Choline; Cyclic AMP; Female; Inositol 1,4,5-Trispho

1988
ATP-dependent calcium transport across basal plasma membranes of human placental trophoblast.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 1

    Topics: Adenosine Triphosphate; Biological Transport, Active; Calcimycin; Calcium; Calcium-Transporting ATPa

1987
Teratogenic effect of trifluoperazine in rats and mice.
    Acta biologica Hungarica, 1985, Volume: 36, Issue:3-4

    Topics: Animals; Cleft Palate; Female; Mice; Micrognathism; Pregnancy; Rats; Rats, Inbred Strains; Teratogen

1985
The roles of Ca2+ and adenosine 3',5'-monophosphate in the regulation of progesterone production by human placental tissue.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 65, Issue:1

    Topics: Calcimycin; Calcium; Calmodulin; Cyclic AMP; Female; Humans; Isoproterenol; Placenta; Pregnancy; Pro

1987
Identification of calmodulin-like activity in term human amnion: effect of calmodulin inhibitors on prostaglandin biosynthesis.
    Journal of developmental physiology, 1987, Volume: 9, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amnion; Calcimycin; Calcium; Calmodulin; Cytosol; Dinoprostone;

1987
Calcium-sensitive uptake of amino acids by human placental slices.
    Pediatric research, 1988, Volume: 23, Issue:1

    Topics: Amino Acids, Branched-Chain; Biological Transport; Calcium; Egtazic Acid; Female; Humans; In Vitro T

1988
Susceptibility to drug-induced hypotension in post-partum psychosis.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:1

    Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Pimozide; Pregnancy; Psychotic Diso

1986
Prostaglandin output from the early pregnant rat uterus superfused in vitro, and the effect of A23187 and trifluoperazine.
    Journal of reproduction and fertility, 1985, Volume: 74, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Dinoprost; Dinoprostone; Female; Organ Culture Te

1985
Proteins of the human placental microvillar cytoskeleton. alpha-Actinin.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Actinin; Calcium; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Female; Humans; Microvilli; Pla

1986
Calmodulin-dependent protein kinase in acini from lactating rat mammary tissue: subcellular locale, characterization, and solubilization.
    Archives of biochemistry and biophysics, 1985, Aug-01, Volume: 240, Issue:2

    Topics: Animals; Calcium; Calmodulin; Centrifugation, Density Gradient; Chromatography, Gel; Electrophoresis

1985
[Herpes simplex hepatitis in the adult].
    Der Internist, 1972, Volume: 13, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Antigens, Viral; Chemical and Drug Induced Liver Injury; Chloramphen

1972
Effect of psychopharmacological agents on the gonads of female rats.
    Bulletin of experimental biology and medicine, 1974, Volume: 77, Issue:3

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Estrus; Female; Ovary; Phenothiazines; Pregnancy; Rat

1974
[Psychotropic drugs, ovarian functions and mammary activity (author's transl)].
    Steroids and lipids research, 1974, Volume: 5, Issue:4

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Estrus; Female; Mammary Glands, Animal; Ovary; Phenot

1974
Psychosis associated with the use of a sequential oral contraceptive.
    Lancet (London, England), 1967, Aug-26, Volume: 2, Issue:7513

    Topics: Adult; Chlormadinone Acetate; Chlorpromazine; Contraceptives, Oral; Depression; Estrogens; Female; H

1967
Induction by androgens of nidation in pregnant rats deprived of gonadotrophin secretion by trifluoperazine injections and by lactation.
    The Journal of endocrinology, 1969, Volume: 43, Issue:2

    Topics: Adrenalectomy; Androgens; Animals; Castration; Dehydroepiandrosterone; Embryo Implantation; Female;

1969
Mutism induced by phenothiazines.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:565

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Depression; Female; Humans; Hyperemesis Gravidarum; Int

1972
Effects on offspring behavior of parental early drug experience and cross-fostering.
    Psychopharmacologia, 1973, Jun-19, Volume: 30, Issue:3

    Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Conditioning, Psyc

1973
Tranquillizer-induced galactorrhea.
    Canadian Medical Association journal, 1972, May-20, Volume: 106, Issue:10

    Topics: Adolescent; Amitriptyline; Chlorprothixene; Diazepam; Female; Haloperidol; Humans; Lactation Disorde

1972
Effects of chronic trifluoperazine administration in multiple dosages on rat offspring behavior.
    Psychological reports, 1971, Volume: 29, Issue:2

    Topics: Animals; Avoidance Learning; Body Weight; Female; Male; Pregnancy; Rats; Rats, Inbred Strains; Sex F

1971
Effects on offspring behavior of mothers' early chronic drug experience.
    Psychopharmacologia, 1969, Volume: 16, Issue:1

    Topics: Animals; Animals, Newborn; Avoidance Learning; Breeding; Chlorpromazine; Conditioning, Psychological

1969
Effects of certain psychotropic drugs on immunologic pregnancy tests.
    American journal of obstetrics and gynecology, 1969, Dec-15, Volume: 105, Issue:8

    Topics: Chlorpromazine; Chlorprothixene; Chorionic Gonadotropin; False Positive Reactions; Female; Fluphenaz

1969
Chorea associated with oral contraceptive therapy.
    Archives of neurology, 1971, Volume: 25, Issue:2

    Topics: Adult; Chlorpromazine; Chorea; Contraceptives, Oral; Female; Humans; Mestranol; Norethindrone; Penic

1971
Jaundice associated with the administration of trifluoperazine.
    Canadian Medical Association journal, 1968, Jun-01, Volume: 98, Issue:22

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Jaundice; Pregnancy; Schizophrenia; T

1968
[Neuroleptic treatment at the onset of pregnancy and sacro-coccygeal teratoma of the fetus].
    Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise, 1968, Volume: 20, Issue:5

    Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Sacrococcygeal Region; Tera

1968
Congenital malformations following phenothiazine administration during pregnancy.
    Canadian Medical Association journal, 1969, Jan-25, Volume: 100, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Animals; Female; Heart Defects, Congenital; Heart Septal Defects

1969
The role of the pituitary gland in implantation in the mouse: delay of implantation by hypophysectomy and neurodepressive drugs.
    The Journal of endocrinology, 1969, Volume: 43, Issue:2

    Topics: Animals; Chlorpromazine; Copulation; Embryo Implantation; Embryo, Mammalian; Estrus; Female; Gonadot

1969