Page last updated: 2024-08-05 13:40:37

thienotriazolodiazepine

Any organic heterotricyclic compound constructed from fused thiophene, triazole and diazepeine rings.

ChEBI ID: 84232

Members (2)

MemberDefinitionRole
jq1 compoundA member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties.JQ1
MS-417A member of the class of thienotriazolodiazepines that is the methyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. A bromodomain and extra-terminal domain (BET)-specific inhibitor that belongs to a group of thienodiazepine-based compoundsMS-417

Research

Studies (113)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's68 (60.18)24.3611
2020's45 (39.82)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews8 (7.02%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other106 (92.98%)84.16%