A substance that prevents pests from feeding.
ChEBI ID: 22583
| Member | Definition | Class |
|---|---|---|
| 3-octanone | A dialkyl ketone that is octane in which the two methylene protons at position 3 have been replaced by an oxo group. | 3-octanone |
| 6-deacetylnimbin | A limonoid that is nimbin in which the acetyloxy group at position 6 is replaced by a hydroxy hroup. It has been isolated from Azadirachta indica. | 6-deacetylnimbin |
| albicanol | A drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities. | (+)-albicanol |
| allyl cyanide | An aliphatic nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an allyl group. | allyl cyanide |
| decamethrin | A cyclopropanecarboxylate ester obtained by formal condensation between 3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol. It is the active insecticide of the proinsecticide tralomethrin. | deltamethrin |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| pelargonic acid | A C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers. | nonanoic acid |
| primin | A 1,4-benzoquinone having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position. | primin |
| pymetrozine | A member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2H)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4. | pymetrozine |
| salannin | A limonoid with insecticidal activity isolated from Azadirachta indica. | salannin |
| thiamethoxam | An oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively. | thiamethoxam |
| viridiflorol | A carbotricyclic compound that is (1aS,4aR,7aR,7bR)-decahydro-1H-cyclopropa[e]azulene carrying four methyl substituents at positions 1, 1, 4 and 7 as well as a hydroxy substituent at position 4. It is a sesquiterpenoid isolated from several plant species and is a strong feeding deterrent for the melaleuca weevil that retards larval development. | viridiflorol |
| yunaconitine | A diterpene alkaloid with formula C35H49NO11 that is isolated from several Aconitum species. | yunaconitine |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 179 (5.57) | 18.7374 |
| 1990's | 276 (8.58) | 18.2507 |
| 2000's | 630 (19.60) | 29.6817 |
| 2010's | 1,464 (45.54) | 24.3611 |
| 2020's | 666 (20.72) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 66 (1.96%) | 5.53% |
| Reviews | 41 (1.22%) | 6.00% |
| Case Studies | 19 (0.56%) | 4.05% |
| Observational | 2 (0.06%) | 0.25% |
| Other | 3,237 (96.20%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 46.7614 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 51.0665 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 25.1705 | 5 | 5 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 50.1621 | 2 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 64.9647 | 2 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.5995 | 3 | 7 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 47.0310 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 37.7822 | 6 | 16 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 30.4517 | 2 | 3 |
| geminin | Homo sapiens (human) | Potency | 14.9564 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 39.3581 | 5 | 7 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 58.9041 | 2 | 4 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 56.0640 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 42.0372 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 29.5292 | 1 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 52.2353 | 3 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 8.3545 | 2 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 17.6262 | 2 | 4 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 58.2546 | 2 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 13.4227 | 3 | 5 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 42.9572 | 2 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 46.3035 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 46.3035 | 2 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 69.9313 | 2 | 2 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 8.3868 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 17.2289 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 31.6316 | 1 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 4.7419 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 90.0000 | 1 | 3 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 1.3700 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 18.9200 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 1.9000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| G-protein coupled receptor 84 | Homo sapiens (human) | EC50 | 61.2500 | 2 | 2 |