Page last updated: 2024-09-27

Korsakoff Psychosis

An acquired cognitive disorder characterized by inattentiveness and the inability to form short term memories. This disorder is frequently associated with chronic ALCOHOLISM; but it may also result from dietary deficiencies; CRANIOCEREBRAL TRAUMA; NEOPLASMS; CEREBROVASCULAR DISORDERS; ENCEPHALITIS; EPILEPSY; and other conditions. (Adams et al., Principles of Neurology, 6th ed, p1139)

Synonyms(3)

Synonym
Wernicke-Korsakoff Syndrome
Korsakoff Syndrome
Korsakoff Psychosis

Research Excerpts

Overview

ExcerptReference
"Korsakoff syndrome is a serious disorder, responsible for cognitive handicap."( Verstichel, P, 2000)
"Wernicke-Korsakoff syndrome is a condition with high morbidity and mortality and occurs as a consequence of thiamine deficiency."( Nilsson, M; Sonne, C, 2013)
"Korsakoff syndrome is a chronic form of amnesia resulting from thiamine deficiency."( Beuman, C; Bresser, EL; Gerridzen, IJ; Mulder, CL; Oudman, E; van de Wiel, A; Wijnia, JW, 2014)
"Korsakoff syndrome is a chronic memory disorder caused by a severe deficiency of thiamine that is most commonly observed in alcoholics."( Barkan, AL; Hollon, TC; Savastano, LE; Sullivan, SE, 2018)
"Wernicke-Korsakoff syndrome is a type of brain disorder caused by the lack of thiamine, most commonly because of chronic alcohol misuse."( Genç, A; Küçükdeveci, AA; Moustafa, E; Özdemir, EC, 2018)
"Wernicke-Korsakoff syndrome is the best known consequence of thiamine deficiency, frequently associated with patients with chronic and excessive alcohol consumption, but it can be produced by any cause that produces thiamine deficiency."( Chamorro, AJ; Marcos, M; Mateos-Díaz, AM, 2022)
"Wernicke-Korsakoff syndrome is a neuropsychiatric disorder caused by thiamine deficiency composed of two related disorders accounting for an acute presentation and chronic progression."( Becker, M; DeSimone, A; Lopez-Pastrana, J; Olmsted, A, 2023)

Research

Studies (119)

TimeframeStudies, This Condition (%)All Conditions %
pre-199010 (8.40)23.3326
1990's5 (4.20)12.5806
2000's38 (31.93)18.1394
2010's42 (35.29)28.8240
2020's24 (20.17)9.53
DrugIndicatedRelationship StrengthStudiesTrials
protocatechuic acid0low10
gamma-aminobutyric acid0low10
carbon monoxide0low10
choline0low10
niacin0medium31
thiamine0medium672
4-iodo-2,5-dimethoxyphenylisopropylamine0low10
amobarbital0low10
antipyrine0low10
bromisovalum0low10
carbamazepine0low10
chlordiazepoxide0low10
chlorpromazine0low10
citalopram0low10
clonidine0low10
diazepam0low10
donepezil0low20
fenfluramine0low10
foscarnet0low10
glutethimide0low10
propyphenazone0low10
ketanserin0low10
meclofenoxate0low10
memantine0medium31
muscimol0low10
phenobarbital0low10
risperidone0low20
thioridazine0low10
trifluoperazine0low10
prednisone0low10
glutamine0low10
physostigmine0low30
bromodeoxyuridine0low10
cytarabine0low10
phenothiazine0low10
thiamine pyrophosphate0low40
pyrithiamine0low130
s,n,n'-tripropylthiocarbamate0low30
daunorubicin0low10
phenyl acetate0low20
glutamic acid0low10
etoposide0low10
cabergoline0low10
fluorodeoxyglucose f180low30
ertapenem0low10
retinol0low10
17-ketosteroids0low10
n-oleoylethanolamine0low10
fluvoxamine0low20
dizocilpine maleate0low10
scopolamine hydrobromide0low10
piperidines0low20
vitamin b 120low10
folic acid0low30
clozapine0low10
ganciclovir0low20
eye0low10

Protein Targets (818)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
GLS protein120012
atrial natriuretic peptide receptor 1 precursor3003
chromobox protein homolog 1120012
5-hydroxytryptamine receptor 1A06410
5-hydroxytryptamine receptor 2C09413
5-hydroxytryptamine receptor 2A09413
5-hydroxytryptamine receptor 1A016218
5-hydroxytryptamine receptor 2A011217
5-hydroxytryptamine receptor 2C015218
5-hydroxytryptamine receptor 1B011112
5-hydroxytryptamine receptor 1D0213
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 2B09413
5-hydroxytryptamine receptor 60011
5-hydroxytryptamine receptor 7 0415
5-hydroxytryptamine receptor 2C 0203
5-hydroxytryptamine receptor 2A0203
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 2B015218
5-hydroxytryptamine receptor 5A0303
5-hydroxytryptamine receptor 4 0011
Ataxin-2120012
5-hydroxytryptamine receptor 3B0112
TDP1 protein230023
AR protein240024
farnesoid X nuclear receptor5005
estrogen nuclear receptor alpha220022
ATAD5 protein, partial7007
USP1 protein, partial120012
GLI family zinc finger 3170017
nuclear receptor subfamily 1, group I, member 3170017
glucocorticoid receptor [Homo sapiens]180018
retinoic acid nuclear receptor alpha variant 1150015
retinoid X nuclear receptor alpha110011
67.9K protein5005
peroxisome proliferator-activated receptor delta8008
thyroid hormone receptor beta isoform a6006
nuclear factor erythroid 2-related factor 2 isoform 27007
nuclear factor erythroid 2-related factor 2 isoform 1130013
geminin190019
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015016
Bile salt export pump022022
Cytochrome P450 2C9 08110
Cytochrome P450 2J20506
Nicotinate phosphoribosyltransferase0101
Canalicular multispecific organic anion transporter 1016017
GALC protein2002
peripheral myelin protein 22160016
lamin isoform A-delta10170017
Spike glycoprotein141116
interleukin 83003
pregnane X receptor3003
RAR-related orphan receptor gamma120012
Microtubule-associated protein tau120012
aldehyde dehydrogenase 1 family, member A1120012
progesterone receptor100010
estrogen-related nuclear receptor alpha200020
pregnane X nuclear receptor140014
bromodomain adjacent to zinc finger domain 2B5005
arylsulfatase A110011
IDH17007
euchromatic histone-lysine N-methyltransferase 2220022
nuclear receptor subfamily 1, group I, member 21001
cellular tumor antigen p53 isoform a4004
Nuclear hormone receptor family member daf-120011
thyroid hormone receptor beta isoform 2160016
serine/threonine-protein kinase mTOR isoform 16006
oxysterols receptor LXR-beta isoform 10011
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
survival motor neuron protein isoform d9009
muscarinic acetylcholine receptor M18008
Voltage-dependent calcium channel gamma-2 subunit8008
Thymidine kinase, cytosolic0202
Glutamate receptor 282111
Thymidine phosphorylase0001
Thymidylate kinase0101
Nuclear receptor ROR-gamma3003
Thymidine kinase0001
Thymidylate kinase0101
ATPase family AAA domain-containing protein 56006
acetylcholinesterase120012
cytochrome P450 family 3 subfamily A polypeptide 4130013
cytochrome P450 2D6110011
thyroid stimulating hormone receptor9009
Cellular tumor antigen p53140014
Histamine H3 receptor0505
Chain A, Beta-lactamase3003
thyroid stimulating hormone receptor9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
mitogen-activated protein kinase 17007
Vpr1001
Bile salt export pump0505
Albumin0077
Major prion protein0022
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0203
Potassium voltage-gated channel subfamily H member 2016016
Sodium channel protein type 9 subunit alpha0303
Frizzled-80011
P2X purinoceptor 40101
glp-1 receptor, partial8008
potassium voltage-gated channel subfamily H member 2 isoform d140014
Gamma-aminobutyric acid receptor subunit pi109120
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit alpha-30303
Gamma-aminobutyric acid receptor subunit alpha-106410
Gamma-aminobutyric acid receptor subunit beta-1109120
Translocator protein0214
Gamma-aminobutyric acid receptor subunit delta109120
Gamma-aminobutyric acid receptor subunit gamma-20639
Gamma-aminobutyric acid receptor subunit gamma-2109221
Gamma-aminobutyric acid receptor subunit alpha-5109120
Gamma-aminobutyric acid receptor subunit alpha-3109120
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit gamma-1109120
Gamma-aminobutyric acid receptor subunit alpha-2109120
Gamma-aminobutyric acid receptor subunit alpha-4109120
Gamma-aminobutyric acid receptor subunit beta-30639
Gamma-aminobutyric acid receptor subunit gamma-3109120
Gamma-aminobutyric acid receptor subunit alpha-6109120
Cholecystokinin receptor type A0202
Gastrin/cholecystokinin type B receptor0202
Gamma-aminobutyric acid receptor subunit alpha-506410
Gamma-aminobutyric acid receptor subunit alpha-30639
Histamine H1 receptor013217
Gamma-aminobutyric acid receptor subunit alpha-20639
Gamma-aminobutyric acid receptor subunit alpha-1109221
Gamma-aminobutyric acid receptor subunit beta-3109120
Gamma-aminobutyric acid receptor subunit beta-2109221
GABA theta subunit109120
Gamma-aminobutyric acid receptor subunit epsilon109120
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Proteasome subunit beta type-110001
thioredoxin reductase130013
phosphopantetheinyl transferase8008
Fumarate hydratase4004
NFKB1 protein, partial5005
Thrombopoietin2002
Smad33003
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)8008
NADPH oxidase 10303
G8008
polyprotein4004
peroxisome proliferator activated receptor gamma7007
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
Snq2p0004
caspase-35005
Adenylate cyclase type 1 0303
v-jun sarcoma virus 17 oncogene homolog (avian)8008
Histone H2A.x100010
Caspase-73003
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cytochrome P450 2D6 isoform 15005
D(1A) dopamine receptor9009
vitamin D3 receptor isoform VDRA6006
caspase-33003
histone deacetylase 9 isoform 31001
heat shock protein beta-14004
atrial natriuretic peptide receptor 2 precursor4004
ras-related protein Rab-9A3003
DNA polymerase kappa isoform 14004
cytochrome P450 3A4 isoform 1100010
M-phase phosphoprotein 86006
histone acetyltransferase KAT2A isoform 16006
lethal factor (plasmid)7007
Proteasome subunit alpha type-70001
Solute carrier family 22 member 1 06010
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0303
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0303
Voltage-dependent L-type calcium channel subunit alpha-1F0606
5-hydroxytryptamine receptor 4012012
Potassium channel subfamily K member 20101
Epidermal growth factor receptor0202
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 8008
Albumin0124
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Integrin beta-33014
Cytochrome P450 1A20213
Tyrosine-protein kinase Fyn0202
Procathepsin L0112
Aldo-keto reductase family 1 member B1010010
Muscarinic acetylcholine receptor M20819
Muscarinic acetylcholine receptor M409110
ATP-dependent translocase ABCB107013
Muscarinic acetylcholine receptor M10606
Muscarinic acetylcholine receptor M30505
Muscarinic acetylcholine receptor M40505
Integrin alpha-IIb3014
Muscarinic acetylcholine receptor M50505
Muscarinic acetylcholine receptor M50808
Alpha-2A adrenergic receptor010111
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Cys-loop ligand-gated ion channel0101
Calmodulin-10325
Replicase polyprotein 1ab0213
Cytochrome P450 2D60618
Muscarinic acetylcholine receptor M20718
Muscarinic acetylcholine receptor M109110
Polyunsaturated fatty acid lipoxygenase ALOX150303
Angiotensin-converting enzyme012012
D(2) dopamine receptor09013
Alpha-1B adrenergic receptor012214
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor010111
Alpha-2C adrenergic receptor010111
D0909
D(3) dopamine receptor0808
Alpha-2B adrenergic receptor0819
D(2) dopamine receptor0303
Muscarinic acetylcholine receptor M309110
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor08010
D(4) dopamine receptor08011
D(1B) dopamine receptor0204
Adenylate cyclase type 30303
Alpha-2C adrenergic receptor0819
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0819
Alpha-1D adrenergic receptor010212
Sodium-dependent noradrenaline transporter 012012
Sodium-dependent dopamine transporter0707
Histamine H2 receptor0808
Alpha-1D adrenergic receptor012113
D(1B) dopamine receptor0707
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20303
Adenylate cyclase type 40303
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
Trypanothione reductase0404
D(4) dopamine receptor0707
Histamine H1 receptor0404
Sodium-dependent serotonin transporter016117
Melanocortin receptor 40202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0408
5-hydroxytryptamine receptor 70505
Mu-type opioid receptor0202
Glutamate receptor ionotropic, NMDA 1 0618
D(3) dopamine receptor08011
Sodium channel protein type 1 subunit alpha0202
Adenylate cyclase type 80303
Proteasome subunit beta type-100001
Delta-type opioid receptor0202
Kappa-type opioid receptor0404
Melanocortin receptor 30202
Alpha-1A adrenergic receptor013316
Histamine H2 receptor8009
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60809
5-hydroxytryptamine receptor 70505
Gastrin/cholecystokinin type B receptor0202
Proteasome subunit alpha type-60023
D(2) dopamine receptor013115
Calmodulin 0134
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0618
Glutamate receptor ionotropic, NMDA 2B0618
Glutamate receptor ionotropic, NMDA 2C0618
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0606
Sodium-dependent dopamine transporter 010010
Adenylate cyclase type 60303
Adenylate cyclase type 50303
Glutamate receptor ionotropic, NMDA 10404
Aldehyde oxidase0204
Glutamate receptor ionotropic, NMDA 2A0404
Glutamate receptor ionotropic, NMDA 2B0404
Voltage-dependent L-type calcium channel subunit alpha-1S0606
Voltage-dependent L-type calcium channel subunit alpha-1C0606
Sodium channel protein type 5 subunit alpha0404
Glutamate receptor ionotropic, NMDA 2C0303
Glutamate receptor ionotropic, NMDA 2D0618
Nuclear receptor subfamily 3 group C member 3 012012
Adenylyl cyclase 7 0303
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0303
Glutamate receptor ionotropic, NMDA 3B0618
Inositol hexakisphosphate kinase 18008
D0303
Sodium channel protein type 2 subunit alpha0202
Proteasome subunit beta type-70001
Sigma non-opioid intracellular receptor 1011011
Angiotensin-converting enzyme 2 0112
Sodium channel protein type 3 subunit alpha0202
Glutamate receptor ionotropic, NMDA 3A0618
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial8008
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20103
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30202
Neuronal acetylcholine receptor subunit alpha-41203
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-21203
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase09314
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0102
Neuronal acetylcholine receptor subunit alpha-60202
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70202
Solute carrier family 22 member 10304
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20203
ATP-dependent phosphofructokinase110011
EWS/FLI fusion protein7007
NPC intracellular cholesterol transporter 1 precursor3003
Sodium-dependent noradrenaline transporter0101
Tryptophan 5-hydroxylase 10303
Aldo-keto reductase family 1 member B10101
Aromatase0101
Sodium-dependent serotonin transporter0415
Sigma intracellular receptor 20202
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Sigma non-opioid intracellular receptor 10404
Transporter0505
Chain A, Ferritin light chain5005
Chain A, Cruzipain3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
regulator of G-protein signaling 45005
Beta-1 adrenergic receptor 0112
Alpha-1B adrenergic receptor 0011
cytochrome P450 2C19 precursor8008
cytochrome P450 2C9 precursor4004
Membrane primary amine oxidase 0101
5-hydroxytryptamine receptor 3A0112
Solute carrier family 22 member 30202
Alpha-1A adrenergic receptor0011
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0202
Adenosine receptor A2b0011
Adenosine receptor A2a0011
Alpha-2B adrenergic receptor0001
Delta-type opioid receptor0404
Alpha-1A adrenergic receptor0415
Alpha-1B adrenergic receptor0314
Mu-type opioid receptor0101
Inositol monophosphatase 15005
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Multidrug and toxin extrusion protein 10303
Nischarin0101
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, JmjC domain-containing histone demethylation protein 3A5005
5-hydroxytryptamine receptor 3E0101
Luciferase4004
hypoxia-inducible factor 1 alpha subunit4004
glucocerebrosidase3003
Bloom syndrome protein isoform 17007
peripheral myelin protein 22 isoform 13003
DNA polymerase beta5005
DNA polymerase iota isoform a (long)9009
nuclear receptor ROR-gamma isoform 15005
short transient receptor potential channel 6 isoform 10011
transient receptor potential cation channel subfamily V member 11001
5-hydroxytryptamine receptor 3B0101
Cytochrome P450 3A40719
Beta-2 adrenergic receptor0202
Beta-1 adrenergic receptor0202
Endothelin receptor type B0101
5-hydroxytryptamine receptor 3A0101
Endothelin receptor type B0101
Adenosine receptor A10101
Beta-3 adrenergic receptor0101
Histamine H1 receptor0303
Cytochrome P450 2C190102
5-hydroxytryptamine receptor 3A0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
D(2) dopamine receptor0101
D(3) dopamine receptor0101
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 40101
Transporter0202
Cholecystokinin receptor type A0101
5-hydroxytryptamine receptor 1A0202
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
Histamine H4 receptor0112
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
endonuclease IV3003
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0101
Thymidylate synthase0102
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
PPM1D protein1001
aryl hydrocarbon receptor3003
activating transcription factor 66006
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
huntingtin isoform 23003
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
Transthyretin0101
NADH-ubiquinone oxidoreductase chain 40001
72 kDa type IV collagenase0202
DNA topoisomerase 2-alpha0118
Carbonyl reductase [NADPH] 10001
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Platelet-activating factor receptor1001
Multidrug resistance-associated protein 1 0203
Histone deacetylase 10202
Reverse transcriptase/RNaseH 0213
Histone deacetylase 80202
Histone deacetylase 60202
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Gamma-aminobutyric acid 0112
Gamma-aminobutyric acid receptor subunit pi0505
Gamma-aminobutyric acid receptor subunit delta0505
Fatty acid-binding protein, liver0101
Alpha-1-acid glycoprotein 10001
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit beta-10527
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Translocator protein0101
Translocator protein0101
Gamma-aminobutyric acid receptor subunit beta-20538
Gamma-aminobutyric acid receptor subunit alpha-40527
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit epsilon0505
Gamma-aminobutyric acid receptor subunit alpha-60527
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit gamma-10505
Gamma-aminobutyric acid receptor subunit pi0112
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30505
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit theta0112
Gamma-aminobutyric acid receptor subunit gamma-10112
Gamma-aminobutyric acid receptor subunit theta0505
Acetylcholinesterase09010
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Acetylcholinesterase0505
Amyloid-beta precursor protein0303
Cholinesterase0707
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0505
Liver carboxylesterase 10101
Acetylcholinesterase 0505
Acetylcholinesterase0404
Glycogen synthase kinase-3 beta0101
Beta-secretase 10202
Cholinesterase08110
Cholinesterase0303
Acetylcholine receptor subunit epsilon0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Cytochrome P450 1B10101
Sigma non-opioid intracellular receptor 10101
Acyl-CoA:cholesterol acyltransferase 0202
Carboxylic ester hydrolase 0303
Carboxylic ester hydrolase 0606
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase class B VIM-2 0001
SMAD family member 23003
SMAD family member 33003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
Prothrombin0012
Regulatory protein E20011
ATP-dependent translocase ABCB10101
DNA topoisomerase 10102
DNA topoisomerase 20001
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0001
Serum paraoxonase/arylesterase 10101
Caspase-30101
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Tubulin beta-2B chain0101
Integrase 0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Solute carrier organic anion transporter family member 1B30203
Cytochrome P450 1A2 0101
Chain A, Dihydrofolate reductase0011
acid sphingomyelinase1001
alpha-galactosidase2002
lysosomal alpha-glucosidase preproprotein4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Thymidylate synthase0202
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Alpha-synuclein1304
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Chain A, probable fosfomycin resistance protein0011
Chain B, probable fosfomycin resistance protein0011
Carbonic anhydrase 10205
Carbonic anhydrase 20305
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase alpha catalytic subunit0101
Carbonic anhydrase 40202
DNA polymerase delta catalytic subunit0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 90202
Chain A, ACETYLCHOLINESTERASE0101
Chain A, Acetylcholinesterase0101
Vascular endothelial growth factor receptor 1 0101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Kappa-type opioid receptor0101
Prolyl endopeptidase0101
Small conductance calcium-activated potassium channel protein 30101
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
transcriptional regulator ERG isoform 32002
neuropeptide S receptor isoform A1001
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit rho-10044
Gamma-aminobutyric acid receptor subunit rho-20022
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 431001
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Platelet glycoprotein VI0022
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Thymidine kinase 0101
ClpP1001
POU domain, class 2, transcription factor 20001
Transitional endoplasmic reticulum ATPase0101
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60001
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
ATP-citrate synthase 0101
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Glutamine Binding Protein0011
15-lipoxygenase, partial4004
flap endonuclease 12002
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
dopamine D1 receptor1001
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
Synaptic vesicular amine transporter0202
Vesicular acetylcholine transporter0101
POU domain, class 2, transcription factor 10001
D-amino-acid oxidase0101
5-hydroxytryptamine receptor 1B0101
nonstructural protein 12002
FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)0001
heat shock protein HSP 90-alpha isoform 20001
tumor susceptibility gene 101 protein1001
DNA polymerase eta isoform 11001
Renin0011
Cytochrome P450 2C80011
Fatty acid-binding protein, liver0101
Cannabinoid receptor 10101
Cannabinoid receptor 10303
Cannabinoid receptor 2 0101
Cannabinoid receptor 10011
Cannabinoid receptor 20011
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor alpha0011
Corticotropin-releasing factor receptor 20101
Acid ceramidase0202
Glucose-dependent insulinotropic receptor0011
Transient receptor potential cation channel subfamily V member 10011
Glucose-dependent insulinotropic receptor0011
Rap guanine nucleotide exchange factor 41001
Transient receptor potential cation channel subfamily V member 20101
heat shock protein 90, putative0001
thyrotropin-releasing hormone receptor1001
Polyphenol oxidase 20202
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Solute carrier organic anion transporter family member 1B10001
apical membrane antigen 1, AMA12002
polyunsaturated fatty acid lipoxygenase ALOX121001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
rac GTPase-activating protein 1 isoform a0101
muscleblind-like protein 1 isoform 11001
Adenosine receptor A30202
Polyunsaturated fatty acid 5-lipoxygenase0101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Acetylcholinesterase0101
thioredoxin glutathione reductase1001
Glucocorticoid receptor0213
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Chain A, Protocatechuate 3,4-dioxygenase alpha chain0011
Chain B, Protocatechuate 3,4-dioxygenase beta chain0011
M18 aspartyl aminopeptidase0101
cathepsin L10101
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Carbonic anhydrase 120101
Rap guanine nucleotide exchange factor 31001
3-dehydroquinate synthase0101
Matrilysin0101
Prolyl 4-hydroxylase subunit alpha-10101
Carbonic anhydrase 60202
Carbonic anhydrase 70101
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60101
Alpha-glucosidase MAL120101
Anthrax toxin receptor 20101
Xanthine dehydrogenase/oxidase0101
Alpha-(1,3)-fucosyltransferase 70101
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10101
Carbonic anhydrase0101
Dihydroorotate dehydrogenase 0101
Carbonic anhydrase 140101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 171001
Glycine receptor subunit alpha-10011
Multidrug and toxin extrusion protein 20101
Acyl-CoA desaturase 10101
Acetylcholine receptor subunit epsilon0101
Cholinesterase0101
Tyrosine-protein kinase SYK0101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
1-deoxy-D-xylulose-5-phosphate synthase0011
1-deoxy-D-xylulose-5-phosphate synthase0011
Parkin1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Cathepsin D 0101
Mucosa-associated lymphoid tissue lymphoma translocation protein 10101
Genome polyprotein 0101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
DNA repair protein RAD52 homolog isoform a0001
Ubiquitin carboxyl-terminal hydrolase 10101
Lysozyme C-10101
Glycoprotein hormones alpha chain1001
Protein kinase C alpha type0101
Beta-glucuronidase0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
C-8 sterol isomerase0101
Guanine nucleotide-binding protein G1001
Protein kinase C gamma type0101
Protein kinase C beta type0101
DNA-dependent protein kinase catalytic subunit0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Protein kinase C eta type0101
Calcium-dependent protein kinase 40101
WD repeat-containing protein 480101
Emopamil-binding protein-like0101
Protein kinase C theta type0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]