| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID692954 | Inhibition of Wnt/beta-casein in human LS174T cells assessed as reduction in Cyclin D1 protein level at 100 uM by Western blotting | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5
| Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. |
| AID200787 | In vitro growth inhibition of central nervous system SF-268 cell line. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID471946 | Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID781075 | Cytotoxicity against ER-positive human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23
| Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines. |
| AID642342 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 40 uM preincubated for 30 mins before LPS challenge measured after 24 hrs by Griess method | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID455030 | Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID642091 | Inhibition of human aromatase using dibenzylfluorescein as substrate preincubated for 30 mins measured after 2 hrs by fluorimetry | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID471948 | Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID336034 | Inhibition of bovine thymus p56LCK | 1993 | Journal of natural products, Oct, Volume: 56, Issue:10
| Kinase inhibitors from Polygonum cuspidatum. |
| AID490192 | Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 48 hrs | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
| Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. |
| AID642337 | Inhibition of TNFalpha-activated NF-kappaB expressed in HEK293 cells at 50 uM by luciferase reporter gene assay | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID57707 | In vitro growth inhibition of DU-145 (human prostate carcinoma) cell line. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID82976 | In vitro concentration required to induce apoptosis in HL60 cells | 2003 | Journal of medicinal chemistry, Jul-31, Volume: 46, Issue:16
| Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. |
| AID463401 | Antioxidant activity assessed as concentration required to double citronellal oxidation half life by thermo-oxidation method relative to control | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3
| A theoretical study of the structure-radical scavenging activity of trans-resveratrol analogues and cis-resveratrol in gas phase and water environment. |
| AID642328 | Induction of QR1 activity in mouse Hepa-1c1c7 cells using MTT as substrate assessed as induction ratio by spectrophotometry relative to control | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID150946 | In vitro inhibition of P388 (murine leukemia) cell proliferation. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID434137 | Inhibition of MAOB | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models. |
| AID642339 | Antioxidant activity assessed as DPPH free radical scavenging activity at 400 uM after 30 mins by spectrophotometry | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID490269 | Cell cycle arrest in human SW480 cells assessed as 4n cells at 30 uM after 48 hrs by flow cytometry | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
| Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. |
| AID642335 | Induction of QR1 activity in mouse BPrc1 cells using MTT as substrate by spectrophotometry | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID336035 | Inhibition of rat brain PKC | 1993 | Journal of natural products, Oct, Volume: 56, Issue:10
| Kinase inhibitors from Polygonum cuspidatum. |
| AID401039 | Antioxidant activity assessed as DPPH radical scavenging activity | 1998 | Journal of natural products, May, Volume: 61, Issue:5
| Isolation, identification, and antioxidant activity of three stilbene glucosides newly extracted from vitis vinifera cell cultures |
| AID455039 | Cytotoxicity against human OVCAR-3 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID490194 | Cell cycle arrest in human SW480 cells assessed as accumulation at S phase at 30 uM after 48 hrs by flow cytometry | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
| Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. |
| AID1238829 | Retention time of the compound in C57BL/6J mouse urine treated with RAH at 200 mg/kg, ig by HPLC-CEAD analysis | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16
| Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity. |
| AID455040 | Cytotoxicity against human A498 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID455036 | Cytotoxicity against human KM20L2 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID781076 | Stability of the compound in simulated gastric/intestinal fluid assessed as compound remaining at 10 mM after 6 hrs by UV/Vis spectroscopic analysis in presence of porcine pepsin and pancreatin relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23
| Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines. |
| AID471945 | Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID642334 | Induction of QR1 activity in mouse BPrc1 cells using MTT as substrate assessed as induction ratio by spectrophotometry relative to control | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID401040 | Antioxidant activity against cupric ion-induced lipid peroxidation in human LDL by TBA assay | 1998 | Journal of natural products, May, Volume: 61, Issue:5
| Isolation, identification, and antioxidant activity of three stilbene glucosides newly extracted from vitis vinifera cell cultures |
| AID103219 | Cell growth inhibition of breast MCF-7 cells, expressed as 50% reduction in the net protein increase | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID455037 | Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID471944 | Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID490270 | Cell cycle arrest in human SW480 cells assessed as >4n cells at 30 uM after 48 hrs by flow cytometry | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
| Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. |
| AID642331 | Induction of QR1 activity in mouse TAOc1 mutant Hepa cells using MTT as substrate assessed as induction ratio by spectrophotometry relative to control | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID455035 | Cytotoxicity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID146551 | In vitro growth inhibition of NCI-H460 (human non-small cell lung carcinoma) cell line. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID455034 | Cytotoxicity against human SF268 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID94870 | In vitro growth inhibition of KM20L2 cell line. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID455031 | Cytotoxicity against human BxPC3 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID82982 | In vitro inhibitory concentration against proliferation of HL60 cells | 2003 | Journal of medicinal chemistry, Jul-31, Volume: 46, Issue:16
| Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. |
| AID642090 | Inhibition of human aromatase using dibenzylfluorescein as substrate at 50 uM preincubated for 30 mins measured after 2 hrs by fluorimetry | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID642336 | Induction of QR1-mediated cytoprotective activity in mouse BPrc1 cells at 50 uM assessed as cell survival | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID490193 | Cell cycle arrest in human SW480 cells assessed as accumulation at G0/G1 phase at 30 uM after 48 hrs by flow cytometry | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
| Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. |
| AID471949 | Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID455033 | Cytotoxicity against human SF295 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID692953 | Inhibition of Wnt/beta-casein in human LS174T cells assessed as reduction in c-Myc protein level at 100 uM by Western blotting | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5
| Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. |
| AID642330 | Induction of QR1-mediated cytoprotective activity in mouse Hepa-1c1c7 cells at 50 uM assessed as cell survival | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID455032 | Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID642329 | Induction of QR1 activity in mouse Hepa-1c1c7 cells using MTT as substrate by spectrophotometry | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID40024 | In vitro growth inhibition of BXPC-3 (human pancreatic adenocarcinoma) cell line. | 2002 | Journal of medicinal chemistry, Jun-06, Volume: 45, Issue:12
| Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. |
| AID642333 | Induction of QR1-mediated cytoprotective activity in mouse TAOc1 mutant Hepa cells at 50 uM assessed as cell survival | 2012 | Bioorganic & medicinal chemistry, Jan-01, Volume: 20, Issue:1
| Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. |
| AID781074 | Cytotoxicity against ER-negative human SKBR3 cells assessed as growth inhibition after 72 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23
| Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines. |
| AID471947 | Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9
| Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. |
| AID455038 | Cytotoxicity against human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| AID977610 | Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB | 2015 | Nature, Mar-19, Volume: 519, Issue:7543
| A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |