null
ChEBI ID: 50510
| Member | Definition | Class |
|---|---|---|
| ezogabine | A substituted aniline that is benzene-1,2,4-triamine bearing ethoxycarbonyl and 4-fluorobenzyl substituents at positions N-1 and N-4 respectively. An anticonvulsant used to treat seizures associated with epilepsy in adults. | ezogabine |
| polydatin | A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue. | trans-piceid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (3.74) | 18.2507 |
| 2000's | 111 (27.68) | 29.6817 |
| 2010's | 222 (55.36) | 24.3611 |
| 2020's | 53 (13.22) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 26 (6.30%) | 5.53% |
| Reviews | 45 (10.90%) | 6.00% |
| Case Studies | 7 (1.69%) | 4.05% |
| Observational | 3 (0.73%) | 0.25% |
| Other | 332 (80.39%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 9.5221 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 18.9991 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 21.3174 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 25.8870 | 4 | 4 |
| G | Vesicular stomatitis virus | Potency | 9.5221 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 9.5221 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 9.5221 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 9.5221 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 19.0115 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | IC50 | 74.5300 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 11.1800 | 1 | 1 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 | 400.0000 | 1 | 1 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 400.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily KQT member 2 | Homo sapiens (human) | Activity | 0.3200 | 1 | 1 |
| Potassium voltage-gated channel subfamily KQT member 2 | Homo sapiens (human) | EC2 | 0.3300 | 1 | 1 |
| Potassium voltage-gated channel subfamily KQT member 3 | Homo sapiens (human) | Activity | 0.3200 | 1 | 1 |
| Potassium voltage-gated channel subfamily KQT member 3 | Homo sapiens (human) | EC2 | 0.3350 | 2 | 2 |
| Potassium voltage-gated channel subfamily KQT member 5 | Homo sapiens (human) | EC2 | 0.3400 | 1 | 1 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | Km | 460.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | Km | 322.0000 | 2 | 2 |