Disruptive, Impulse Control, and Conduct Disorders

Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.

Synonym
Kleptomania
Disruptive, Impulse Control, and Conduct Disorders
Impulse Control Disorders
Intermittent Explosive Disorder
Impulse-Control Disorders

Excerpt	Reference
"Kleptomania is currently classified in psychiatric nomenclature as one of the impulse control disorders (DSM-IV, 1994)."	( Durst, R; Jabotinsky-Rubin, K; Katz, G; Knobler, HY, 1997)
"Finally, impulse control disorders are suggested as being pure adverse side-effects of dopamine replacement therapy."	( van den Heuvel, OA; van der Werf, YD; Wolters, ECh, 2008)
"Kleptomania is characterized by repetitive stealing of things not needed for personal use."	( Edel, MA; Hubert, C; Juckel, G; Rudel, A, 2009)
"Kleptomania is a rare psychiatric disorder characterized by recurrent stealing and for which there exists no empirically validated treatments."	( Grant, JE; Kim, SW; Odlaug, BL, 2009)
"Common impulse control disorders are compulsive buying, pathological gambling, binge eating, hypersexuality, and compulsive reckless driving."	( Jost, WH; Reiff, J, 2011)
"Impulse control disorders are common in Parkinson's disease, occurring in 13."	( Brezing, C; Dolan, RJ; Ekanayake, V; Fernandez, H; Gao, J; Hallett, M; Symmonds, M; Voon, V, 2011)
"Kleptomania is an impulse control disorder characterized by a recurrent failure to resist the impulse to steal worthless objects that are not needed for personal use."	( Belkız Güngör, B; Çetinay Aydın, P; Gülseren, L, 2012)
"Kleptomania is characterized by repetitive stealing behavior and has been associated with deleterious unwanted outcomes including forensic contact and increased rates of suicidal behavior."	( Chamberlain, SR; Grant, JE; Odlaug, BL; Schreiber, LR; Won Kim, S, 2013)
"Impulse control disorders are commonly associated with dopaminergic therapy in Parkinson's disease (PD)."	( Chakravartty, R; Harrison, N; Howell, NA; Mulholland, N; Ray Chaudhuri, K; Rizos, A; Robinson, S; Vivian, G; Voon, V, 2014)
"Kleptomania is an enigmatic condition and is among the very few psychiatric disorders in which crime is medicalised and used as a legal defence."	( Chan, LG; Dhaval, D; Saluja, B, 2014)
"Impulse control disorders are frequently associated with dopaminergic therapy in Parkinson's disease."	( Anheim, M; Ansquer, S; Azulay, JP; Bekadar, S; Benatru, I; Brefel-Courbon, C; Brice, A; Castrioto, A; Charbonnier-Beaupel, F; Cormier-Dequaire, F; Corvol, JC; Defebvre, L; Durif, F; Grabli, D; Krack, P; Kreisler, A; Krystkowiak, P; Lacomblez, L; Lagha-Boukbiza, O; Lebbah, S; Lebrun-Vignes, B; Lesage, S; Lhommée, E; Llorca, PM; Maltête, D; Mangone, G; Marques-Raquel, A; Ory-Magne, F; Pelissolo, A; Rascol, O; Roze, E; Tezenas du Montcel, S; Tir, M; Tranchant, C; Vidailhet, M, 2018)
"Kleptomania is a disease that shares features with obsessive compulsive spectrum disorders (OCD) and with substance abuse disorders (SAD)."	( Jahn, I; Olbrich, S; Stengler, K, 2019)

Excerpt	Reference
"Kleptomania has been found in association with major depression in a fairly large number of reports in recent years."	( Rocha, FL; Rocha, ME, 1992)
"Kleptomania has gone virtually non mentioned in the adolescent literature, despite the fact that kleptomania often has its onset during adolescence."	( Grant, JE; Kim, SW, 2002)
"Kleptomania has no definitive treatment."	( Aboujaoude, EN; Gamel, NN; Koran, LM, 2007)

Excerpt	Reference
"revised criteria for intermittent explosive disorder), without other psychiatric symptomatology clearly requiring treatment, were randomly assigned to levetiracetam or placebo, double-blind, for 10 weeks, at a variable dose with a maximum dose of 3000 mg/day."	( Mattes, JA, 2008)
"Finally, impulse control disorders are suggested as being pure adverse side-effects of dopamine replacement therapy."	( van den Heuvel, OA; van der Werf, YD; Wolters, ECh, 2008)
"We investigated impulsivity, impulse control disorders, and decision making in 50 untreated patients with primary RLS compared with 60 sex- and age-matched normal controls using one night of polysomnography recording, a structured psychiatric interview, and questionnaires (RLS Severity Scale, Beck Depression Inventory, and Urgency Premeditation Perseverance Impulsive Behavior Scale)."	( Bayard, S; Carlander, B; Dauvilliers, Y; Langenier, MC; Yu, H, 2010)
"Behavioural abnormalities such as impulse control disorders may develop when patients with Parkinson's disease receive dopaminergic therapy, although they can be controlled by deep brain stimulation of the subthalamic nucleus."	( Alegre, M; Artieda, J; Garcia-Garcia, D; Guridi, J; López-Azcárate, J; Obeso, JA; Rodriguez-Oroz, MC; Toledo, J; Valencia, M, 2011)
"Early recognition of impulse control disorders in Parkinson's disease is important and a close collaboration between the neurologist and the psychiatrist is essential in order to ensure correct diagnosis and the best possible treatment."	( Berendse, HW; Foncke, EM; Groenewegen, HJ; Van den Heuvel, OA; Van der Werf, YD, 2011)
"Clearly, impulse control disorders can occur without an induction of any drugs, and they may lead to very problematic situations that affect the adjustment of the patient and need to be treated immediately."	( Atmaca, M, 2014)
"Pathological Gambling (PG) and other Impulse Control Disorders (ICDs) have emerged as iatrogenic complications associated with dopamine replacement therapy."	( Bentivoglio, AR; Conte, G; De Risio, L; Di Nicola, M; Fasano, A; Janiri, L; Loria, G; Martinotti, G; Pettorruso, M; Ricciardi, L, 2014)
"Clinicians are increasingly recognizing impulse control disorders (ICDs) as a complication of dopaminergic treatment in Parkinson's disease (PD)."	( Asano, K; Kobayashi, S; Matsuda, N; Ugawa, Y, 2019)
"In the treatment of kleptomania, only naltrexone was effective."	( Maaz, M; Naidoo, Y; Naufal, R; Tahir, R; Tahir, T; Wong, MM, 2022)
"To asses risk of new-onset impulse control disorders (ICDs) in patients with Cushing's disease (CD) who initiated cabergoline (CBG) and to determine frequency of ICDs in CBG-treated patients with CD."	( Ciftci, S; Ersungur, EB; Gul, N; Kadioglu, P; Ozkaya, HM; Poyraz, BC; Sahin, S; Sarac, B; Sulu, C; Tanrikulu, S; Tanriover, E; Yener Ozturk, F, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	21 (3.44)	23.3326
1990's	57 (9.33)	12.5806
2000's	242 (39.61)	18.1394
2010's	240 (39.28)	28.8240
2020's	51 (8.35)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	3	0
carbon monoxide	medium	2	2
carnitine	low	1	0
choline	medium	2	1
salicylic acid	low	1	0
bupropion	medium	4	1
creatine	medium	2	1
dihydroxyphenylalanine	low	1	0
kynurenine	low	1	0
inositol	low	1	0
taurine	low	2	0
uric acid	low	1	0
8-hydroxy-2-(di-n-propylamino)tetralin	low	1	0
1-(3-chlorophenyl)piperazine	low	2	0
3,4-methylenedioxyamphetamine	low	1	0
n-methyl-3,4-methylenedioxyamphetamine	medium	5	1
homovanillic acid	low	6	0
phenytoin	medium	2	2
hydroxyindoleacetic acid	low	17	0
alprazolam	low	1	0
amantadine	medium	8	1
amitriptyline	low	1	0
benserazide	low	1	0
buspirone	medium	4	2
caffeine	low	1	0
carbamazepine	medium	10	3
cetirizine	medium	1	1
citalopram	medium	13	7
clomipramine	low	6	0
clonidine	medium	2	1
dantrolene	low	1	0
amphetamine	low	3	0
diazepam	low	1	0
dichlorodiphenyl dichloroethylene	low	1	0
valproic acid	medium	14	4
fenfluramine	medium	4	3
fluoxetine	medium	17	5
gabapentin	low	1	0
haloperidol	medium	5	2
imipramine	low	1	0
ketamine	low	1	0
kynurenic acid	low	1	0
lamotrigine	medium	5	2
lorazepam	medium	3	1
memantine	medium	1	1
methadone	medium	2	1
methylphenidate	medium	12	1
mianserin	low	1	0
mirtazapine	low	1	0
modafinil	low	1	0
nefazodone	medium	3	2
oxidopamine	low	3	0
oxybutynin	low	1	0
perphenazine	low	1	0
piracetam	medium	2	2
pirenzepine	low	1	0
risperidone	medium	7	2
ropinirole	medium	16	1
temozolomide	low	1	0
trazodone	medium	1	1
trifluoperazine	medium	1	1
zonisamide	low	4	0
alanine	low	1	0
aspartic acid	medium	2	1
apomorphine	low	5	0
carbostyril	low	5	0
levodopa	medium	71	3
tyrosine	low	2	0
phenylalanine	low	1	0
tryptophan	medium	9	1
cyclohexanol	low	4	0
thiophenes	low	9	0
1-naphthylamine	low	2	0
isoxazoles	low	4	0
thiazoles	medium	3	1
cyproterone acetate	low	1	0
dihydrotestosterone	low	1	0
methoxyhydroxyphenylglycol	low	7	0
methamphetamine	medium	3	1
lithium carbonate	medium	6	2
s,n,n'-tripropylthiocarbamate	medium	81	2
dronabinol	low	1	0
flupenthixol	low	1	0
tranylcypromine	medium	1	1
manganese	low	1	0
trolamine salicylate	low	1	0
selegiline	low	1	0
bromocriptine	medium	3	1
cetylpyridinium chloride anhydrous	medium	1	1
glutamic acid	low	2	0
oxcarbazepine	medium	2	1
5,7-dihydroxytryptamine	low	1	0
paroxetine	medium	12	3
captopril	medium	1	1
pergolide	low	5	0
fenoxycarb	low	1	0
simvastatin	low	1	0
cabergoline	low	6	0
atomoxetine hydrochloride	low	3	0
fluorodopa f 18	low	1	0
naxagolide	low	1	0
n 0437, (-)-isomer	low	7	0
tiagabine	medium	1	1
aripiprazole	low	15	0
duloxetine hydrochloride	low	2	0
ziprasidone	medium	2	1
venlafaxine hydrochloride	low	5	0
oseltamivir	low	1	0
n-acetylaspartic acid	low	1	0
triazoles	medium	3	2
fluorodeoxyglucose f18	medium	12	1
sertraline	medium	9	2
acamprosate	low	2	0
s20098	low	1	0
nicotine	medium	7	3
carbidopa, levodopa drug combination	medium	4	1
pramipexole	medium	25	2
safinamide	low	1	0
angiotensin ii	medium	1	1
lithium chloride	low	2	0
cocaine	low	12	0
sodium bicarbonate	low	1	0
cotinine	low	1	0
D-fructopyranose	medium	6	2
pica	low	1	0
lithium	medium	5	2
raclopride	low	1	0
rasagiline	low	4	0
tolcapone	low	1	0
dinoprost	low	1	0
entacapone	low	1	0
8-epi-prostaglandin f2alpha	low	1	0
phenylephrine hydrochloride	low	5	0
cyproterone	low	1	0
levetiracetam	medium	2	2
nalmefene	medium	6	2
naloxone	low	1	0
topiramate	medium	6	2
istradefylline	low	1	0
mdl 100907	low	1	0
fluvoxamine	medium	12	2
naltrexone	medium	32	10
heroin	low	1	0
phosphocreatine	low	1	0
stalevo	low	1	0
paliperidone palmitate	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	2	0
alpha-synuclein	low	3	0
lurasidone hydrochloride	low	1	0
lisdexamfetamine dimesylate	low	1	0
lorcaserin	medium	1	1
brexpiprazole	low	1	0
cholecystokinin	low	1	0
beta-endorphin	low	1	0
neuropeptide y	low	1	0
sodium ethylxanthate	low	1	0
quetiapine fumarate	medium	4	1
interleukin-8	low	1	0
nitrophenols	low	1	0
exudates	low	3	0
deoxyguanosine	low	1	0
clozapine	medium	3	2
olanzapine	medium	6	2
8-hydroxy-2'-deoxyguanosine	low	1	0
phosphocreatinine	low	1	0
carbidopa	medium	7	1
ego	medium	2	1
leptin	low	2	0

Protein Targets (1,213)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
5-hydroxytryptamine receptor 3E	0	8	0	8
acetylcholinesterase	19	0	0	19
TDP1 protein	47	0	0	47
cytochrome P450 2D6	37	0	0	37
v-jun sarcoma virus 17 oncogene homolog (avian)	27	0	0	27
cytochrome P450 2D6 isoform 1	20	0	0	20
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C19 precursor	16	0	0	16
cytochrome P450 2C9 precursor	13	0	0	13
thyroid hormone receptor beta isoform a	12	0	0	12
thyroid hormone receptor beta isoform 2	43	0	0	43
huntingtin isoform 2	5	0	0	5
peripheral myelin protein 22	28	0	0	28
cytochrome P450 3A4 isoform 1	20	0	0	20
muscarinic acetylcholine receptor M1	27	0	0	27
Gamma-aminobutyric acid receptor subunit pi	20	9	1	30
Polyunsaturated fatty acid lipoxygenase ALOX15B	11	0	0	11
ATP-binding cassette sub-family C member 3	0	43	0	43
Multidrug resistance-associated protein 4	0	43	0	43
5-hydroxytryptamine receptor 3B	0	8	0	8
Bile salt export pump	0	59	0	59
Beta-1 adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 1A	0	26	13	40
5-hydroxytryptamine receptor 2C	0	32	3	35
D(2) dopamine receptor	0	47	11	66
5-hydroxytryptamine receptor 2A	0	36	3	40
Gamma-aminobutyric acid receptor subunit beta-1	20	9	1	30
Alpha-1B adrenergic receptor	0	30	4	34
Gamma-aminobutyric acid receptor subunit delta	20	9	1	30
Gamma-aminobutyric acid receptor subunit gamma-2	20	9	2	31
D	0	23	0	23
5-hydroxytryptamine receptor 1A	0	40	4	46
Gamma-aminobutyric acid receptor subunit alpha-5	20	9	1	30
Gamma-aminobutyric acid receptor subunit alpha-3	20	9	1	30
Gamma-aminobutyric acid receptor subunit gamma-1	20	9	1	30
Gamma-aminobutyric acid receptor subunit alpha-2	20	9	1	30
Alpha-1D adrenergic receptor	0	28	4	33
5-hydroxytryptamine receptor 2A	0	40	7	50
5-hydroxytryptamine receptor 2C	0	37	5	42
Gamma-aminobutyric acid receptor subunit alpha-4	20	9	1	30
Gamma-aminobutyric acid receptor subunit gamma-3	20	9	1	30
5-hydroxytryptamine receptor 1B	0	28	2	31
5-hydroxytryptamine receptor 1D	0	17	2	20
Gamma-aminobutyric acid receptor subunit alpha-6	20	9	1	30
5-hydroxytryptamine receptor 1F	0	17	2	20
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	30	4	34
Sodium-dependent serotonin transporter	0	46	9	55
5-hydroxytryptamine receptor 7	0	16	2	18
5-hydroxytryptamine receptor 7	0	16	0	16
Alpha-1B adrenergic receptor	0	10	1	12
Glutamate receptor ionotropic, NMDA 1	0	15	1	21
5-hydroxytryptamine receptor 2B	0	39	4	43
Alpha-1A adrenergic receptor	0	32	5	37
5-hydroxytryptamine receptor 3A	0	11	0	11
Histamine H2 receptor	19	4	0	26
5-hydroxytryptamine receptor 6	0	28	0	30
Beta-2 adrenergic receptor	0	1	0	1
D(2) dopamine receptor	0	38	6	44
Gamma-aminobutyric acid receptor subunit alpha-1	20	9	2	31
Gamma-aminobutyric acid receptor subunit beta-3	20	9	1	30
Gamma-aminobutyric acid receptor subunit beta-2	20	9	2	31
Glutamate receptor ionotropic, NMDA 2A	0	13	1	19
Glutamate receptor ionotropic, NMDA 2B	0	15	1	21
Glutamate receptor ionotropic, NMDA 2C	0	13	1	19
Glutamate receptor ionotropic, NMDA 2D	0	13	1	19
5-hydroxytryptamine receptor 3D	0	8	0	8
Glutamate receptor ionotropic, NMDA 3B	0	13	1	19
5-hydroxytryptamine receptor 3C	0	8	0	8
GABA theta subunit	20	9	1	30
Canalicular multispecific organic anion transporter 1	0	40	0	40
Gamma-aminobutyric acid receptor subunit epsilon	20	9	1	30
Glutamate receptor ionotropic, NMDA 3A	0	13	1	19
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
RAR-related orphan receptor gamma	36	0	0	36
GLI family zinc finger 3	43	0	0	43
AR protein	52	0	0	52
aldehyde dehydrogenase 1 family, member A1	22	0	0	22
thyroid stimulating hormone receptor	20	0	0	20
estrogen receptor 2 (ER beta)	26	0	0	26
nuclear receptor subfamily 1, group I, member 3	39	0	0	39
progesterone receptor	27	0	0	27
glucocorticoid receptor [Homo sapiens]	43	0	0	43
retinoic acid nuclear receptor alpha variant 1	39	0	0	39
estrogen-related nuclear receptor alpha	41	0	0	41
pregnane X nuclear receptor	37	0	0	37
estrogen nuclear receptor alpha	58	0	0	58
aryl hydrocarbon receptor	17	0	0	17
thyroid stimulating hormone receptor	19	0	0	19
activating transcription factor 6	11	0	0	11
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	20	0	0	20
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	37	0	0	37
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Glutamate receptor 2	21	3	2	27
Kelch-like ECH-associated protein 1	0	0	1	1
Histone acetyltransferase KAT8	0	1	0	1
Sodium-dependent dopamine transporter	0	33	5	38
Sodium-dependent noradrenaline transporter	0	39	6	45
Sodium-dependent dopamine transporter	0	24	2	26
5-hydroxytryptamine receptor 6	0	8	2	10
Sodium-dependent serotonin transporter	0	22	4	27
5-hydroxytryptamine receptor 5A	0	8	2	10
5-hydroxytryptamine receptor 5B	0	8	2	10
5-hydroxytryptamine receptor 3A	0	12	2	14
5-hydroxytryptamine receptor 4	0	8	2	10
5-hydroxytryptamine receptor 3B	0	12	2	14
phosphopantetheinyl transferase	20	0	0	20
euchromatic histone-lysine N-methyltransferase 2	57	0	0	57
mu-type opioid receptor isoform MOR-1	0	0	4	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
5-hydroxytryptamine receptor 2A	0	0	4	4
Cytochrome P450 3A4	0	20	1	24
Neuronal acetylcholine receptor subunit alpha-4	2	6	3	12
Cytochrome P450 2C9	0	14	0	15
Neuronal acetylcholine receptor subunit beta-2	2	6	3	12
Translocator protein	0	5	1	7
D(3) dopamine receptor	0	20	1	21
Alpha-2B adrenergic receptor	0	22	2	25
D(2) dopamine receptor	0	12	0	12
Alpha-2C adrenergic receptor	0	22	2	25
Alpha-2A adrenergic receptor	0	22	2	25
Alpha-1D adrenergic receptor	0	30	1	32
5-hydroxytryptamine receptor 1D	0	3	0	5
5-hydroxytryptamine receptor 1B	0	2	1	3
Alpha-1A adrenergic receptor	0	14	1	16
5-hydroxytryptamine receptor 5A	0	3	0	3
5-hydroxytryptamine receptor 7	0	9	0	9
D	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	32	0	32
Lysosomal alpha-glucosidase	0	2	0	2
Transporter	0	23	1	25
ATP-dependent phosphofructokinase	31	0	0	31
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	11	0	0	11
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	4	0	4
thioredoxin reductase	29	0	0	29
GALC protein	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	34	0	0	34
retinoid X nuclear receptor alpha	27	0	0	27
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
arylsulfatase A	26	0	0	26
Carbonic anhydrase	0	3	0	3
Bloom syndrome protein isoform 1	17	0	0	17
geminin	43	0	0	43
survival motor neuron protein isoform d	11	0	0	11
muscleblind-like protein 1 isoform 1	4	0	0	4
Carbonic anhydrase	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	8	1	17
Prolyl endopeptidase	0	3	0	3
Carbonic anhydrase-related protein 11	0	1	0	3
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	4	0	4
Carbonic anhydrase 1	0	12	1	26
Carbonic anhydrase 2	0	12	3	27
Carbonic anhydrase 2	0	3	0	3
Cytochrome P450 1A2	0	6	1	8
Carbonic anhydrase 3	0	7	1	14
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2D6	0	15	0	18
Cytochrome P450 2A6	0	7	1	8
Androgen receptor	0	10	1	11
Cannabinoid receptor 1	0	3	1	4
Arachidonate 5-lipoxygenase-activating protein	0	3	0	3
Cytochrome P450 2B6	0	3	1	6
Carbonic anhydrase 4	0	8	1	16
Carbonic anhydrase 6	0	7	1	15
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	11	0	15
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	6	1	12
Delta-type opioid receptor	0	9	2	13
Cytochrome P450 2C19	0	9	0	11
Delta-type opioid receptor	0	9	3	12
Mu-type opioid receptor	0	11	4	15
Carbonic anhydrase 5A, mitochondrial	0	8	3	19
Carbonic anhydrase	0	3	0	7
Kappa-type opioid receptor	0	8	1	10
Carbonic anhydrase 7	0	7	1	15
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	9	2	0	11
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	3	0	7
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Mu-type opioid receptor	0	9	4	14
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	3	0	3
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	6	2	9
Carbonic anhydrase 9	0	9	1	18
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	3	0	7
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase	0	3	0	3
Sigma intracellular receptor 2	0	9	0	9
Delta carbonic anhydrase	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Renin	0	1	0	1
Carbonic anhydrase	0	3	0	7
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	6	1	9
Carbonic anhydrase 4	0	4	0	6
Carbonic anhydrase 15	0	4	0	9
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	4	0	10
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	7	1	16
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	8	1	17
Chain A, JmjC domain-containing histone demethylation protein 3A	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	7	0	0	7
pregnane X receptor	6	0	0	6
USP1 protein, partial	18	0	0	18
NFKB1 protein, partial	12	0	0	12
Microtubule-associated protein tau	18	0	0	18
Thrombopoietin	7	0	0	7
regulator of G-protein signaling 4	30	0	0	30
farnesoid X nuclear receptor	21	0	0	21
vitamin D (1,25- dihydroxyvitamin D3) receptor	21	0	0	21
D(1A) dopamine receptor	28	0	0	28
heat shock protein beta-1	12	0	0	12
flap endonuclease 1	11	0	0	11
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	4	0	4
Guanine nucleotide-binding protein G	4	0	0	4
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
Ataxin-2	30	0	0	30
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
Alanine racemase, biosynthetic	0	0	0	1
Proton-coupled amino acid transporter 1	0	4	0	4
Adenosine deaminase	0	0	0	1
peroxisome proliferator activated receptor gamma	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	26	0	0	26
nuclear receptor ROR-gamma isoform 1	17	0	0	17
lamin isoform A-delta10	36	0	0	36
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	8	4	12
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	2	9
Cholecystokinin receptor type A	1	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	8	4	12
Gamma-aminobutyric acid receptor subunit alpha-3	0	8	3	11
Gamma-aminobutyric acid receptor subunit alpha-2	0	8	3	11
Gamma-aminobutyric acid receptor subunit beta-2	0	8	2	10
Cholecystokinin receptor type A	0	3	0	3
ATPase family AAA domain-containing protein 5	18	0	0	18
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
EWS/FLI fusion protein	23	0	0	23
putative alpha-glucosidase	1	0	0	1
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Solute carrier family 22 member 2	0	5	0	9
Solute carrier family 22 member 1	0	10	0	15
Glutamate receptor ionotropic, NMDA 2D	0	5	0	5
Glutamate receptor ionotropic, NMDA 3B	0	5	0	5
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	33	1	1	35
Glutamate receptor ionotropic, NMDA 1	0	7	0	7
Glutamate receptor ionotropic, NMDA 2A	0	7	0	7
Glutamate receptor ionotropic, NMDA 2B	0	7	0	7
Glutamate receptor ionotropic, NMDA 2C	0	5	0	5
Solute carrier family 22 member 1	0	5	0	7
Glutamate receptor ionotropic, NMDA 3A	0	5	0	5
Multidrug and toxin extrusion protein 1	0	7	0	7
Solute carrier family 22 member 2	0	4	0	6
GLS protein	30	0	0	30
chromobox protein homolog 1	31	0	0	31
atrial natriuretic peptide receptor 2 precursor	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
5-hydroxytryptamine receptor 4	0	26	0	26
Albumin	0	0	9	9
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	23	0	23
Muscarinic acetylcholine receptor M2	0	22	2	25
Muscarinic acetylcholine receptor M4	0	22	1	23
Muscarinic acetylcholine receptor M1	0	11	0	11
Muscarinic acetylcholine receptor M3	0	10	0	10
Muscarinic acetylcholine receptor M4	0	10	0	10
Muscarinic acetylcholine receptor M5	0	11	0	11
Muscarinic acetylcholine receptor M5	0	24	0	24
Alpha-2A adrenergic receptor	0	33	1	34
Muscarinic acetylcholine receptor M2	0	10	0	10
Muscarinic acetylcholine receptor M1	0	25	3	30
Angiotensin-converting enzyme	0	22	0	23
Alpha-2B adrenergic receptor	0	33	1	34
Alpha-2C adrenergic receptor	0	29	1	30
Muscarinic acetylcholine receptor M3	0	25	1	26
D(1A) dopamine receptor	0	25	5	34
D(1B) dopamine receptor	0	8	1	12
UDP-glucuronosyltransferase 1A4	0	1	0	6
Histamine H2 receptor	0	13	2	15
Histamine H1 receptor	0	8	0	8
Histamine H1 receptor	0	26	4	33
D(3) dopamine receptor	0	38	7	51
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	7	0	10
UDP-glucuronosyltransferase 1A3	0	0	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	3	0	3
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Potassium voltage-gated channel subfamily H member 2	0	37	0	37
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	10
Sodium channel protein type 5 subunit alpha	0	7	0	7
Sodium channel protein type 9 subunit alpha	0	8	0	8
Nuclear receptor subfamily 3 group C member 3	0	19	0	19
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	6	0	6
Sodium channel protein type 10 subunit alpha	0	4	0	4
Solute carrier family 22 member 3	0	2	0	2
Phenylethanolamine N-methyltransferase	0	2	0	2
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	3	0	3
Beta-2 adrenergic receptor	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	11	0	11
glucocerebrosidase	6	0	0	6
DNA polymerase kappa isoform 1	13	0	0	13
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Luciferase	12	0	0	12
hypoxia-inducible factor 1 alpha subunit	16	0	0	16
peroxisome proliferator-activated receptor delta	21	0	0	21
Histone H2A.x	12	0	0	12
vitamin D3 receptor isoform VDRA	18	0	0	18
potassium voltage-gated channel subfamily H member 2 isoform d	27	0	0	27
mitogen-activated protein kinase 1	16	0	0	16
lethal factor (plasmid)	12	0	0	12
Cellular tumor antigen p53	35	0	0	35
Integrin beta-3	4	0	1	5
Integrin alpha-IIb	4	0	1	5
Tryptophan 5-hydroxylase 1	0	4	0	4
D(4) dopamine receptor	0	20	4	29
D(1B) dopamine receptor	0	12	0	12
D(4) dopamine receptor	0	14	1	15
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	10	0	10
SMAD family member 2	8	0	0	8
Fumarate hydratase	15	0	0	15
PPM1D protein	6	0	0	6
SMAD family member 3	8	0	0	8
G	21	0	0	21
polyprotein	15	0	0	15
67.9K protein	8	0	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	7	0	0	7
lysosomal alpha-glucosidase preproprotein	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
transcriptional regulator ERG isoform 3	7	0	0	7
neuropeptide S receptor isoform A	5	0	0	5
5-hydroxytryptamine receptor 3A	0	2	1	3
Interferon beta	26	0	0	26
HLA class I histocompatibility antigen, B alpha chain	21	0	0	21
ATP-dependent translocase ABCB1	0	13	0	19
Histamine H1 receptor	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	6	0	6
Inositol monophosphatase 1	14	0	0	14
Multidrug and toxin extrusion protein 2	0	4	0	4
Inositol hexakisphosphate kinase 1	21	0	0	21
cytochrome P450 2C9, partial	21	0	0	21
Chain A, Ferritin light chain	9	0	0	9
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	6
glp-1 receptor, partial	13	0	0	13
IDH1	12	0	0	12
M-phase phosphoprotein 8	12	0	0	12
Zinc finger protein mex-5	0	0	1	1
POsterior Segregation	0	0	1	1
Genome polyprotein	0	1	0	1
Replicase polyprotein 1ab	0	4	1	5
Hexokinase-2	0	1	0	1
Genome polyprotein	0	1	1	2
ATAD5 protein, partial	17	0	0	17
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Alpha-synuclein	2	4	0	6
Kappa-type opioid receptor	0	9	3	17
Acetylcholine receptor subunit alpha	0	3	1	4
Acetylcholine receptor subunit gamma	0	3	1	4
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	3	1	4
UDP-glucuronosyltransferase 2B7	0	3	0	6
Neuronal acetylcholine receptor subunit beta-2	0	3	1	5
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Neuronal acetylcholine receptor subunit beta-4	0	3	1	5
Neuronal acetylcholine receptor subunit alpha-3	0	3	1	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	6
Neuronal acetylcholine receptor subunit alpha-4	0	3	1	5
Acetylcholine receptor subunit delta	0	3	1	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
Bile salt export pump	0	7	0	7
Beta-2 adrenergic receptor	0	5	0	5
Angiotensin-converting enzyme	0	3	1	4
Beta-1 adrenergic receptor	0	4	0	4
Beta-3 adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	2	0	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
DNA polymerase beta	2	0	0	2
Potassium channel subfamily K member 2	0	2	1	3
Cholinesterase	0	5	0	5
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	3	1	4
Adenosine receptor A3	0	4	0	4
Amine oxidase [flavin-containing] A	0	11	0	12
Acetylcholinesterase	0	9	0	9
Amine oxidase [flavin-containing] B	0	14	3	18
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	6	2	9
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A2b	0	3	1	5
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	2	1	4
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Guanine deaminase	0	2	0	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
thioredoxin glutathione reductase	5	0	0	5
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	11	0	0	11
transient receptor potential cation channel subfamily V member 1	4	0	0	4
Prothrombin	0	1	1	2
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	4	0	4
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	4	1	5
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	1
TAR DNA-binding protein 43	11	0	0	11
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	1	3
Beta-lactamase class B VIM-2	0	1	1	2
Vpr	4	0	0	4
Major prion protein	0	0	3	3
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2J2	0	9	0	10
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	3	0	3
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Angiopoietin-1 receptor	0	0	1	1
Histamine H4 receptor	0	3	2	5
caspase 7, apoptosis-related cysteine protease	9	0	0	9
caspase-3	9	0	0	9
thyrotropin-releasing hormone receptor	3	0	0	3
Caspase-2	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Sodium-dependent noradrenaline transporter	0	4	0	4
Aldo-keto reductase family 1 member B1	0	4	0	4
Aromatase	0	1	0	1
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	6	0	6
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Transmembrane protease serine 2	0	1	1	2
Procathepsin L	0	1	1	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Trypanothione reductase	0	4	0	4
Trypanothione reductase	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	1
Envelope glycoprotein	0	0	4	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Cruzipain	4	0	0	4
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	0	1	1
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 3	0	3	0	3
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Nischarin	0	2	0	2
Nischarin	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
Adenylate cyclase type 1	0	2	0	2
DNA polymerase iota isoform a (long)	7	0	0	7
short transient receptor potential channel 6 isoform 1	0	0	1	1
Calmodulin-1	0	1	1	2
Endothelin receptor type B	0	2	0	2
Adenylate cyclase type 3	0	2	0	2
5-hydroxytryptamine receptor 3A	0	4	0	4
Endothelin receptor type B	0	2	0	2
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 2A	0	3	0	3
Adenylate cyclase type 8	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
D(2) dopamine receptor	0	4	0	4
Calmodulin	0	0	2	2
5-hydroxytryptamine receptor 2B	0	3	0	3
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	7	0	7
5-hydroxytryptamine receptor 1A	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Amyloid-beta precursor protein	1	3	0	4
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	7	1	8
Liver carboxylesterase 1	0	1	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	7	2	9
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	1	8
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Smad3	11	0	0	11
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Glucocorticoid receptor	0	3	0	4
Progesterone receptor	0	2	1	3
Glycine receptor subunit alpha-1	0	2	0	2
Androgen receptor	0	4	2	8
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Mu-type opioid receptor	0	13	5	22
Nuclear receptor ROR-gamma	5	0	0	5
ORF73	0	0	1	1
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Gastrin/cholecystokinin type B receptor	1	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
serine-protein kinase ATM isoform a	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
interleukin 8	2	0	0	2
Plasma kallikrein	0	1	0	5
Sex hormone-binding globulin	0	1	2	3
Progesterone receptor	0	1	0	1
Glucocorticoid receptor	0	1	0	1
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	1	0	1
Sex hormone-binding globulin	0	1	0	1
Aromatase	0	2	0	3
Androgen receptor	0	1	1	2
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Cannabinoid receptor 2	0	2	1	3
G-protein coupled bile acid receptor 1	0	0	1	1
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	0	1
endonuclease IV	5	0	0	5
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	3	0	0	3
core-binding factor subunit beta isoform 2	3	0	0	3
Epidermal growth factor receptor	0	2	0	2
Glutamate receptor 1	2	3	2	8
Glutamate receptor 3	2	3	2	8
Glutamate receptor 4	2	3	2	8
Caspase-7	1	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	1	2
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 6	0	1	0	3
Solute carrier family 22 member 7	0	0	0	2
Solute carrier family 22 member 8	0	2	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
apical membrane antigen 1, AMA1	4	0	0	4
hypothetical protein, conserved	2	0	0	2
nonstructural protein 1	6	0	0	6
pyruvate kinase	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
LacZ protein (plasmid)	0	0	1	1
Caspase-7	4	0	0	4
beta-2 adrenergic receptor	3	0	0	3
type-1 angiotensin II receptor	0	1	0	1
perilipin-5	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
perilipin-1	0	1	0	1
caspase-3	4	0	0	4
histone deacetylase 9 isoform 3	2	0	0	2
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
apelin receptor	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	2	3
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	2	0	2
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
C-X-C chemokine receptor type 2	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
Caspase-1	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Monoglyceride lipase	0	2	0	2
Gasdermin-D	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
heat shock protein 90, putative	0	0	0	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
L-lactate dehydrogenase A chain	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Cannabinoid receptor 1	0	2	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Cannabinoid receptor 2	0	2	1	4
Cannabinoid receptor 1	0	1	0	1
N-arachidonyl glycine receptor	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
G-protein coupled receptor 55	0	1	1	2
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	5
Catechol O-methyltransferase	0	2	0	2
Catechol O-methyltransferase	0	2	0	2
UDP-glucuronosyltransferase 2B15	0	0	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Estrogen receptor	0	2	1	4
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Estrogen receptor beta	0	1	1	3
Ghrelin O-acyltransferase	0	1	0	1
ras-related protein Rab-9A	6	0	0	6
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	3	1	6
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	3	1	5
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	3	1	5
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	3	0	4
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	3	0	4
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Cocaine esterase	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	2	0	2
Kappa-type opioid receptor	0	4	3	7
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
ClpP	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
alpha-galactosidase	2	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Snq2p	0	0	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
NPYLR7B	0	0	1	1
Acetylcholinesterase	0	3	0	3
Parkin	2	0	0	2
Mitogen-activated protein kinase 13	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Mitogen-activated protein kinase 12	0	1	0	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
Vesicular glutamate transporter 3	0	1	0	1
G-protein coupled receptor 35	0	2	1	3
Histamine H3 receptor	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
Polyphenol oxidase 2	0	1	0	4
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Tyrosinase	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	5
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
phosphoglycerate kinase	1	0	0	1
inositol monophosphatase 1	1	0	0	1
Glycogen synthase kinase-3 beta	0	1	1	2
5-hydroxytryptamine receptor 2C	0	0	1	1
Cysteinyl leukotriene receptor 1	0	1	0	1
Delta-type opioid receptor	0	7	4	15
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	2	0	2
Amine oxidase [flavin-containing] B	0	9	0	10
Amine oxidase [flavin-containing] B	0	4	0	4
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
Endothelin-1 receptor	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
G-protein coupled receptor	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
kappa-type opioid receptor isoform 1	0	1	0	1
Beta-galactosidase	0	0	1	1
Histidine decarboxylase	0	0	2	2
Kappa-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	6
UDP-glucuronosyltransferase 1A8	0	0	0	2
Nociceptin receptor	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Muscarinic acetylcholine receptor M4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
polyadenylate-binding protein 1	0	2	0	2
bcl-2-related protein A1	0	2	0	2
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Myeloperoxidase	0	2	0	2
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
NADPH oxidase 1	0	2	0	2
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Phospholipase A-2-activating protein	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
Amine oxidase [flavin-containing] A	0	7	0	8
Amine oxidase [flavin-containing] B	0	1	0	2
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Renin	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Cytochrome P450 2B1	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Amine oxidase [flavin-containing] A	0	0	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Melanocortin receptor 5	0	2	0	2
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	0	1
Tyrosine-protein kinase ABL2	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Transthyretin	0	1	1	2
Genome polyprotein	0	1	1	2
Krueppel-like factor 10	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Lysine-specific histone demethylase 1A	0	2	0	3
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 2E1	0	1	0	1
Cytochrome P450 4B1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Cytochrome P450 2A7	0	1	0	1
Cytochrome P450 3A7	0	1	0	1
Cytochrome P450 2F1	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Cytochrome P450 4F8	0	1	0	1
Cytochrome P450 4A11	0	1	0	1
Cytochrome P450 4F3	0	1	0	1
Cytochrome P450 4A22	0	1	0	1
Vitamin D 25-hydroxylase	0	1	0	1
Cytochrome P450 2U1	0	1	0	1
Cytochrome P450 2W1	0	1	0	1
Cytochrome P450 2S1	0	1	0	1
Cytochrome P450 3A43	0	1	0	1
REST corepressor 3	0	1	0	1
Genome polyprotein	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Beta-glucuronidase	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Protein kinase C theta type	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Disruptive, Impulse Control, and Conduct Disorders

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (611)

Protein Targets (1,213)

Disruptive, Impulse Control, and Conduct Disorders

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (611)

Drugs Studied (186)

Protein Targets (1,213)