Any molecule that contains four amino-acid residues connected by peptide linkages.
Member | Definition | Role |
acetyl-aspartyl-glutamyl-valyl-aspartal | A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7. | Ac-Asp-Glu-Val-Asp-H |
amastatin | A tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequence | amastatin |
carfilzomib | A synthetic tetrapeptide consisting of morpholin-4-acetyl, L-2-amino-4-phenylbutanoyl, L-leucyl and L-phenylalanyl residues joined in sequence with the C-terminus connected to the amino group of (2S)-2-amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-1-one via an amide linkage. Used for the treatment of patients with multiple myeloma | carfilzomib |
coelichelin | A tetrapeptide hydroxamate siderophore that is isolated from Streptomyces coelicolor. | coelichelin |
dolastatin 10 | A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization. | dolastatin 10 |
goralatide | A tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties. | Ac-Ser-Asp-Lys-Pro-OH; goralatide |
hc toxin | A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues. | HC toxin |
phenylalanyl-glycyl-leucyl-methioninamide | A tetrapeptide composed of L-phenylalanine, glycine, L-leucine, and L-methioninamide joined in sequence by peptide linkages. It is a C-terminal fragment of substance P. | L-Phe-Gly-L-Leu-L-Met-NH2 |
soblidotin | A tetrapeptide derivative of dolastatin 10. It is an inhibitor of tubulin polymerization which exhibits potent antitumor activity. | soblidotin |
succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamide | A tetrapeptide compound with a succinyl group at the N-terminal and a 7-amino-4-methylcoumarin group at the C-terminal. | succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin |
tetragastrin | A tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence. | tetragastrin |