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tetrapeptide

Any molecule that contains four amino-acid residues connected by peptide linkages.

ChEBI ID: 48030

Members (11)

MemberDefinitionRole
acetyl-aspartyl-glutamyl-valyl-aspartalA tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.Ac-Asp-Glu-Val-Asp-H
amastatinA tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequenceamastatin
carfilzomibA synthetic tetrapeptide consisting of morpholin-4-acetyl, L-2-amino-4-phenylbutanoyl, L-leucyl and L-phenylalanyl residues joined in sequence with the C-terminus connected to the amino group of (2S)-2-amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-1-one via an amide linkage. Used for the treatment of patients with multiple myelomacarfilzomib
coelichelinA tetrapeptide hydroxamate siderophore that is isolated from Streptomyces coelicolor.coelichelin
dolastatin 10A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.dolastatin 10
goralatideA tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties.Ac-Ser-Asp-Lys-Pro-OH; goralatide
hc toxinA homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.HC toxin
phenylalanyl-glycyl-leucyl-methioninamideA tetrapeptide composed of L-phenylalanine, glycine, L-leucine, and L-methioninamide joined in sequence by peptide linkages. It is a C-terminal fragment of substance P.L-Phe-Gly-L-Leu-L-Met-NH2
soblidotinA tetrapeptide derivative of dolastatin 10. It is an inhibitor of tubulin polymerization which exhibits potent antitumor activity.soblidotin
succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamideA tetrapeptide compound with a succinyl group at the N-terminal and a 7-amino-4-methylcoumarin group at the C-terminal.succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin
tetragastrinA tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence.tetragastrin

Research

Studies (2,209)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990237 (10.73)18.7374
1990's551 (24.94)18.2507
2000's482 (21.82)29.6817
2010's652 (29.52)24.3611
2020's287 (12.99)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials229 (9.86%)5.53%
Reviews203 (8.74%)6.00%
Case Studies76 (3.27%)4.05%
Observational7 (0.30%)0.25%
Other1,807 (77.82%)84.16%